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What is Tenormin
AtenololThe Generic name of this drug
Treatment SummaryAtenolol is a type of medication used to treat various heart conditions. It was invented in 1958 by Scottish pharmacologist Sir James Black, who won the Nobel Prize for his work. Atenolol is usually prescribed for high blood pressure, heart attack, arrhythmias, and heart failure. However, studies have suggested that atenolol may not reduce mortality or cardiovascular disease in people with hypertension, and the risk of stroke may depend on the age of the patient. Therefore, atenolol should be used based on more than just hypertension.
Tenorminis the brand name
Tenormin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Tenormin
Atenolol
1990
432
Approved as Treatment by the FDA
Atenolol, otherwise called Tenormin, is approved by the FDA for 6 uses like Hemodynamically Stable and Slow Heart Rate .Hemodynamically Stable
Slow Heart Rate
Heart Attack
Hypertensive disease
Used to treat Refractory Hypertension in combination with Chlorthalidone
Hypertensive disease
Helps manage High Blood Pressure (Hypertension)
Systolic Blood Pressure >100 mmHg
Effectiveness
How Tenormin Affects PatientsAtenolol is a drug that can help regulate the heart. It works by blocking certain hormones and nerves that control the heart rate, electrical conductivity, and contractility. This reduces the amount of work the heart needs to do, which can reduce the risk of angina or chest pain. It also helps to control the rate of electrical signals in the heart, which can help with arrhythmia (irregular heartbeat). Atenolol can also help lower blood pressure, though it is less effective than other beta blocker drugs. It may cause fatigue, depression, or sleep disturbances like nightmares or insomnia. It can also cause
How Tenormin works in the bodyAtenolol is a type of drug that only affects certain parts of the body, called a cardioselective beta-blocker. It works by blocking the activity of special receptors in the heart and lungs called beta-1 receptors. When these receptors are blocked, the signals sent to the heart and lungs that cause them to work harder are stopped. This can slow down the heart rate and relax the muscles in the lungs, making it easier to breathe. In the heart, atenolol stops certain proteins from increasing the amount of calcium in the cells. This helps reduce the amount of contractions in the heart and keeps
When to interrupt dosage
The quantity of Tenormin is contingent upon the identified condition, including Atrial Fibrillation, Migraine and Hypertensive disease. The measure of dosage shifts as per the technique of delivery (e.g. Tablet - Oral or Tablet) specified in the table beneath.Condition
Dosage
Administration
Heart Attack
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Thyrotoxicosis
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Syndrome
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Systolic Blood Pressure >100 mmHg
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Hypertensive disease
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Migraine
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Tachycardia, Ventricular
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Tachycardia, Ventricular
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Coronary Artery Atherosclerosis
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Chest Pain
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
prophylaxis of migraine headaches
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Hypertensive disease
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Secondary prevention Myocardial infarction
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Hemodynamically Stable
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Atrial Fibrillation
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Slow Heart Rate
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Congestive Heart Failure
, 50.0 mg, 100.0 mg, 25.0 mg, 50.0 mg/mg, 5.0 mg/mg, 2.5 mg/mg, 0.5 mg/mL
, Oral, Tablet, Tablet - Oral, Buccal; Oral; Sublingual; Transmucosal, Tablet - Buccal; Oral; Sublingual; Transmucosal, Intravenous, Injection, solution, Injection, solution - Intravenous
Warnings
Tenormin ContraindicationsCondition
Risk Level
Notes
Heart Block
Do Not Combine
Shock, Cardiogenic
Do Not Combine
Sinus Bradycardia
Do Not Combine
overt cardiac failure
Do Not Combine
Common Tenormin Drug Interactions
Drug Name
Risk Level
Description
4-Bromo-2,5-dimethoxyphenethylamine
Major
The therapeutic efficacy of 4-Bromo-2,5-dimethoxyphenethylamine can be decreased when used in combination with Atenolol.
4-Methoxyamphetamine
Major
The therapeutic efficacy of 4-Methoxyamphetamine can be decreased when used in combination with Atenolol.
Abediterol
Major
The therapeutic efficacy of Abediterol can be decreased when used in combination with Atenolol.
Adrafinil
Major
The therapeutic efficacy of Adrafinil can be decreased when used in combination with Atenolol.
Agrostis gigantea pollen
Major
The risk of a hypersensitivity reaction to Agrostis gigantea pollen is increased when it is combined with Atenolol.
Tenormin Toxicity & Overdose RiskThe toxic dose of atenolol in mice is 2g/kg when taken orally, 57mg/kg when taken intravenously, 134mg/kg when injected into the body, and 400mg/kg when given subcutaneously. In rats the toxic dose is 2g/kg when taken orally and 77mg/kg when taken intravenously. Rabbits have a toxic dose of 50mg/kg when taken intravenously. Studies in rats and mice showed no carcinogenic effects when the animals were given 300mg/kg per day (150 times the maximum recommended human dose) for 18-24 months
Tenormin Novel Uses: Which Conditions Have a Clinical Trial Featuring Tenormin?
626 active studies are presently investigating the potential of Tenormin in managing Atrial Fibrillation, Coronary Artery Atherosclerosis and Ventricular Tachycardia.Condition
Clinical Trials
Trial Phases
prophylaxis of migraine headaches
0 Actively Recruiting
Secondary prevention Myocardial infarction
0 Actively Recruiting
Thyrotoxicosis
0 Actively Recruiting
Tachycardia, Ventricular
0 Actively Recruiting
Migraine
52 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3, Phase 4, Early Phase 1
Atrial Fibrillation
146 Actively Recruiting
Not Applicable, Phase 2, Phase 4, Phase 1, Phase 3, Early Phase 1
Heart Attack
52 Actively Recruiting
Phase 4, Phase 2, Phase 3, Not Applicable, Phase 1, Early Phase 1
Systolic Blood Pressure >100 mmHg
0 Actively Recruiting
Coronary Artery Atherosclerosis
2 Actively Recruiting
Not Applicable, Phase 4
Slow Heart Rate
7 Actively Recruiting
Phase 4, Not Applicable
Hemodynamically Stable
0 Actively Recruiting
Syndrome
3 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Hypertensive disease
0 Actively Recruiting
Congestive Heart Failure
311 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 1, Early Phase 1, Phase 4
Chest Pain
6 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 4
Tachycardia, Ventricular
0 Actively Recruiting
Hypertensive disease
19 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Tenormin Reviews: What are patients saying about Tenormin?
5Patient Review
1/24/2012 I've been taking Tenormin for a while now and it does help to keep my blood pressure stable. However, I have developed an annoying cough that I haven't been able to shake. From what I understand, this is a common side-effect of the medication. Has anyone else experienced something similar?
5Patient Review
3/25/2014 I started with a 100 mg dose, but my blood pressure went down to about 90/65. The doctor reduced my dosage to 50 mg a day and it has worked well for my blood pressure. My heart rate is high (120 to 90 bpm) and it did not affect that so I'm going to ask for a beta blocker like Sectral.
5Patient Review
10/18/2011 I've been on this medication for a long time, and it's no longer keeping my blood pressure down. I'll have to add other medications to it now. I also wonder if it's good for diabetics given that it can cause kidney problems.
5Patient Review
1/24/2013 This treatment is always effective and helpful.
5Patient Review
11/15/2012 After taking the 12.5 mg dose, I felt lightheaded and dizzy after two hours.
5Patient Review
2/24/2012 I've been on this medication for a few years now and it's done wonders for managing my PVCs. I started at a lower dose and gradually increased as needed. I experienced some fatigue and breathlessness, but it was worth it to get my BP under control.
4.7Patient Review
4/27/2016 I've been taking Atenolol 50mg for my hypertension and it's been working great. I'm 39 years old and have been taking this medication for more than two years now. I used to take it at night so I didn't experience any fatigue during the day.
4.7Patient Review
3/15/20114.7Patient Review
2/18/2015 I've been taking this medication for nearly two years now, in conjunction with amlodipino and enalapril. So far so good!
4.3Patient Review
8/10/20114Patient Review
7/3/2014 I have noticed changes in my husband's personality since he started taking Tenormin. Has anyone else experienced this side effect?
3.7Patient Review
1/17/2012 I've been on this medication for over 15 years, and in the last six months my blood pressure has not been where it should be. My doctor added Lisinopril 20 mg once a day, but after reading these reviews I realize that I have a lot of symptoms that I thought were due to getting older. These include thinning hair, fatigue, weight gain, no libido, tiredness all the time, depression, etc.
3.7Patient Review
5/18/2012 I've been taking Tenormin 50mg for two decades with good results. I haven't experienced any side effects, which is great. My blood pressure has stayed around 128/78.
3.7Patient Review
9/17/2011 I was on 50mg for many years. B/P good & HB slow 50-60. 3 yrs ago reduced to 25mg. Still about the same. Recently told to cut pill in half & take every 12 hrs. Still about the same. Experience some shortness of breath and fatigue, which I can live with as I am still able to be quite active. Also caused ED; thankfully viagra exists
3.7Patient Review
9/17/2011 I took Atenolol for one year and it did lower my blood pressure; however, I started losing hair mass after just three months on the medication. This was a huge downside for me, and something to keep in mind if you're considering this treatment option.
3.3Patient Review
5/1/2012 I was feeling better until Procardia was added to my treatment.
3Patient Review
6/18/2012 I took this drug for many years and saw some great benefits, like quitting smoking and drinking, and losing weight. Recently I complained of shortness of breath to my doctor, who then weaned me off the medication. As a result, I no longer have shortness of breath; in fact, a number of other issues I had before - like GERD and fatigue - got better. I would definitely recommend making lifestyle changes if you're able.
2.7Patient Review
2/21/2018 I've been taking this for four days now and I am feeling very strange. I can't sleep, I'm constantly crying, and I feel really creepy. Not sure if I can handle two more weeks of this.
2.7Patient Review
5/5/2011Patient Q&A Section about tenormin
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What are the side effects of Tenormin?
"The following are symptoms of the flu:
Dizziness
Lightheadedness
Tired feeling
Nausea
Slow heart rate
Decreased sex drive
Impotence"
Answered by AI
When should I take Tenormin?
"To take atenolol, you will typically take it once or twice a day. Your doctor may tell you to take your first dose before going to bed because it can make you feel dizzy. If you do not feel dizzy after the first dose, you can take the medicine in the morning."
Answered by AI
Is Tenormin a good drug?
"Atenolol (Tenormin) can help to relieve chest pain and angina. It may also reduce the risk of death if taken after a heart attack. Although it can be used to treat high blood pressure, it is not the preferred option and is usually only used if other medications have not been effective."
Answered by AI
What is Tenormin tablets used for?
"Atenolol is used to treat high blood pressure, either on its own or with other medications. By lowering high blood pressure, it can help prevent strokes, heart attacks and kidney problems. It is also used to treat chest pain (angina) and improve survival rates after a heart attack."
Answered by AI