Testosterone Enanthate

Hypogonadism, Hypogonadism, Hypogonadism

Treatment

3 Active Studies for Testosterone Enanthate

Treatment for

Hypogonadism

What is Testosterone Enanthate

Testosterone enanthate

The Generic name of this drug

Treatment Summary

Testosterone enanthate is a form of testosterone that is injected into the body and released slowly over time. It was first approved for medical use in 1953 and is now commonly used to treat low testosterone levels. In 2017, 6.5 million prescriptions were filled for testosterone therapy, most of them being injectable or topical forms of the hormone. In 2018, the FDA approved Xyosted, a once-weekly testosterone enanthate product designed to be self-administered with a single dose, disposable autoinjector. This new formulation removes the need for frequent visits to the clinic for injections.

Delatestryl

is the brand name

image of different drug pills on a surface

Testosterone Enanthate Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Delatestryl

Testosterone enanthate

1953

Effectiveness

How Testosterone Enanthate Affects Patients

Taking testosterone enanthate can raise the amount of testosterone in the body up to four times the normal level within 24 hours. After this initial increase, the levels of testosterone stay higher than normal for 3-5 days. Taking testosterone enanthate regularly can suppress levels of dihydrotestosterone, PSA, HDL and FSH, and also slightly raise the level of estradiol in the body. The suppression of dihydrotestosterone and FSH can last up to 14 days after stopping treatment. There is no effect on mood or sexual activity from taking testosterone enanthate.

How Testosterone Enanthate works in the body

Testosterone affects the body in two ways. It can either bind to the androgen receptor directly, or it can be converted to DHT, which binds more strongly to the receptor. This binding triggers a reaction in the cell nucleus, which affects certain genes and causes physical changes, like hair growth and increased muscle mass. Testosterone is also responsible for the growth and development of male organs and body parts. Low levels of testosterone can lead to male hypogonadism, which is caused either by problems with the gonads or with the hypothalamus or pituitary gland.

When to interrupt dosage

The measure of Testosterone Enanthate is contingent upon the recognized affliction, including Hypogonadism, Hypogonadism and Hypergonadotropic Hypogonadism. The amount additionally deviates as indicated by the technique of delivery (e.g. Liquid - Intramuscular or Injection, solution) specified in the table below.

Condition

Dosage

Administration

Hypogonadism

, 200.0 mg/mL, 1000.0 mg/mL, 750.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL

, Injection, solution, Injection, solution - Intramuscular, Solution, Solution - Intramuscular, Intramuscular, Injection - Intramuscular, Injection, Subcutaneous, Injection - Subcutaneous, Liquid - Intramuscular, Liquid

Hypogonadism

, 200.0 mg/mL, 1000.0 mg/mL, 750.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL

Hypogonadism

, 200.0 mg/mL, 1000.0 mg/mL, 750.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL

Warnings

Testosterone Enanthate Contraindications

Condition

Risk Level

Notes

Hypogonadism

Do Not Combine

Breast Cancer

Do Not Combine

There are 20 known major drug interactions with Testosterone Enanthate.

Common Testosterone Enanthate Drug Interactions

Drug Name

Risk Level

Description

Astemizole

Major

The metabolism of Astemizole can be decreased when combined with Testosterone enanthate.

Axitinib

Major

The metabolism of Axitinib can be decreased when combined with Testosterone enanthate.

Brigatinib

Major

The metabolism of Brigatinib can be decreased when combined with Testosterone enanthate.

Cabazitaxel

Major

The metabolism of Cabazitaxel can be decreased when combined with Testosterone enanthate.

Capmatinib

Major

The serum concentration of Capmatinib can be decreased when it is combined with Testosterone enanthate.

Testosterone Enanthate Toxicity & Overdose Risk

Taking testosterone enanthate could increase the risk of blood clots and create more tumors. It is not safe for pregnant women or children and can cause fertility issues in men. Using testosterone enanthate can also cause prostate problems in older adults.

image of a doctor in a lab doing drug, clinical research

Testosterone Enanthate Novel Uses: Which Conditions Have a Clinical Trial Featuring Testosterone Enanthate?

Presently, 7 trials are assessing the potential of Testosterone Enanthate to provide relief from Hypogonadism, Eunuchoidism and Hypergonadotropic Hypogonadism.

Condition

Clinical Trials

Trial Phases

Hypogonadism

0 Actively Recruiting

Hypogonadism

0 Actively Recruiting

Hypogonadism

3 Actively Recruiting

Phase 2

Testosterone Enanthate Reviews: What are patients saying about Testosterone Enanthate?

Patient Review

9/19/2009

Testosterone Enanthate for Rare X Chromosome Abnormality - Klinefelter Syndrome

I was diagnosed with Klienfelters Syndrome about 6 years ago. I tried using the testerone replacement patch and the gel, but saw little effect. However, after two weeks of using the injection, I have seen a big difference in many areas of my daily activities.

Patient Review

12/22/2008

Testosterone Enanthate for Deficiency of Luteinizing Hormone-Releasing Hormone

I'm 45 and using two cc's per week, and I feel incredible! Not only have I maintained my hairline, but my libido is through the roof. I was also taking Ambien CR to help me sleep, but within three weeks of starting this treatment, I was sleeping like a baby without it! Overall, I've just been feeling really good lately.

Patient Review

11/21/2014

Testosterone Enanthate for Pituitary Hormone Deficiency

I've been on this treatment for two years and have seen some great results. I've lost 80lbs and my stamina and energy has increased a lot. The only side effect I've experienced is acne, but that's not always the case.

Patient Review

8/3/2011

Testosterone Enanthate for Deficiency of Luteinizing Hormone-Releasing Hormone

I would recommend this treatment to anyone.

4.7

Patient Review

2/20/2014

Testosterone Enanthate for Deficiency of a Substance that Promotes Masculinization

I was diagnosed with low testosterone and given a prescription for 100 mg per week. Prior to the shots, I was very moody, depressed, gaining weight, and really just tired all the time. I had quit working out after over 20 years of regular visits to the gym. 3 years into treatment, I'm now back in the gym and my mood has improved significantly. Additionally, my erectile dysfunction has resolved itself; something that was a big issue for me before starting this medication regimen. All in all, it's worked well for me.

Patient Review

2/14/2011

Testosterone Enanthate for Rare X Chromosome Abnormality - Klinefelter Syndrome

I found this treatment to be much better than gels or patches that I've tried in the past. The only downside is that it can cause too much hemoglobin buildup, requiring frequent blood tests.

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Patient Q&A Section about testosterone enanthate

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Can I build muscle with testosterone enanthate?

"Testosterone enanthate has been shown to increase strength within 6-12 weeks of administration, but it is unclear if the benefits are evident in less than 6 weeks."

Answered by AI

What is testosterone enanthate used for?

"Testosterone enanthate is a long-acting form of testosterone, so it lasts for several weeks in the body.

Testosterone enanthate is an injectable form of testosterone used to treat low testosterone in males, as well as breast cancer that has spread to other parts of the body in females. Testosterone enanthate is a long-acting form of testosterone, so it is effective for several weeks."

Answered by AI

What is difference between testosterone cypionate and enanthate?

"The chemical structure of testosterone cypionate and testosterone enanthate are very similar, with the exception of an additional carbon atom in the former that makes its half life slightly longer at 8 days, as opposed to the latter's 7."

Answered by AI

What are the side effects of testosterone enanthate?

"The following side effects may occur: nausea, vomiting, headache, skin color changes, increased/decreased sexual interest, oily skin, hair loss, acne, pain and redness at the injection site."

Answered by AI