MiraDry® for Excessive Underarm Sweating

(MiraDry Tx Trial)

Age: 18 - 65

Sex: Any

Trial Phase: Academic

Sponsor: Johns Hopkins University

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

31 Participants Needed

Trial Summary

What is the purpose of this trial?

This trial aims to evaluate the effectiveness of the miraDry® treatment system for improving the social and emotional well-being of patients with severe underarm sweating. miraDry® is a non-surgical procedure that uses heat to eliminate sweat glands in the underarms. The goal is to see if this treatment can help reduce sweating and improve quality of life compared to existing surgical options.

Research Team

Malcolm Brock, MD

Principal Investigator

Johns Hopkins University

Eligibility Criteria

This trial is for individuals aged 18-29 with severe underarm sweating, rated 3 or higher on the Hyperhidrosis Disease Severity Scale. It's open to those who've tried non-invasive treatments before. Excluded are pregnant individuals, those unable to take oral antibiotics or use antiseptic washes, patients needing supplemental oxygen, with pacemakers/electronic implants, or allergies to lidocaine/hibiclens/epinephrine.

Inclusion Criteria

I have been diagnosed with excessive sweating, mainly under my arms.

I have excessive sweating mainly under my arms.

Everyone will be evaluated using a scale to measure how severe their hyperhidrosis is.

Exclusion Criteria

I need extra oxygen.

I am unable to understand and give consent for treatment.

Patients with heart pacemakers or other electronic device implants

Treatment Details

Interventions

• MiraDry

Trial Overview The Miradry Treatment is being tested in this study. This treatment targets excessive underarm sweating (axillary hyperhidrosis). The goal is to understand how effectively it reduces sweat and improves related psychosocial issues like anxiety and social avoidance.

Participant Groups

Group I: MiraDry ® treatment Experimental Treatment 1 Intervention

MiraDry ® is the trademarked name of a non-invasive thermolytic technology which utilizes a microwave energy-based mechanism targeted for eccrine gland reduction at the dermal-fat interface. Each participant will be scheduled two MiraDry ® treatment appointments approximately three months apart.

Who Is Running the Clinical Trial?

Johns Hopkins University

Lead Sponsor

Trials

2,366

Recruited

15,160,000+