Perineal Wipe for UTI
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests whether using a cleansing wipe before collecting a urine sample can reduce contamination in women with urinary tract infection (UTI) symptoms. Participants will either use a perineal wipe before providing their sample or give their sample without a wipe. Women who might be suitable for this trial are those experiencing symptoms such as frequent or urgent need to urinate, pain during urination, or cloudy or foul-smelling urine. As an unphased trial, this study offers participants the chance to contribute to research that could enhance diagnostic accuracy for UTIs.
Do I need to stop my current medications to join the trial?
The trial does not specify if you need to stop taking your current medications, but you cannot participate if you are already on antibiotics or take daily antibiotic prophylaxis.
What prior data suggests that this perineal wipe is safe for use in urine sample collection?
Research has shown that using a special wipe, called a perineal wipe, before collecting a midstream urine sample can help reduce contamination. A perineal wipe resembles a sterile baby wipe and is cleaner than toilet paper.
Specific safety information for perineal wipes in this trial is unavailable, but they are generally safe for hygiene use. Some materials in these wipes might cause mild irritation if they contact the eyes, though this is unlikely with correct use.
Overall, perineal wipes are well-tolerated and commonly used for personal hygiene without major safety concerns.12345Why are researchers excited about this trial?
Researchers are excited about the trial of the perineal wipe for urinary tract infections (UTIs) because it introduces a simple, non-invasive method to potentially reduce contamination in urine samples. Unlike standard care, which typically involves oral antibiotics to treat UTIs, this approach focuses on improving the accuracy of initial urine cultures, potentially leading to more accurate diagnoses and targeted treatments. By ensuring cleaner sample collection, this method could help avoid unnecessary antibiotic use and enhance the precision of UTI management.
What evidence suggests that using a perineal wipe is effective for reducing contamination in urine samples for UTIs?
This trial will compare the use of a Perineal Wipe with no wipe before collecting a midstream urine sample. Research has shown that using a special wipe can reduce contamination, leading to more accurate test results. One study found that cleaning the area with a chlorhexidine solution lowered the risk of urinary tract infections (UTIs) linked to catheters. Although specific evidence about wipes remains limited, early findings suggest that better hygiene in this area might reduce UTI risks. In summary, improved cleaning practices could enhance sample accuracy and lower infection rates.36789
Who Is on the Research Team?
Joanna A Orzel
Principal Investigator
University of Iowa
Are You a Good Fit for This Trial?
This trial is for adult female patients over 18 who are experiencing symptoms of a urinary tract infection (UTI), such as urgency, frequency, pain, fever, or cloudy/malodorous urine. They must be visiting the urology clinic at IRL or 3RC.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants are randomized to either use a perineal cleansing wipe or not before collecting a mid-stream clean catch urine sample
Follow-up
Participants are monitored for the rate of contamination in urine samples
What Are the Treatments Tested in This Trial?
Interventions
- Perineal Wipe
Find a Clinic Near You
Who Is Running the Clinical Trial?
Joanna A. Orzel
Lead Sponsor