Perineal Wipe for UTI
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests whether using a cleansing wipe before collecting a urine sample can reduce contamination in women with urinary tract infection (UTI) symptoms. Participants will either use a perineal wipe before providing their sample or give their sample without a wipe. Women who might be suitable for this trial are those experiencing symptoms such as frequent or urgent need to urinate, pain during urination, or cloudy or foul-smelling urine. As an unphased trial, this study offers participants the chance to contribute to research that could enhance diagnostic accuracy for UTIs.
Do I need to stop my current medications to join the trial?
The trial does not specify if you need to stop taking your current medications, but you cannot participate if you are already on antibiotics or take daily antibiotic prophylaxis.
What prior data suggests that this perineal wipe is safe for use in urine sample collection?
Research has shown that using a special wipe, called a perineal wipe, before collecting a midstream urine sample can help reduce contamination. A perineal wipe resembles a sterile baby wipe and is cleaner than toilet paper.
Specific safety information for perineal wipes in this trial is unavailable, but they are generally safe for hygiene use. Some materials in these wipes might cause mild irritation if they contact the eyes, though this is unlikely with correct use.
Overall, perineal wipes are well-tolerated and commonly used for personal hygiene without major safety concerns.12345Why are researchers excited about this trial?
Researchers are excited about the trial of the perineal wipe for urinary tract infections (UTIs) because it introduces a simple, non-invasive method to potentially reduce contamination in urine samples. Unlike standard care, which typically involves oral antibiotics to treat UTIs, this approach focuses on improving the accuracy of initial urine cultures, potentially leading to more accurate diagnoses and targeted treatments. By ensuring cleaner sample collection, this method could help avoid unnecessary antibiotic use and enhance the precision of UTI management.
What evidence suggests that using a perineal wipe is effective for reducing contamination in urine samples for UTIs?
This trial will compare the use of a Perineal Wipe with no wipe before collecting a midstream urine sample. Research has shown that using a special wipe can reduce contamination, leading to more accurate test results. One study found that cleaning the area with a chlorhexidine solution lowered the risk of urinary tract infections (UTIs) linked to catheters. Although specific evidence about wipes remains limited, early findings suggest that better hygiene in this area might reduce UTI risks. In summary, improved cleaning practices could enhance sample accuracy and lower infection rates.36789
Who Is on the Research Team?
Joanna A Orzel
Principal Investigator
University of Iowa
Are You a Good Fit for This Trial?
This trial is for adult female patients over 18 who are experiencing symptoms of a urinary tract infection (UTI), such as urgency, frequency, pain, fever, or cloudy/malodorous urine. They must be visiting the urology clinic at IRL or 3RC.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants are randomized to either use a perineal cleansing wipe or not before collecting a mid-stream clean catch urine sample
Follow-up
Participants are monitored for the rate of contamination in urine samples
What Are the Treatments Tested in This Trial?
Interventions
- Perineal Wipe
Trial Overview
The study is testing if using a perineal cleansing wipe before giving a midstream urine sample can reduce contamination rates in samples from women with symptomatic UTIs. It's a randomized control trial where some will use wipes and others won't.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
Patient will use wipe before collecting mid-stream clean catch culture
Patient will not use wipe before collecting mid-stream clean catch culture
Find a Clinic Near You
Who Is Running the Clinical Trial?
Joanna A. Orzel
Lead Sponsor
Citations
Antibacterial perineal washing for prevention of recurrent ...
These results suggest that hexachlorophene perineal washing was not effective in preventing UTI in females.
Antibacterial perineal washing for prevention of recurrent ...
These results suggest that hexachlorophene perineal washing was not effective in preventing UTI in females. Recommended articles. References (6). R.R. Landes ...
Post-Toilet Wiping Style Is Associated With the Risk of ...
This post-toilet wiping habit was suggested to be a potential risk of UTI in women, especially in middle-aged subgroups, and may be better to be changed to ...
4.
eu-openscience.europeanurology.com
eu-openscience.europeanurology.com/article/S2666-1683(25)01418-1/fulltextRisk of Urinary Tract Infection with Perineal Urethrostomy ...
Conclusions and clinical implications ... PU does not increase the risk of UTI in comparison to urethroplasty for complex urethral strictures.
Comparison of the Effect of Perineal Care with Normal ...
The results showed that washing the perineal area every 12 hours with 2% chlorhexidine solution compared to normal saline reduces the incidence of CAUTIs in ...
Recurrent Urinary Tract Infections - StatPearls - NCBI Bookshelf
However, the patient must wipe once, or they may add more bacteria to the urethral area. Sterile baby wipes are cleaner than toilet paper and can be carried in ...
FAQs: Urinary Tract Infection (UTI) Events | NHSN
Only catheter-associated UTI data (both ABUTI and SUTI) are shared with CMS. Keep in mind that ABUTI may occur in patients with or without an indwelling urinary ...
Antibacterial perineal wash as prophylaxis for recurrent ...
Potential health effects listed on the Material Safety Data Sheet by GOJO Industries of the perineal wash include: eye irritation if applied to ...
Recurrent Uncomplicated Urinary Tract Infections in Women
This document seeks to establish guidance for the evaluation and management of patients with rUTIs to prevent inappropriate use of antibiotics.
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.