Treatment for Menopause

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Mayo Clinic in Rochester, Rochester, MNMenopause+2 More
Eligibility
40 - 60
Female
What conditions do you have?
Select

Study Summary

This trial looks at how hot flashes affect women's risk for cardiovascular disease.

Eligible Conditions
  • Menopause
  • Hot Flashes
  • Vasomotor Instability

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

2 Primary · 0 Secondary · Reporting Duration: Continuous measurement of vascular conductance during infusion of each drug- 3min at baseline and at each drug dose (~60min total of continuous forearm vascular conductance measurements)

Continuous measurement of muscle sympathetic nerve activity at rest and in response to stressors (~75min of continuous data collection once a sympathetic nerve signal is found)
Compare sympathetic function in women with low and high frequency hot flashes
Continuous measurement of vascular conductance during infusion of each drug- 3min at baseline and at each drug dose (~60min total of continuous forearm vascular conductance measurements)
Compare microvascular function in women with low and high frequency hot flashes

Trial Safety

Safety Progress

1 of 3

Trial Design

0 Treatment Group

120 Total Participants · 0 Treatment Group

Primary Treatment: Treatment · No Placebo Group · N/A

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: continuous measurement of vascular conductance during infusion of each drug- 3min at baseline and at each drug dose (~60min total of continuous forearm vascular conductance measurements)

Who is running the clinical trial?

Mayo ClinicLead Sponsor
2,952 Previous Clinical Trials
3,447,665 Total Patients Enrolled
2 Trials studying Menopause
768 Patients Enrolled for Menopause
National Institutes of Health (NIH)NIH
2,471 Previous Clinical Trials
24,591,593 Total Patients Enrolled
3 Trials studying Menopause
251 Patients Enrolled for Menopause
National Heart, Lung, and Blood Institute (NHLBI)NIH
3,616 Previous Clinical Trials
47,118,176 Total Patients Enrolled
12 Trials studying Menopause
122,955 Patients Enrolled for Menopause
Michael Joyner, MDPrincipal InvestigatorMayo Clinic
2 Previous Clinical Trials

Eligibility Criteria

Age 40 - 60 · Female Participants · 5 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You do not smoke.
You are not overweight.
You are a female with at least one ovary.
You do not have any heart or blood vessel problems.

Frequently Asked Questions

Are elderly participants sought after in this research endeavor?

"This research project is only open to patients between the ages of 45-55. However, there are 8 trials for minors and 55 studies available for those over 65 years old." - Anonymous Online Contributor

Unverified Answer

To what extent is this clinical trial being populated by participants?

"Affirmative. Information on clinicaltrials.gov seems to indicate that this medical experiment is currently enrolling patients; the trial was first posted on February 24th 2022 and most recently edited on March 14th 2022. The research team requires 120 individuals from 1 site for their study." - Anonymous Online Contributor

Unverified Answer

Are there any still vacancies in this clinical investigation?

"As per clinicaltrials.gov, this ongoing research is actively recruiting participants from the time of its initial posting on February 24th 2022 to its latest revision on March 14th 2022." - Anonymous Online Contributor

Unverified Answer

Could I be considered a candidate for the clinical experiment?

"This clinical trial is enrolling 120 adults aged 45-55 experiencing hot flashes. To qualify, applicants must have at least one ovary and cannot be smokers, obese or taking any drugs that might affect cardiovascular function. In addition, they need to be free from any existing cardiovascular conditions" - Anonymous Online Contributor

Unverified Answer

Have there been previous experiments involving this particular therapeutic approach?

"Presently, 29 investigations of this particular treatment are underway. 5 of these ongoing clinical trials have advanced to Phase 3. The primary research centres for most of the studies can be found in Salt Lake City, Utah though there remain 50 locations running relevant experiments." - Anonymous Online Contributor

Unverified Answer

What is the usual indication for this therapeutic regimen?

"This therapeutic approach is effective at managing hypotension, preventing preterm labour, and alleviating the symptoms of chronic obstructive airway disease." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.