Prevacid 24 Hr

Zollinger-Ellison Syndrome, Curling Ulcer, maintenance of healing Erosive esophagitis + 9 more

Treatment

5 FDA approvals

5 Active Studies for Prevacid 24 Hr

What is Prevacid 24 Hr

Lansoprazole

The Generic name of this drug

Treatment Summary

Lansoprazole is a medication that prevents the production of stomach acid. It is sold under the brand name Prevacid and is a type of proton pump inhibitor (PPI). Lansoprazole can help to heal ulcers and other diseases caused by too much acid in the stomach. It is used to treat gastroesophageal reflux disease (GERD) and other conditions.

Prevacid

is the brand name

image of different drug pills on a surface

Prevacid 24 Hr Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Prevacid

Lansoprazole

1995

326

Approved as Treatment by the FDA

Lansoprazole, otherwise known as Prevacid, is approved by the FDA for 5 uses like Duodenal Ulcer and Zollinger-Ellison Syndrome .

Duodenal Ulcer

Used to treat Duodenal Ulcer in combination with Amoxicillin

Zollinger-Ellison Syndrome

Helps manage Zollinger-Ellison Syndrome

hypersecretory conditions

Helps manage hypersecretory conditions

Helicobacter Pylori Infection

Used to treat Helicobacter Pylori Infection in combination with Amoxicillin

Curling Ulcer

Used to treat Duodenal Ulcer in combination with Amoxicillin

Effectiveness

How Prevacid 24 Hr Affects Patients

Lansoprazole works by blocking an enzyme (H+,K+-ATPase), which is the last step in the process of the stomach producing acid. This drug can be taken at any time of the day and works to reduce both daytime and nighttime acid production. It is effective in healing duodenal ulcers, relieving pain related to ulcers, and reducing symptoms of heartburn. Additionally, it can reduce the amount of pepsin produced, making it useful in treating conditions with high acid production, like Zollinger-Ellison Syndrome.

How Prevacid 24 Hr works in the body

Lansoprazole is a type of drug known as a Proton Pump Inhibitor (PPI). It only works when it is exposed to an acidic environment, which causes it to react with certain molecules on the surface of cells. This reaction forms a bond that prevents acid from being secreted. This bond is strong, so lansoprazole can provide long-term inhibition of acid secretion.

When to interrupt dosage

The advised dose of Prevacid 24 Hr depends upon the recognized condition, including A History of Gastric or Duodenal Ulcers, Stomach Ulcer and Erosive Esophagitis. The measure of dosage is contingent upon the method of delivery described in the accompanying table.

Condition

Dosage

Administration

Zollinger-Ellison Syndrome

, 15.0 mg, 30.0 mg, 30.0 mg/mL

Kit, , Oral, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Capsule, delayed release pellets - Oral, Capsule, delayed release pellets, Tablet, delayed release - Oral, Tablet, delayed release, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intravenous, Injection, Injection - Intravenous, Suspension, Suspension - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Capsule - Oral, Capsule, Kit - Oral

Curling Ulcer

, 15.0 mg, 30.0 mg, 30.0 mg/mL

Kit, , Oral, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Capsule, delayed release pellets - Oral, Capsule, delayed release pellets, Tablet, delayed release - Oral, Tablet, delayed release, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intravenous, Injection, Injection - Intravenous, Suspension, Suspension - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Capsule - Oral, Capsule, Kit - Oral

maintenance of healing Erosive esophagitis

, 15.0 mg, 30.0 mg, 30.0 mg/mL

Kit, , Oral, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Capsule, delayed release pellets - Oral, Capsule, delayed release pellets, Tablet, delayed release - Oral, Tablet, delayed release, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intravenous, Injection, Injection - Intravenous, Suspension, Suspension - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Capsule - Oral, Capsule, Kit - Oral

Duodenal Ulcer

, 15.0 mg, 30.0 mg, 30.0 mg/mL

Kit, , Oral, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Capsule, delayed release pellets - Oral, Capsule, delayed release pellets, Tablet, delayed release - Oral, Tablet, delayed release, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intravenous, Injection, Injection - Intravenous, Suspension, Suspension - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Capsule - Oral, Capsule, Kit - Oral

NSAID use

, 15.0 mg, 30.0 mg, 30.0 mg/mL

Kit, , Oral, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Capsule, delayed release pellets - Oral, Capsule, delayed release pellets, Tablet, delayed release - Oral, Tablet, delayed release, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intravenous, Injection, Injection - Intravenous, Suspension, Suspension - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Capsule - Oral, Capsule, Kit - Oral

hypersecretory conditions

, 15.0 mg, 30.0 mg, 30.0 mg/mL

Kit, , Oral, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Capsule, delayed release pellets - Oral, Capsule, delayed release pellets, Tablet, delayed release - Oral, Tablet, delayed release, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intravenous, Injection, Injection - Intravenous, Suspension, Suspension - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Capsule - Oral, Capsule, Kit - Oral

Helicobacter Pylori Infection

, 15.0 mg, 30.0 mg, 30.0 mg/mL

Kit, , Oral, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Capsule, delayed release pellets - Oral, Capsule, delayed release pellets, Tablet, delayed release - Oral, Tablet, delayed release, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intravenous, Injection, Injection - Intravenous, Suspension, Suspension - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Capsule - Oral, Capsule, Kit - Oral

Erosive Esophagitis

, 15.0 mg, 30.0 mg, 30.0 mg/mL

Kit, , Oral, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Capsule, delayed release pellets - Oral, Capsule, delayed release pellets, Tablet, delayed release - Oral, Tablet, delayed release, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intravenous, Injection, Injection - Intravenous, Suspension, Suspension - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Capsule - Oral, Capsule, Kit - Oral

Ulcer Healing

, 15.0 mg, 30.0 mg, 30.0 mg/mL

Kit, , Oral, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Capsule, delayed release pellets - Oral, Capsule, delayed release pellets, Tablet, delayed release - Oral, Tablet, delayed release, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intravenous, Injection, Injection - Intravenous, Suspension, Suspension - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Capsule - Oral, Capsule, Kit - Oral

A History of Gastric or Duodenal Ulcers

, 15.0 mg, 30.0 mg, 30.0 mg/mL

Kit, , Oral, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Capsule, delayed release pellets - Oral, Capsule, delayed release pellets, Tablet, delayed release - Oral, Tablet, delayed release, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intravenous, Injection, Injection - Intravenous, Suspension, Suspension - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Capsule - Oral, Capsule, Kit - Oral

Stomach Ulcer

, 15.0 mg, 30.0 mg, 30.0 mg/mL

Kit, , Oral, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Capsule, delayed release pellets - Oral, Capsule, delayed release pellets, Tablet, delayed release - Oral, Tablet, delayed release, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intravenous, Injection, Injection - Intravenous, Suspension, Suspension - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Capsule - Oral, Capsule, Kit - Oral

Gastroesophageal reflux disease

, 15.0 mg, 30.0 mg, 30.0 mg/mL

Kit, , Oral, Capsule, delayed release - Oral, Capsule, delayed release, Tablet, orally disintegrating, delayed release, Tablet, orally disintegrating, delayed release - Oral, Capsule, delayed release pellets - Oral, Capsule, delayed release pellets, Tablet, delayed release - Oral, Tablet, delayed release, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Intravenous, Injection, Injection - Intravenous, Suspension, Suspension - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Capsule - Oral, Capsule, Kit - Oral

Warnings

There are 20 known major drug interactions with Prevacid 24 Hr.

Common Prevacid 24 Hr Drug Interactions

Drug Name

Risk Level

Description

Albendazole

Major

The metabolism of Albendazole can be decreased when combined with Lansoprazole.

Amoxapine

Major

The metabolism of Amoxapine can be decreased when combined with Lansoprazole.

Apixaban

Major

The metabolism of Apixaban can be decreased when combined with Lansoprazole.

Artemether

Major

The metabolism of Artemether can be decreased when combined with Lansoprazole.

Astemizole

Major

The metabolism of Astemizole can be decreased when combined with Lansoprazole.

Prevacid 24 Hr Toxicity & Overdose Risk

Lansoprazole is usually well-tolerated, with occasional side effects like abdominal pain, constipation, diarrhea, and nausea. In rare cases, lansoprazole may cause a serious skin condition known as toxic epidermal necrolysis. Taking up to 600mg of lansoprazole has been reported to have no adverse effects. While lansoprazole is categorized as safe for pregnant women, it is unknown if it is excreted in breast milk. It is generally considered safe to use while breastfeeding.

image of a doctor in a lab doing drug, clinical research

Prevacid 24 Hr Novel Uses: Which Conditions Have a Clinical Trial Featuring Prevacid 24 Hr?

Four active trials are presently assessing the potential of Prevacid 24 Hr in addressing Stomach Ulcers, NSAID-induced Gastric Ulcers and a Past of Gastric or Duodenal Ulcers.

Condition

Clinical Trials

Trial Phases

hypersecretory conditions

0 Actively Recruiting

A History of Gastric or Duodenal Ulcers

0 Actively Recruiting

Duodenal Ulcer

0 Actively Recruiting

maintenance of healing Erosive esophagitis

0 Actively Recruiting

Curling Ulcer

0 Actively Recruiting

NSAID use

0 Actively Recruiting

Ulcer Healing

1 Actively Recruiting

Not Applicable

Stomach Ulcer

0 Actively Recruiting

Helicobacter Pylori Infection

2 Actively Recruiting

Not Applicable, Phase 4

Zollinger-Ellison Syndrome

0 Actively Recruiting

Gastroesophageal reflux disease

0 Actively Recruiting

Erosive Esophagitis

2 Actively Recruiting

Phase 2, Phase 3

Prevacid 24 Hr Reviews: What are patients saying about Prevacid 24 Hr?

5

Patient Review

8/5/2010

Prevacid 24 Hr for Condition in which Stomach Acid is Pushed Into the Esophagus

I had been taking the generic version of Prilosec for 3 years, but it stopped being effective. I tried taking two pills a day, which helped some, but not all the time. Then I switched to Prevacid and it worked wonderfully--until my prescription coverage said they would no longer pay for it. Thankfully, my doctor was able to get prior approval so that I could keep taking it.

5

Patient Review

1/2/2012

Prevacid 24 Hr for Excessive Production of Stomach Acid

This medication does a great job of preventing acid reflux and Acid Aspiration Syndrome. However, the trade-off is that I experience a lot of gas. It's not your typical 'silent but deadly' gas either; this is the kind that will clear a room. Not ideal, but it's worth it to be able to sleep without fear of aspirating stomach acid.

5

Patient Review

7/23/2011

Prevacid 24 Hr for Condition in which Stomach Acid is Pushed Into the Esophagus

I've been taking this medication for over a month to relieve stomach discomfort. Unfortunately, it comes with the side effect of anal irritation, itching and swelling. I used to take pantoprazole (prescription), but my HMO upped the copay so much that I had to switch.

5

Patient Review

6/4/2010

Prevacid 24 Hr for Condition in which Stomach Acid is Pushed Into the Esophagus

Prilosec had been treating my acid reflux for years, but it suddenly stopped working in February. I tried taking two pills a day, but that didn't help at all. My pharmacist recommended Prevacid, and after ten days of taking it, I finally feel relief.

5

Patient Review

10/1/2010

Prevacid 24 Hr for Inflammation of the Esophagus with Erosion

I had good results with this treatment and didn't experience any negative side effects.

5

Patient Review

6/25/2010

Prevacid 24 Hr for Conditions of Excess Stomach Acid Secretion

This treatment is only moderately effective.

5

Patient Review

2/15/2018

Prevacid 24 Hr for Medication Treatment for Healing Ulcer of the Duodenum

I'm really thankful for this treatment and how it's helped me.

5

Patient Review

4/30/2010

Prevacid 24 Hr for Excessive Production of Stomach Acid

5

Patient Review

5/29/2013

Prevacid 24 Hr for Stomach Ulcer

This treatment really helped me. I'm grateful for modern medicine.

4.7

Patient Review

4/27/2010

Prevacid 24 Hr for Condition in which Stomach Acid is Pushed Into the Esophagus

4.3

Patient Review

11/10/2011

Prevacid 24 Hr for Condition in which Stomach Acid is Pushed Into the Esophagus

I had really bad GERD and tried a bunch of different drugs that didn't help much. But then I found Prevacid. It's been great! I take 30 mg every morning and haven't had any problems since. The generic works just as well as the brand name, so definitely try it if you're suffering from GERD.

4

Patient Review

6/17/2010

Prevacid 24 Hr for Condition in which Stomach Acid is Pushed Into the Esophagus

Prevacid has helped with the severe pain from acid reflux when omeprazole didn't. I can eat foods that trigger acid reflux occasionally when taking Prevacid.

3.7

Patient Review

4/10/2012

Prevacid 24 Hr for Conditions of Excess Stomach Acid Secretion

I switched to Prevacid from Aciphex because I kept getting urinary tract infections, and it's helped with that issue. However, now my scalp is constantly itchy, which is very irritating. Has anyone else had this problem? Additionally, I have a slight shortness of breath, but it was worse when taking Aciphex.

3.7

Patient Review

3/22/2011

Prevacid 24 Hr for Conditions of Excess Stomach Acid Secretion

I've tried a lot of different treatments for my GERD, and this is by far the best one. No more stomach pain or diarrhea!

3.7

Patient Review

8/24/2012

Prevacid 24 Hr for Medication Treatment for Healing Erosive Esophagitis

I just had an EGD done and was using Prevacid for over a year.

3.3

Patient Review

5/9/2010

Prevacid 24 Hr for Condition in which Stomach Acid is Pushed Into the Esophagus

2.3

Patient Review

1/28/2013

Prevacid 24 Hr for Conditions of Excess Stomach Acid Secretion

I was recommended by the RX to use this product and it has not helped me except to waste my money.

2

Patient Review

2/22/2012

Prevacid 24 Hr for Stomach Ulcer from Aspirin or Ibuprofen-Like Drugs

I unfortunately have not found relief from this treatment, even after taking it for almost two weeks now. I'm actually getting worse. Gaviscon is next on my list to try, as it has good reviews and was recommended by my sister.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about prevacid 24 hr

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Prevacid 24 HR over the counter?

"Prevacid®24HR is an over-the-counter medication that provides relief from frequent heartburn for up to 24 hours. It contains the active ingredient, lansoprazole, and works by reducing the amount of acid in your stomach."

Answered by AI

How long can I take Prevacid 24HR?

"Studies have found that Prevacid 24HR (a 15 mg dose) often works as well as the prescription Prevacid. People can take one Prevacid 24HR pill daily for 14 days, but users should not take the drug for more than 14 days."

Answered by AI

Can you take Prevacid 24 hour twice a day?

"It is recommended that you take one Prevacid®24HR pill before eating in the morning, every day for 14 days. You should not take more than one pill in a 24-hour period."

Answered by AI

Does Prevacid work immediately?

"People often report feeling relief from heartburn symptoms within one day of taking lansoprazole, but it can take up to four days for the drug to reach its full effect."

Answered by AI

Clinical Trials for Prevacid 24 Hr

Image of Brigham and Women's Hospital in Boston, United States.

Argon Plasma for Helicobacter Pylori Infection

18+
All Sexes
Boston, MA

The objective of the study is to investigate the efficacy and safety of an argon plasma-based therapy - HEAPE - in treating H. pylori infections during endoscopic procedures. By filling the stomach with sodium chloride solution that is treated with APC (PAL), the Investigators hypothesize a significant reduction in H. pylori. The use of PAL instead of direct application of APC allows for a broader and more homogeneous application throughout the stomach and a faster procedure time, as the fluid bypasses the thermal effects typically associated with higher electrical power settings and focuses on the bactericidal action of PAL. It is a procedure that does not involve thermal ablation of the stomach lining. Thus, side effects should be expected to be as low as possible. Two different PAL generation modalities will be compared in this study: 1. HEAPE direct: This modality is the direct generation of PAL in the stomach. The stomach is filled with sodium chloride solution which is then treated with APC. With HEAPE direct a potential decrease of reactive species is avoided, as the treatment happens directly at the intended location in the H. pylori infected stomach. 2. Pre-HEAPE: This modality features the treatment of sodium chloride with APC outside of the patient in a sterile container. After the APC treatment, the generated PAL is administered into the stomach with a syringe through the working channel of the endoscope. Pre-HEAPE allows an easier handling of the APC probe as the treatment of the sodium chloride solution can be done without an endoscope. To evaluate the immediate effect of this novel treatment approach the metabolic activity of H. pylori will be assessed using a urea breath test (UBT) before and after treatment. A reduction in H. pylori levels can be detected by a reduction in urease activity in the breath test. After the HEAPE procedure, patients are treated with antibiotics (best practice) as they would be under normal circumstances. Four weeks after treatment, another UBT is performed to determine if H. pylori has been eradicated or if additional antibiotic treatment is indicated. This two-arm, randomized, pilot, single-center, prospective clinical study is designed to evaluate the safety, tolerability and proof of concept that PAL has the ability to eradicate or reduce the bacterial load of H. pylori in humans.

Recruiting
Has No Placebo

Brigham and Women's Hospital

Christopher C Thompson, MD

Erbe Elektromedizin GmbH

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