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What is Thiothixene
ThiothixeneThe Generic name of this drug
Treatment SummaryThioxanthine is an antipsychotic medication used to treat mental disorders. It works in a similar way to other antipsychotic medicines known as phenothiazines.
Navaneis the brand name
Thiothixene Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Navane
Thiothixene
1967
50
Approved as Treatment by the FDA
Thiothixene, also known as Navane, is approved by the FDA for 1 uses which include Schizophrenia .Schizophrenia
Helps manage Schizophrenia
Effectiveness
How Thiothixene Affects PatientsThiothixene is an older type of antipsychotic medication that belongs to the thioxanthene class. It is similar to piperazine phenothiazines and different from aliphatic phenothiazines. It was commonly used to treat schizophrenia in the past, but is less commonly used today compared to newer medications such as risperidone.
How Thiothixene works in the bodyThiothixene works as a blocker on certain receptors in the brain, such as dopamine, serotonin, histamine, and acetylcholine. It has different effects on productive and unproductive symptoms, including anti-anxiety, anti-depressive, anti-aggressive, and anti-nausea properties. It can also lead to weight gain, lowered blood pressure, sedation, and difficulty ejaculating. Thiothixene can lower blood pressure, cause vertigo, sedation, hypersalivation, incontinence, and sexual dysfunction. It also causes anticholinergic effects like dry mouth, blurred vision
When to interrupt dosage
The proposed dosage of Thiothixene is contingent upon the established affliction. The dose changes as per the mode of distribution (e.g. Capsule or Capsule - Oral) featured in the table beneath.Condition
Dosage
Administration
Schizophrenia
, 1.0 mg, 2.0 mg, 5.0 mg, 10.0 mg, 20.0 mg, 5.0 mg/mL
, Capsule, Oral, Capsule - Oral, Tablet - Oral, Tablet, Solution, concentrate, Solution, concentrate - Oral
Warnings
Thiothixene ContraindicationsCondition
Risk Level
Notes
Coma
Do Not Combine
Shock
Do Not Combine
Disease
Do Not Combine
Mental Depression
Do Not Combine
Common Thiothixene Drug Interactions
Drug Name
Risk Level
Description
Amisulpride
Major
Thiothixene may increase the antipsychotic activities of Amisulpride.
Azelastine
Major
Thiothixene may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Deutetrabenazine
Major
The risk or severity of adverse effects can be increased when Thiothixene is combined with Deutetrabenazine.
Ethanol
Major
Thiothixene may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Hydroxyzine
Major
The risk or severity of QTc prolongation can be increased when Thiothixene is combined with Hydroxyzine.
Thiothixene Toxicity & Overdose RiskOverdosing on Clonazepam can lead to symptoms such as confusion, difficulty swallowing, dizziness, drowsiness, head tilting, low blood pressure, muscle twitching, stiff muscles, excessive drooling, trembling, trouble walking, and weakness.
Thiothixene Novel Uses: Which Conditions Have a Clinical Trial Featuring Thiothixene?
170 active clinical trials are presently evaluating Thiothixene as a potential intervention for Schizophrenia.Condition
Clinical Trials
Trial Phases
Schizophrenia
105 Actively Recruiting
Phase 3, Not Applicable, Early Phase 1, Phase 4, Phase 2, Phase 1
Thiothixene Reviews: What are patients saying about Thiothixene?
5Patient Review
10/26/2012 I didn't see much benefit from this medication.
5Patient Review
10/11/2008 this was the first drug I tried that didn't give me awful side effects like twitches and tremors.
5Patient Review
2/16/2014 My sister was taking this in the 5 mg capsules and it was working really well for her. She's been trying different drugs to treat her disorder for awhile now and this is by far the best one she's found. But now they're telling her it's not going to be available anymore and she's really worried that she won't be able to find an effective replacement.
5Patient Review
1/13/2016 Thiothixene has been a godsend for my schizophrenia. It's helped me to deal with the distortions in my mind much more effectively, and I'm extremely grateful for that.
4.7Patient Review
4/3/2008Patient Q&A Section about thiothixene
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is the drug thiothixene used for?
"This medication is used to treat schizophrenia and should not be used to treat behavioral problems in older adults who have dementia. It is only available with a doctor's prescription."
Answered by AI
Is thiothixene a sedative?
"Use Caution/Monitor.
Brompheniramine and buprenorphine both increase sedation. Use caution when prescribing them together and monitor patients for excessive sedation."
Answered by AI
What is the brand name for thiothixene?
"Thiothixene is a prescription antipsychotic medication used to treat the symptoms of schizophrenia. It may be used alone or with other medications."
Answered by AI
What are the side effects of thiothixene?
"The following are symptoms of dizziness: lightheadedness, feeling unsteady, having trouble keeping your balance, blurred vision, dry mouth, excess saliva, stuffed nose, nausea, vomiting, and constipation."
Answered by AI
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