Transcranial Magnetic Stimulation for Meth Addiction
What You Need to Know Before You Apply
What is the purpose of this trial?
The purpose of this study is to learn more about how accelerated theta burst stimulation affects methamphetamine craving and brain activity. Theta burst stimulation is a unique transcranial magnetic stimulation (TMS) paradigm that is efficient and potent.
Do I need to stop my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications.
Is transcranial magnetic stimulation (TMS) safe for humans?
Research shows that transcranial magnetic stimulation (TMS), including theta burst stimulation (TBS), is generally safe for humans. Some participants experienced mild side effects like headaches, and one person had a temporary neurological event, but overall, it was well-tolerated in studies involving people with methamphetamine and cocaine use disorders.12345
How does the treatment Theta Burst Stimulation differ from other treatments for meth addiction?
Theta Burst Stimulation (TBS) is a unique form of transcranial magnetic stimulation that uses rapid bursts of magnetic pulses to target specific brain areas, potentially reducing cravings and improving cognitive function in methamphetamine users. Unlike traditional treatments, TBS is non-invasive and can be administered in shorter sessions, which may improve patient compliance.12345
What data supports the effectiveness of the treatment Theta Burst Stimulation for meth addiction?
Research suggests that Theta Burst Stimulation (TBS) can reduce drug cravings in methamphetamine users, similar to its effects in reducing cravings for cocaine and nicotine. Studies have shown that TBS is as effective as other forms of brain stimulation, like repetitive transcranial magnetic stimulation (rTMS), in reducing cravings and drug use.12567
Who Is on the Research Team?
Gopalkumar Rakesh, MD
Principal Investigator
University of Kentucky
Are You a Good Fit for This Trial?
This trial is for English-speaking adults aged 18-65 with HIV who crave methamphetamine and have a history of Meth Use Disorder. It's not for those with seizure disorders, schizophrenia, brain injuries, intracranial metal, past bad reactions to TMS, or inconsistent task performance.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive TMS sessions, including iTBS and cTBS, over 4 days with two sessions daily
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Theta Burst Stimulation
Find a Clinic Near You
Who Is Running the Clinical Trial?
Gopalkumar Rakesh
Lead Sponsor