Pain Management Medications for Postoperative Pain
What You Need to Know Before You Apply
What is the purpose of this trial?
The primary purpose of the study is to determine adequacy of postoperative pain control after nasal surgery in patients prescribed Acetaminophen (325mg) + Hydrocodone (5mg) compared to Acetaminophen(325mg) + Ibuprofen (200mg)for a period of 5 days after nasal surgery. To assess the degree of pain, the participants will score the intensity of their pain on a visual analog scale(VAS)of 0-100points (0- no pain and 100- most severe pain), preoperatively and postoperatively (to be documented before each dose) for the duration of the prescribed medications .Additionally, the study will also seek to track:1. The total number of pills each patients consume from the prescribed 5 day regimen.2. Any associated side effects.3. Additional pain medications prescribed in case of inadequate pain control, postoperatively.
Will I have to stop taking my current medications?
The trial information does not specify if you need to stop taking your current medications. It's best to discuss this with the trial organizers or your doctor.
Is ibuprofen safe for managing postoperative pain?
How does the drug combination of Ibuprofen 200 mg and Tylenol 325 mg differ from other postoperative pain treatments?
This drug combination is unique because it uses both ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), and Tylenol (acetaminophen), which work together to manage pain without the side effects associated with opioids. Ibuprofen is effective for mild to moderate pain and has a longer duration of action compared to some other pain medications, while Tylenol is commonly used for pain relief and can reduce the need for stronger painkillers.16789
What data supports the effectiveness of the drugs used for postoperative pain management in the clinical trial?
Research shows that ibuprofen and acetaminophen are effective for managing postoperative pain, as seen in dental and orthopedic surgeries. Combining ibuprofen with acetaminophen has been recommended for acute pain relief, and ibuprofen alone has been found to be more effective than some opioid combinations for postoperative pain.157910
Who Is on the Research Team?
SAM P Most, MD
Principal Investigator
Stanford University
Are You a Good Fit for This Trial?
This trial is for adults over 18 who speak English and are having rhinoplasty either for cosmetic reasons or to treat nasal obstruction. It excludes pregnant or lactating women, those with allergies to pain meds used in the study, and anyone not undergoing nasal surgery.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either Norco or Tylenol with Ibuprofen for postoperative pain management for 5 days
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Ibuprofen 200 mg
- Norco 5Mg-325Mg Tablet
- Postoperative Pain Management
- Rhinoplasty
- Tylenol 325Mg Caplet
Find a Clinic Near You
Who Is Running the Clinical Trial?
Stanford University
Lead Sponsor