Travatan

Glaucoma, Open Angle Glaucoma, Ocular Hypertension
Treatment
6 FDA approvals
18 Active Studies for Travatan

What is Travatan

TravoprostThe Generic name of this drug
Treatment SummaryTravoprost ophthalmic solution is a medication used to control the progression of glaucoma and ocular hypertension by lowering the pressure inside the eyes. It is the first prostaglandin analog approved by the FDA for use as a first-line treatment for these conditions, and does not contain the preservative benzalkonium chloride. Travoprost is also approved for use in paediatric patients aged 2 months to 18 years with ocular hypertension or paediatric glaucoma in the EU.
Travatanis the brand name
image of different drug pills on a surface
Travatan Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Travatan
Travoprost
2001
15

Approved as Treatment by the FDA

Travoprost, also known as Travatan, is approved by the FDA for 6 uses such as Increased Intra Ocular Pressure (IOP) and Ocular Hypertension .
Increased Intra Ocular Pressure (IOP)
Helps manage Increased Intra Ocular Pressure (IOP)
Ocular Hypertension
Helps manage Ocular Hypertension
Open Angle Glaucoma (OAG)
Helps manage Open Angle Glaucoma (OAG)
Ocular Hypertension
Helps manage Ocular Hypertension
Open Angle Glaucoma
Helps manage Open Angle Glaucoma (OAG)
Glaucoma
Helps manage Increased Intra Ocular Pressure (IOP)

Effectiveness

How Travatan Affects PatientsTravoprost is a type of medication that helps reduce eye pressure. It is a synthetic form of a natural substance in the body (prostaglandin F2 alpha) and is quickly broken down to its active form when applied to the eyes. This active form is very powerful and attaches to certain receptors in the eyes, reducing eye pressure.
How Travatan works in the bodyTravoprost helps to reduce pressure in the eyes. It works by binding to a receptor and allowing aqueous humour to flow out more easily. This process starts two hours after a dose and is at its strongest after 12 hours. The effects last for more than 24 hours with a single dose.

When to interrupt dosage

The amount of Travatan is contingent upon the identified condition, including Open Angle Glaucoma, Ocular Hypertension and Increased Intra Ocular Pressure (IOP). The dosage likewise depends upon the technique of delivery (e.g. Solution or Ophthalmic) noted in the following table.
Condition
Dosage
Administration
Glaucoma
, 0.04 mg/mL, 0.004 %, 0.03 mg/mL, 0.003 %
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic
Open Angle Glaucoma
, 0.04 mg/mL, 0.004 %, 0.03 mg/mL, 0.003 %
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic
Ocular Hypertension
, 0.04 mg/mL, 0.004 %, 0.03 mg/mL, 0.003 %
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic

Warnings

Travatan has one contraindication and should not be utilized if you are affected by any of the conditions present in the following table.Travatan Contraindications
Condition
Risk Level
Notes
Attemping to get pregnant
Do Not Combine
There are 20 known major drug interactions with Travatan.
Common Travatan Drug Interactions
Drug Name
Risk Level
Description
Acebutolol
Minor
Travoprost may increase the hypotensive activities of Acebutolol.
Aliskiren
Minor
Travoprost may increase the hypotensive activities of Aliskiren.
Alprenolol
Minor
Travoprost may increase the hypotensive activities of Alprenolol.
Ambrisentan
Minor
Travoprost may increase the hypotensive activities of Ambrisentan.
Amlodipine
Minor
Travoprost may increase the hypotensive activities of Amlodipine.
Travatan Toxicity & Overdose RiskNo cases of overdose have been reported for Travoprost. However, if a person accidentally ingests the drug, they should rinse their eyes with lukewarm water and be treated with supportive care. Travoprost is not recommended for pregnant women or those who are breastfeeding. It is also not advised for those under 16 years old and may reduce fertility. No adjustments in dosage are needed for those with mild to severe liver or kidney impairments.
image of a doctor in a lab doing drug, clinical research

Travatan Novel Uses: Which Conditions Have a Clinical Trial Featuring Travatan?

34 active studies are currently examining the possible effects of Travatan in reducing Ocular Hypertension, Intra Ocular Pressure (IOP) and Open Angle Glaucoma.
Condition
Clinical Trials
Trial Phases
Open Angle Glaucoma
12 Actively Recruiting
Phase 3, Not Applicable, Phase 2, Phase 4, Phase 1
Glaucoma
0 Actively Recruiting
Ocular Hypertension
11 Actively Recruiting
Phase 3, Phase 4, Phase 1, Phase 2, Not Applicable

Travatan Reviews: What are patients saying about Travatan?

5Patient Review
6/5/2014
Travatan for Increased Pressure in the Eye
Travatan Z quickly and significantly lowered my eye pressure readings, which were previously quite high. I'm happy to report that after two weeks of treatment, my numbers are now well within the normal range.
5Patient Review
8/8/2011
Travatan for Increased Pressure in the Eye
This treatment is effective for glaucoma pressure. It's very expensive, so make sure to ask your doctor for samples if you don't have insurance coverage.
5Patient Review
8/8/2011
Travatan for Increased Pressure in the Eye
This medication is quite effective at managing glaucoma pressure. However, it is very expensive. If you don't have insurance coverage, be sure to ask your doctor for samples.
5Patient Review
8/2/2013
Travatan for Increased Pressure in the Eye
I've been using Travatan for years to great success. It lowers my pressure with fewer side effects and is simpler to use than most other options. That said, it can cause redness and a foreign body sensation in the eye that, while annoying, is a fair tradeoff for me compared to blindness.
5Patient Review
6/5/2014
Travatan for Increased Pressure in the Eye
Travatan Z quickly and significantly lowered my eye pressure readings, which were previously very high. I'm now at much less of a risk for blindness, and any side effects are more than worth it.
View All Reviews
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about travatan

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Why is Travatan Z taken at night?

"For the best results, use your Travatan Eye Drops at the same time each evening before bed."

Answered by AI

Why was Travatan discontinued?

"The ophthalmic solution Travoprost was stopped because it is thought to have caused the patient's sinus bradycardia, which is a slow heart rate."

Answered by AI

What is Travatan eye drops used for?

"Travoprost is used in order to lower the high pressure inside the eye that is due to glaucoma or other eye diseases. This can help prevent blindness. The medication works by controlling the flow of fluid within the eye to keep a normal pressure."

Answered by AI

Do they still make Travatan eye drops?

"is the last day that the Travatan brand name will be used in the United States. If the FDA has approved generic versions of this product, there may be generic equivalents available."

Answered by AI

Clinical Trials for Travatan

Have you considered Travatan clinical trials? We made a collection of clinical trials featuring Travatan, we think they might fit your search criteria.
Have you considered Travatan clinical trials? We made a collection of clinical trials featuring Travatan, we think they might fit your search criteria.
Have you considered Travatan clinical trials? We made a collection of clinical trials featuring Travatan, we think they might fit your search criteria.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top