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What is Starlix
NateglinideThe Generic name of this drug
Treatment SummaryNateglinide is an oral medication used to treat non-insulin-dependent diabetes mellitus (NIDDM). It is part of the meglitinide class of drugs and works by stimulating the pancreas to release insulin. Nateglinide should be taken with meals, and skipped if a meal is missed. It takes about one month for the drug to begin lowering fasting blood glucose levels. Nateglinide may cause a slight increase in weight, but this is usually lower than other diabetes medications. It can also cause hypoglycemia, but this is less common than with sulfonylureas.
Starlixis the brand name
Starlix Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Starlix
Nateglinide
2000
40
Approved as Treatment by the FDA
Nateglinide, also called Starlix, is approved by the FDA for 1 uses including Type 2 Diabetes .Type 2 Diabetes
Helps manage Type 2 Diabetes Mellitus
Effectiveness
How Starlix Affects PatientsNateglinide helps the body to produce insulin by controlling how much electricity flows through the cell membranes in the pancreas. When there is not enough glucose (sugar) in the body, electricity is allowed to flow through these cell membranes, which causes the release of insulin. Nateglinide helps to close off these cell membranes when glucose levels are high, which increases the release of insulin.
How Starlix works in the bodyNateglinide works by helping the body release more insulin in response to glucose. It's most effective after meals, when glucose levels are high, and takes a few weeks to start lowering fasting blood sugar levels. Unlike other diabetes drugs, nateglinide only affects the pancreas and doesn't affect other parts of the body. It also only kicks in at certain glucose levels, so it won't cause too much insulin to be released when it's not necessary.
When to interrupt dosage
The allotment of Starlix is determined by the identified ailment. The measure of dosage fluctuates, in accordance with the technique of delivery (e.g. Tablet, film coated - Oral or Tablet) laid out in the table beneath.Condition
Dosage
Administration
Type 2 Diabetes
, 60.0 mg, 120.0 mg, 180.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, film coated, Tablet, film coated - Oral
Warnings
Starlix has two contraindications, so it should be avoided when you are experiencing any of the conditions in the following table.Starlix ContraindicationsCondition
Risk Level
Notes
Diabetic Ketoacidosis
Do Not Combine
Type 1 Diabetes
Do Not Combine
Common Starlix Drug Interactions
Drug Name
Risk Level
Description
Amitriptyline
Major
The metabolism of Amitriptyline can be decreased when combined with Nateglinide.
Amoxapine
Major
The metabolism of Amoxapine can be decreased when combined with Nateglinide.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Nateglinide.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Nateglinide.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Nateglinide.
Starlix Toxicity & Overdose RiskTaking too much of this drug can lead to abnormally low blood sugar levels and related symptoms like confusion, dizziness, and sweating.
Starlix Novel Uses: Which Conditions Have a Clinical Trial Featuring Starlix?
162 active studies are investigating the potential of Starlix in managing Type 2 Diabetes.Condition
Clinical Trials
Trial Phases
Type 2 Diabetes
192 Actively Recruiting
Phase 2, Not Applicable, Early Phase 1, Phase 1, Phase 4, Phase 3
Starlix Reviews: What are patients saying about Starlix?
5Patient Review
8/16/2010 I've been using this medication for over five years, and it has really helped to regulate my blood sugar levels. I still have some high readings in the morning, but they usually return to normal by lunchtime.
5Patient Review
2/4/2012 I've been on this medication for two months. When I started, my blood sugar remained low; however, now it's gradually increased to the mid-to-high 100s range. My diet hasn't changed at all, so I'm not sure why there's been this change.
5Patient Review
12/30/20085Patient Review
2/21/20094.7Patient Review
2/26/2009 Starlix has been great for keeping my blood sugar levels in check.
4.7Patient Review
6/11/2010 I've been taking this medication for five days as directed, but my blood sugar is still high. Not sure if it's effective yet or not.
4.3Patient Review
7/31/2010 I had excellent results with this treatment for seven years, but now I have to take another drug in addition to it. The generic Starlex (nateglinde) tastes terrible.
4.3Patient Review
6/23/2010 I don't really work out that often.
4.3Patient Review
2/5/20094Patient Review
5/2/2010 I've been taking this medication for over a month now and have experienced intense lower back pain as a result.
4Patient Review
4/12/2012 I've been experiencing some pretty intense headaches, nausea, and tingling in my toes. My mouth feels really dry too.
3.7Patient Review
6/27/2013 I've been taking this medication for about ten days now, three times per day. I'm also taking Metformin twice a day. While my levels have improved somewhat, I've unfortunately gained five pounds. Another downside is that I've been constipated since starting the medication.
3.3Patient Review
10/4/2013 My A1C has been around 7.5 for the two years I've been taking Starlix. I don't see a real difference in my numbers, but I feel that anything to get them down is worth it. So, if you're considering this medication, I say go for it.
2.7Patient Review
3/13/2012 This drug helped me stay at my ideal weight without spiking my blood sugar levels. I didn't experience any negative side effects, which was great.
2.3Patient Review
7/31/2011 I've been taking this medication since 2002. If I don't take it before breakfast and dinner, my sugar levels can get dangerously high--up to 200 or just past. I feel like I have to eat a certain amount at each meal to keep from getting low blood sugar, though, which may be preventing me from losing weight.
2.3Patient Review
8/9/2017 So far, Starlix doesn't seem to be working as intended. My blood sugar has been going up rather than down since starting this medication just three days ago.
2Patient Review
6/22/2009 My blood sugar increased from 125 to 180.
1.7Patient Review
11/15/2011 I took this drug for three weeks and saw significant weight gain, vision problems, and cardiovascular issues. I'm feeling more energetic now that I've stopped taking it, but the weight gain and vision problems persist. I'm currently working with my family doctor and optometrist to try and resolve these issues.
1.7Patient Review
1/15/2009Patient Q&A Section about starlix
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What kind of drug is Starlix?
"Starlix is a medication that can be taken in addition to diet and exercise to help control blood sugar levels in people with type 2 diabetes."
Answered by AI
Is Starlix an insulin?
"Starlix is an oral diabetes medicine that helps to regulate blood sugar levels. This medicine encourages the body to respond more effectively to insulin produced by the pancreas. Starlix is most effective when used in combination with diet and exercise to improve blood sugar control in adults suffering from type 2 diabetes mellitus."
Answered by AI
Is Starlix discontinued?
"The existing supply of Starlix will be gone by January 2014 because of the current demand. This decision was made because of the available alternative treatments and the diminishing market demand for Starlix. This is not because of any safety issue."
Answered by AI
What is Starlix used for?
"It is used in people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. It [insulin] works by stimulating the body to produce more [insulin]."
Answered by AI