Stress Reduction Therapies for Ovarian Cancer
Trial Summary
Will I have to stop taking my current medications?
The trial requires that you do not take any β-blockers or COX inhibitors, as chronic treatment with these medications is an exclusion criterion. If you are currently on these medications, you would need to stop taking them to participate in the trial.
What data supports the effectiveness of the treatment for stress reduction in ovarian cancer patients?
Is music therapy safe for humans?
Music therapy is generally considered safe and can be beneficial for various physical, emotional, and psychological needs. It is used as an adjunct therapy in many medical settings and has been shown to help with stress, anxiety, and other symptoms without replacing traditional medical treatments.46789
How does music therapy differ from other treatments for ovarian cancer?
Music therapy is unique because it uses music to help reduce stress, anxiety, and improve mood, which can be particularly beneficial for cancer patients. Unlike traditional medical treatments, it involves active or passive participation in music sessions led by a trained therapist, focusing on emotional and psychological support rather than directly targeting the cancer itself.1351011
What is the purpose of this trial?
This trial tests if propranolol, etodolac, MBRT, and music therapy can reduce stress in patients having major surgeries. These treatments aim to lower anxiety, pain, and promote relaxation. Propranolol has been found to reduce anxiety in various medical settings, including day case surgery.
Research Team
Kara Long Roche, MD
Principal Investigator
Memorial Sloan Kettering Cancer Center
Eligibility Criteria
This trial is for adults over 18 with advanced ovarian, fallopian tube, or peritoneal carcinoma who are scheduled for surgery. Participants must understand the study and consent to it. Exclusions include active infections, pregnancy, chronic autoimmune diseases, other clinical trial participation that conflicts with this one, and certain medical conditions like asthma or liver failure.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Preoperative Intervention
Participants receive mind-body resilience training/MBRT, music therapy, propranolol, and etodolac before surgery
Surgical Procedure
Participants undergo primary debulking surgery (PDS) or interval debulking surgery (IDS)
Postoperative Intervention
Participants receive postoperative mind-body resilience training/MBRT, music therapy, propranolol, and etodolac
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Etodolac
- Mind-body Resilience Training
- Music Therapy
- Propranolol
Find a Clinic Near You
Who Is Running the Clinical Trial?
Memorial Sloan Kettering Cancer Center
Lead Sponsor