AquaLumen Filtration Procedure for Glaucoma
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests a new surgical procedure called AquaLumen for individuals with moderate to severe open-angle glaucoma, a condition that increases eye pressure and can lead to vision loss. The goal is to determine if this procedure can lower eye pressure over a year. Individuals with a history of glaucoma and a specific corneal thickness may qualify. The trial excludes those who have undergone certain eye surgeries or have specific eye conditions. As an unphased trial, this study provides patients the opportunity to contribute to innovative research that could lead to new treatment options.
Do I need to stop taking my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that the AquaLumen Filtration Procedure is safe for glaucoma patients?
Research has shown that AquaLumen is safe for lowering eye pressure in people with glaucoma. In an earlier study, patients experienced a 40% to 45% reduction in eye pressure, a significant improvement over eye drops and comparable to other surgeries. Importantly, the treatment also greatly reduced the need for medications. Before the procedure, most patients used about three medications, but after 12 months, this number dropped to less than one. Many patients no longer needed medications soon after the treatment. These results suggest that AquaLumen is generally well-tolerated by patients.12345
Why are researchers excited about this trial?
Unlike the standard glaucoma treatments, which often rely on medications to decrease eye pressure, the AquaLumen Filtration Procedure is a surgical technique designed to improve fluid drainage from the eye. This procedure stands out because it offers a potentially more permanent solution by enhancing the eye's natural fluid outflow pathways. Researchers are excited about this approach as it could reduce the need for long-term medication use, which is a common burden for patients with glaucoma. By directly addressing the drainage issue, AquaLumen has the potential to offer more consistent and lasting control of eye pressure, which is crucial in preventing vision loss.
What evidence suggests that the AquaLumen procedure is effective for glaucoma?
Research has shown that the AquaLumen procedure, which participants in this trial will undergo, can lower eye pressure by 40% to 45%. This marks a significant improvement over standard eye drops. Patients with advanced glaucoma, including those already using the strongest available medications, demonstrated these results. The treatment has matched the effectiveness of other surgeries, suggesting that AquaLumen could be a strong option for managing glaucoma.12345
Are You a Good Fit for This Trial?
This clinical trial is for individuals with a condition called Open Angle Glaucoma, which increases pressure inside the eye. Participants should be those who require treatment to lower this pressure and are willing to undergo surgery.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Surgical Treatment
Participants undergo a surgical procedure intended to reduce intra-ocular pressure (IOP)
Follow-up
Participants are monitored for safety and effectiveness after the surgical procedure
What Are the Treatments Tested in This Trial?
Interventions
- AquaLumen
Find a Clinic Near You
Who Is Running the Clinical Trial?
PLU Ophthalmic
Lead Sponsor