Skin Barrier Oral Supplement for Rosacea

Overseen By Milred Min

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Integrative Skin Science and Research

Must not be taking: Antibiotics, Isotretinoin, Hormonal therapies, others

Disqualifiers: Severe rosacea, Pregnancy, Smoking, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

Duration: 8 weeks

24 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

The purpose of this study is to evaluate how supplementation will alter the skin and the gut barrier and inflammation in those with rosacea.

Are You a Good Fit for This Trial?

This trial is for men and women aged 30-70 with mild to moderate rosacea and signs of inflammation (hs-CRP >= 1.0 mg/L). Participants should not have used oral antibiotics or changed hormonal therapies recently, must agree to stop certain supplements and skin treatments before the study, and cannot be pregnant, breastfeeding, or current/recent smokers.

Inclusion Criteria

Your high sensitivity C-reactive protein (hs-CRP) level is 1.0 mg/L or higher.

I am between 30 and 70 years old.

I have mild to moderate rosacea.

Exclusion Criteria

I am willing to stop taking my current supplements 1 month before joining the study.

I stopped taking L-glutamine or supplements containing it a month ago.

I am taking finasteride or dutasteride.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive an oral supplement containing L-Histidine and antioxidants to evaluate effects on skin and gut barrier function and systemic inflammation

8 weeks

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

• Skin Barrier Oral Supplement

Trial Overview The study tests an oral supplement designed to improve skin barrier function and reduce systemic inflammation in people with rosacea. It aims to see if this supplement can alter both the skin's condition and gut health positively.

How Is the Trial Designed?

Group I: Skin Barrier Oral Supplement Experimental Treatment 1 Intervention

Who Is Running the Clinical Trial?

Integrative Skin Science and Research

Lead Sponsor

Trials

33

Recruited

2,000+