Propranolol Hydrochloride

Thyroid Crisis, Atrial Fibrillation, Migraine + 23 more

Treatment

5 FDA approvals

20 Active Studies for Propranolol Hydrochloride

What is Propranolol Hydrochloride

Propranolol

The Generic name of this drug

Treatment Summary

Propranolol is a medication used to treat high blood pressure. It is a combination of two enantiomers, one of which binds to beta-adrenergic receptors much more strongly than the other. Propranolol has been approved by the FDA since 1967 and is generally safe and effective for its intended use.

Inderal

is the brand name

image of different drug pills on a surface

Propranolol Hydrochloride Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Inderal

Propranolol

1967

471

Approved as Treatment by the FDA

Propranolol, also known as Inderal, is approved by the FDA for 5 uses including Obstructive Hypertrophic Cardiomyopathy and Tremor, Essential .

Obstructive Hypertrophic Cardiomyopathy

Tremor, Essential

Helps manage Tremor, Essential

Essential Tremor

Helps manage Tremor, Essential

Cardiomyopathy, Hypertrophic

Hypertensive disease

Used to treat High Blood Pressure (Hypertension) in combination with Hydrochlorothiazide

Effectiveness

How Propranolol Hydrochloride Affects Patients

Propranolol is a drug used to treat high blood pressure. It usually only needs to be taken once or twice a day. Suddenly stopping propranolol can cause chest pain and heart attack-like symptoms.

How Propranolol Hydrochloride works in the body

Propranolol blocks beta-receptors, which are involved in blood vessel growth and constriction. Blocking these receptors can decrease the growth of new blood vessels, reduce the activity of a hormone system involved in blood pressure regulation, and induce apoptosis in certain types of cells.

When to interrupt dosage

The suggested measure of Propranolol Hydrochloride is contingent upon the recognized disorder, including Catecholamines, Hypertensive disease and Hemangiomas. The quantity of dosage deviates as per the mode of delivery (e.g. Solution - Oral or Capsule, extended release - Oral) mentioned in the table below.

Condition

Dosage

Administration

Adrenergic Alpha-Antagonists

, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL

, Intravenous, Injection, Injection - Intravenous, Capsule, extended release, Capsule, extended release - Oral, Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral

Heart Attack

, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL

, Intravenous, Injection, Injection - Intravenous, Capsule, extended release, Capsule, extended release - Oral, Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral

Tachyarrhythmia caused by Digitalis intoxication

, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL

, Intravenous, Injection, Injection - Intravenous, Capsule, extended release, Capsule, extended release - Oral, Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral

Psychomotor Agitation

, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL

, Intravenous, Injection, Injection - Intravenous, Capsule, extended release, Capsule, extended release - Oral, Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral

Tremor

, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL

, Intravenous, Injection, Injection - Intravenous, Capsule, extended release, Capsule, extended release - Oral, Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral

Thyrotoxicosis

, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL

, Intravenous, Injection, Injection - Intravenous, Capsule, extended release, Capsule, extended release - Oral, Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral

Chest Pain

, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL

, Intravenous, Injection, Injection - Intravenous, Capsule, extended release, Capsule, extended release - Oral, Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral

Supraventricular Arrhythmias

, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL

, Intravenous, Injection, Injection - Intravenous, Capsule, extended release, Capsule, extended release - Oral, Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral

Hemangioma

, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL

, Intravenous, Injection, Injection - Intravenous, Capsule, extended release, Capsule, extended release - Oral, Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral

Cardiomyopathy, Hypertrophic

, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL

, Intravenous, Injection, Injection - Intravenous, Capsule, extended release, Capsule, extended release - Oral, Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral

Proliferating Infantile Hemangioma

, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL

, Intravenous, Injection, Injection - Intravenous, Capsule, extended release, Capsule, extended release - Oral, Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral

Hypertensive disease

, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL

, Intravenous, Injection, Injection - Intravenous, Capsule, extended release, Capsule, extended release - Oral, Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral

Performance Anxiety

, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL

, Intravenous, Injection, Injection - Intravenous, Capsule, extended release, Capsule, extended release - Oral, Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral

Pheochromocytoma

, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL

, Intravenous, Injection, Injection - Intravenous, Capsule, extended release, Capsule, extended release - Oral, Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral

Ventricular Tachycardia

, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL

, Intravenous, Injection, Injection - Intravenous, Capsule, extended release, Capsule, extended release - Oral, Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral

Migraine

, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL

, Intravenous, Injection, Injection - Intravenous, Capsule, extended release, Capsule, extended release - Oral, Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral

Gastroesophageal variceal hemorrhage prophylaxis

, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL

, Intravenous, Injection, Injection - Intravenous, Capsule, extended release, Capsule, extended release - Oral, Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral

Catecholamines

, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL

, Intravenous, Injection, Injection - Intravenous, Capsule, extended release, Capsule, extended release - Oral, Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral

Migraine Disorders

, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL

, Intravenous, Injection, Injection - Intravenous, Capsule, extended release, Capsule, extended release - Oral, Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral

Atrial Fibrillation

, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL

, Intravenous, Injection, Injection - Intravenous, Capsule, extended release, Capsule, extended release - Oral, Oral, Tablet, Tablet - Oral, Injection, solution, Injection, solution - Intravenous, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral

Warnings

Propranolol Hydrochloride Contraindications

Condition

Risk Level

Notes

Heart Decompensation

Do Not Combine

Bronchial Spasm

Do Not Combine

Asthma

Do Not Combine

Infants Weighing <2kg

Do Not Combine

Low Blood Pressure

Do Not Combine

Sick Sinus Syndrome

Do Not Combine

Asthma

Do Not Combine

Pheochromocytoma

Do Not Combine

Atrioventricular Block

Do Not Combine

Slow Heart Rate

Do Not Combine

Shock, Cardiogenic

Do Not Combine

Heart Decompensation

Do Not Combine

Prematurity

Do Not Combine

Sinus Bradycardia

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Propranolol may interact with Pulse Frequency

There are 20 known major drug interactions with Propranolol Hydrochloride.

Common Propranolol Hydrochloride Drug Interactions

Drug Name

Risk Level

Description

4-Bromo-2,5-dimethoxyphenethylamine

Major

The therapeutic efficacy of 4-Bromo-2,5-dimethoxyphenethylamine can be decreased when used in combination with Propranolol.

4-Methoxyamphetamine

Major

The therapeutic efficacy of 4-Methoxyamphetamine can be decreased when used in combination with Propranolol.

Abediterol

Major

Propranolol may decrease the bronchodilatory activities of Abediterol.

Adrafinil

Major

The therapeutic efficacy of Adrafinil can be decreased when used in combination with Propranolol.

Agrostis gigantea pollen

Major

The risk of a hypersensitivity reaction to Agrostis gigantea pollen is increased when it is combined with Propranolol.

Propranolol Hydrochloride Toxicity & Overdose Risk

Overdosing on propranolol can lead to low blood pressure, seizures from low blood sugar, restlessness, and difficulty sleeping. Asthmatic individuals may experience bronchospasm. To treat an overdose, monitor vital signs, mental state, and blood sugar levels. Low blood pressure can be treated with intravenous fluids, bradycardia with atropine and isoproterenol, and bronchospasm with aminophylline. If these treatments are ineffective, glucagon should be given intravenously followed by catecholamines. Dialysis will not be effective as propranolol is strongly bound

image of a doctor in a lab doing drug, clinical research

Propranolol Hydrochloride Novel Uses: Which Conditions Have a Clinical Trial Featuring Propranolol Hydrochloride?

249 active trials are currently being conducted to assess the effectiveness of Propranolol Hydrochloride in reducing the symptoms of Migraine, Catecholamines and Hypertensive Disease.

Condition

Clinical Trials

Trial Phases

Atrial Fibrillation

94 Actively Recruiting

Not Applicable, Phase 2, Phase 4, Phase 1, Phase 3, Early Phase 1

Heart Attack

23 Actively Recruiting

Not Applicable, Phase 1, Phase 4, Phase 2, Early Phase 1, Phase 3

Coronary Artery Disease

1 Actively Recruiting

Not Applicable

Chest Pain

2 Actively Recruiting

Not Applicable, Phase 2, Phase 3

Adrenergic Alpha-Antagonists

0 Actively Recruiting

Migraine

51 Actively Recruiting

Phase 4, Not Applicable, Phase 1, Phase 3, Phase 2, Early Phase 1

Hemangioma

0 Actively Recruiting

Gastroesophageal variceal hemorrhage prophylaxis

0 Actively Recruiting

Migraine Disorders

1 Actively Recruiting

Phase 3

Catecholamines

0 Actively Recruiting

Thyroid Crisis

0 Actively Recruiting

Hypertensive disease

27 Actively Recruiting

Not Applicable, Phase 1, Phase 2, Phase 3

Pheochromocytoma

0 Actively Recruiting

Thyrotoxicosis

0 Actively Recruiting

Cardiovascular Mortality

0 Actively Recruiting

Myocardial Infarction

0 Actively Recruiting

Tremor

0 Actively Recruiting

Cardiomyopathy, Hypertrophic

0 Actively Recruiting

Proliferating Infantile Hemangioma

0 Actively Recruiting

Psychomotor Agitation

0 Actively Recruiting

Propranolol Hydrochloride Reviews: What are patients saying about Propranolol Hydrochloride?

5

Patient Review

3/30/2021

Propranolol Hydrochloride for Anxious

I'm 61 and have been struggling with anxiety for the past year. This medication really helps to take the edge off within half an hour.

5

Patient Review

2/14/2020

Propranolol Hydrochloride for Anxious

This medication has been extremely helpful for me in managing my anxiety, bipolar disorder, and panic attacks. After being taken off of Xanax (which I had been taking for 20 years), the withdrawals were awful; but this medication has really helped to ease those symptoms and manage my overall mental health.

4.7

Patient Review

11/15/2019

Propranolol Hydrochloride for Migraine Prevention

I've only just started taking this medication, but it seems to be going well so far. I'm still experiencing some pain, but that could just be because it's the first day.

4.3

Patient Review

3/12/2022

Propranolol Hydrochloride for Anxious

This treatment was very effective at reducing my anxiety in the moment, but it did make me feel quite relaxed and slow. I wouldn't recommend it for long-term use, but it was excellent and very safe.

4

Patient Review

11/13/2019

Propranolol Hydrochloride for High Blood Pressure

So far, I'm really pleased with this medication. It's helped lower my blood pressure and anxiety levels; however, I am feeling pretty tired most of the time. I'm hoping that side-effect will go away soon.

3.7

Patient Review

1/11/2021

Propranolol Hydrochloride for Migraine Prevention

I've been using this for a few months now and it's helped, but the side effects are really tough to deal with. I get dizzy spells, back pain, nausea, and chest pains with coughing fits. I'm hoping my doctor will let me stop taking it soon.

3.7

Patient Review

3/21/2022

Propranolol Hydrochloride for Essential Tremor

I've had this tremor since birth, and it's always been quite bad. The medication does help to some extent, but I think it might be time for an increase in dosage.

3.7

Patient Review

6/10/2018

Propranolol Hydrochloride for Essential Tremor

I've been on this mix of drugs for 30 years and it's helped a lot. I just think that, after all this time, there should be an alternative to upping the dosage every 10 years or so.

3

Patient Review

9/5/2021

Propranolol Hydrochloride for Essential Tremor

I've been taking the 45 mg dose once per day for a week now. I have experienced some nausea and dizziness, but nothing too severe. I'm wondering if these side effects will go away with time? If so, approximately how long will it take?

2.3

Patient Review

8/26/2020

Propranolol Hydrochloride for Anxious

Unfortunately, this medication caused more problems than it solved. I experienced regular, severe stomach pains that made it difficult to even walk around. Do not recommend if you're looking for help with anxiety or rapid heart rates.

2.3

Patient Review

1/15/2019

Propranolol Hydrochloride for Paroxysmal Supraventricular Tachycardia

I have supraventricular tachycardia and unfortunately, this medicine has done nothing to reduce my palpitations. I started with a 2.5 mg dose, then 5 mg, then 10 mg, and now I'm up to 20 mg. Sadly, there has been no change.

2

Patient Review

1/13/2022

Propranolol Hydrochloride for Anxious

I'm on the first night of taking this drug and I haven't been able to sleep at all. I've also experienced dry mouth, dizziness, and anxiety.

1.7

Patient Review

11/16/2017

Propranolol Hydrochloride for High Blood Pressure

I took this drug because I had issues with Lisinopril and an allergy to Amlodipine. Started using it 3 weeks after the allergy to Amlodipine. Only used for 6 days. Didn't see much difference in BP. Experienced nerve pain and a lump in my throat. Also got a red rash all over my body. Took myself off of the medication due to extreme dizziness.

1.7

Patient Review

12/21/2021

Propranolol Hydrochloride for Migraine Prevention

This was honestly one of the worst experiences of my life. I couldn't breathe at all.

1

Patient Review

12/11/2018

Propranolol Hydrochloride for Migraine Prevention

I had a really severe reaction to this medication- my mouth and hands were swollen and itchy. I stopped taking the medication and saw a huge improvement.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about propranolol hydrochloride

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Should I take propranolol in the morning or at night?

"This medicine should be taken at bedtime. You can take it with or without food."

Answered by AI

How fast does propranolol hydrochloride work?

"It can take up to an hour for the physical effects of propranolol to be noticeable. If you have been prescribed propranolol for performance anxiety, your healthcare provider may suggest that you take the medication at a specific time before an event."

Answered by AI

What are side effects of propranolol?

"You may feel dizzy, lightheaded, or tired as your body adjusts to the medication. You may also have nausea or vomiting, stomach pain, vision changes, trouble sleeping, and unusual dreams. If you have any of these side effects, call your doctor or pharmacist."

Answered by AI

Does propranolol hydrochloride help anxiety?

"Propranolol is sometimes used to help with anxiety that is unrelated to its approved uses. This includes anxiety related to physical performance, such as dry mouth, nausea, fast pulse, or shaky hands. Propranolol is approved by the FDA to treat many other conditions, such as high blood pressure and tremors."

Answered by AI

Clinical Trials for Propranolol Hydrochloride

Image of Miles Square Health Center Chicago in Chicago, United States.

Food is Medicine for High Blood Pressure and Obesity

Any Age
All Sexes
Chicago, IL

The goal of this clinical trial is to treat both hypertension and obesity in adults using a food is medicine framework. Participants will be randomized 1:1 to FIM+DASH or usual-care control. The 24-week trial includes a 12-week FIM+DASH intervention followed by a 12-week maintenance period and leverages existing partnerships with community-based organizations for home food delivery and culinary skill-skill building. The main questions it aims to answer are: (1) What is the effect of FIM+DASH vs. usual care control on blood pressure? (2) What is the effect of FIM+DASH vs. usual care control on DASH diet adherence (diet quality), body weight, and waist circumference? (3) How to identify factors associated with the sustainability and scalability of FIM+DASH in real-world settings?

Phase 2
Waitlist Available

Miles Square Health Center Chicago (+3 Sites)

Image of Northwestern University in Chicago, United States.

Exercise Program for Atrial Fibrillation and Heart Failure

60 - 99
All Sexes
Chicago, IL

Atrial fibrillation (AF) and heart failure with preserved ejection fraction (HFpEF) are very common conditions that often occur together and result in worsening symptoms and reduced quality of life (QoL). Limitations being able to participate in activities of daily living is a primary complaint for AF-HFpEF patients, yet effective strategies to address this issue remain limited. While exercise interventions targeting aerobic training (AT) are recommended for patients with AF and HFpEF, unique challenges exist in this patient population who tend to be older. Specifically, many older patients with AF and HFpEF have muscle weakness, sarcopenia and frailty, that can make aerobic-focused exercise difficult and less tolerable. This study proposes that starting with progressive resistance training (PRT) before aerobic exercise may overcome these issues by improving muscle strength, making AT more manageable, and leading to better health outcomes. The goal of this study is to assess whether a sequential exercise program, named 'PREACTIVE' improves how people feel, decrease the amount of symptoms, and their ability to participate in exercise and activities. This study will specifically test a sequenced exercise approach of resistance training followed by aerobic exercise to improve symptoms, and quality of life in AF-HFpEF.

Waitlist Available
Has No Placebo

Northwestern University

Deepika Laddu, PhD

Image of Fort Bend ISD in Sugar Land, United States.

Wellbeing Interventions for Anxiety

10 - 20
All Sexes
Sugar Land, TX

The goal of this clinical trial is to learn if psychology and music based interventions can impact anxiety and overall wellbeing in adolescents enrolled in choral music classes. The main questions it aims to answer are: Do specific psychology and music based breathing interventions impact anxiety and overall wellbeing in adolescents? Do specific psychology and music based performance anxiety reduction interventions impact anxiety and overall wellbeing in adolescents? Do specific psychology and music based emotion regulation interventions impact anxiety and overall wellbeing in adolescents? Researchers will compare results of pre-test data, post-test data, qualitative interviews, and surveys of adult choral directors to see if there is a measurable impact on adolescent anxiety and overall wellbeing. Participants will: * Use box breathing during choral music warm-ups to connect choral breathing to breathing for anxiety reduction * Use "magnify" technique to compare cognitive distortions regarding an upcoming performance that may cause anxiety to the most likely realistic outcome * Use emotion regulation through song lyrics technique to connect lyrics of choral music repertoire to participants experienced emotions

Waitlist Available
Has No Placebo

Fort Bend ISD

Jane Kuehne, PhD

Have you considered Propranolol Hydrochloride clinical trials?

We made a collection of clinical trials featuring Propranolol Hydrochloride, we think they might fit your search criteria.
Go to Trials
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Heparin Dosing for Blood Clots and Heart Conditions

18+
All Sexes
Alexandria, VA

The goal of this clinical trial study is to test whether a mathematical calculation, using the patient's gender, weight and kidney function, can better predict a patient's heparin goal dose than a flat number of units per patient weight can. Participants will have the first dose of heparin infusion calculated, after which if adjustments are needed, the Hospital's prebuilt table for results driven dosing for this purpose is used. The researchers will compare the time it takes for the participants to get to the desired goal using the patient's information for calculation versus patients in the past who received the medication using the flat rate. The hypothesis is that the patients with enhanced personal data, gender, weight and kidney function, included for the initial dose, will get to their goal lab value sooner and with less chance of delay or overshooting the goal. A quicker time to goal lab value is beneficial to patients in many ways, including earlier treatment of the clot or coronary issue that the patient is experiencing.

Phase 4
Waitlist Available

Inova Alexandria Hospital

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Cuffless PPG Monitor for High Blood Pressure

18+
All Sexes
Miami, FL

This study aims to validate the accuracy and reliability of blood pressure (BP) estimates obtained over 24 hours using a PPG-based chest-patch device compared to the gold standard ambulatory blood pressure monitoring (ABPM) method using an upper arm cuff-based oscillometric BP device, in both hypertensive and normotensive individuals referred by their provider to undergo a 24-hours ABPM for clinical indication. The Awake/Asleep test, which is the primary test recommended for automated wearable cuffless BP devices that are cuff-calibrated (based on the 2023 European Society of Hypertension (ESH) recommendations for the validation of cuffless blood pressure measuring devices), will be conducted in this study. The secondary aim of the study is to assess the feasibility and convenience of the PPG-based device.

Waitlist Available
Has No Placebo

U Health (+1 Sites)

Ziad Zoghby, M.D., M.B.A.

Biobeat Technologies Ltd.

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Embolization for Migraine

18 - 80
All Sexes
Baltimore, MD

This study is to test the safety and feasibility of a procedure called embolization of the middle meningeal arteries (MMA), using a product called Onyx. Embolization creates a plug in the arteries. MMA embolization with Onyx is not approved for use in patients with migraines, but is currently used in patients with subdural hematomas. The FDA is allowing the use of Onyx in this study. It is thought that by using Onyx to block the middle meningeal arteries, the amount of migraine-causing substances which are released into the brain's bloodstream will be reduced. The company that manufactures Onyx, Medtronic, is providing the supplies for this study. Participants will be in the study for about 8 months after enrolling, including 6 months of follow up after the procedure. The participants will be asked to complete a daily headache diary and continue the participant's regular migraine medications. Participants will also have several clinic visits and be asked to provide blood samples for research.

Waitlist Available
Has No Placebo

Johns Hopkins Medicine

Risheng Xu, MD, PhD

Medtronic

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