What is Travatan
TravoprostThe Generic name of this drug
Treatment SummaryTravoprost ophthalmic solution is a medication used to control the progression of glaucoma and ocular hypertension by lowering the pressure inside the eyes. It is the first prostaglandin analog approved by the FDA for use as a first-line treatment for these conditions, and does not contain the preservative benzalkonium chloride. Travoprost is also approved for use in paediatric patients aged 2 months to 18 years with ocular hypertension or paediatric glaucoma in the EU.
Travatanis the brand name
Travatan Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Travatan
Travoprost
2001
15
Approved as Treatment by the FDA
Travoprost, also known as Travatan, is approved by the FDA for 3 uses such as Open Angle Glaucoma and Increased Intra Ocular Pressure (IOP) .Open Angle Glaucoma
Helps manage Open Angle Glaucoma (OAG)
Increased Intra Ocular Pressure (IOP)
Helps manage Increased Intra Ocular Pressure (IOP)
Ocular Hypertension
Helps manage Ocular Hypertension
Effectiveness
How Travatan Affects PatientsTravoprost is a type of medication that helps reduce eye pressure. It is a synthetic form of a natural substance in the body (prostaglandin F2 alpha) and is quickly broken down to its active form when applied to the eyes. This active form is very powerful and attaches to certain receptors in the eyes, reducing eye pressure.
How Travatan works in the bodyTravoprost helps to reduce pressure in the eyes. It works by binding to a receptor and allowing aqueous humour to flow out more easily. This process starts two hours after a dose and is at its strongest after 12 hours. The effects last for more than 24 hours with a single dose.
When to interrupt dosage
The amount of Travatan is contingent upon the identified condition, including Open Angle Glaucoma, Ocular Hypertension and Increased Intra Ocular Pressure (IOP). The dosage likewise depends upon the technique of delivery (e.g. Solution or Ophthalmic) noted in the following table.Condition
Dosage
Administration
Open Angle Glaucoma
, 0.04 mg/mL, 0.004 %, 0.03 mg/mL, 0.003 %
Solution, Ophthalmic, , Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic
Increased Intra Ocular Pressure (IOP)
, 0.04 mg/mL, 0.004 %, 0.03 mg/mL, 0.003 %
Solution, Ophthalmic, , Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic
Ocular Hypertension
, 0.04 mg/mL, 0.004 %, 0.03 mg/mL, 0.003 %
Solution, Ophthalmic, , Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic
Warnings
Travatan has one contraindication and should not be utilized if you are affected by any of the conditions present in the following table.Travatan ContraindicationsCondition
Risk Level
Notes
Attemping to get pregnant
Do Not Combine
Common Travatan Drug Interactions
Drug Name
Risk Level
Description
Acebutolol
Minor
Travoprost may increase the hypotensive activities of Acebutolol.
Aliskiren
Minor
Travoprost may increase the hypotensive activities of Aliskiren.
Alprenolol
Minor
Travoprost may increase the hypotensive activities of Alprenolol.
Ambrisentan
Minor
Travoprost may increase the hypotensive activities of Ambrisentan.
Amlodipine
Minor
Travoprost may increase the hypotensive activities of Amlodipine.
Travatan Toxicity & Overdose RiskNo cases of overdose have been reported for Travoprost. However, if a person accidentally ingests the drug, they should rinse their eyes with lukewarm water and be treated with supportive care. Travoprost is not recommended for pregnant women or those who are breastfeeding. It is also not advised for those under 16 years old and may reduce fertility. No adjustments in dosage are needed for those with mild to severe liver or kidney impairments.
Travatan Novel Uses: Which Conditions Have a Clinical Trial Featuring Travatan?
34 active studies are currently examining the possible effects of Travatan in reducing Ocular Hypertension, Intra Ocular Pressure (IOP) and Open Angle Glaucoma.Condition
Clinical Trials
Trial Phases
Increased Intra Ocular Pressure (IOP)
0 Actively Recruiting
Ocular Hypertension
23 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Phase 3, Phase 4
Open Angle Glaucoma
11 Actively Recruiting
Not Applicable, Phase 3, Phase 1, Phase 2
Travatan Reviews: What are patients saying about Travatan?
5Patient Review
6/5/2014 Travatan Z quickly and significantly lowered my eye pressure readings, which were previously quite high. I'm happy to report that after two weeks of treatment, my numbers are now well within the normal range.
5Patient Review
8/8/2011 This treatment is effective for glaucoma pressure. It's very expensive, so make sure to ask your doctor for samples if you don't have insurance coverage.
5Patient Review
8/8/2011 This medication is quite effective at managing glaucoma pressure. However, it is very expensive. If you don't have insurance coverage, be sure to ask your doctor for samples.
5Patient Review
8/2/2013 I've been using Travatan for years to great success. It lowers my pressure with fewer side effects and is simpler to use than most other options. That said, it can cause redness and a foreign body sensation in the eye that, while annoying, is a fair tradeoff for me compared to blindness.
5Patient Review
6/5/2014 Travatan Z quickly and significantly lowered my eye pressure readings, which were previously very high. I'm now at much less of a risk for blindness, and any side effects are more than worth it.
5Patient Review
8/2/2013 I've been using Travatan for years to great success. It lowers my pressure well and is simple to use, which are both big plusses in my book. Sometimes it causes redness and irritation, but that's a small price to pay compared to the alternative of blindness.
3.7Patient Review
7/31/2012 The drug is effective most of the time, but there have been a few instances where it's caused me pain or sinus problems.
3.7Patient Review
7/31/2012 On the whole, this drug is effective. There have been a few instances where it's stung upon application and sometimes I've had sinus trouble afterwards; however, those haven't been major problems.
3.3Patient Review
9/17/2014 After using Travatan for three months, my pressures did drop from 16 to 14; but after cataract surgery, still on the Travatan, I suddenly developed a blind spot on one eye which the ophthalmologist said is macular edema - a severe side effect resulting from the use of Travatan. So now I am slowly going blind...will NEVER touch Travatan again!
3.3Patient Review
9/17/2014 Travatan was effective in reducing my pressure after three months, but I suddenly developed macular edema (a severe side effect) which has resulted in blindness. I would never recommend this treatment to anyone.
3Patient Review
4/24/2011 I experienced increased sensitivity to light, eye pain, itchiness of the eyes, crustiness in the am when I wake up and eye pain.
3Patient Review
2/11/2012 I've just started this medication, and unfortunately my head hurts quite a bit. I have an unusual dual optic nerve which causes me a lot of pain and makes it difficult to see. Hopefully one of the doctors will be able to help me soon.
3Patient Review
3/9/2017 Travatan Z was successful in lowering my eye pressure from 26 and 32 to 21 and 26. I experienced no adverse effects during the three months I used it. My doctor wants me to continue the treatment with Betimol drops in the morning.
3Patient Review
2/11/2012 I just started this medication, and already I am experiencing headaches. Additionally, I have a very rare condition where I have two optic nerves in one eye; as a result, I am close to being blind. Right now, doctors are lining up to study my case. Hopefully, one of them will be able to help me with the pain that I am currently experiencing.
3Patient Review
4/24/2011 I found that this treatment made me more sensitive to light and gave me some eye pain. It wasn't too bad though, and the itchiness went away after a few days.
3Patient Review
3/9/2017 Before treatment, my pressures were 26 and 32. Now, after using Travatan Z for three months, they've decreased to 21 and 26 respectively with no negative side effects noted.
2.3Patient Review
4/15/2021 I took this medication for three years and it made me so dizzy that I could barely function. I told my doctor and they said that wasn't possible, but after doing some research I stopped taking the medication on my own. Now I'm not sure what to do next because I need shots in my eyes, but the doctor says if I don't take the medication then I won't get the shots.
2.3Patient Review
4/15/2021 I took this medication for three years, and during that time I felt more anxious and dizzy. I had to sleep all the time just to avoid feeling the side effects. When I told my doctor, they said it wasn't possible and that I needed to find another doctor.
2Patient Review
10/24/2012 Since starting this treatment a week ago, my blood pressure has become very unstable. It's extremely high in the morning and then drops too low in the evening. I didn't have any problems with blood pressure before starting this medication. Additionally, it feels like there's something sharp poking my eye from the inside and I've been getting headaches. I'm stopping use of this medication and will be consulting with another eye specialist for further help.
2Patient Review
8/22/2012 I started taking the medicine in January, using 1 drop per night. In about 3 months, my eye was red, dry, very painful and very sensitive to light. My eye doctor sent me to a specialist who've since then taken me off the medicine and gave me other eye drops. I even had to take pain killers because the pain was so bad. The problems still exist, and I'm having a little trouble reading and focusing even with my glasses on.
2Patient Review
12/19/2017 Travatan is very expensive, and I haven't found it to be effective. My vision has actually gotten worse since using it, and the sinus pressure that it's supposed to help with is almost unbearable. Of course, my ophthalmologist says not to stop using the drops, but I hate them.
2Patient Review
12/19/2017 Travatan is very expensive, and I haven't found it to be effective. My vision has actually gotten worse since starting the medication, and the sinus pressure that it's supposed to help with is almost unbearable. Of course, my ophthalmologist says not to stop using the drops.
2Patient Review
8/22/2012 I started taking the medicine in January, using 1 drop per night. In about 3 months, my eye was red,dry, very painful and very sensitive to light. My eye doctor sent me to a specialist who've since then taken me off the medicine and gave me other eye drops. I even had to take a pain killers, because the pain was so bad. The problems still exist, and I'm having a little trouble reading and focusing even with my glasses on.
2Patient Review
10/24/2012 I started using this treatment a week ago, and since then my blood pressure has become very unstable. It would be extremely high in the morning and then drop really low at night. I didn't have any problems with my blood pressure before starting this medication. Additionally, it feels like there's something sharp poking my eye, and I've been getting headaches. I'm stopping this medication and consulting with another eye specialist.
1.7Patient Review
9/12/2013 I experienced shockingly intense chest pain after just five days of use. This medication became increasingly intolerable the longer I took it.
1.7Patient Review
9/12/2013 I had terrible chest pain after just five days of using this medication. It got worse the longer I took it.
1.3Patient Review
6/21/2013 My doctor put me on this because Xalatan wasn't bringing my pressure down enough. However, after only four weeks I could barely see and both eyes felt foggy. I stopped taking the drops and she prescribed another medication. I'm not sure if Travatazn-x didn't damage my eyes or not.
1.3Patient Review
6/21/2013 My doctor put me on this because Xalatan wasn't bringing my pressure down enough to suit her. In about four weeks I could barely see out of my left eye and both eyes felt as thought I was looking through a fog, or a cloud. I stopped taking them and she put me on another drop. I'm not sure Travatazn-x hasn't really damaged my eyes.
1Patient Review
10/23/2013 After two nights of using this treatment, I felt terrible the next day. Chills, weakness, lightheadedness, and an overall feeling of lethargy. These symptoms persisted for about four or five hours before finally wearing off. Three days later, I tried the treatment again and had a similar experience. I will never use this product again.
1Patient Review
1/24/2016 Not only did this treatment not help, it actually made things worse. I now have constant headaches and can't stand bright lights. My eyes were sore to begin with, but after years of taking this medication they're even worse.
1Patient Review
9/6/2011 I experienced a lot of unpleasant side effects from this medication, including burning and pain in my nose, ear aches, congestion, and headaches. My eyes also felt very dry.
1Patient Review
10/23/2013 After two treatments, just twelve hours later I was feeling awful. Weakness, chills, my blood pressure and heart rate were both increased, and I felt overall terrible. These symptoms lasted for four to five hours before finally wearing off somewhat. However, I still felt too weak and lethargic to function the rest of the day. Three days later I decided to give the drops another try; unfortunately, I had a very similar experience
1Patient Review
1/24/2016 I have developed headaches and light sensitivity since beginning this treatment. My eyes were already sore from years of blindness, but I had gotten used to them. This just made things worse.
1Patient Review
9/6/2011 I experienced several side effects from this treatment, including burning and pain in my nose, ear aches, congestion, and headaches. My eyes also felt very dry.
Patient Q&A Section about travatan
Why is Travatan Z taken at night?
"For the best results, use your Travatan Eye Drops at the same time each evening before bed." - Anonymous Online Contributor
Unverified Answer
Why was Travatan discontinued?
"The ophthalmic solution Travoprost was stopped because it is thought to have caused the patient's sinus bradycardia, which is a slow heart rate." - Anonymous Online Contributor
Unverified Answer
What is Travatan eye drops used for?
"Travoprost is used in order to lower the high pressure inside the eye that is due to glaucoma or other eye diseases. This can help prevent blindness. The medication works by controlling the flow of fluid within the eye to keep a normal pressure." - Anonymous Online Contributor
Unverified Answer
Do they still make Travatan eye drops?
"is the last day that the Travatan brand name will be used in the United States. If the FDA has approved generic versions of this product, there may be generic equivalents available." - Anonymous Online Contributor
Unverified Answer