Taztia Xt

Angina Pectoris, Variant, Atrial Fibrillation, Proteinuria + 11 more
Treatment
4 FDA approvals
20 Active Studies for Taztia Xt

What is Taztia Xt

DiltiazemThe Generic name of this drug
Treatment SummaryDiltiazem is a medication used to treat high blood pressure, heart conditions, and chest pain. It is a type of calcium channel blocker that works by preventing calcium from entering the cells of the heart and blood vessels, causing them to relax and widening the vessels. Diltiazem is available in both oral and intravenous forms and can be taken long-term to treat chronic conditions. It is most commonly used to treat hypertension, chronic stable angina, and atrial fibrillation or flutter. It may also be used off-label to treat anal fissures, migraine prevention, pulmonary hypertension, and muscle cramps
Cardizemis the brand name
Taztia Xt Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Cardizem
Diltiazem
1982
656

Approved as Treatment by the FDA

Diltiazem, commonly known as Cardizem, is approved by the FDA for 4 uses which include Chronic Stable Angina Pectoris and Hypertensive disease .
Chronic Stable Angina Pectoris
Helps manage Chronic Stable Angina Pectoris
Hypertensive disease
Helps manage High Blood Pressure (Hypertension)
Coronary Artery Vasospasm
Helps manage Coronary Artery Vasospasm
Anginal Pain
Helps manage Anginal Pain

Effectiveness

How Taztia Xt Affects PatientsDiltiazem works by relaxing the blood vessels and reducing blood pressure. Lowering blood pressure helps to reduce the risk of stroke, heart attack, and other cardiovascular issues. Diltiazem inhibits the flow of calcium into cells, leading to a decrease in heart rate and force of heartbeats. This can help to slow down an abnormally fast heart rate. In people with high blood pressure, taking diltiazem can lower diastolic blood pressure by 1.9, 5.4, 6.1, or 8.6 mmHg depending on the dose taken. In those with angina, diltiaz
How Taztia Xt works in the bodyDiltiazem works by blocking slow calcium channels in the heart muscle, which helps reduce calcium levels. This results in the relaxation of smooth muscle and blood vessels, increasing oxygen supply to the heart, lowering blood pressure and afterload, and reducing the heart rate. This decreased stress on the heart can help those with chronic stable angina exercise with greater tolerance.

When to interrupt dosage

The instructed dosage of Taztia Xt is contingent upon the diagnosed condition, for example prophylaxis of migraine headaches, Fissure;Anal and Anginal Pain. The quantity of dosage is determined by the manner of administration, as indicated in the table beneath.
Condition
Dosage
Administration
Coronary Artery Vasospasm
, 120.0 mg, 180.0 mg, 240.0 mg, 300.0 mg, 360.0 mg, 420.0 mg, 100.0 mg, 60.0 mg, 90.0 mg, 30.0 mg, 5.0 mg/mL, 1.0 mg/mL, 0.83 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Powder, for solution - Intravenous, Intravenous, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Injection, Injection - Intravenous, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Tablet, coated, Tablet, coated - Oral, Solution, Solution - Intravenous, Liquid, Liquid - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous
Hypertensive disease
, 120.0 mg, 180.0 mg, 240.0 mg, 300.0 mg, 360.0 mg, 420.0 mg, 100.0 mg, 60.0 mg, 90.0 mg, 30.0 mg, 5.0 mg/mL, 1.0 mg/mL, 0.83 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Powder, for solution - Intravenous, Intravenous, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Injection, Injection - Intravenous, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Tablet, coated, Tablet, coated - Oral, Solution, Solution - Intravenous, Liquid, Liquid - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous
Angina Pectoris, Variant
, 120.0 mg, 180.0 mg, 240.0 mg, 300.0 mg, 360.0 mg, 420.0 mg, 100.0 mg, 60.0 mg, 90.0 mg, 30.0 mg, 5.0 mg/mL, 1.0 mg/mL, 0.83 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Powder, for solution - Intravenous, Intravenous, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Injection, Injection - Intravenous, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Tablet, coated, Tablet, coated - Oral, Solution, Solution - Intravenous, Liquid, Liquid - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous
Atrial Fibrillation
, 120.0 mg, 180.0 mg, 240.0 mg, 300.0 mg, 360.0 mg, 420.0 mg, 100.0 mg, 60.0 mg, 90.0 mg, 30.0 mg, 5.0 mg/mL, 1.0 mg/mL, 0.83 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Powder, for solution - Intravenous, Intravenous, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Injection, Injection - Intravenous, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Tablet, coated, Tablet, coated - Oral, Solution, Solution - Intravenous, Liquid, Liquid - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous
Pulmonary Hypertension
, 120.0 mg, 180.0 mg, 240.0 mg, 300.0 mg, 360.0 mg, 420.0 mg, 100.0 mg, 60.0 mg, 90.0 mg, 30.0 mg, 5.0 mg/mL, 1.0 mg/mL, 0.83 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Powder, for solution - Intravenous, Intravenous, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Injection, Injection - Intravenous, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Tablet, coated, Tablet, coated - Oral, Solution, Solution - Intravenous, Liquid, Liquid - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous
Paroxysmal Supraventricular Tachycardia (PSVT)
, 120.0 mg, 180.0 mg, 240.0 mg, 300.0 mg, 360.0 mg, 420.0 mg, 100.0 mg, 60.0 mg, 90.0 mg, 30.0 mg, 5.0 mg/mL, 1.0 mg/mL, 0.83 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Powder, for solution - Intravenous, Intravenous, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Injection, Injection - Intravenous, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Tablet, coated, Tablet, coated - Oral, Solution, Solution - Intravenous, Liquid, Liquid - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous
Dilated Cardiomyopathies, Idiopathic
, 120.0 mg, 180.0 mg, 240.0 mg, 300.0 mg, 360.0 mg, 420.0 mg, 100.0 mg, 60.0 mg, 90.0 mg, 30.0 mg, 5.0 mg/mL, 1.0 mg/mL, 0.83 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Powder, for solution - Intravenous, Intravenous, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Injection, Injection - Intravenous, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Tablet, coated, Tablet, coated - Oral, Solution, Solution - Intravenous, Liquid, Liquid - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous
Proteinuria
, 120.0 mg, 180.0 mg, 240.0 mg, 300.0 mg, 360.0 mg, 420.0 mg, 100.0 mg, 60.0 mg, 90.0 mg, 30.0 mg, 5.0 mg/mL, 1.0 mg/mL, 0.83 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Powder, for solution - Intravenous, Intravenous, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Injection, Injection - Intravenous, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Tablet, coated, Tablet, coated - Oral, Solution, Solution - Intravenous, Liquid, Liquid - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous
Diabetic Neuropathy
, 120.0 mg, 180.0 mg, 240.0 mg, 300.0 mg, 360.0 mg, 420.0 mg, 100.0 mg, 60.0 mg, 90.0 mg, 30.0 mg, 5.0 mg/mL, 1.0 mg/mL, 0.83 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Powder, for solution - Intravenous, Intravenous, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Injection, Injection - Intravenous, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Tablet, coated, Tablet, coated - Oral, Solution, Solution - Intravenous, Liquid, Liquid - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous
Anginal Pain
, 120.0 mg, 180.0 mg, 240.0 mg, 300.0 mg, 360.0 mg, 420.0 mg, 100.0 mg, 60.0 mg, 90.0 mg, 30.0 mg, 5.0 mg/mL, 1.0 mg/mL, 0.83 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Powder, for solution - Intravenous, Intravenous, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Injection, Injection - Intravenous, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Tablet, coated, Tablet, coated - Oral, Solution, Solution - Intravenous, Liquid, Liquid - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous
Fissure;Anal
, 120.0 mg, 180.0 mg, 240.0 mg, 300.0 mg, 360.0 mg, 420.0 mg, 100.0 mg, 60.0 mg, 90.0 mg, 30.0 mg, 5.0 mg/mL, 1.0 mg/mL, 0.83 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Powder, for solution - Intravenous, Intravenous, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Injection, Injection - Intravenous, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Tablet, coated, Tablet, coated - Oral, Solution, Solution - Intravenous, Liquid, Liquid - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous
Chronic Stable Angina Pectoris
, 120.0 mg, 180.0 mg, 240.0 mg, 300.0 mg, 360.0 mg, 420.0 mg, 100.0 mg, 60.0 mg, 90.0 mg, 30.0 mg, 5.0 mg/mL, 1.0 mg/mL, 0.83 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Powder, for solution - Intravenous, Intravenous, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Injection, Injection - Intravenous, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Tablet, coated, Tablet, coated - Oral, Solution, Solution - Intravenous, Liquid, Liquid - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous
prophylaxis of migraine headaches
, 120.0 mg, 180.0 mg, 240.0 mg, 300.0 mg, 360.0 mg, 420.0 mg, 100.0 mg, 60.0 mg, 90.0 mg, 30.0 mg, 5.0 mg/mL, 1.0 mg/mL, 0.83 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Powder, for solution - Intravenous, Intravenous, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Injection, Injection - Intravenous, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Tablet, coated, Tablet, coated - Oral, Solution, Solution - Intravenous, Liquid, Liquid - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous
leg cramps
, 120.0 mg, 180.0 mg, 240.0 mg, 300.0 mg, 360.0 mg, 420.0 mg, 100.0 mg, 60.0 mg, 90.0 mg, 30.0 mg, 5.0 mg/mL, 1.0 mg/mL, 0.83 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Powder, for solution - Intravenous, Intravenous, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Injection, Injection - Intravenous, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Tablet, coated, Tablet, coated - Oral, Solution, Solution - Intravenous, Liquid, Liquid - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous

Warnings

Taztia Xt has ten contraindications and should not be utilized simultaneously with any of the conditions listed in the following table.Taztia Xt Contraindications
Condition
Risk Level
Notes
Heart Attack
Do Not Combine
accessory bypass tract
Do Not Combine
accessory bypass tract
Do Not Combine
absence of a functioning ventricular pacemaker
Do Not Combine
Ventricular Tachycardia
Do Not Combine
absence of a functioning ventricular pacemaker
Do Not Combine
third degree AV block
Do Not Combine
Pulmonary Congestion
Do Not Combine
Shock, Cardiogenic
Do Not Combine
Hypotension
Do Not Combine
There are 20 known major drug interactions with Taztia Xt.
Common Taztia Xt Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be decreased when combined with Diltiazem.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be decreased when combined with Diltiazem.
Alectinib
Major
The metabolism of Alectinib can be decreased when combined with Diltiazem.
Alfentanil
Major
The metabolism of Alfentanil can be decreased when combined with Diltiazem.
Amifostine
Major
Diltiazem may increase the hypotensive activities of Amifostine.
Taztia Xt Toxicity & Overdose RiskThe toxic dose of diltiazem in mice is between 415-740mg/kg and 560-810mg/kg in rats. Dogs have been found to have a safe dose of over 50mg/kg and 360mg/kg in monkeys has been found to be fatal. Overdoses of diltiazem, which range from less than 1g to 18g, can cause slow heart rate, low blood pressure, heart block, and cardiac failure. Treatment for overdose includes supportive measures and decontamination of the gastrointestinal system. Atropine, isoproterenol, fluids, vasopressors, and in
image of a doctor in a lab doing drug, clinical research

Taztia Xt Novel Uses: Which Conditions Have a Clinical Trial Featuring Taztia Xt?

At present, 228 active clinical trials are being conducted to assess the utility of Taztia XT for treating Atrial Fibrillation, Coronary Artery Spasm and Paroxysmal Supraventricular Tachycardia (PSVT).
Condition
Clinical Trials
Trial Phases
Pulmonary Hypertension
25 Actively Recruiting
Phase 2, Phase 3, Phase 1, Phase 4, Not Applicable, Early Phase 1
Atrial Fibrillation
145 Actively Recruiting
Not Applicable, Phase 2, Phase 4, Phase 1, Phase 3, Early Phase 1
Paroxysmal Supraventricular Tachycardia (PSVT)
2 Actively Recruiting
Phase 3, Phase 2
Anginal Pain
2 Actively Recruiting
Not Applicable, Phase 4
Chronic Stable Angina Pectoris
1 Actively Recruiting
Not Applicable
prophylaxis of migraine headaches
0 Actively Recruiting
Dilated Cardiomyopathies, Idiopathic
1 Actively Recruiting
Not Applicable
Coronary Artery Vasospasm
0 Actively Recruiting
Fissure;Anal
0 Actively Recruiting
Angina Pectoris, Variant
0 Actively Recruiting
Hypertensive disease
19 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Diabetic Neuropathy
22 Actively Recruiting
Phase 2, Not Applicable, Phase 1
Proteinuria
5 Actively Recruiting
Phase 2, Phase 3, Phase 4
leg cramps
0 Actively Recruiting

Taztia Xt Reviews: What are patients saying about Taztia Xt?

5Patient Review
4/5/2012
Taztia Xt for Ventricular Rate Control in Atrial Fibrillation
I stopped taking Taztia XT because it was causing me to experience dizziness and severe hallucinations.
5Patient Review
11/18/2008
Taztia Xt for High Blood Pressure
5Patient Review
6/18/2010
Taztia Xt for High Blood Pressure
I haven't had any issues while taking this medication, and I'm really pleased with it!
5Patient Review
9/24/2011
Taztia Xt for High Blood Pressure
The treatment made me dizzy and affected my vision.
4.7Patient Review
10/1/2013
Taztia Xt for High Blood Pressure
I've been taking this medication for years at the insistence of my doctor, and while it does help lower my blood pressure, the side effects are not worth it. Dizziness, blurred vision, fatigue, and general malaise are all common complaints I have. Additionally, heat really bothers me when I'm on this medication.
4.7Patient Review
12/6/2014
Taztia Xt for High Blood Pressure
I'm mostly pleased with this medication. I have dealt with occasional dizzy spells, but it's a small price to pay for having lower blood pressure and pulse rate.
4.7Patient Review
9/19/2008
Taztia Xt for High Blood Pressure
4Patient Review
1/27/2010
Taztia Xt for High Blood Pressure
3.7Patient Review
1/10/2013
Taztia Xt for High Blood Pressure
This has been successful in keeping my blood pressure within a normal range. I feel much better as a result.
3Patient Review
5/22/2015
Taztia Xt for High Blood Pressure
While this medication has been effective in lowering my blood pressure, I have experienced debilitating leg pain as a side effect. This pain has made it difficult to walk or stand for long periods of time, and is likely due to calcium deficiency caused by the drug.
3Patient Review
8/21/2013
Taztia Xt for High Blood Pressure
It's frustrating that this treatment takes a while to work and only lasts for 6-8 hours.
3Patient Review
4/8/2013
Taztia Xt for Ventricular Rate Control in Atrial Fibrillation
I initially gained a lot of weight suddenly, and my blood pressure became uncontrolled as a result. I started taking this medication alongside Quinapril, which helped to get my BP under control. However, I've since lost 85lbs and my BP is now below normal (110/70) even without the medication. It's probably time to reduce my dosage of Quinapril as well.
3Patient Review
11/15/2011
Taztia Xt for High Blood Pressure
I'm not sure this treatment has done much for me. I was shocked into sinus rhythm in Sept, but since then my heart rate has been increased and I've gained a pound per week. On top of that, now I'm itching all the time.
2.3Patient Review
8/14/2013
Taztia Xt for High Blood Pressure
I've been on this medication for around twelve months now, and I haven't seen much success. However, it does help to lower my heart rate.
2.3Patient Review
12/23/2008
Taztia Xt for Ventricular Rate Control in Atrial Fibrillation
2Patient Review
10/21/2008
Taztia Xt for High Blood Pressure
1.3Patient Review
9/9/2016
Taztia Xt for High Blood Pressure
Blurry vision and severe pain in lower extremities were just a couple of the issues I experienced while taking this medication. Additionally, it didn't really do much to help my blood pressure. Needless to say, I stopped taking it as soon as possible.
1Patient Review
2/5/2010
Taztia Xt for High Blood Pressure
This medicine effectively controls my irregular heartbeat.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about taztia xt

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Cartia XT the same as Cardizem CD?

"Diltiazem (Cartia XT, Cardizem CD) is an oral medication used to treat high blood pressure and angina. It is taken once or twice daily."

Answered by AI

What is Taztia XT used for?

"Diltiazem is used to lower high blood pressure and prevent chest pain. Reducing high blood pressure helps to avoid strokes, heart attacks, and kidney problems. With regular use, diltiazem can decrease the number and severity of episodes of chest pain caused by angina."

Answered by AI

What is the drug diltiazem used to treat?

"If you have high blood pressure, diltiazem can help prevent heart disease, heart attacks, strokes, and chest pain caused by angina. It can also help heal an anal fissure."

Answered by AI

Is Taztia the same as diltiazem?

"Taztia Xt is also occasionally used to treat arrhythmias (irregular heartbeats).

The prescription medication Taztia Xt is used to treat hypertension (high blood pressure) and chest pain caused by angina. Taztia Xt is the brand-name drug and diltiazem is its generic version. Taztia Xt is also occasionally used to treat arrhythmias (irregular heartbeats)."

Answered by AI

Clinical Trials for Taztia Xt

Have you considered Taztia Xt clinical trials? We made a collection of clinical trials featuring Taztia Xt, we think they might fit your search criteria.
Have you considered Taztia Xt clinical trials? We made a collection of clinical trials featuring Taztia Xt, we think they might fit your search criteria.
Have you considered Taztia Xt clinical trials? We made a collection of clinical trials featuring Taztia Xt, we think they might fit your search criteria.
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