CT vs PET Scans for Coronary Artery Disease
Trial Summary
What is the purpose of this trial?
The overall goal of this project is to compare the absolute quantification of myocardial perfusion done by using CT myocardial perfusion imaging (CT-MPI) and the coronary flow measured by using CT Fractional Flow Reserve analysis (CT-FFR) to the gold standard represented by PET myocardial perfusion imaging (PET-MPI).
Research Team
Carlo De Cecco, MD, PhD
Principal Investigator
Emory University
Eligibility Criteria
This trial is for individuals who need a CT scan to check for coronary artery disease and are willing to follow the study's procedures. They must not be pregnant, nursing, or have taken certain diabetes medications recently. People with implanted heart devices, severe allergies to contrast material used in scans, kidney issues, low blood pressure, or specific heart rhythm problems cannot participate.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Imaging and Analysis
Participants undergo PET-MPI, CT-MPI, and CT-FFR imaging for analysis of myocardial perfusion and coronary flow
Follow-up
Participants are monitored for safety and effectiveness after imaging procedures
Treatment Details
Interventions
- CT-FFR
- CT-MPI
- PET-MPI Protocol
- Regadenoson
Find a Clinic Near You
Who Is Running the Clinical Trial?
Emory University
Lead Sponsor
Siemens Medical Solutions
Industry Sponsor