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Local Anesthetic

SPG Block for Anxiety

Phase 2

Waitlist Available

Led By Anthony V Seto, MD

Research Sponsored by University of Calgary

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 10-minutes post-intervention

Awards & highlights

Study Summary

This trial tests if a 10-min SPG block can reduce anxiety at EDM festivals, compared to a placebo.

Who is the study for?

This trial is for adults over 18 who are attending an electronic dance music festival and feel anxious, rating their anxiety at least a 1 out of 10. They shouldn't have taken any anti-anxiety meds since arriving at the festival or have issues that prevent cotton applicators from being placed in their nose, like a nosebleed or allergy to lidocaine.Check my eligibility

What is being tested?

Researchers are testing if an SPG block with lidocaine can reduce anxiety compared to a placebo. Participants will get either lidocaine-soaked or saline-soaked cotton applicators in their nostrils for ten minutes to see which one better eases anxiety during the event.See study design

What are the potential side effects?

Possible side effects include discomfort or pain where the cotton tip is applied, allergic reactions if sensitive to lidocaine (though those with known allergies won't participate), and potential temporary numbness around the application area.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 10-minutes post-intervention

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~10-minutes post-intervention

This trial's timeline: 3 weeks for screening, Varies for treatment, and 10-minutes post-intervention for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Patients' self-reported anxiety scores post-intervention

Secondary outcome measures

Improvement of headache

Use of rescue-medication (i.e., oral/intravenous anti-anxiety medication)

Side effects data

From 2014 Phase 4 trial • 40 Patients • NCT01602692

40%

Nausea

10%

Vomiting

100%

80%

60%

40%

20%

Study treatment Arm

Tumescent Solution With Dilute Epinephrine

Tumescent Solution With Dilute Lidocaine and Epinephrine

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: 2% LidocaineExperimental Treatment1 Intervention

1 cotton tip applicator, pre-soaked in 2% lidocaine, inserted into each nare, and left for 10 minutes

Group II: PlaceboPlacebo Group1 Intervention

1 cotton tip applicator, pre-soaked in saline, inserted into each nare, and left for 10 minutes

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Lidocaine 2% Injectable Solution

2023

Completed Phase 3

~410

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of CalgaryLead Sponsor

792 Previous Clinical Trials

869,084 Total Patients Enrolled

6 Trials studying Anxiety

6,015 Patients Enrolled for Anxiety

Anthony V Seto, MDPrincipal InvestigatorUniversity of Calgary

1 Previous Clinical Trials

70 Total Patients Enrolled

Media Library

Lidocaine 2% Injectable Solution (Local Anesthetic) Clinical Trial Eligibility Overview. Trial Name: NCT05729503 — Phase 2

Anxiety Research Study Groups: Placebo, 2% Lidocaine

Anxiety Clinical Trial 2023: Lidocaine 2% Injectable Solution Highlights & Side Effects. Trial Name: NCT05729503 — Phase 2

Lidocaine 2% Injectable Solution (Local Anesthetic) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05729503 — Phase 2

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What potential hazards exist when utilizing 2% Lidocaine?

"With Phase 2 safety data available, our evaluation at Power gave 2% Lidocaine a score of two on the scale from one to three."

Answered by AI

What is the geographical scope of this trial?

"This medical experiment is currently taking place in 4 distinct locations. Edmonton, Toronto and Vancouver are some of the centres, with an additional 4 sites scattered around these cities. It may be beneficial to select a centre closest to your home so as to minimize travel time if you decide to participate."

Answered by AI

Is enrollment in this medical experiment still open?

"According to the clinicaltrials.gov database, this medical trial is not currrently recruiting candidates; its start date was 6th May 2023 and it's last update occured on 21st February of that same year. Nevertheless, there are currently over 600 trials actively enrolling patients at present."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Effect of SPG Block for Patients With Anxiety at Electronic Dance Music Festivals

2023. "Effect of SPG Block for Patients With Anxiety at Electronic Dance Music Festivals". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05729503.