Rhinocort

Proteinuria, Asthma, Itching + 16 more

Treatment

20 Active Studies for Rhinocort

Treatment for

Proteinuria

What is Rhinocort

Budesonide

The Generic name of this drug

Treatment Summary

Budesonide is a steroid used to treat various types of inflammation, such as asthma, COPD, Crohn's disease, and ulcerative colitis. It was approved by the FDA in 1994 and is available in both oral and inhaled forms.

Rhinocort

is the brand name

image of different drug pills on a surface

Rhinocort Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Rhinocort

Budesonide

1994

134

Effectiveness

How Rhinocort Affects Patients

Budesonide is a medication used to help reduce inflammation in respiratory and digestive issues. The dose of budesonide needed varies from person to person, so it is important for patients to discuss their individual risks of developing high levels of cortisol (hypercorticism) or suppressing the adrenal axis.

How Rhinocort works in the body

Corticosteroids are a type of medication that reduce inflammation. They work by binding to special receptors in the body and changing how genes are expressed. This causes several effects, such as blocking white blood cells from flowing to sites of inflammation and decreasing the production of molecules that cause inflammation. Lower doses of corticosteroids reduce inflammation, while higher doses can suppress the immune system. Over time, these higher doses can also affect levels of sodium and potassium in the body.

When to interrupt dosage

The proposed dosage of Rhinocort is contingent upon the diagnosed sickness, encompassing Vasomotor Rhinitis, Crohn's Disease and Chronic Obstructive Pulmonary Disease (COPD). The quantity of dosage is contingent upon the technique of administration (e.g. Enema; Kit; Tablet - Rectal or Respiratory (inhalation)) as noted in the table below.

Condition

Dosage

Administration

Crohn Disease

, 0.25 mg/mL, 0.5 mg/mL, 1.0 mg/mL, 0.09 mg, 0.032 mg, 3.0 mg, 0.18 mg, 0.2 mg, 0.5 mg, 9.0 mg, 28.0 mg, 2.3 mg, 0.08 mg, 0.16 mg, 0.00008 mg/hour, 0.32 mg, 1.0 mg, 6.0 mg, 0.125 mg/mL, 4.0 mg, 0.064 mg/pump actuation, 0.4 mg/pump actuation, 0.1 mg/pump actuation, 2.0 mg/pump actuation, 0.2 mg/pump actuation, 0.182 mg/pump actuation

Respiratory (inhalation), Inhalant, , Inhalant - Respiratory (inhalation), Suspension, Suspension - Respiratory (inhalation), Aerosol, powder, Aerosol, powder - Respiratory (inhalation), Spray, metered, Nasal, Spray, metered - Nasal, Powder - Respiratory (inhalation), Powder, Aerosol, foam, Aerosol, foam - Rectal, Rectal, Capsule, delayed release pellets - Oral, Capsule, delayed release pellets, Tablet, extended release, Tablet, extended release - Oral, Enema; Kit; Tablet, Enema; Kit; Tablet - Rectal, Capsule, extended release - Oral, Capsule, extended release, Capsule, coated pellets - Oral, Nasal; Respiratory (inhalation), Aerosol - Respiratory (inhalation), Aerosol, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Oral, Inhalant - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Powder, metered, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Capsule - Oral, Capsule, Cutaneous, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Kit, Powder, metered - Respiratory (inhalation), Powder - Nasal; Respiratory (inhalation), Aerosol, metered - Nasal, Capsule, coated pellets, Kit - Rectal, Capsule, delayed release - Oral, Capsule, delayed release, Patch - Cutaneous, Patch

Colitis, Collagenous

Proteinuria

Nasal Congestion

Asthma

Itching

Skin Diseases

Acute Coryza

Ulcerative Colitis

Rhinitis, Vasomotor

Nasal Polyps

Crohn's Disease

Eosinophilic Esophagitis

Hypersensitivity

IGA Glomerulonephritis

Sinusitis

Crohn Disease

maintenance therapy

Chronic Obstructive Pulmonary Disease

Warnings

Rhinocort has five contraindications and should be avoided if you encounter any of the conditions in the following table.

Rhinocort Contraindications

Condition

Risk Level

Notes

Asthma

Do Not Combine

Severe Hepatic Impairment

Do Not Combine

Status Asthmaticus

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Budesonide may interact with Pulse Frequency

Severe Hypersensitivity Reactions

Do Not Combine

Budesonide may interact with Pulse Frequency

There are 20 known major drug interactions with Rhinocort.

Common Rhinocort Drug Interactions

Drug Name

Risk Level

Description

2-Methoxyethanol

Major

The risk or severity of adverse effects can be increased when Budesonide is combined with 2-Methoxyethanol.

9-(N-methyl-L-isoleucine)-cyclosporin A

Major

The risk or severity of adverse effects can be increased when Budesonide is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.

Abatacept

Major

The risk or severity of adverse effects can be increased when Budesonide is combined with Abatacept.

Abemaciclib

Major

The metabolism of Abemaciclib can be increased when combined with Budesonide.

Abetimus

Major

The risk or severity of adverse effects can be increased when Budesonide is combined with Abetimus.

Rhinocort Toxicity & Overdose Risk

It is uncommon for someone to experience an acute overdose of corticosteroids, but taking them in high doses for an extended period of time can cause an excess of the hormones and suppress the adrenal axis. If an overdose does occur, the dosage of corticosteroids should be reduced temporarily. 200mg of corticosteroids is fatal for female mice and 400mg is fatal for male mice.

image of a doctor in a lab doing drug, clinical research

Rhinocort Novel Uses: Which Conditions Have a Clinical Trial Featuring Rhinocort?

516 active trials are assessing the potential of Rhinocort to ameliorate Chronic Obstructive Pulmonary Disease (COPD), Ulcerative Colitis and Allergic symptoms.

Condition

Clinical Trials

Trial Phases

Asthma

87 Actively Recruiting

Phase 1, Phase 4, Early Phase 1, Not Applicable, Phase 2, Phase 3

Itching

3 Actively Recruiting

Phase 3, Not Applicable

Chronic Obstructive Pulmonary Disease

72 Actively Recruiting

Phase 3, Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 4

Proteinuria

5 Actively Recruiting

Phase 2, Phase 3, Phase 4, Phase 1

IGA Glomerulonephritis

0 Actively Recruiting

Ulcerative Colitis

17 Actively Recruiting

Phase 3, Phase 2, Phase 1, Not Applicable, Phase 4

Sinusitis

0 Actively Recruiting

Crohn's Disease

53 Actively Recruiting

Phase 1, Phase 2, Not Applicable, Phase 3, Phase 4, Early Phase 1

Hypersensitivity

1 Actively Recruiting

Phase 4

Colitis, Collagenous

0 Actively Recruiting

Skin Diseases

0 Actively Recruiting

maintenance therapy

0 Actively Recruiting

Rhinitis, Vasomotor

1 Actively Recruiting

Not Applicable

Eosinophilic Esophagitis

0 Actively Recruiting

Acute Coryza

0 Actively Recruiting

Crohn Disease

0 Actively Recruiting

Nasal Polyps

0 Actively Recruiting

Crohn Disease

0 Actively Recruiting

Nasal Congestion

0 Actively Recruiting

Rhinocort Reviews: What are patients saying about Rhinocort?

Patient Review

4/28/2013

Rhinocort for Allergic Rhinitis Prevention

I've found this treatment to be effective and much gentler on my nose than Flonase, which would sometimes give me bloody noses.

Patient Review

10/11/2016

Rhinocort for Allergic Rhinitis Prevention

Rhinocort is vastly superior to Flonase in my opinion. It doesn't gave me headaches, and the effects last much longer throughout the day. I also don't have any issues with taste or dryness, which were both common problems I had when using Flonase.

Patient Review

12/23/2010

Rhinocort for Inflammation of the Nose due to an Allergy

I experience dizziness when using this product; however, it has helped to reduce the inflammation I was experiencing.

Patient Review

10/11/2016

Rhinocort for Allergic Rhinitis Prevention

I've had allergies my whole life, and this nasal spray is by far the best option I've found.

Patient Review

7/4/2017

Rhinocort for Inflammation of the Nose due to an Allergy

I've been using this product for a while now and it has definitely made a difference for me. I used to have to take allergy shots twice a week, but this spray has worked so well that I don't need them anymore.

Patient Review

4/28/2010

Rhinocort for Inflammation of the Nose due to an Allergy

4.3

Patient Review

10/31/2014

Rhinocort for Inflammation of the Nose due to an Allergy

I've been using this medication for four months as recommended by my doctor. I can definitely see a positive effect; my sinuses have improved and I experience less nosebleeds. Plus, my allergies don't seem to be as bad as they used to be.

Patient Review

3/15/2016

Rhinocort for Allergic Rhinitis Prevention

I've only been using this for a short while, but it's already miles ahead of the nasalcort I tried previously. That gave me nasty nosebleeds, whereas this has no bad aftertaste and seems to be working quite well. I stick to one spray per nostril to avoid any potential nosebleeds, and so far that's been fine.

Patient Review

4/16/2013

Rhinocort for Allergic Rhinitis Prevention

I noticed a significant difference in my breathing after only a few days of using this product.

2.3

Patient Review

4/13/2020

Rhinocort for Inflammation of the Nose due to an Allergy

Long-term use of this drug is dangerous. I realized what was happening to me after two years: mild asthma, anxiety, wheezing, and heel pain in both legs. I stopped using the drug for a few days and saw an immediate relief.

1.7

Patient Review

7/22/2018

Rhinocort for Chronic Inflammation of the Nose Not due to Allergies

Unfortunately, this was the only nasal spray that made me feel more congested after using it.

1.7

Patient Review

4/19/2010

Rhinocort for Allergic Rhinitis Prevention

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about rhinocort

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Rhinocort being discontinued?

"is the last updated date for the Rhinocort brand name. If the FDA has approved generic versions of this product, then there may be generic equivalents available."

Answered by AI

Is Rhinocort the same as Flonase?

"Rhinocort and Flonase are two corticosteroid medications that can treat allergy symptoms. Flonase is more potent than Rhinocort, however they are both effective at reducing inflammation and treating symptoms such as a stuffy or itchy nose, and watery eyes."

Answered by AI

What is Rhinocort used to treat?

"Rhinocort Aqua is a steroid nasal spray used to treat Nasal Congestion, Sneezing, Runny Nose, and nasal polyps caused by allergies."

Answered by AI

What is better Rhinocort or Nasonex?

"Nasonex (Mometasone) and Rhinocort Aqua (Budesonide) are both good options for treating a stuffy or runny nose caused by allergies. Nasonex relieves nasal allergy symptoms and is a good first choice for treatment. Rhinocort Aqua is a steroid nasal spray that works best when used regularly."

Answered by AI

Clinical Trials for Rhinocort

Have you considered Rhinocort clinical trials?

We made a collection of clinical trials featuring Rhinocort, we think they might fit your search criteria.

Have you considered Rhinocort clinical trials?

We made a collection of clinical trials featuring Rhinocort, we think they might fit your search criteria.

Image of Stanford University in Stanford, United States.

MoblO2 for Chronic Lung Diseases

18+

All Sexes

Stanford, CA

Many patients with chronic lung disease (e.g., chronic obstructive pulmonary disease (COPD) or interstitial lung disease (ILD)) require supplemental oxygen (O2) at some point during their disease course. Practitioners prescribe O2 to patients with chronic lung disease in hopes of the following: 1) that it will limit desaturation events and combat breathlessness, thus preventing the frustratingly slow pace and numerous rest breaks patients are forced to adopt while doing even simple tasks; 2) that it will allow patients to be more active physically (perhaps increase their ability to exercise) and socially (perhaps leave the home more often); 3) that it will stave off putative complications of hypoxemia (e.g., cognitive dysfunction, pulmonary hypertension) and 4) that it will improve health-related quality of life (HRQL). However, despite the rationale for O2, and prescribers' good intentions, patients generally view O2 with frustration and fear - it threatens their HRQL, which is already impaired by having a condition that imposes itself on every aspect of their lives. Nasal cannulas and delivery devices call unwanted attention to patients when they are out in public. O2 users feel stigmatized and are often viewed as "smokers who get what they deserve, even if they never smoked a day in their lives" - or as disabled, sick or even infectious. O2 steals patients' independence, forcing them to plan their lives around it. The anxiety that patients and their caregivers experience around running out of oxygen, or not getting enough, immobilizes them and restricts participation in activities outside of the home. O2 disrupts the home environment, adding stress, and creating a burden for patients' caregiver-loved-ones who are often saddled with the responsibility of ensuring adequate equipment and supply of O2, and O2 is a constant reminder to patients they are living with a condition that could shorten their lives. O2 delivery equipment is typically heavy, unwieldy and intimidating. Different recommendations (e.g., insurance companies use 88% as a cut-off for SpO2, while many practitioners focus on 90%) make it confusing for patients, which almost certainly affects adherence. O2-requiringpatients are starving for things that can make their lives easier. An auto-adjusting O2 delivery device - one that automatically delivers the correct amount of O2 to maintain blood oxygen at desired, pre-set levels - would alleviate the need for patients to constantly (incessantly for many) monitor their peripheral oxygen saturation (SpO2) and adjust O2flow to meet the demands as exertion levels vary . The MoblO2 device is a battery-operated, light-weight, closed-loop O2 delivery device that houses a regulator (which attaches to compressed gas O2 tanks) and adjusts O2 flow to meet a pre-set blood oxygen level. A pulse oximeter is worn on the ear and transmits via Bluetooth to the device, which adjusts an internal valve to control flow on a second-to-second basis. The user sets the dial to the highest flow of O2 needed to meet the demands of activities they might perform (up to 15 liters per minute), and the device adjusts flow, up to the pre-set level to maintain SpO2 at a preset level (e.g., \> 90%). To conserve O2 supply in the tank - and to avoid over-oxygenation (which could be problematic for a small percentage of patients with the most severe COPD) - the MoblO2 begins to limit O2 flow at a SpO2 of 93%. The device can be manually over-ridden by the user, and should the battery run out - or the device fail for some unforeseen reason - the default position is valve open, so the users receive whatever flow of oxygen has been set on the dial. Given the substantial burdens of O2 on patients and their families, the hassles patients describe with having to monitor their SpO2 and repeatedly adjust the flow of O2 to meet their needs, patients and experts around the world have called for improvements in O2 delivery equipment. The MoblO2 is just such a remarkable improvement and a giant step forward in helping to ease the burdens of O2 on patients who require it. The purpose of this study is to investigate the effects of the MoblO2 O2 delivery device on a range of outcomes, including physical activity, amount (liters) O2 use; maintenance of adequate SpO2 levels; patient reported outcomes including symptoms, HRQL and satisfaction with the MoblO2 O2 device.

Waitlist Available

Has No Placebo

Stanford University

Jeff Swigris, DO, MS

Minnesota Health Solutions