LSFG-NAVI for Ischemic Optic Neuropathy

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Ischemic Optic Neuropathy+4 MoreLSFG-NAVI - Device
Eligibility
18 - 99
All Sexes
What conditions do you have?
Select

Study Summary

This trial looks at a new way to measure damage to the eye. Images of the retina are compared to other tests of visual function to see if this new method is effective.

Eligible Conditions
  • Ischemic Optic Neuropathy
  • Hemianopia
  • Retinal Artery Branch Blockage
  • Acute Zonal Occult Outer Retinopathy
  • Leber Hereditary Optic Neuropathy

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 0 Secondary · Reporting Duration: 1 day

1 day
Ocular Blood Flow

Trial Safety

Safety Progress

1 of 3

Trial Design

1 Treatment Group

Laser Speckle Blood Flow Group
1 of 1

Experimental Treatment

500 Total Participants · 1 Treatment Group

Primary Treatment: LSFG-NAVI · No Placebo Group · N/A

Laser Speckle Blood Flow Group
Device
Experimental Group · 1 Intervention: LSFG-NAVI · Intervention Types: Device

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 1 day

Who is running the clinical trial?

Randy KardonLead Sponsor
2 Previous Clinical Trials
620 Total Patients Enrolled
Randy H Kardon, MD, PhDPrincipal InvestigatorUniversity of Iowa Department of Ophthalmology

Eligibility Criteria

Age 18 - 99 · All Participants · 6 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
The total is to allow for exclusion of some subjects or in the event that the enrolled subject blinks too much or cannot fixate on a visual target adequately to maintain the same eye position during the short imaging interval.
Cataract or media opacity that would degrade the imaging of the retina
You have any structural defect of the eye or visual pathway that is associated with optic neuropathy.
You have focal or diffuse outer photoreceptor loss of function.

Who else is applying?

What state do they live in?
Iowa100.0%
How old are they?
18 - 65100.0%
What site did they apply to?
University of Iowa Department of Ophthalmology100.0%
What portion of applicants met pre-screening criteria?
Met criteria100.0%