Taxol

Increased Intra Ocular Pressure (IOP), Hypertensive disease, Ocular Hypertension + 2 more
Treatment
1 FDA approval
20 Active Studies for Taxol

What is Taxol

BetaxololThe Generic name of this drug
Treatment SummaryA cardioselective beta-1-adrenergic antagonist is a type of medication used to block the effects of the hormone adrenaline. It does not have any effects of its own and does not trigger any activity in the body.
Kerloneis the brand name
image of different drug pills on a surface
Taxol Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Kerlone
Betaxolol
1989
19

Approved as Treatment by the FDA

Betaxolol, also known as Kerlone, is approved by the FDA for 1 uses such as Hypertensive disease .
Hypertensive disease
Helps manage High Blood Pressure (Hypertension)

Effectiveness

How Taxol Affects PatientsBetaxolol is a drug used to treat high blood pressure, irregular heartbeats, heart disease, and glaucoma. It works by blocking certain receptors in the heart that cause an increase in heart rate and blood pressure. This helps to reduce the amount of oxygen the heart needs and lowers the heart rate and blood pressure. Betaxolol is also known to stop the release of a hormone from the kidneys that causes blood vessels to narrow. It is a relatively safe drug with no known side effects.
How Taxol works in the bodyBetaxolol reduces heart rate, blood pressure, and the activity of certain muscles. It does this by blocking the body's natural response to catecholamine hormones that stimulate these functions. This can also lead to reduced reflex reactions and breathing difficulties.

When to interrupt dosage

The proposed measure of Taxol is contingent upon the diagnosed condition, including Glaucoma, Open-Angle, Increased Intra Ocular Pressure (IOP) and Betoptic. The amount of dosage fluctuates, depending on the technique of delivery (e.g. Kit or Tablet, coated) presented in the table beneath.
Condition
Dosage
Administration
Hypertensive disease
, 10.0 mg, 20.0 mg, 5.0 mg/mL, 5.6 mg/mL, 0.5 %, 0.25 %, 2.8 mg/mL, 2.5 mg/mL
, Oral, Tablet, coated, Tablet, coated - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Solution, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Suspension, Suspension - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Kit, Kit - Ophthalmic
Increased Intra Ocular Pressure (IOP)
, 10.0 mg, 20.0 mg, 5.0 mg/mL, 5.6 mg/mL, 0.5 %, 0.25 %, 2.8 mg/mL, 2.5 mg/mL
, Oral, Tablet, coated, Tablet, coated - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Solution, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Suspension, Suspension - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Kit, Kit - Ophthalmic
Ocular Hypertension
, 10.0 mg, 20.0 mg, 5.0 mg/mL, 5.6 mg/mL, 0.5 %, 0.25 %, 2.8 mg/mL, 2.5 mg/mL
, Oral, Tablet, coated, Tablet, coated - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Solution, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Suspension, Suspension - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Kit, Kit - Ophthalmic
Betoptic
, 10.0 mg, 20.0 mg, 5.0 mg/mL, 5.6 mg/mL, 0.5 %, 0.25 %, 2.8 mg/mL, 2.5 mg/mL
, Oral, Tablet, coated, Tablet, coated - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Solution, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Suspension, Suspension - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Kit, Kit - Ophthalmic
Glaucoma, Open-Angle
, 10.0 mg, 20.0 mg, 5.0 mg/mL, 5.6 mg/mL, 0.5 %, 0.25 %, 2.8 mg/mL, 2.5 mg/mL
, Oral, Tablet, coated, Tablet, coated - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Solution, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Suspension, Suspension - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Kit, Kit - Ophthalmic

Warnings

There are 20 known major drug interactions with Taxol.
Common Taxol Drug Interactions
Drug Name
Risk Level
Description
4-Bromo-2,5-dimethoxyphenethylamine
Major
The therapeutic efficacy of 4-Bromo-2,5-dimethoxyphenethylamine can be decreased when used in combination with Betaxolol.
4-Methoxyamphetamine
Major
The therapeutic efficacy of 4-Methoxyamphetamine can be decreased when used in combination with Betaxolol.
Abediterol
Major
The therapeutic efficacy of Abediterol can be decreased when used in combination with Betaxolol.
Adrafinil
Major
The therapeutic efficacy of Adrafinil can be decreased when used in combination with Betaxolol.
Agrostis gigantea pollen
Major
The risk of a hypersensitivity reaction to Agrostis gigantea pollen is increased when it is combined with Betaxolol.
Taxol Toxicity & Overdose RiskThe toxicity of betaxolol has been tested on mice and rats, with the toxic dose in mice being 350 to 400 mg/kg, and 860 to 980 mg/kg in rats. Signs of overdosing on this drug include slow heartbeat, heart failure, low blood pressure, difficulty breathing, and low blood sugar.
image of a doctor in a lab doing drug, clinical research

Taxol Novel Uses: Which Conditions Have a Clinical Trial Featuring Taxol?

49 active clinical trials are being conducted to assess the capability of Taxol in reducing Increased Intra Ocular Pressure (IOP), Betoptic and Hypertensive disease.
Condition
Clinical Trials
Trial Phases
Increased Intra Ocular Pressure (IOP)
0 Actively Recruiting
Betoptic
0 Actively Recruiting
Hypertensive disease
19 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Ocular Hypertension
22 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Phase 3, Phase 4
Glaucoma, Open-Angle
11 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Phase 4, Phase 3

Taxol Reviews: What are patients saying about Taxol?

5Patient Review
10/19/2013
Taxol for Locally Advanced Breast Carcinoma
I generally feel great after the first few days of treatment. After my second round, though, I started having really severe tingling and itching in my hands, feet, and vaginal area. Had to skip my fourth round so that my body could heal.
5Patient Review
5/1/2013
Taxol for HER2 Positive Breast Cancer
I experienced some dizziness, leg and feet aches, swelling of both feet, rapid heart rate, difficulty breathing, complete hair loss, exhaustion.
4.3Patient Review
6/15/2011
Taxol for Breast Cancer that has Spread to Another Part of the Body
3.7Patient Review
6/19/2012
Taxol for Breast Cancer that has Spread to Another Part of the Body
I felt pretty tired after taking this, and my stomach was upset which made it hard to eat. I'm not sure if that was from the drug or something else though.
3.3Patient Review
8/28/2013
Taxol for Locally Advanced Breast Carcinoma
I only started taking this yesterday, so it's still early to tell how well it works.
3Patient Review
1/10/2012
Taxol for Non-Small Cell Lung Cancer
The tumor is getting smaller. This is my fifth dose and I don't feel bad. I loss hair, but sometimes I just feel tired. So far no negative effects that I can tell, so fingers crossed this works for me.
3Patient Review
8/25/2011
Taxol for HER2 Positive Breast Cancer
2.7Patient Review
11/19/2011
Taxol for Non-Small Cell Lung Cancer
I was using Abraxane, but it made me very ill. My oncologist changed my treatment to Taxol, which has been much easier for me to tolerate. I only experience flushing of the face on the second day of treatment. Otherwise, it's not been too bad.
1.7Patient Review
3/16/2014
Taxol for Cancer Involving the Head or Neck
Taxol is tough--it takes away your appetite and makes you incredibly tired. Additionally, it changes the color of your skin.
1Patient Review
11/17/2018
Taxol for Stomach Cancer
My husband died very soon after receiving this treatment. He started having problems about ten days in, and then had to be hospitalized because he couldn't breathe. This stuff should not be legal.
1Patient Review
2/19/2016
Taxol for Cancer in the Lining of the Uterus
My mother had a serious allergic reaction 10 minutes into the first treatment. Her heart stopped and she was revived thankfully. However, she spent 4 days in the hospital. She is very active and seems to be in normal health, but she vowed to never try chemo again because of this!
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about taxol

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Taxol for breast cancer?

"Taxol, or paclitaxel, is a drug used to treat certain women with advanced breast or ovarian cancer. Paclitaxel is derived from the bark of the Pacific yew tree."

Answered by AI

What are side effects of Taxol?

"The following effects may occur: nausea, vomiting, diarrhea, mouth sores, muscle/joint pain, numbness/tingling/burning of the hands/feet, flushing, dizziness, or drowsiness. If you experience any of these effects, tell your doctor. You may also experience temporary hair loss, but normal hair growth should resume after treatment is finished."

Answered by AI

Is Taxol still used?

"Taxol is a drug that kills cancer cells and is used to treat various types of cancer, including breast cancer, ovarian cancer, non-small cell lung cancer, pancreatic cancer, and AIDS-related Kaposi sarcoma. It is included on the World Health Organization's Model List of Essential Medicines."

Answered by AI

How long does Taxol chemo take?

"Each treatment takes a different amount of time. Some treatments take 1 hour, some treatments take 3 hours, and some treatments take 24 hours."

Answered by AI

Clinical Trials for Taxol

Have you considered Taxol clinical trials? We made a collection of clinical trials featuring Taxol, we think they might fit your search criteria.
Have you considered Taxol clinical trials? We made a collection of clinical trials featuring Taxol, we think they might fit your search criteria.
Have you considered Taxol clinical trials? We made a collection of clinical trials featuring Taxol, we think they might fit your search criteria.