Rimso-50
extravasation of chemotherapy drugs, Cystitis, Interstitial
Treatment
0 Active Studies for Rimso-50
Treatment for
extravasation of chemotherapy drugs
What is Rimso-50
Dimethyl sulfoxide
The Generic name of this drug
Treatment Summary
Dimethyl sulfoxide is a chemical solvent used in many industries, including pharmaceuticals. It is a liquid that can pass through biological membranes, making it useful for topical applications. It is also used to preserve tissue during cryopreservation and has been shown to have analgesic and anti-inflammatory effects.
Rimso-50
is the brand name
Rimso-50 Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Rimso-50
Dimethyl sulfoxide
1978
1
Effectiveness
How Rimso-50 Affects Patients
Dimethyl Sulfoxide may reduce inflammation, fight off harmful substances, and provide pain relief. It can also help other substances to get through the skin more easily, and so is sometimes used in combination with idoxuridine to treat herpes zoster in the UK.
How Rimso-50 works in the body
The exact way dimethyl sulfoxide works is a mystery. However, it may protect your heart from damage and reduce inflammation by acting as an antioxidant.
When to interrupt dosage
The measure of Rimso-50 is connected to the indicated condition. The amount of dosage fluctuates in correlation to the delivery method featured in the table beneath.
Condition
Dosage
Administration
extravasation of chemotherapy drugs
, 540.0 mg/mL, 70.0 %, 0.5 mg/mg
, Intravesical, Irrigant - Intravesical, Irrigant, Solution - Intravesical, Solution, Topical, Solution - Topical
Cystitis, Interstitial
, 540.0 mg/mL, 70.0 %, 0.5 mg/mg
, Intravesical, Irrigant - Intravesical, Irrigant, Solution - Intravesical, Solution, Topical, Solution - Topical
Warnings
Rimso-50 Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Rimso-50.
Common Rimso-50 Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be decreased when combined with Dimethyl sulfoxide.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be decreased when combined with Dimethyl sulfoxide.
Alectinib
Major
The metabolism of Alectinib can be decreased when combined with Dimethyl sulfoxide.
Alpelisib
Major
The metabolism of Alpelisib can be decreased when combined with Dimethyl sulfoxide.
Aminophylline
Major
The metabolism of Aminophylline can be decreased when combined with Dimethyl sulfoxide.
Rimso-50 Toxicity & Overdose Risk
The amount of dimethyl sulfoxide needed to be toxic to dogs is greater than 10 gm/kg, which would be impossible to reach through intravesical instillation in humans.
Rimso-50 Novel Uses: Which Conditions Have a Clinical Trial Featuring Rimso-50?
16 active trials are investigating the potential of Rimso-50 to counter the extravasation of chemotherapy drugs.
Condition
Clinical Trials
Trial Phases
extravasation of chemotherapy drugs
0 Actively Recruiting
Cystitis, Interstitial
0 Actively Recruiting
Rimso-50 Reviews: What are patients saying about Rimso-50?
1
Patient Review
7/6/2008
Rimso-50 for Bladder Wall Inflammation
Patient Q&A Section about rimso-50
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
How much does RIMSO-50 cost?
"Rimso-50 irrigation solution 50% costs approximately $661 for 50 milliliters, depending on the pharmacy. This price is only for cash paying customers and not valid with insurance plans."
Answered by AI
What does DMSO do for the bladder?
"Dimethyl sulfoxide is a bladder medication used to treat pain and discomfort caused by interstitial cystitis. This medication may also be used for other purposes; please consult your health care provider or pharmacist with any questions."
Answered by AI
What is Rimso instillation?
"The following text describes how to instill RIMSO-50 into the bladder. To do this, a catheter or asepto syringe can be used. The person carrying out the procedure should first apply an analgesic lubricant gel to the urethra, in order to avoid spasm. Then, 50 mL of RIMSO-50 should be instilled directly into the bladder, and allowed to remain there for 15 minutes."
Answered by AI
What is RIMSO-50 used for?
"This medication, Dimethyl sulfoxide, is used to treat a certain bladder condition known as interstitial cystitis. It is believed to work by reducing swelling and pain due to interstitial cystitis and may also improve blood supply to the treated area."
Answered by AI