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What is Platinol
CisplatinThe Generic name of this drug
Treatment SummaryCisplatin (also known as cisplatinum or CDDP) is a chemotherapy drug used to treat a variety of cancers, including lung cancer, ovarian cancer, sarcomas, lymphomas, and germ cell tumors. It was the first drug in its class and was followed by other similar drugs, such as carboplatin and oxaliplatin.
Cisplatinis the brand name
Platinol Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Cisplatin
Cisplatin
2000
28
Effectiveness
How Platinol Affects PatientsCisplatin is a type of medicine used to treat cancer. It works by attacking the DNA in cells and stopping them from dividing and replicating. Cisplatin adds extra molecules to the DNA which stops it from being used correctly and causes it to be coded incorrectly, leading to cell death. It is not specific to any part of the cell cycle and works in three different ways to achieve the same result.
How Platinol works in the bodyAlkylating agents fight cancer by blocking DNA and RNA production. They do this by attaching alkyl groups to DNA bases, causing them to fragment and preventing synthesis. They also form bonds between atoms in the DNA which stop it from being separated and used. Lastly, they make it so the nucleotides don't match properly, which causes mutations in the DNA.
When to interrupt dosage
The measure of Platinol is contingent upon the diagnosed affliction, including Refractory to Standard Therapies, Advanced Ovarian Cancer and Neoplasm Metastasis. The amount of dosage also differs according to the technique of delivery (e.g. Injection, solution or Solution) specified in the table below.Condition
Dosage
Administration
Advanced Ovarian Cancer
1.0 mg/mL, , 5.0 mg/mL, 0.5 mg/mL
, Intravenous, Injection, Injection - Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intravenous, Solution, Liquid, Liquid - Intravenous
Neoplasm Metastasis
1.0 mg/mL, , 5.0 mg/mL, 0.5 mg/mL
, Intravenous, Injection, Injection - Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intravenous, Solution, Liquid, Liquid - Intravenous
advanced Testicular cancer
1.0 mg/mL, , 5.0 mg/mL, 0.5 mg/mL
, Intravenous, Injection, Injection - Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intravenous, Solution, Liquid, Liquid - Intravenous
Refractory to Standard Therapies
1.0 mg/mL, , 5.0 mg/mL, 0.5 mg/mL
, Intravenous, Injection, Injection - Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intravenous, Solution, Liquid, Liquid - Intravenous
Neoplasm Metastasis
1.0 mg/mL, , 5.0 mg/mL, 0.5 mg/mL
, Intravenous, Injection, Injection - Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intravenous, Solution, Liquid, Liquid - Intravenous
Advance Directives
1.0 mg/mL, , 5.0 mg/mL, 0.5 mg/mL
, Intravenous, Injection, Injection - Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Solution - Intravenous, Solution, Liquid, Liquid - Intravenous
Warnings
Platinol has three contraindications and should be avoided when contending with any of the conditions mentioned in the subsequent table.Platinol ContraindicationsCondition
Risk Level
Notes
Bone Marrow
Do Not Combine
Pulse Frequency
Do Not Combine
hearing loss or impairment
Do Not Combine
Common Platinol Drug Interactions
Drug Name
Risk Level
Description
2-Methoxyethanol
Major
The risk or severity of adverse effects can be increased when Cisplatin is combined with 2-Methoxyethanol.
9-(N-methyl-L-isoleucine)-cyclosporin A
Major
The risk or severity of adverse effects can be increased when Cisplatin is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Abatacept
Major
The risk or severity of adverse effects can be increased when Cisplatin is combined with Abatacept.
Abetimus
Major
The risk or severity of adverse effects can be increased when Cisplatin is combined with Abetimus.
Acteoside
Major
The risk or severity of adverse effects can be increased when Cisplatin is combined with Acteoside.
Platinol Novel Uses: Which Conditions Have a Clinical Trial Featuring Platinol?
Thirteen active studies are currently evaluating the use of Platinol in the treatment of Advanced Ovarian Cancer, Neoplasm Metastasis and Secondary Neoplasms.Condition
Clinical Trials
Trial Phases
Advance Directives
0 Actively Recruiting
advanced Testicular cancer
0 Actively Recruiting
Neoplasm Metastasis
1 Actively Recruiting
Phase 2
Refractory to Standard Therapies
0 Actively Recruiting
Advanced Ovarian Cancer
14 Actively Recruiting
Phase 3, Early Phase 1, Phase 2, Phase 1, Not Applicable
Neoplasm Metastasis
0 Actively Recruiting
Platinol Reviews: What are patients saying about Platinol?
3Patient Review
12/3/2008Patient Q&A Section about platinol
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is Platinol used for?
"Platinol is a prescription medicine that is used to help relieve the symptoms for Metastatic Testicular Tumors, Advanced Bladder cancer, and Metastatic Ovarian Carcinoma. Platinol can be used by itself or with other medications depending on the situation."
Answered by AI
Is cisplatin a strong chemo drug?
"Cisplatin is a powerful chemotherapy drug used to treat ovarian cancer, even though resistance is typical. In ovarian germ cell cancer, cisplatin use leads to high response rates."
Answered by AI
What is the generic name for Platinol?
"The trade name drugs Platinol® and Platinol®-AQ are both generic names for the drug cisplatin. In some cases, health care professionals may use other names for the drug when referring to the generic drug name cisplatin."
Answered by AI
Is Platinol a chemo drug?
"Cisplatin, which is marketed under the brand name Platinol®, is a type of chemotherapy drug that can be used to treat patients with various types of cancer, including mesothelioma. This form of treatment can be used alone or in conjunction with other mesothelioma treatments and medications."
Answered by AI