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What is Prevpac
ClarithromycinThe Generic name of this drug
Treatment SummaryLansoprazole, sold under the brand name Prevacid, is a medication that reduces the production of stomach acid. It works by targeting the gastric H,K-ATPase pumps and is commonly used to treat ulcerative diseases, gastroesophageal reflux disease (GERD), and other conditions caused by too much stomach acid.
Biaxinis the brand name
Prevpac Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Biaxin
Clarithromycin
1991
187
Approved as Treatment by the FDA
Clarithromycin, also known as Biaxin, is approved by the FDA for 12 uses which include Community Acquired Pneumonia (CAP) and Otitis Media (OM) .Community Acquired Pneumonia (CAP)
Otitis Media (OM)
Urinary Tract Infection (UTI)
Mycobacterial Infections
Bacterial Infections
Acute maxillary sinusitis
Mycobacterium Infections
HIV
Duodenal Ulcer
Used to treat Duodenal ulcer caused by helicobacter pylori in combination with Amoxicillin
Streptococcal Pharyngitis
Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB)
Tonsillitis
Effectiveness
How Prevpac Affects PatientsLansoprazole works by blocking the enzyme that helps produce stomach acid. It is effective throughout the day and night, and is used to treat ulcers, reduce pain related to ulcers, and relieve heartburn symptoms. It can also be used to lower the amount of acid produced in people with conditions like Zollinger-Ellison Syndrome.
How Prevpac works in the bodyLansoprazole is a type of drug called a proton pump inhibitor (PPI). It needs to be activated in an acidic environment. Once activated, it binds to two proteins in the stomach called Cys813 and Cys321, which helps reduce the amount of acid in the stomach. This binding is strong and long-lasting, giving it a long-term effect on reducing acid levels.
When to interrupt dosage
The prescribed dosage of Prevpac is contingent upon the determined condition, such as A History of Gastric or Duodenal Ulcers, Stomach Ulcer and Erosive Esophagitis. The dosage quantity deviates according to the delivery technique described in the table below.Condition
Dosage
Administration
HIV
, 500.0 mg, 250.0 mg, 250.0 mg/mL, 125.0 mg/mL, 1000.0 mg
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Kit, Tablet - Oral, Tablet, Tablet, coated, Tablet, coated - Oral, For suspension, For suspension - Oral, Granule, for suspension, Granule, for suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Kit - Oral
Urinary Tract Infection (UTI)
, 500.0 mg, 250.0 mg, 250.0 mg/mL, 125.0 mg/mL, 1000.0 mg
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Kit, Tablet - Oral, Tablet, Tablet, coated, Tablet, coated - Oral, For suspension, For suspension - Oral, Granule, for suspension, Granule, for suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Kit - Oral
Community Acquired Pneumonia (CAP)
, 500.0 mg, 250.0 mg, 250.0 mg/mL, 125.0 mg/mL, 1000.0 mg
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Kit, Tablet - Oral, Tablet, Tablet, coated, Tablet, coated - Oral, For suspension, For suspension - Oral, Granule, for suspension, Granule, for suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Kit - Oral
Bacterial Infections
, 500.0 mg, 250.0 mg, 250.0 mg/mL, 125.0 mg/mL, 1000.0 mg
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Kit, Tablet - Oral, Tablet, Tablet, coated, Tablet, coated - Oral, For suspension, For suspension - Oral, Granule, for suspension, Granule, for suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Kit - Oral
Lyme Disease
, 500.0 mg, 250.0 mg, 250.0 mg/mL, 125.0 mg/mL, 1000.0 mg
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Kit, Tablet - Oral, Tablet, Tablet, coated, Tablet, coated - Oral, For suspension, For suspension - Oral, Granule, for suspension, Granule, for suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Kit - Oral
Streptococcal Pharyngitis
, 500.0 mg, 250.0 mg, 250.0 mg/mL, 125.0 mg/mL, 1000.0 mg
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Kit, Tablet - Oral, Tablet, Tablet, coated, Tablet, coated - Oral, For suspension, For suspension - Oral, Granule, for suspension, Granule, for suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Kit - Oral
Otitis Media (OM)
, 500.0 mg, 250.0 mg, 250.0 mg/mL, 125.0 mg/mL, 1000.0 mg
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Kit, Tablet - Oral, Tablet, Tablet, coated, Tablet, coated - Oral, For suspension, For suspension - Oral, Granule, for suspension, Granule, for suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Kit - Oral
Bartonellosis
, 500.0 mg, 250.0 mg, 250.0 mg/mL, 125.0 mg/mL, 1000.0 mg
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Kit, Tablet - Oral, Tablet, Tablet, coated, Tablet, coated - Oral, For suspension, For suspension - Oral, Granule, for suspension, Granule, for suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Kit - Oral
Acute maxillary sinusitis
, 500.0 mg, 250.0 mg, 250.0 mg/mL, 125.0 mg/mL, 1000.0 mg
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Kit, Tablet - Oral, Tablet, Tablet, coated, Tablet, coated - Oral, For suspension, For suspension - Oral, Granule, for suspension, Granule, for suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Kit - Oral
Pertussis
, 500.0 mg, 250.0 mg, 250.0 mg/mL, 125.0 mg/mL, 1000.0 mg
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Kit, Tablet - Oral, Tablet, Tablet, coated, Tablet, coated - Oral, For suspension, For suspension - Oral, Granule, for suspension, Granule, for suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Kit - Oral
Tonsillitis
, 500.0 mg, 250.0 mg, 250.0 mg/mL, 125.0 mg/mL, 1000.0 mg
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Kit, Tablet - Oral, Tablet, Tablet, coated, Tablet, coated - Oral, For suspension, For suspension - Oral, Granule, for suspension, Granule, for suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Kit - Oral
Mycobacterium Infections
, 500.0 mg, 250.0 mg, 250.0 mg/mL, 125.0 mg/mL, 1000.0 mg
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Kit, Tablet - Oral, Tablet, Tablet, coated, Tablet, coated - Oral, For suspension, For suspension - Oral, Granule, for suspension, Granule, for suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Kit - Oral
Bacterial Endocarditis
, 500.0 mg, 250.0 mg, 250.0 mg/mL, 125.0 mg/mL, 1000.0 mg
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Kit, Tablet - Oral, Tablet, Tablet, coated, Tablet, coated - Oral, For suspension, For suspension - Oral, Granule, for suspension, Granule, for suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Kit - Oral
Duodenal Ulcer
, 500.0 mg, 250.0 mg, 250.0 mg/mL, 125.0 mg/mL, 1000.0 mg
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Kit, Tablet - Oral, Tablet, Tablet, coated, Tablet, coated - Oral, For suspension, For suspension - Oral, Granule, for suspension, Granule, for suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Kit - Oral
Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB)
, 500.0 mg, 250.0 mg, 250.0 mg/mL, 125.0 mg/mL, 1000.0 mg
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Kit, Tablet - Oral, Tablet, Tablet, coated, Tablet, coated - Oral, For suspension, For suspension - Oral, Granule, for suspension, Granule, for suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Kit - Oral
Bacterial Endocarditis
, 500.0 mg, 250.0 mg, 250.0 mg/mL, 125.0 mg/mL, 1000.0 mg
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Kit, Tablet - Oral, Tablet, Tablet, coated, Tablet, coated - Oral, For suspension, For suspension - Oral, Granule, for suspension, Granule, for suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Kit - Oral
Mycobacterial Infections
, 500.0 mg, 250.0 mg, 250.0 mg/mL, 125.0 mg/mL, 1000.0 mg
, Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated - Oral, Tablet, film coated, Kit, Tablet - Oral, Tablet, Tablet, coated, Tablet, coated - Oral, For suspension, For suspension - Oral, Granule, for suspension, Granule, for suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Kit - Oral
Warnings
Prevpac ContraindicationsCondition
Risk Level
Notes
Liver Dysfunction
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
cholestatic jaundice
Do Not Combine
Common Prevpac Drug Interactions
Drug Name
Risk Level
Description
(R)-warfarin
Major
The metabolism of (R)-warfarin can be decreased when combined with Clarithromycin.
(S)-Warfarin
Major
The metabolism of (S)-Warfarin can be decreased when combined with Clarithromycin.
1,2-Benzodiazepine
Major
The metabolism of 1,2-Benzodiazepine can be decreased when combined with Clarithromycin.
3,5-diiodothyropropionic acid
Major
The metabolism of 3,5-diiodothyropropionic acid can be decreased when combined with Clarithromycin.
5-androstenedione
Major
The metabolism of 5-androstenedione can be decreased when combined with Clarithromycin.
Prevpac Toxicity & Overdose RiskLansoprazole is usually well-tolerated with few side effects, such as abdominal pain, constipation, diarrhea, and nausea. Very rarely, it can cause a serious skin reaction known as toxic epidermal necrolysis. Taking 600 mg of lansoprazole does not appear to cause any adverse effects or symptoms of overdose. Lansoprazole is classified as Pregnancy Category B in the US, meaning it is likely safe to use during pregnancy. However, there is not enough research available to know if lansoprazole is safe to use while breastfeeding.
Prevpac Novel Uses: Which Conditions Have a Clinical Trial Featuring Prevpac?
Four active clinical trials are underway to assess the utility of Prevpac in ameliorating Stomach Ulcers, NSAID-induced Gastric Ulcers and a History of Gastric or Duodenal Ulcers.Condition
Clinical Trials
Trial Phases
HIV
146 Actively Recruiting
Phase 2, Not Applicable, Phase 1, Phase 3, Phase 4, Early Phase 1
Pertussis
1 Actively Recruiting
Phase 1
Tonsillitis
0 Actively Recruiting
Bacterial Endocarditis
2 Actively Recruiting
Not Applicable
Bartonellosis
0 Actively Recruiting
Bacterial Endocarditis
0 Actively Recruiting
Urinary Tract Infection (UTI)
24 Actively Recruiting
Phase 2, Phase 1, Phase 4, Phase 3, Not Applicable
Otitis Media (OM)
0 Actively Recruiting
Acute maxillary sinusitis
0 Actively Recruiting
Bacterial Infections
0 Actively Recruiting
Duodenal Ulcer
0 Actively Recruiting
Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB)
0 Actively Recruiting
Streptococcal Pharyngitis
1 Actively Recruiting
Not Applicable
Community Acquired Pneumonia (CAP)
1 Actively Recruiting
Not Applicable
Lyme Disease
7 Actively Recruiting
Phase 3, Phase 2, Phase 1
Mycobacterium Infections
0 Actively Recruiting
Mycobacterial Infections
0 Actively Recruiting
Prevpac Reviews: What are patients saying about Prevpac?
5Patient Review
6/12/2013 I've been on this medication for six days now and have had zero negative side effects other than an increased appetite. This product has really improved my life.
4.3Patient Review
12/8/2013 This treatment is very effective, but can be quite expensive. My doctor suggested that I buy the three medicines separately, which ended up being much cheaper in the long run.
3.3Patient Review
2/20/2014 While the Prepac is quite expensive, it only cost me $120 out of pocket. I did experience some side effects like a bad taste in my mouth and headaches, but nothing too severe.
2.7Patient Review
4/3/2015 I felt nauseated for the first two days after starting this medication, but that went away. However, now I have diarrhea every time I eat while on this med. Additionally, my heart rate is high at night and I've been feeling more anxious. Not sure if the benefits outweigh the costs here.
2.3Patient Review
5/29/2013 I developed a painful burning sensation on my tongue over the course of five days.
1.7Patient Review
7/26/2014 I'm on day two of the treatment and, like other reviewers have said, the metallic taste in my mouth is nauseating. I feel tired and it's hard to sleep at night. I don't understand the side effects.I have taken 4 500mg of amoxicillin prior to going to the dentist and have taken clarithromycin for an infection after a root canal, with no problems. Will start eating pribiotic yogart to see if it stems nausia.I hope this is worth it.
1Patient Review
5/4/2016 I would approach this treatment with caution. I had some really unpleasant side effects that made me feel terrible. If you decide to go ahead with it, be prepared for the possibility of feeling very sick.
Patient Q&A Section about prevpac
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What does Prevpac cost?
"The average cost for a 112-day supply of Prevpac oral kit (500 mg-500 mg-30 mg) is around $1,018, depending on the pharmacy you visit. Prices given are for cash paying customers only and may not be valid with insurance plans."
Answered by AI
What drugs are in a Prevpac?
"The PREVPAC pack contains enough medicine for 30 days. It is made up of two PREVACID 30-mg capsules, four amoxicillin 500-mg capsules, USP, and two clarithromycin 500-mg tablets, USP."
Answered by AI
Is Prevpac an antibiotic?
"The Prevpac medication is a combination of a proton pump inhibitor, a penicillin antibiotic, and a macrolide antibiotic. It is used to prevent stomach ulcers that are caused by infection with Helicobacter pylori bacteria."
Answered by AI
What is Prevpac used to treat?
"This product contains 2 medicines: clarithromycin and amoxicillin.
This product is used to treat stomach/intestinal ulcers caused by the bacteria H. pylori and to prevent the ulcers from returning. Treating an ulcer reduces the risk of serious damage to the lining of the stomach/intestines (such as bleeding, tearing, blockage). This product contains 2 medicines: clarithromycin and amoxicillin. Clarithromycin is in a class of drugs called macrolide antibiotics. Amoxicillin is in a class of drugs called penicillin-like antibiotics."
Answered by AI