Educational Media Interventions for Cancer

(ADELANTE Trial)

Recruiting at 2 trial locations

Overseen By Michelle Tuz, MPH

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Columbia University

Disqualifiers: Deafness, Blindness, Psychosis, Dementia, Metastatic, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 4

194 Participants Needed

Trial Summary

What is the purpose of this trial?

The study aims to develop educational media interventions to prepare Latinx Spanish-speaking radiation oncology patients for a course of breast or prostate cancer radiation therapy and to foster receptivity and informed decision-making around cancer clinical trial participation.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It is best to discuss this with the trial coordinators or your doctor.

What data supports the effectiveness of the treatment Audiovisual Intervention- Cancer Clinical Trials Education, Audiovisual Intervention- Radiation Therapy Education?

Research shows that audiovisual programs can help cancer patients understand their disease better, reduce anxiety, and improve communication with healthcare staff. Additionally, many patients find video-based information helpful and report learning new information from it. ^{1 2 3 4 5}

Is the educational media intervention for cancer safe for humans?

The studies reviewed did not report any safety concerns related to the use of audiovisual programs for educating cancer patients and their families. These programs were found to help reduce anxiety and improve understanding of cancer and its treatments. ^{3 5 6 7 8}

How does the Audiovisual Intervention for Cancer Education differ from other treatments?

The Audiovisual Intervention for Cancer Education is unique because it uses video-based educational materials to improve patients' understanding and confidence about cancer treatments, such as radiation therapy. Unlike traditional treatments that focus solely on medical procedures, this intervention aims to reduce anxiety and enhance communication by providing accessible information through engaging audiovisual content. ^{3 5 9 10 11}

Research Team

Lisa Kachnic, MD

Principal Investigator

Columbia University

Eligibility Criteria

This trial is for Latinx Spanish-speaking individuals with a confirmed diagnosis of non-metastatic breast or prostate cancer. They must have a Karnofsky performance status of 70 or above, indicating they are able to care for themselves. Women who can bear children need pregnancy tests as per guidelines. Participants should be planning to receive or currently undergoing curative radiation therapy and must consult using a certified interpreter.

Inclusion Criteria

My cancer has not spread beyond my prostate or breast.

I am currently being treated for breast or prostate cancer, or was recently.

I have undergone a pregnancy test as per the guidelines.

Exclusion Criteria

You have a mental illness such as psychosis or dementia.

I have received radiation therapy for areas other than my breast or prostate.

I have previously undergone radiation therapy.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

1 week

1 visit (in-person)

Radiation Therapy Education

Participants receive educational material (either written brochures or audiovisual intervention) to prepare for radiation therapy

1-4 weeks

2 visits (in-person)

Radiation Therapy

Participants undergo radiation therapy for breast or prostate cancer

4-9 weeks

Multiple visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment, including clinical trial enrollment and perceptivity

8-12 weeks

1 visit (in-person)

Long-term Follow-up

Participants' medical records are reviewed to ascertain subsequent cancer clinical trial enrollment

up to 5 years

Treatment Details

Interventions

• Audiovisual Intervention- Cancer Clinical Trials Education
• Audiovisual Intervention- Radiation Therapy Education

Trial Overview The study is testing educational media interventions designed to help Latinx patients understand radiation therapy for breast or prostate cancer and encourage informed participation in clinical trials. It includes an audiovisual education program on radiation therapy and brochures from ASTRO and NCI about cancer treatments and research studies.

Participant Groups

Group I: Audiovisual Intervention- Radiation Therapy Education Experimental Treatment 1 Intervention

Audiovisual video will be provided to the subjects as educational material.

Group II: Audiovisual Intervention- Cancer Clinical Trials Experimental Treatment 1 Intervention

Audiovisual video will be provided to the subjects as educational material.

Group III: Written Brochure- Radiation Therapy Education Active Control 1 Intervention

Written brochures will be provided to the subjects as educational material.

Group IV: Written Brochure- Cancer Clinical Trials Active Control 1 Intervention

Written brochures will be provided to the subjects as educational material.

Who Is Running the Clinical Trial?

Columbia University

Lead Sponsor

Trials

1,529

Recruited

2,832,000+

Varian

Collaborator

Trials

5

Recruited

380+

Varian Medical Systems

Industry Sponsor

Trials

63

Recruited

3,700+

Dow R. Wilson

Varian Medical Systems

Chief Executive Officer since 2012

MBA from Dartmouth's Amos Tuck School of Business, BA from Brigham Young University

Dr. Deepak Khuntia

Varian Medical Systems

Chief Medical Officer since 2020

MD from the University of Cambridge, PhD from the University of Leicester

Findings from Research

Multimedia health education significantly improved patient self-care implementation accuracy in cancer treatment, with the experimental group achieving a remarkable increase from 24.8% to 98.5%, compared to the control group's increase from 10.9% to 79.1%.

The study involved 110 patients over nearly a year, demonstrating that multimedia resources can enhance understanding and adherence to self-care practices, which is crucial for managing side effects of radiation therapy.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Effectiveness of multimedia courses in improving self-care among patients with breast cancer undergoing radiotherapy. Yang, HF., Chang, WW., Chou, YH., et al.[2023]

A study involving 92 cancer patients (26 with head and neck cancer and 66 with breast cancer) assessed the impact of a patient education video on their psychological distress, knowledge, self-efficacy, and physical symptoms, but found no significant differences between the intervention and control groups.

Despite the lack of measurable changes in outcomes, patients in the intervention group expressed high satisfaction with the video, with 90% reporting new information, suggesting that traditional study designs may not fully capture the benefits of educational materials.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Evaluating patient education materials about radiation therapy. Dunn, J., Steginga, SK., Rose, P., et al.[2022]

The evaluation of four new audiovisual programs involving 240 cancer patients and their families showed that these programs effectively increased patients' understanding of cancer and treatment.

Patients experienced significantly lower anxiety levels compared to their families, indicating that the programs not only educate but also help reduce anxiety and improve communication with healthcare staff.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Effect of audiovisual cancer programs on patients and families. Cassileth, BR., Heiberger, RM., March, V., et al.[2021]

A pilot study involving 300 cancer patients found that 78% of respondents felt that video information about their treatment would be helpful, indicating a strong preference for this format, especially among younger patients and those from ethnic groups.

As a result of the positive feedback, a 20-minute educational film about chemotherapy and radiotherapy has been created, and its impact on patient satisfaction, anxiety, and depression is being evaluated in a larger international trial.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Patients' preferences for video cassette recorded information: effect of age, sex and ethnic group. Thomas, R., Deary, A., Kaminski, E., et al.[2019]

A study involving 52 adult patients undergoing their first course of radiation therapy showed that site-specific animated videos significantly improved patient understanding and confidence regarding their treatment, with a mean increase in understanding and confidence score (UCS) from 9.36 to 11.92 after viewing the videos (P < .001).

The educational videos were particularly beneficial for patients with poor reading ability, who experienced a greater increase in their UCS, highlighting the effectiveness of visual aids in enhancing comprehension of complex medical procedures.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Site-Specific Education Using Digital Media to Improve Patient Understanding of the Radiotherapy Trajectory: An Interventional Study. Almerdhemah, H., Mulla, Z., Muamenah, HM., et al.[2022]

Patients who watched educational videos about radiation therapy reported significantly higher confidence in their knowledge of side effects (45.6% felt at least somewhat confident) compared to those who did not watch the videos (21.3%).

The videos also contributed to a decrease in anxiety for 46.8% of viewers and made 66.0% feel more comfortable attending their consultation, highlighting their effectiveness in improving patient experience.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Association Between Patient Education Videos and Knowledge of Radiation Treatment. Kumar, KA., Balazy, KE., Gutkin, PM., et al.[2021]

The AVATAR system, which allows children to watch streaming video during radiation therapy, successfully enabled 92% of pediatric patients (23 out of 25) to complete their treatment without the need for anesthesia.

This approach not only reduced the reliance on daily anesthesia but also improved the overall treatment experience for patients and their families, indicating its potential as a beneficial alternative in pediatric radiation therapy.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Initial clinical outcomes of audiovisual-assisted therapeutic ambience in radiation therapy (AVATAR). Hiniker, SM., Bush, K., Fowler, T., et al.[2018]

The implementation of a two-step audio-visual instruction system significantly improved parent satisfaction scores regarding their child's radiotherapy, with scores rising from 25.5 to 27.7 after the instruction (p < 0.01).

Anxiety levels among parents also decreased significantly after the instruction, with scores dropping from 54 to 50 (p = 0.004), indicating that this instructional method effectively alleviates anxiety related to the initiation of radiotherapy.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Changes in satisfaction and anxiety about radiotherapy for pediatric cancer by two-step audio-visual instruction. Fuji, H., Fujibuchi, T., Tanaka, H., et al.[2023]

A 23-minute educational video on radiation therapy significantly improved patients' knowledge about the treatment, with average correct responses increasing from 9.8 to 11.1 out of 21 questions (p<0.0001).

The video was effective across all sociodemographic groups, but particularly beneficial for patients with more than a high school education, highlighting the importance of educational tools in enhancing patient understanding before treatment consultations.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

The value of an educational video before consultation with a radiation oncologist. Matsuyama, RK., Lyckholm, LJ., Molisani, A., et al.[2021]

A systematic review of 315 studies on video-based interventions for cancer prevention and control found that these interventions have become more common over the past 30 years, with most studies using randomized controlled trial designs and focusing on screening and early detection, particularly for breast cancer.

The majority of studies (69%) reported success in achieving their objectives, but there is a need for future research to explore underrepresented topics like caregiving and palliative care, as well as to test new delivery methods.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Video-Based Interventions for Cancer Control: A Systematic Review. Blake, KD., Thai, C., Falisi, A., et al.[2021]

Cancer patients and their families have diverse psychological and educational needs, prompting healthcare professionals to implement a range of educational activities from one-on-one sessions to group programs across various settings.

Innovative teaching strategies, such as imagery, are being utilized to effectively address these needs, particularly during different phases of the patient's illness, highlighting the importance of tailored educational approaches.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Cancer patient education: what, where, and by whom? Crosson, K.[2007]

References

1. England pubmed.ncbi.nlm.nih.gov

Effectiveness of multimedia courses in improving self-care among patients with breast cancer undergoing radiotherapy. [2023]

2. Ireland pubmed.ncbi.nlm.nih.gov

Evaluating patient education materials about radiation therapy. [2022]

3. United States pubmed.ncbi.nlm.nih.gov

Effect of audiovisual cancer programs on patients and families. [2021]

4. England pubmed.ncbi.nlm.nih.gov

Patients' preferences for video cassette recorded information: effect of age, sex and ethnic group. [2019]

5. United States pubmed.ncbi.nlm.nih.gov

Site-Specific Education Using Digital Media to Improve Patient Understanding of the Radiotherapy Trajectory: An Interventional Study. [2022]

6. United States pubmed.ncbi.nlm.nih.gov

Association Between Patient Education Videos and Knowledge of Radiation Treatment. [2021]

7. United States pubmed.ncbi.nlm.nih.gov

Initial clinical outcomes of audiovisual-assisted therapeutic ambience in radiation therapy (AVATAR). [2018]

8. England pubmed.ncbi.nlm.nih.gov

Changes in satisfaction and anxiety about radiotherapy for pediatric cancer by two-step audio-visual instruction. [2023]

9. England pubmed.ncbi.nlm.nih.gov

The value of an educational video before consultation with a radiation oncologist. [2021]

10. United States pubmed.ncbi.nlm.nih.gov

Video-Based Interventions for Cancer Control: A Systematic Review. [2021]

11. United States pubmed.ncbi.nlm.nih.gov

Cancer patient education: what, where, and by whom? [2007]