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Radiotherapy vs. Surgery for Throat Cancer
Study Summary
This trial will compare surgery and radiation as treatments for a type of throat cancer not caused by HPV.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- My tumor is HPV-negative.I am 18 years old or older.I had head or neck cancer in the last 5 years.My recent blood tests show my liver, kidneys, and bone marrow are working well.I am a candidate for surgery aimed at curing my condition, with a high chance of removing all the cancer.My cancer is confirmed to be squamous cell carcinoma.I cannot attend all radiotherapy sessions or follow-up visits.I cannot or do not want to fill out quality of life questionnaires.My cancer originates in the oropharynx area.My cancer has spread to other parts of my body.I have health conditions that prevent me from undergoing surgery, chemotherapy, or radiotherapy.I have had radiation therapy on my head or neck before.I have been cancer-free for 5 years, except for non-melanoma skin cancer.I can take care of myself and am up and about more than half of my waking hours.My tumor is small and likely can be completely removed by surgery.My cancer has spread to my lymph nodes but can be surgically removed.My case has been reviewed by a team of cancer specialists or the study's lead researcher.
- Group 1: Arm 1, Radiation +/- Chemotherapy
- Group 2: Arm 2, TOS + Neck Dissection
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
To what extent is the population size participating in this research endeavor?
"Affirmative. The evidence on clinicaltrials.gov illustrates that the recruitment of participants for this trial is ongoing, with it having been initially published on June 25th 2020 and most recently updated on September 2nd 2020. A total of 68 patients are required to be recruited from a single site."
Are researchers currently recruiting volunteers for this experiment?
"According to the clinicaltrials.gov portal, this medical trial is actively looking for participants. The initial announcement was made on June 25th 2020 with a recent update published on September 2nd of the same year."
Have the regulatory bodies sanctioned Trans-Oral Surgery (TOS) + Neck Dissection?
"According to our team's evaluation, the safety of Trans-Oral Surgery (TOS) + Neck Dissection has been estimated at a 2 due to limited efficacy data being available. This is in contrast with Phase 2 trials where there are some established safety records."
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