Starlix

Type 2 Diabetes
Treatment
2 FDA approvals
20 Active Studies for Starlix

What is Starlix

NateglinideThe Generic name of this drug
Treatment SummaryNateglinide is an oral medication used to treat non-insulin-dependent diabetes mellitus (NIDDM). It is part of the meglitinide class of drugs and works by stimulating the pancreas to release insulin. Nateglinide should be taken with meals, and skipped if a meal is missed. It takes about one month for the drug to begin lowering fasting blood glucose levels. Nateglinide may cause a slight increase in weight, but this is usually lower than other diabetes medications. It can also cause hypoglycemia, but this is less common than with sulfonylureas.
Starlixis the brand name
Starlix Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Starlix
Nateglinide
2000
40

Approved as Treatment by the FDA

Nateglinide, also called Starlix, is approved by the FDA for 2 uses including Type 2 Diabetes Mellitus and Type 2 Diabetes .
Type 2 Diabetes Mellitus
Helps manage Type 2 Diabetes Mellitus
Type 2 Diabetes
Helps manage Type 2 Diabetes Mellitus

Effectiveness

How Starlix Affects PatientsNateglinide helps the body to produce insulin by controlling how much electricity flows through the cell membranes in the pancreas. When there is not enough glucose (sugar) in the body, electricity is allowed to flow through these cell membranes, which causes the release of insulin. Nateglinide helps to close off these cell membranes when glucose levels are high, which increases the release of insulin.
How Starlix works in the bodyNateglinide works by helping the body release more insulin in response to glucose. It's most effective after meals, when glucose levels are high, and takes a few weeks to start lowering fasting blood sugar levels. Unlike other diabetes drugs, nateglinide only affects the pancreas and doesn't affect other parts of the body. It also only kicks in at certain glucose levels, so it won't cause too much insulin to be released when it's not necessary.

When to interrupt dosage

The allotment of Starlix is determined by the identified ailment. The measure of dosage fluctuates, in accordance with the technique of delivery (e.g. Tablet, film coated - Oral or Tablet) laid out in the table beneath.
Condition
Dosage
Administration
Type 2 Diabetes
, 60.0 mg, 120.0 mg, 180.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, film coated, Tablet, film coated - Oral

Warnings

Starlix has two contraindications, so it should be avoided when you are experiencing any of the conditions in the following table.Starlix Contraindications
Condition
Risk Level
Notes
Diabetic Ketoacidosis
Do Not Combine
Type 1 Diabetes
Do Not Combine
There are 20 known major drug interactions with Starlix.
Common Starlix Drug Interactions
Drug Name
Risk Level
Description
Amitriptyline
Major
The metabolism of Amitriptyline can be decreased when combined with Nateglinide.
Amoxapine
Major
The metabolism of Amoxapine can be decreased when combined with Nateglinide.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Nateglinide.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Nateglinide.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Nateglinide.
Starlix Toxicity & Overdose RiskTaking too much of this drug can lead to abnormally low blood sugar levels and related symptoms like confusion, dizziness, and sweating.
image of a doctor in a lab doing drug, clinical research

Starlix Novel Uses: Which Conditions Have a Clinical Trial Featuring Starlix?

162 active studies are investigating the potential of Starlix in managing Type 2 Diabetes.
Condition
Clinical Trials
Trial Phases
Type 2 Diabetes
174 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3, Phase 4, Early Phase 1

Starlix Reviews: What are patients saying about Starlix?

5Patient Review
8/16/2010
Starlix for Type 2 Diabetes Mellitus
I've been using this medication for over five years, and it has really helped to regulate my blood sugar levels. I still have some high readings in the morning, but they usually return to normal by lunchtime.
5Patient Review
2/4/2012
Starlix for Type 2 Diabetes Mellitus
I've been on this medication for two months. When I started, my blood sugar remained low; however, now it's gradually increased to the mid-to-high 100s range. My diet hasn't changed at all, so I'm not sure why there's been this change.
5Patient Review
12/30/2008
Starlix for Type 2 Diabetes Mellitus
5Patient Review
2/21/2009
Starlix for Type 2 Diabetes Mellitus
4.7Patient Review
2/26/2009
Starlix for Type 2 Diabetes Mellitus
Starlix has been great for keeping my blood sugar levels in check.
View All Reviews
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Patient Q&A Section about starlix

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What kind of drug is Starlix?

"Starlix is a medication that can be taken in addition to diet and exercise to help control blood sugar levels in people with type 2 diabetes."

Answered by AI

Is Starlix an insulin?

"Starlix is an oral diabetes medicine that helps to regulate blood sugar levels. This medicine encourages the body to respond more effectively to insulin produced by the pancreas. Starlix is most effective when used in combination with diet and exercise to improve blood sugar control in adults suffering from type 2 diabetes mellitus."

Answered by AI

Is Starlix discontinued?

"The existing supply of Starlix will be gone by January 2014 because of the current demand. This decision was made because of the available alternative treatments and the diminishing market demand for Starlix. This is not because of any safety issue."

Answered by AI

What is Starlix used for?

"It is used in people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. It [insulin] works by stimulating the body to produce more [insulin]."

Answered by AI

Clinical Trials for Starlix

Have you considered Starlix clinical trials? We made a collection of clinical trials featuring Starlix, we think they might fit your search criteria.
Have you considered Starlix clinical trials? We made a collection of clinical trials featuring Starlix, we think they might fit your search criteria.
Have you considered Starlix clinical trials? We made a collection of clinical trials featuring Starlix, we think they might fit your search criteria.
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