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Hyperpolarized Xenon MRI for Respiratory Disorders (HPXeMR Trial)

Phase 1 & 2

Recruiting

Led By Jason C. Woods, PhD

Research Sponsored by Children's Hospital Medical Center, Cincinnati

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Timeline

Screening 3 weeks

Treatment Varies

Follow Up day 1

Awards & highlights

HPXeMR Trial Summary

This trial will help researchers understand if hyperpolarized gas MRI can be used to assess regional lung function in children and adults with respiratory diseases.

Who is the study for?

This trial is for children and adults aged 6 or older who can hold their breath for up to 16 seconds. It's not suitable for pregnant individuals, those with recent respiratory infections, low oxygen levels without support, metal implants that interfere with MRI, heart defects, uncontrolled asthma, or claustrophobia.Check my eligibility

What is being tested?

The study tests the use of Hyperpolarized 129 Xenon gas during an MRI scan to assess lung function in healthy people as well as those with compromised lungs due to various diseases.See study design

What are the potential side effects?

While the document doesn't specify side effects, generally hyperpolarized xenon gas is considered safe but may cause dizziness or a feeling of lightheadedness during inhalation.

HPXeMR Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ day 1

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~day 1

This trial's timeline: 3 weeks for screening, Varies for treatment, and day 1 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Correlation of ventilated volume predictions obtained with 129Xe MRI vs. 1H MRI

HPXeMR Trial Design

1Treatment groups

Experimental Treatment

Group I: Hyperpolarized 129 XenonExperimental Treatment1 Intervention

Administration of up to 1 liter doses of Hyperpolarized Xenon gas during MRI (less for children) to optimize acquisition of images for children and adults vs. proton MR imaging

Do I qualify?Apply below to find out

Find a Location

Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

Children's Hospital Medical Center, CincinnatiLead Sponsor

815 Previous Clinical Trials

6,531,291 Total Patients Enrolled

1 Trials studying Respiratory Disorders

100 Patients Enrolled for Respiratory Disorders

Jason C. Woods, PhDPrincipal InvestigatorChildren's Hospital Medical Center, Cincinnati

Media Library

Hyperpolarized 129 Xenon Clinical Trial Eligibility Overview. Trial Name: NCT02272049 — Phase 1 & 2

Respiratory Disorders Research Study Groups: Hyperpolarized 129 Xenon

Respiratory Disorders Clinical Trial 2023: Hyperpolarized 129 Xenon Highlights & Side Effects. Trial Name: NCT02272049 — Phase 1 & 2

Hyperpolarized 129 Xenon 2023 Treatment Timeline for Medical Study. Trial Name: NCT02272049 — Phase 1 & 2

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are people with the specified medical condition able to join this clinical trial at this time?

"That is correct. The clinical trial mentioned is currently enrolling patients, as noted on the website. This particular study was posted December 1st, 2014 and last updated on December 17th, 2020; it plans to have 300 participants at one location."

Answered by AI

How many people suffering from this disease will be given the chance to try this treatment?

"Yes. The clinical trial, which was edited on December 17th 2020 and originally posted on December 1st 2014 is currently looking for 300 participants at 1 location, according to information available on clinicaltrials.gov"

Answered by AI

Does this study with Hyperpolarized 129 Xenon build on previous research?

"As of now, there are 15 clinical trials underway for Hyperpolarized 129 Xenon. 0 of those trials have reached Phase 3 status. Most of the research being conducted is based in Philadelphia, but there are studies taking place at 21 other locations."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Use of Hyperpolarized Xenon Gas for Lung Imaging in Children and Adults

2014. "Use of Hyperpolarized Xenon Gas for Lung Imaging in Children and Adults". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02272049.

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