Rocephin

Lyme Polyradiculitis, Chancroid, Whipple Disease + 33 more

Treatment

24 FDA approvals

20 Active Studies for Rocephin

What is Rocephin

Ceftriaxone

The Generic name of this drug

Treatment Summary

Ceftriaxone is an antibiotic used to treat a wide range of bacterial infections. It is a third-generation cephalosporin, meaning it is stronger than first or second-generation cephalosporins and can penetrate the brain, eyes, and inner ear better. It has a long half-life and can be administered once or twice daily, making it a convenient option. Ceftriaxone is effective against many drug-resistant bacteria, but not methicillin-susceptible S. aureus. It is generally well-tolerated with few side effects.

Rocephin

is the brand name

image of different drug pills on a surface

Rocephin Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Rocephin

Ceftriaxone

1993

165

Approved as Treatment by the FDA

Ceftriaxone, commonly known as Rocephin, is approved by the FDA for 24 uses including Gonorrhea and Bacterial Infections .

Gonorrhea

Bacterial Infections

Lower respiratory tract infection bacterial

bacterial otitis media

uncomplicated Gonorrhea

complicated Bacterial Urinary Tract Infections

Skin and Subcutaneous Tissue Bacterial Infections

Sepsis Bacterial

Abdominal Infection

Bone and Joint Infections

prophylaxis of Postoperative Infections

uncomplicated Urinary tract infection bacterial

Urinary Tract Infection (UTI)

Meningitis, Bacterial

Bacterial Infections

Sepsis

Osteomyelitis

Intraabdominal Infections

Urinary Tract Infections

Urinary Tract Infections

Postoperative Infections

Bacteria

Otitis Media

Pelvic Inflammatory Disease

Effectiveness

How Rocephin Affects Patients

Ceftriaxone is an antibiotic used to treat bacterial infections caused by certain bacteria. It works by stopping the growth of bacteria and preventing them from making their cell walls, which keeps the bacteria from multiplying. Ceftriaxone is resistant to many different kinds of antibiotics, but resistance can still form if the bacteria make changes to their cell wall or make it harder for the antibiotic to enter. It should not be mixed with calcium-containing substances, and its use may cause bile and gallbladder problems.

How Rocephin works in the body

Ceftriaxone stops bacteria from forming their cell walls. It does this by attaching to the enzymes in the bacterial cell wall, which are responsible for forming the wall. When the drug binds to these enzymes, they can no longer do their job, and the cell wall cannot be built. Without a cell wall, the bacteria can't survive.

When to interrupt dosage

The endorsed dosage of Rocephin is contingent upon the indicated condition, including Otitis Media, Conjunctivitis and Sepsis Bacterial. The amount of dosage also depends on the approach of delivery (e.g. Powder, for solution or Solution) outlined in the table beneath.

Condition

Dosage

Administration

Sepsis

100.0 mg/mL, , 2000.0 mg, 500.0 mg, 250.0 mg, 200.0 mg/mL, 1000.0 mg, 10000.0 mg, 100000.0 mg

, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Intramuscular, Injection, powder, for solution - Intramuscular, Powder, for solution, Powder, for solution - Intramuscular; Intravenous, Powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution, Solution - Intravenous, Kit - Intramuscular; Intravenous, Kit, Kit - Intramuscular; Intravenous; Topical, Intramuscular; Intravenous; Topical

Sinusitis

100.0 mg/mL, , 2000.0 mg, 500.0 mg, 250.0 mg, 200.0 mg/mL, 1000.0 mg, 10000.0 mg, 100000.0 mg

, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Intramuscular, Injection, powder, for solution - Intramuscular, Powder, for solution, Powder, for solution - Intramuscular; Intravenous, Powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution, Solution - Intravenous, Kit - Intramuscular; Intravenous, Kit, Kit - Intramuscular; Intravenous; Topical, Intramuscular; Intravenous; Topical

Gonococcal arthritis

100.0 mg/mL, , 2000.0 mg, 500.0 mg, 250.0 mg, 200.0 mg/mL, 1000.0 mg, 10000.0 mg, 100000.0 mg

, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Intramuscular, Injection, powder, for solution - Intramuscular, Powder, for solution, Powder, for solution - Intramuscular; Intravenous, Powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution, Solution - Intravenous, Kit - Intramuscular; Intravenous, Kit, Kit - Intramuscular; Intravenous; Topical, Intramuscular; Intravenous; Topical

Shigellosis

100.0 mg/mL, , 2000.0 mg, 500.0 mg, 250.0 mg, 200.0 mg/mL, 1000.0 mg, 10000.0 mg, 100000.0 mg

, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Intramuscular, Injection, powder, for solution - Intramuscular, Powder, for solution, Powder, for solution - Intramuscular; Intravenous, Powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution, Solution - Intravenous, Kit - Intramuscular; Intravenous, Kit, Kit - Intramuscular; Intravenous; Topical, Intramuscular; Intravenous; Topical

Gonorrhea

100.0 mg/mL, , 2000.0 mg, 500.0 mg, 250.0 mg, 200.0 mg/mL, 1000.0 mg, 10000.0 mg, 100000.0 mg

, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Intramuscular, Injection, powder, for solution - Intramuscular, Powder, for solution, Powder, for solution - Intramuscular; Intravenous, Powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution, Solution - Intravenous, Kit - Intramuscular; Intravenous, Kit, Kit - Intramuscular; Intravenous; Topical, Intramuscular; Intravenous; Topical

Pelvic Inflammatory Disease

100.0 mg/mL, , 2000.0 mg, 500.0 mg, 250.0 mg, 200.0 mg/mL, 1000.0 mg, 10000.0 mg, 100000.0 mg

, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Intramuscular, Injection, powder, for solution - Intramuscular, Powder, for solution, Powder, for solution - Intramuscular; Intravenous, Powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution, Solution - Intravenous, Kit - Intramuscular; Intravenous, Kit, Kit - Intramuscular; Intravenous; Topical, Intramuscular; Intravenous; Topical

Arthritis, Infectious

100.0 mg/mL, , 2000.0 mg, 500.0 mg, 250.0 mg, 200.0 mg/mL, 1000.0 mg, 10000.0 mg, 100000.0 mg

, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Intramuscular, Injection, powder, for solution - Intramuscular, Powder, for solution, Powder, for solution - Intramuscular; Intravenous, Powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution, Solution - Intravenous, Kit - Intramuscular; Intravenous, Kit, Kit - Intramuscular; Intravenous; Topical, Intramuscular; Intravenous; Topical

Community Acquired Pneumonia (CAP)

100.0 mg/mL, , 2000.0 mg, 500.0 mg, 250.0 mg, 200.0 mg/mL, 1000.0 mg, 10000.0 mg, 100000.0 mg

, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Intramuscular, Injection, powder, for solution - Intramuscular, Powder, for solution, Powder, for solution - Intramuscular; Intravenous, Powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution, Solution - Intravenous, Kit - Intramuscular; Intravenous, Kit, Kit - Intramuscular; Intravenous; Topical, Intramuscular; Intravenous; Topical

Lyme Polyradiculitis

100.0 mg/mL, , 2000.0 mg, 500.0 mg, 250.0 mg, 200.0 mg/mL, 1000.0 mg, 10000.0 mg, 100000.0 mg

, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Intramuscular, Injection, powder, for solution - Intramuscular, Powder, for solution, Powder, for solution - Intramuscular; Intravenous, Powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution, Solution - Intravenous, Kit - Intramuscular; Intravenous, Kit, Kit - Intramuscular; Intravenous; Topical, Intramuscular; Intravenous; Topical

Epiglottitis

100.0 mg/mL, , 2000.0 mg, 500.0 mg, 250.0 mg, 200.0 mg/mL, 1000.0 mg, 10000.0 mg, 100000.0 mg

, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Intramuscular, Injection, powder, for solution - Intramuscular, Powder, for solution, Powder, for solution - Intramuscular; Intravenous, Powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution, Solution - Intravenous, Kit - Intramuscular; Intravenous, Kit, Kit - Intramuscular; Intravenous; Topical, Intramuscular; Intravenous; Topical

Epididymitis

100.0 mg/mL, , 2000.0 mg, 500.0 mg, 250.0 mg, 200.0 mg/mL, 1000.0 mg, 10000.0 mg, 100000.0 mg

, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Intramuscular, Injection, powder, for solution - Intramuscular, Powder, for solution, Powder, for solution - Intramuscular; Intravenous, Powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution, Solution - Intravenous, Kit - Intramuscular; Intravenous, Kit, Kit - Intramuscular; Intravenous; Topical, Intramuscular; Intravenous; Topical

Bacteria

100.0 mg/mL, , 2000.0 mg, 500.0 mg, 250.0 mg, 200.0 mg/mL, 1000.0 mg, 10000.0 mg, 100000.0 mg

, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Intramuscular, Injection, powder, for solution - Intramuscular, Powder, for solution, Powder, for solution - Intramuscular; Intravenous, Powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution, Solution - Intravenous, Kit - Intramuscular; Intravenous, Kit, Kit - Intramuscular; Intravenous; Topical, Intramuscular; Intravenous; Topical

Vulvovaginitis

100.0 mg/mL, , 2000.0 mg, 500.0 mg, 250.0 mg, 200.0 mg/mL, 1000.0 mg, 10000.0 mg, 100000.0 mg

, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Intramuscular, Injection, powder, for solution - Intramuscular, Powder, for solution, Powder, for solution - Intramuscular; Intravenous, Powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution, Solution - Intravenous, Kit - Intramuscular; Intravenous, Kit, Kit - Intramuscular; Intravenous; Topical, Intramuscular; Intravenous; Topical

Urinary Tract Infections

100.0 mg/mL, , 2000.0 mg, 500.0 mg, 250.0 mg, 200.0 mg/mL, 1000.0 mg, 10000.0 mg, 100000.0 mg

, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Intramuscular, Injection, powder, for solution - Intramuscular, Powder, for solution, Powder, for solution - Intramuscular; Intravenous, Powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution, Solution - Intravenous, Kit - Intramuscular; Intravenous, Kit, Kit - Intramuscular; Intravenous; Topical, Intramuscular; Intravenous; Topical

Syphilis

100.0 mg/mL, , 2000.0 mg, 500.0 mg, 250.0 mg, 200.0 mg/mL, 1000.0 mg, 10000.0 mg, 100000.0 mg

, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Intramuscular, Injection, powder, for solution - Intramuscular, Powder, for solution, Powder, for solution - Intramuscular; Intravenous, Powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution, Solution - Intravenous, Kit - Intramuscular; Intravenous, Kit, Kit - Intramuscular; Intravenous; Topical, Intramuscular; Intravenous; Topical

Urinary Tract Infections

100.0 mg/mL, , 2000.0 mg, 500.0 mg, 250.0 mg, 200.0 mg/mL, 1000.0 mg, 10000.0 mg, 100000.0 mg

, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Intramuscular, Injection, powder, for solution - Intramuscular, Powder, for solution, Powder, for solution - Intramuscular; Intravenous, Powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution, Solution - Intravenous, Kit - Intramuscular; Intravenous, Kit, Kit - Intramuscular; Intravenous; Topical, Intramuscular; Intravenous; Topical

Intraabdominal Infections

100.0 mg/mL, , 2000.0 mg, 500.0 mg, 250.0 mg, 200.0 mg/mL, 1000.0 mg, 10000.0 mg, 100000.0 mg

, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Intramuscular, Injection, powder, for solution - Intramuscular, Powder, for solution, Powder, for solution - Intramuscular; Intravenous, Powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution, Solution - Intravenous, Kit - Intramuscular; Intravenous, Kit, Kit - Intramuscular; Intravenous; Topical, Intramuscular; Intravenous; Topical

Conjunctivitis

100.0 mg/mL, , 2000.0 mg, 500.0 mg, 250.0 mg, 200.0 mg/mL, 1000.0 mg, 10000.0 mg, 100000.0 mg

, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Intramuscular, Injection, powder, for solution - Intramuscular, Powder, for solution, Powder, for solution - Intramuscular; Intravenous, Powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution, Solution - Intravenous, Kit - Intramuscular; Intravenous, Kit, Kit - Intramuscular; Intravenous; Topical, Intramuscular; Intravenous; Topical

prophylaxis of Bacterial endocarditis

100.0 mg/mL, , 2000.0 mg, 500.0 mg, 250.0 mg, 200.0 mg/mL, 1000.0 mg, 10000.0 mg, 100000.0 mg

, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Intramuscular, Injection, powder, for solution - Intramuscular, Powder, for solution, Powder, for solution - Intramuscular; Intravenous, Powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution, Solution - Intravenous, Kit - Intramuscular; Intravenous, Kit, Kit - Intramuscular; Intravenous; Topical, Intramuscular; Intravenous; Topical

Neisseria

100.0 mg/mL, , 2000.0 mg, 500.0 mg, 250.0 mg, 200.0 mg/mL, 1000.0 mg, 10000.0 mg, 100000.0 mg

, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intramuscular; Intravenous, Injection, powder, for solution - Intramuscular; Intravenous, Injection, solution, Injection, solution - Intravenous, Intramuscular, Injection, powder, for solution - Intramuscular, Powder, for solution, Powder, for solution - Intramuscular; Intravenous, Powder, for solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution, Solution - Intravenous, Kit - Intramuscular; Intravenous, Kit, Kit - Intramuscular; Intravenous; Topical, Intramuscular; Intravenous; Topical

Warnings

Rocephin Contraindications

Condition

Risk Level

Notes

Hyperbilirubinemia

Do Not Combine

calcium-containing IV solution requirement

Do Not Combine

There are 20 known major drug interactions with Rocephin.

Common Rocephin Drug Interactions

Drug Name

Risk Level

Description

Neomycin

Major

The risk or severity of nephrotoxicity can be increased when Ceftriaxone is combined with Neomycin.

Tenofovir

Major

Ceftriaxone may increase the nephrotoxic activities of Tenofovir.

Tenofovir alafenamide

Major

Ceftriaxone may increase the nephrotoxic activities of Tenofovir alafenamide.

Tenofovir disoproxil

Major

Ceftriaxone may increase the nephrotoxic activities of Tenofovir disoproxil.

Vibrio cholerae CVD 103-HgR strain live antigen

Major

The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Ceftriaxone.

Rocephin Toxicity & Overdose Risk

Taking too much ceftriaxone can increase the risk of kidney stones and kidney failure. Symptoms of overdose are not well known, but may be similar to the medication's side effects. If you have taken too much ceftriaxone, you should receive supportive and symptomatic care as dialysis will not reduce the drug's levels in the body.

image of a doctor in a lab doing drug, clinical research

Rocephin Novel Uses: Which Conditions Have a Clinical Trial Featuring Rocephin?

Currently, 12 active clinical trials are researching the possible utilization of Rocephin to treat Postoperative Infections, uncomplicated Bacterial Urinary Tract Infections and Whipple Disease.

Condition

Clinical Trials

Trial Phases

Whipple Disease

0 Actively Recruiting

Sinusitis

0 Actively Recruiting

Prosthetic Joint Infections

2 Actively Recruiting

Phase 4, Not Applicable

Epididymitis

0 Actively Recruiting

Postoperative Infections

0 Actively Recruiting

Abscess

0 Actively Recruiting

Conjunctivitis

0 Actively Recruiting

Intraabdominal Infections

1 Actively Recruiting

Not Applicable

Meningitis, Bacterial

0 Actively Recruiting

Otitis Media

0 Actively Recruiting

Urinary Tract Infections

0 Actively Recruiting

Community Acquired Pneumonia (CAP)

5 Actively Recruiting

Not Applicable, Phase 1, Phase 3

Gonorrhea

0 Actively Recruiting

Bacterial Infections

0 Actively Recruiting

Neisseria

0 Actively Recruiting

Arthritis, Infectious

0 Actively Recruiting

Urinary Tract Infection (UTI)

6 Actively Recruiting

Phase 1, Phase 3, Phase 4, Phase 2

prophylaxis of Postoperative Infections

0 Actively Recruiting

Osteomyelitis

0 Actively Recruiting

Vulvovaginitis

0 Actively Recruiting

Rocephin Reviews: What are patients saying about Rocephin?

5

Patient Review

11/7/2013

Rocephin for Lower Respiratory Tract Infection

This treatment always works for me. I have a very weak immune system, so this is really helpful.

5

Patient Review

11/8/2013

Rocephin for Bacterial Pneumonia caused by Haemophilus Influenzae

The relief was nearly instantaneous. I had six injections over the course of three days, and my lungs cleared up considerably. There was a lot of coughing at first, but it was worth it to get rid of the infection quickly.

5

Patient Review

3/30/2015

Rocephin for Urinary Tract Infection caused by Klebsiella Bacteria

This injection is extremely effective at quickly relieving symptoms and following up with antibiotic treatment. I highly recommend it to anyone who is suffering from a bacterial infection.

5

Patient Review

6/24/2021

Rocephin for Urinary Tract Infection caused by Klebsiella Bacteria

This antibiotic really worked when others failed. I only had to receive two shots before feeling better and the 3rd one tomorrow should be smooth sailing.

5

Patient Review

2/13/2017

Rocephin for Bacterial Pneumonia caused by Streptococcus

I was really sick for over a month, and this drug helped me feel better in just a few days. I had already tried another antibiotic, but it only worked for a little while before the symptoms came back worse than ever. Thank you so much for this medication!

5

Patient Review

1/21/2014

Rocephin for Urinary Tract Infection due to E. Coli Bacteria

I've requested Rocephin injection to treat reoccuring UTIs over the oral antibiotics specifically because it has fewer side effects (no unpleasant yeast infections or stomach issues) and have not had any problems with the shot or site of the injection itself to date. Provides relief quickly. I like it.

5

Patient Review

12/13/2012

Rocephin for Urinary Tract Infection due to E. Coli Bacteria

This shot was great! I felt relief almost immediately afterwards with no pain or side effects.

4

Patient Review

7/14/2013

Rocephin for Pneumonia caused by Bacteria

After being diagnosed with pneumonia and given two injections of Rocephin, I'm feeling much better just a few days later. The chest pain is still there, but it's manageable and my breathing is back to normal.

4

Patient Review

9/22/2022

Rocephin for Infection of Spinal Cord or Brain due to Meningococcus

I've found that Rocephin is an effective treatment for UTIs. I usually start feeling better within 48 hours of receiving the shot. Sometimes I only need one dose, but other times I have to go back to the doctor for 3 doses over 3 days. I don't find the shots painful, but then again, I have a high pain tolerance. My son had an ear infection and after 2 rounds of oral antibiotics he wasn't getting any better. But after 3 doses of Rocephin given over 3 days, he was cured. So I would definitely recommend this antibiotic!

3.7

Patient Review

1/22/2017

Rocephin for Infection of the Middle Ear caused by Streptococcus

The doctor gave me a shot of Rocephin, which wasn't painful. I started to see an improvement in my ear and sinus within two hours.

3.3

Patient Review

6/13/2015

Rocephin for Bacterial Pneumonia caused by Staphylococcus

The Rocephin shot helped me a lot when I had a very high fever. The pain was severe, but the doctor gave me a shot of lydocain beforehand, which really helped.

2.7

Patient Review

12/12/2014

Rocephin for Pneumonia caused by Bacteria

I went to the doctor thinking I had the flu, but it turned out to be negative. They gave me this shot with lidocaine, which hurt really badly. I'm still not feeling great three days later, but I am better than before. I'm not sure if the shot helped or not.

2

Patient Review

2/2/2013

Rocephin for Skin Infection due to Streptococcus Pyogenes Bacteria

I'm still experiencing some side effects even after completing the treatment.

1.7

Patient Review

12/4/2013

Rocephin for Infection of the Middle Ear caused by Streptococcus

I experienced some of the most intense pain I've ever felt, and it lasted for hours. I'm still sore today.

1.3

Patient Review

1/18/2014

Rocephin for Infection of the Middle Ear by H. Influenzae Bacteria

I've been fighting an inner ear infection for three months now, and after trying different antibiotics with no success, I decided to give this medication a shot. Unfortunately, two hours later I had a bad reaction and ended up in the emergency room. Now I'm back to square one and my ear is driving me insane!

1

Patient Review

10/16/2012

Rocephin for Pediatric Fever without a Source

Three and a half years after getting this shot, I'm still hearing impaired. My ears throb and ring all day long, 24/7. I now have to wear hearing aids because of this treatment! This all happened just an hour after getting the shot for bronchitis. My life has not been the same since then!

1

Patient Review

10/2/2013

Rocephin for Pneumonia caused by Bacteria

I had a really severe reaction to this drug that resulted in my throat closing off and me having to stay in the hospital for four days.

1

Patient Review

1/3/2014

Rocephin for Pneumonia due to the Bacteria Haemophilus Parainfluenzae

I had to be put on life support.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about rocephin

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the drug Rocephin used for?

"This medication is used to treat a wide variety of bacterial infections. It belongs to a class of drugs known as cephalosporin antibiotics. It works by stopping the growth of bacteria."

Answered by AI

Is Rocephin a strong antibiotic?

"Question: Is ceftriaxone (Rocephin) a strong antibiotic?

Ceftriaxone (Rocephin) is a "broad spectrum" antibiotic, which means that it works against a good number of bacteria. There are other antibiotics that can treat more types of infections or more serious infections."

Answered by AI

What infections does Rocephin treat?

"Infections caused by Yersinia enterocolitica and Yersinia pseudotuberculosis bacteria can lead to meningitis. Treatment to prevent meningococcal meningitis may be necessary if you are at risk for the infection. Blood infections caused by Streptococcus and Staphylococcus bacteria can also be dangerous and may require treatment."

Answered by AI

Is Rocephin the same as amoxicillin?

"Amoxicillin is used to treat gonorrhea, as well as pelvic inflammatory disease, bacterial septicemia, bone and joint infections, and meningitis. The brand names of amoxicillin include Moxatag and Amoxil, while the brand name for ceftriaxone is Rocephin."

Answered by AI

Clinical Trials for Rocephin

Image of University of Miami Health System in Miami, United States.

Antibiotic-Coated Sutures for Prosthetic Joint Infections

18 - 89
All Sexes
Miami, FL

The purpose of this study is to evaluate whether the use of antibiotic-coated (triclosan) braided sutures is non-inferior or potentially superior to standard monofilament sutures in patients with prosthetic joint infections (PJIs) managed with the DAIR protocol. Several studies in various surgical specialties have demonstrated the effectiveness and non-inferiority of triclosan-coated braided sutures in infected surgical cases, and the study intends to transpose this idea to the management of prosthetic joint infections. Monofilament sutures are the present standard of care in any infected joint case due their lower surface area for bacterial harborization, though surgeons sacrifice mechanical integrity and comfortability with the closure in the process. By demonstrating the safety of antibiotic -coated braided sutures, surgeons will no longer have to make this compromise.

Waitlist Available
Has No Placebo

University of Miami Health System

Colin McNamara, MD

Image of Preferred Primary Care Physicians, Preferred Clinical Research (Ofc 18) in Pittsburgh, United States.

VLA15 Vaccine for Lyme Disease

18 - 44
All Sexes
Pittsburgh, PA

The purpose of this study is to learn about the safety and effects of the Lyme disease vaccine (called VLA15) when given at different time points. This study is seeking participants who: * are generally healthy and between 18 and 44 years of age, * have never had a vaccine for Lyme disease before, * are not currently taking, or haven't recently taken, medicines like chemotherapy, blood products, or blood thinners, and * are not pregnant or breastfeeding and do not plan to become pregnant while receiving the study vaccine. All participants in this study will receive a total of 5 doses through a shot in the upper arm. Four doses will be the study vaccine (VLA15), and 1 dose will be saltwater. The study will compare the experiences of people receiving the study vaccine at different time points. This will help see if the study vaccine is safe and will help understand its effect on the body. Participants will take part in this study for about 2 years. During this time, the participants will have 11 planned visits - 8 will be at the study clinic and 3 will be done over the phone. The clinic visits may include having a health check, giving a small amount of blood (about 20 mL or 4 teaspoons), and getting the study vaccine or saltwater as a shot.

Phase 3
Recruiting

Preferred Primary Care Physicians, Preferred Clinical Research (Ofc 18) (+4 Sites)

Pfizer CT.gov Call Center

Pfizer

Have you considered Rocephin clinical trials?

We made a collection of clinical trials featuring Rocephin, we think they might fit your search criteria.
Go to Trials
Image of Children's Healthcare of Atlanta in Atlanta, United States.

Antibiotic Strategies for Pneumonia in Children

12 - 71
All Sexes
Atlanta, GA

The goal of this clinical trial is to determine if a "watch and wait" antibiotic strategy, called Safety Net Antibiotic Prescribing (SNAP), can safely reduce unnecessary antibiotic use while ensuring that children diagnosed with community-acquired pneumonia get better from their illness. The main aims of this study are: * To compare the effectiveness of SNAP versus immediate antibiotic prescribing in children with mild community-acquired pneumonia (CAP) * To identify which patient groups benefit most from the SNAP strategy * To identify factors that shape implementation of each prescribing strategy. Researchers will compare the SNAP strategy (where parents or guardians are instructed to give antibiotics only if their child is not improving after 72 hours, or sooner if they are worsening) to the immediate antibiotic prescribing strategy (where parents or guardians are instructed to give the antibiotics right after their healthcare visit) to see if one strategy is more effective than the other. Participants will be randomly assigned to either the immediate antibiotic group or the SNAP group at enrollment. Participation lasts 14 days with follow-up surveys at 4, 7, and 14 days after enrollment.

Recruiting
Has No Placebo

Children's Healthcare of Atlanta (+3 Sites)

Todd Florin, MD, MSCE

Image of Maternity Centre of Hamilton in Hamilton, Canada.

Rapid Test for Syphilis

13 - 49
All Sexes
Hamilton, Canada

The goal of this clinical trial is to learn if a finger-prick blood test for rapid diagnosis of syphilis infection can be implemented in a low-barrier prenatal clinic for people at risk of syphilis in pregnancy. The test gives results in 5 minutes and also tests for HIV. The main questions the study aims to answer are: * How often do pregnant people at risk of syphilis agree to the rapid test? * How well do healthcare providers perform the rapid test? * Does the rapid test speed up diagnosis and treatment of syphilis in pregnant people and their sexual partners? Participants will: * Give feedback about why they did or did not want to take the rapid test, and what their experience was taking the test; and * Share information about their health, pregnancy, and syphilis treatment (if applicable).

Recruiting
Has No Placebo

Maternity Centre of Hamilton

Laura K Erdman, MD PhD FRCPC

Have you considered Rocephin clinical trials?

We made a collection of clinical trials featuring Rocephin, we think they might fit your search criteria.
Go to Trials
Image of Harbor UCLA Medical Center - Medicine - Infectious Diseases in Torrance, United States.

Optimized Beta-lactam Dosing for Bacterial Infections

18+
All Sexes
Torrance, CA

The purpose of this study is to evaluate the abilities of Cystatin C (CysC) and CysC-based estimated Glomerular Filtration Rate (eGFR) equations to characterize the pharmacokinetics (PK) profiles of meropenem and cefepime relative to Serum Creatinine (SCR), Serum Creatinine based Equation (SCRE)and iohexol at the population and individual levels in critically ill adult patients with suspected or documented AMR Gram-negative infections. We hypothesize that CysC and CysC-based eGFR equations will characterize the PK profiles of meropenem and cefepime at the population and individual levels with greater accuracy and precision than SCR and SCREs. Iohexol will be administered to patients enrolled in the study and serve as the reference indicator of measured Glomerular Filtration Rate (mGFR), which is the gold standard assessment of kidney function. We hypothesize that the predictive performances of CysC and CysC-based eGFR equations in estimating the PK profiles of meropenem and cefepime at the population and individual levels will be comparable to iohexol. The information obtained in this study will be used to develop PK/pharmacodynamics (PD) optimized meropenem and cefepime dosing schemes based on the renal function biomarker population PK (PopPK) model with the best predictive performance for clinical use in the treatment of critically ill adult patients with suspected or documented AMR Gram-negative infections and varying degrees of renal function. The primary objective of this study is to compare the abilities of renal function biomarkers (CysC, CysC-based eGFR equations, SCR, SCREs) relative to iohexol to characterize the PK profiles of meropenem and cefepime in critically ill adult patients with suspected or documented AMR Gram-negative infections.

Phase 4
Recruiting

Harbor UCLA Medical Center - Medicine - Infectious Diseases (+9 Sites)

Image of Public Health Sexual Health Clinic in Seattle, United States.

Doxycycline for Syphilis

18+
All Sexes
Seattle, WA

The goal of this clinical trial is to learn if doxycycline taken as 200mg daily for 14 days is effective to treat early stage syphilis. This is different from how doxycycline is typically used for syphilis because the full doxycycline dose will be taken at the same time of day, rather than split up into a twice daily regimen. Lab data support that taking the medication as a single daily dose should be effective as treatment, but it has not been studied clinically. The main question this study aims to answer is: Is doxycycline taken as a single daily dose of 200mg for 14 days an effective treatment for early syphilis based on a combined outcome of clinical improvement and blood test improvement? Participants will: 1. Take doxycycline 200mg daily for 14 days 2. Submit oral and rectal swabs that test for syphilis bacteria every other day for 2 weeks, returned by mail 3. Complete 2 brief online surveys over the first 2 weeks 4. Return to the clinic for an interview and blood draw every 3 months for a maximum of 3 study visits, including the first visit The investigators will compare the percentage of participants in the study who have response to treatment by 6 months to that of persons who have received standard (CDC-recommended) regimens. To do this, the investigators will calculate response percentage estimates following a shot of long-acting penicillin or 14 days of doxycycline 100mg twice daily from 60-person samples from the sexual health program's records.

Phase 2
Recruiting

Public Health Sexual Health Clinic

Travis Hunt, MD

Have you considered Rocephin clinical trials?

We made a collection of clinical trials featuring Rocephin, we think they might fit your search criteria.
Go to Trials