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Cardiac Screening for Hodgkin's Lymphoma Survivors

N/A

Waitlist Available

Led By Peter Mauch, MD

Research Sponsored by Dana-Farber Cancer Institute

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Relapse-free interval of more than 1 year

Patients treated at Brigham and Women's Hospital or Dana-Farber Cancer Institute for Hodgkin's disease with mediastinal irradiation

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 3 years

Awards & highlights

Study Summary

This trial is testing whether a cardiac screening program for Hodgkin's disease survivors is possible and effective. It will also look for cardiac risk factors that could be improved with lifestyle changes or medication.

Who is the study for?

This trial is for survivors of Hodgkin's disease who were treated with chest radiation at Brigham and Women's Hospital or Dana-Farber Cancer Institute, are over 15 years old, have been in remission for more than a year, and it has been five or more years since their initial treatment.Check my eligibility

What is being tested?

The study aims to establish a heart screening program for Hodgkin's disease survivors. It involves checking the heart using echo/stress echo tests to identify potential risks and improve quality of life through lifestyle changes or medication if needed.See study design

What are the potential side effects?

Since this trial focuses on cardiac screening rather than drug intervention, there are no direct side effects from medications. However, stress during an echo test may cause temporary discomfort or anxiety.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have been free from cancer for more than a year.

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I received treatment for Hodgkin's disease with chest radiation at Brigham and Women's Hospital or Dana-Farber Cancer Institute.

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I am 15 years old or older.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 3 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~3 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

To determine the feasibility of a cardiac screening program in patients who are 5 to 10 years our from initial mediastinal irradiation for Hodgkin's disease.

Secondary outcome measures

To prospectively collect data on the prevalence of modifiable cardiac risk factors and the spectrum of cardiac structural abnormalities in this patient populations

to correlate cardiac structural abnormalities with level of fatigue.

to correlate cardiac structural abnormalities with quality of life

Trial Design

1Treatment groups

Experimental Treatment

Group I: Cardiac screeningExperimental Treatment1 Intervention

Interventions: Participants will meet with study cardiologist undergo cardiac risk factors screening undergo resting and stress echocardiogram (echo and stress echo)

0 / 3Eligibility criteria met

Find a Location

Who is running the clinical trial?

Dana-Farber Cancer InstituteLead Sponsor

1,078 Previous Clinical Trials

340,662 Total Patients Enrolled

Brigham and Women's HospitalOTHER

1,608 Previous Clinical Trials

11,469,667 Total Patients Enrolled

Peter Mauch, MDPrincipal InvestigatorDana-Farber Cancer Institute

1 Previous Clinical Trials

100 Total Patients Enrolled

Media Library

Echo/Stress Echo Clinical Trial Eligibility Overview. Trial Name: NCT00165425 — N/A

Hodgkin's Lymphoma Research Study Groups: Cardiac screening

Hodgkin's Lymphoma Clinical Trial 2023: Echo/Stress Echo Highlights & Side Effects. Trial Name: NCT00165425 — N/A

Echo/Stress Echo 2023 Treatment Timeline for Medical Study. Trial Name: NCT00165425 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this investigation recruiting participants at present?

"The clinical trial registry hosted on clinicaltrials.gov indicates that this medical study is not looking for participants at the moment. The initial posting date was February 1st, 2004 and its most recent edit transpired on March 28th, 2022. While recruitments has been discontinued here, 180 other trials are currently recruiting patients across the nation."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Cardiac Screening in Survivors of Hodgkin's Disease Treated With Mediastinal Irradiation

Andrea K. Ng, MD 2004. "Cardiac Screening in Survivors of Hodgkin's Disease Treated With Mediastinal Irradiation". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00165425.

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