Hp 129Xenon for Bronchiolitis Obliterans

Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Bronchiolitis ObliteransHp 129Xenon - Drug
Any Age
All Sexes
What conditions do you have?

Study Summary

This trial is testing new methods of imaging transplanted lungs to see if they can detect changes early on that could lead to BOS, a chronic allograft rejection.

Eligible Conditions
  • Bronchiolitis Obliterans

Treatment Effectiveness

Study Objectives

0 Primary · 1 Secondary · Reporting Duration: 12 months post transplant

12 months post transplant
Capture 129Xe and proton MRI Images for clinician assessment

Trial Safety

Awards & Highlights

No Placebo Group
All patients enrolled in this trial will receive the new treatment.

Trial Design

1 Treatment Group

Hp 129Xenon
1 of 1

Experimental Treatment

45 Total Participants · 1 Treatment Group

Primary Treatment: Hp 129Xenon · No Placebo Group · Phase 1 & 2

Hp 129Xenon
Experimental Group · 1 Intervention: Hp 129Xenon · Intervention Types: Drug

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 12 months post transplant

Who is running the clinical trial?

Children's Hospital Medical Center, CincinnatiLead Sponsor
771 Previous Clinical Trials
5,424,235 Total Patients Enrolled
3 Trials studying Bronchiolitis Obliterans
2,046 Patients Enrolled for Bronchiolitis Obliterans
Jason Woods, PhDPrincipal InvestigatorChildren's Hospital Medical Center, Cincinnati
6 Previous Clinical Trials
320 Total Patients Enrolled

Eligibility Criteria

Age Any Age · All Participants · 2 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You need to be able to stop breathing for a short time, up to 16 seconds.
You had a lung transplant within the past 10 years or you are currently being evaluated for a possible lung transplant.

Frequently Asked Questions

Are there opportunities for enrolment in this research effort?

"Affirmative, the information found on clinicaltrials.gov implies that this experiment is actively recruiting participants. It was initially posted on September 9th 2020 and has been modified as recently as December 17th 2020. 45 individuals are needed to contribute at a single site." - Anonymous Online Contributor

Unverified Answer

How many participants are currently being analyzed as part of this research endeavor?

"Affirmative. Clinicaltrials.gov data indicate that this clinical trial is presently attempting to recruit participants, which was first posted on September 9th 2020 and last edited December 17th 2020. 45 patients are required for the study at a single site." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.