What is Reyataz
AtazanavirThe Generic name of this drug
Treatment SummaryAtazanavir (formerly known as BMS-232632) is a medication used to treat HIV infection. It is part of a class of drugs called protease inhibitors. Atazanavir is different from other protease inhibitors as it only needs to be taken once a day and has less of an effect on the patient's cholesterol levels. It is always used with other HIV medications. The FDA approved atazanavir in 2003.
Reyatazis the brand name
Reyataz Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Reyataz
Atazanavir
2003
63
Effectiveness
How Reyataz Affects PatientsAtazanavir is a drug that works against Human Immunodeficiency Virus Type 1 (HIV-1). It blocks an enzyme called HIV-1 protease, which is necessary for the virus to form and spread. Atazanavir should be used with other anti-HIV drugs in order to be effective. It is similar but different from other protease inhibitors and other antiretroviral drugs currently available.
How Reyataz works in the bodyAtazanavir targets the HIV-1 virus and stops it from forming mature virions. It does this by blocking the active site of the HIV-1 protease, which is responsible for the processing of the virus' proteins. Atazanavir does not work against the HIV-2 virus.
When to interrupt dosage
The proposed dosage of Reyataz is predicated upon the determined condition, including weight of at least 35 kg, Antiretroviral Therapy and HIV (Human Immunodeficiency Virus). The measure of dosage is contingent upon the form of administration (e.g. Tablet, film coated or Oral) featured in the table below.Condition
Dosage
Administration
weight at least 35 kg
150.0 mg, , 200.0 mg, 100.0 mg, 50.0 mg, 300.0 mg
Tablet, film coated, Oral, Powder - Oral, , Capsule, gelatin coated - Oral, Capsule - Oral, Tablet, Capsule, gelatin coated, Tablet, film coated - Oral, Capsule, Tablet - Oral, Powder
Antiretroviral Therapy
150.0 mg, , 200.0 mg, 100.0 mg, 50.0 mg, 300.0 mg
Tablet, film coated, Oral, Powder - Oral, , Capsule, gelatin coated - Oral, Capsule - Oral, Tablet, Capsule, gelatin coated, Tablet, film coated - Oral, Capsule, Tablet - Oral, Powder
HIV
150.0 mg, , 200.0 mg, 100.0 mg, 50.0 mg, 300.0 mg
Tablet, film coated, Oral, Powder - Oral, , Capsule, gelatin coated - Oral, Capsule - Oral, Tablet, Capsule, gelatin coated, Tablet, film coated - Oral, Capsule, Tablet - Oral, Powder
Warnings
Reyataz has nineteen contraindications, and its use should be avoided where any of the conditions in the following table are present.Reyataz ContraindicationsCondition
Risk Level
Notes
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
Common Reyataz Drug Interactions
Drug Name
Risk Level
Description
(R)-warfarin
Major
The metabolism of (R)-warfarin can be decreased when combined with Atazanavir.
(S)-Warfarin
Major
The metabolism of (S)-Warfarin can be decreased when combined with Atazanavir.
1,2-Benzodiazepine
Major
The metabolism of 1,2-Benzodiazepine can be decreased when combined with Atazanavir.
3,5-diiodothyropropionic acid
Major
The metabolism of 3,5-diiodothyropropionic acid can be decreased when combined with Atazanavir.
5-androstenedione
Major
The metabolism of 5-androstenedione can be decreased when combined with Atazanavir.
Reyataz Novel Uses: Which Conditions Have a Clinical Trial Featuring Reyataz?
44 active trials are in progress to investigate the utility of Reyataz in treating HIV (Human Immunodeficiency Virus) and Antiretroviral Therapy in individuals of weight at least 35 kg.Condition
Clinical Trials
Trial Phases
weight at least 35 kg
0 Actively Recruiting
HIV
50 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 1, Phase 4, Early Phase 1
Antiretroviral Therapy
1 Actively Recruiting
Phase 3
Reyataz Reviews: What are patients saying about Reyataz?
5Patient Review
9/19/2009 I've been on this medication for five years now. When I first started, the side effects were really bad (vomiting and diarrhea for about three weeks). But I haven't had any problems since then.
5Patient Review
4/2/2013 I've been taking Reyataz and Epzicom for four years now with excellent results. I take it every night with dinner and have had no negative side effects that I can tell. My T-cells have increased from 480 to 1000 in that time, and other measures like my lipids have stayed good too.
5Patient Review
3/8/2008 I didn't experience any negative side effects from this treatment, except for some unwanted weight gain in my midsection.
5Patient Review
5/15/2009 I've been using this medication for a while now and I haven't experienced any negative side effects. I'm very pleased with it overall.
5Patient Review
7/30/2008 I've been on Reyataz for almost three years now, and it's by far the best protease inhibitor I've ever taken. I highly recommend it to anyone who is looking for a new lease on life.
5Patient Review
3/24/2009 It's crucial that you take your HIV medication as prescribed in order to maintain your health.
5Patient Review
11/25/20074.7Patient Review
9/21/2011 This medication has been a great help in my overall treatment program.
4.3Patient Review
7/12/2010 I frequently feel exhausted.
4.3Patient Review
9/18/2009 I switched from Trizivir/Kaletra to Reyataz/Epzicom, but my liver enzymes quadrupled as a result (I don't have Hep A,B,C, and I don't drink alcohol). The new regimen also led to a different type of fatigue. Two months into the new regimen, there has only been a nominal improvement. It seems like the choices are either high cholesterol or liver damage.
4.3Patient Review
6/11/2009 The side effects are worse than they explained
1Patient Review
12/26/2007 This drug had no effect on me whatsoever. I have a very high tolerance for drugs.
Patient Q&A Section about reyataz
Is there a generic for Reyataz?
"Teva Pharmaceuticals has announced the launch of a generic version of the drug Reyataz in the United States. The drug is indicated for use in combination with other antiretroviral agents, and acts as a protease inhibitor for the treatment of HIV-1 infection in patients six years of age and older weighing at least 15 kg." - Anonymous Online Contributor
Unverified Answer
What are the side effects of Reyataz?
"If you experience any of the following symptoms, you may be suffering from the flu: nausea, headache, stomach-area pain, vomiting, trouble sleeping, numbness, tingling, or burning of hands or feet, dizziness, muscle pain." - Anonymous Online Contributor
Unverified Answer
What is Reyataz used for?
"This drug is used in conjunction with other HIV medications to help control the spread of the virus. By decreasing the amount of HIV in the body, it allows the immune system to function more effectively, lowering the chances of developing complications such as new infections or cancer, and improving the patient's quality of life." - Anonymous Online Contributor
Unverified Answer
Who manufactures Reyataz?
"Teva Pharmaceuticals has announced that it will be the exclusive manufacturer of a generic version of the brand-name antiretroviral (ARV) medication Reyataz (atazanavir). Reyataz is approved for use in combination with two or more other ARVs to treat HIV." - Anonymous Online Contributor
Unverified Answer