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Surgery vs Stereotactic Radiotherapy for Lung Cancer (VALOR Trial)
VALOR Trial Summary
This trial is testing whether surgery or stereotactic radiotherapy is better for people with stage I non-small cell lung cancer.
VALOR Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowVALOR Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.VALOR Trial Design
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Who is running the clinical trial?
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- I am considered fit for lung surgery that is not a wedge resection.I have had cancer before, but it wasn't follicular lymphoma, chronic lymphocytic leukemia, or hormone-sensitive prostate cancer.I am a woman under 61 or haven't had a hysterectomy and my pregnancy test is positive.I am 18 years old or older.I have or am suspected to have early-stage lung cancer.I am willing and able to agree to participate in the study.My tumor is at least 1cm away from critical areas like the windpipe or spinal cord.My cancer has spread to my lymph nodes or other parts of my body.My lung cancer diagnosis was confirmed through a biopsy.My case has been reviewed by a team of different healthcare specialists.My tumor is 5cm or smaller, based on my latest scans.My lymph nodes larger than 10mm with high activity were checked.I must have a biopsy if there are suspicious lesions on my PET/CT scan.My cancer has spread to my lymph nodes or other parts of my body.My primary tumor is 5 cm or smaller, confirmed by a CT scan.I have been diagnosed with stage IV cancer.I have a history of scleroderma.I have had lung cancer before, but not including my current condition.A radiation oncologist has approved me for a specific type of targeted radiotherapy.I had cancer treatment within the last 2 years, but not for low-risk cancers.Your lung function tests show that you can breathe out at least 40% of what is expected and your lungs can transfer oxygen at least 40% as expected.A thoracic surgeon has deemed me inoperable.I am able to care for myself but may not be able to do active work.I had a PET/CT scan within the last 60 days.I have had surgery for lung, esophageal cancer, or heart surgery before.I am willing to be assigned to a treatment group by chance.I have had radiation therapy to my chest area before.
- Group 1: Stereotactic radiotherapy
- Group 2: Surgery
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Are there currently any openings for enrolment in this trial?
"Affirmative. Clinicaltrials.gov documents corroborate that this investigation is actively accruing participants from 16 different medical centres, since it was published on April 13th 2017 and last edited September 9th 2022. The trial requires 670 enrollees in total."
How many people have participated in the trial thus far?
"To conduct this clinical trial, 670 individuals who qualify for the established criteria must partake. These patients can visit two different locations: VA Greater Los Angeles Healthcare System in West Los Angeles and Michael E. DeBakey VA Medical Center in Houston, TX."
How many healthcare facilities are conducting this experiment?
"This medical trial is accepting patients at VA Greater Los Angeles Healthcare System in West Los Angeles, California; Michael E. DeBakey VA Medical Center in Houston, Texas; and VA Long Beach Healthcare System in Long Beach, Massachusetts; with additional sites located across the country."
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