Peridex

Mucositis, Chronic Pain, Eczema + 89 more

Treatment

3 FDA approvals

20 Active Studies for Peridex

What is Peridex

Chlorhexidine

The Generic name of this drug

Treatment Summary

Chlorhexidine is an antimicrobial drug used to kill germs on the skin and in the mouth. It is composed of two 4-chlorophenyl rings, two biguanide groups, and a hexamethylene chain. Chlorhexidine is effective against a wide range of bacteria, yeasts, and viruses. It was first developed in the UK in the 1950s and made available in the US in the 1970s.

Hibiclens

is the brand name

image of different drug pills on a surface

Peridex Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Hibiclens

Chlorhexidine

1976

229

Approved as Treatment by the FDA

Chlorhexidine, also called Hibiclens, is approved by the FDA for 3 uses such as Dental Cavity and High Risk .

Dental Cavity

Used to treat Dental Cavity in combination with Sodium fluoride

High Risk

Used to treat High Risk in combination with Sodium fluoride

Dental Caries

Used to treat Dental Cavity in combination with Sodium fluoride

Effectiveness

How Peridex Affects Patients

Chlorhexidine is an antibiotic that fights bacteria and viruses. Its effectiveness depends on the amount taken - at lower doses, it will prevent bacteria from growing, and at higher doses, it will kill bacteria. Chlorhexidine is also able to stick to surfaces like dentine, preventing bacteria from colonizing it. However, if taken for long periods of time, it may cause staining of teeth and other oral surfaces. Allergic reactions to chlorhexidine may also occur, including anaphylaxis.

How Peridex works in the body

Chlorhexidine kills bacteria by interfering with their cell membranes. Chlorhexidine is positively charged and reacts with the negatively charged phosphate groups on the cells of bacteria. This reaction destroys the integrity of the cell, letting out its contents, and allows the chlorhexidine to enter the cell and cause it to die. The strength of the chlorhexidine determines whether it is bacteriostatic (slows down bacteria growth) or bactericidal (kills bacteria).

When to interrupt dosage

The measure of Peridex is contingent upon the determined disorder, including Wound, Oral Hygiene and Ringworm. The amount additionally shifts as per the technique of delivery (e.g. Rinse or Cream; Kit; Ointment; Solution) mentioned in the table beneath.

Condition

Dosage

Administration

Difficulty Swallowing

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Ringworm

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Tonsillitis

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Topical Antisepsis

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Minor Surgical Procedures

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Disinfection

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Antisepsis

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Dental Plaque

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Antisepsis

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Glossitis

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Sore Throat

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Gum Disease

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Eye

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Leg Ulcer

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Obstetrics

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Wound

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Cystoscopy

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Catheterization

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Pressure Ulcer

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Pharmacotherapy

, 20.0 mg/mL, 40.0 mg/mL, 0.04 mg/mL, 1.2 mg/mL, 31.5 mg/mL, 0.12 mg/mL, 0.1 mg/mL, 0.1 mg/mg, 10.0 mg/mL, 0.007075 mg/mg, 0.045 mg/mg, 2.5 mg, 0.02 mg/mg, 1.2 [iU]/mL, 500.0 mg, 0.0002 mg/mg, 213.0 mg/mL, 0.024 mg/mg, 0.048 mg/mg, 0.0075 mg/mL, 0.001 mg/mg, 145.6 mg/mL, 0.0236 mL/mL, 4.0 %, 0.5 %, 2.0 %, 10.0 %, 20.0 %, 0.05 %, 0.12 %, 1.0 %, 2.25 %, 0.02 mg/mL, 525.0 mg/mL, 1.5 %, 0.01 mg/mg, 0.015 %, 8.3 mg/mL, 0.005 mg/mg, 0.1 %, 200.0 mg/mL, 2.0 mg/mL, 1.0 mg/mL, 0.0283 mg/mg, 0.005448 mg/mg, 0.021508 mg/mg, 0.003 mg/mg, 0.025 mg/mL, 50.0 mg/mL, 0.0055 mg/mg, 0.5 mg/mL, 5.0 mg/mL, 0.011 mg/mg, 0.01 mg/mL, 4.5 mg/mL, 0.005 mg/mL, 35.0 mg/mL, 0.0045 mg/mL, 2.5 mg/mL, 1.0 mg, 0.00127 mg/mg, 0.1 mg, 7.5 mg, 0.002 mg/mg, 0.0035 units/units, 0.001 units/units, 0.0009 mg/mg, 4.0 mg/mL

, Topical, Liquid, Liquid - Topical, Solution, Solution - Topical, Rinse, Buccal, Rinse - Buccal, Sponge, Sponge - Topical, Oral, Rinse - Oral, Cloth - Topical, Cloth, Lotion, Lotion - Topical, Periodontal, Insert, extended release, Insert, extended release - Periodontal, Liquid - Buccal, Kit, Swab, Swab - Topical, Soap, Soap - Topical, Dental, Liquid - Dental, Rinse - Dental, Ophthalmic, Irrigation, Concentrate, Concentrate - Irrigation, Liquid - Ophthalmic, Gel, Gel - Topical, Kit; Solution, Kit; Solution - Dental, Liquid; Mouthwash, Liquid - Oral, Mouthwash - Buccal, Mouthwash, Spray - Topical, Spray, Liquid; Mouthwash - Buccal, Ointment, Ointment - Topical, Liquid; Sponge, Liquid; Sponge - Topical, Dressing, Dressing - Topical, Cream, Cream - Topical, Solution - Buccal, Liquid; Mouthwash - Oral, Solution - Ophthalmic, Shampoo, Shampoo - Topical, Aerosol, Aerosol - Topical, Solution; Sponge, Solution; Sponge - Topical, Kit - Topical, Gel - Urethral, Urethral, Liquid - Extracorporeal, Extracorporeal, Gel - Extracorporeal, Solution - Oral, Kit - Oral, Kit - Buccal, Solution - Dental

Warnings

Peridex has one consensus contraindication, so it ought not to be used for the conditions indicated in the following table.

Peridex Contraindications

Condition

Risk Level

Notes

Severe Hypersensitivity Reactions

Do Not Combine

Chlorhexidine may interact with Pulse Frequency

There are 1 known major drug interactions with Peridex.

Common Peridex Drug Interactions

Drug Name

Risk Level

Description

Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen

Major

The therapeutic efficacy of Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen can be decreased when used in combination with Chlorhexidine.

Peridex Toxicity & Overdose Risk

The toxic dose of chlorhexidine in mice is greater than 5g/kg. If a small child ingests a small amount (1-2 ounces) of chlorhexidine, they may experience nausea, vomiting, and intoxication. Medical attention should be sought if the child has ingested more than 4 ounces or if intoxication symptoms appear. Treatment should involve providing supportive care.

Peridex Novel Uses: Which Conditions Have a Clinical Trial Featuring Peridex?

35 active studies are presently assessing the efficacy of Peridex in Disinfection, Breast Milk Production and Tissue Injury.

Condition

Clinical Trials

Trial Phases

Eczema

0 Actively Recruiting

Chronic Pain

124 Actively Recruiting

Not Applicable, Phase 2, Phase 4, Phase 3, Early Phase 1, Phase 1

Antisepsis

0 Actively Recruiting

Stomach Diseases

0 Actively Recruiting

recurrent Oral fungal infection

0 Actively Recruiting

Topical Antisepsis

0 Actively Recruiting

Dental Scaling

0 Actively Recruiting

Dental Caries

0 Actively Recruiting

Neurodermatitis

0 Actively Recruiting

Cystoscopy

0 Actively Recruiting

Injury Throat

0 Actively Recruiting

Hoarseness

0 Actively Recruiting

Minor Surgical Procedures

0 Actively Recruiting

Disinfection

0 Actively Recruiting

Mucositis

1 Actively Recruiting

Not Applicable

oral infections

1 Actively Recruiting

Not Applicable

Endoscopy

0 Actively Recruiting

High Risk

0 Actively Recruiting

Post-chemotherapy

0 Actively Recruiting

oral lesions

0 Actively Recruiting

Peridex Reviews: What are patients saying about Peridex?

5

Patient Review

6/22/2013

Peridex for Inflammation of the Gums

I've used Peridex since I lost five teeth to bone loss and gum disease. It's kept my gums healthy and I haven't had any problems since. If only I had known about this product sooner, I could have saved my teeth!

5

Patient Review

2/4/2012

Peridex for Inflammation of the Gums

I unfortunately had to stop using this product after only two tries. My tongue swelled and burned painfully, my face turned bright red, and I got hives all over my body. Be sure to read the precautions before use!

5

Patient Review

2/4/2016

Peridex for Inflammation of the Gums

I saw a significant reduction in inflammation after only two days of use. I don't know why there isn't more awareness about this drug; it could really help a lot of people. That said, I worry about the potential side effects.

5

Patient Review

9/12/2009

Peridex for Inflammation of the Gums

This has been a gamechanger since I can't brush my teeth. It's also helped with the swelling and tastes pretty good too.

5

Patient Review

3/16/2016

Peridex for Inflammation of the Gums

After just two days of using this rinse as directed by my dentist, I've seen a significant reduction in gum inflammation and bleeding. Can't wait to see how long it takes for the bleeding to stop altogether! This drug is great--it leaves your mouth feeling very clean.

4.7

Patient Review

8/30/2013

Peridex for Mouth Infection Prevention

After my crown lengthening procedure, my dentist gave me a bottle of this to use. I had been using Listerine and ACT mouthwashes regularly before the procedure, so I don't know how effective this was in preventing infection. However, my gum healed satisfactorily within a week's time.

4.7

Patient Review

11/7/2007

Peridex for Inflammation of the Gums

4

Patient Review

5/13/2013

Peridex for Sore Mouth due to Dentures or Poor Oral Hygiene

I had a dead tooth removed and was using this product as instructed twice daily. After finishing one bottle, I noticed my teeth were very stained by the gums. This has never happened before and I'm concerned about potential damage to my teeth.

3.7

Patient Review

11/25/2016

Peridex for Mouth Infection Prevention

After having five teeth extracted, my periodontist recommended this product to keep my mouth clean while it healed. However, after just one use I experienced burning on my tongue and itchiness around my face - worse than the discomfort of the extraction sites. I used it a second time, not making the connection, and had the same reaction. Needless to say, I will not be using this product again.

3.7

Patient Review

12/2/2012

Peridex for Mouth Infection Prevention

I had used this treatment before and knew it would be effective for my dental situation. I ended up having to get a tooth extracted, but the implant went smoothly thanks in part to this product.

3.3

Patient Review

1/25/2011

Peridex for Inflammation of the Gums

The inflammation in my gums from the first temporary crown was incredibly painful, but this oral rinse alleviated the pain within two hours. I'm very grateful to the dentist for prescribing it.

2.7

Patient Review

8/4/2021

Peridex for Inflammation of the Gums

Browning of teeth, especially in the lower front.

2.3

Patient Review

2/23/2010

Peridex for Inflammation of the Gums

I unfortunately had a negative reaction to this medication. I suffer from SVTs, so I'm more sensitive to medications than most people. This one caused my heart to go out of rhythm and made me lightheaded, and these effects lasted for around four hours.

2.3

Patient Review

2/15/2009

Peridex for Inflammation of the Gums

This medication definitely works to clean my gums, but the aftertaste is incredibly bitter. I understand why they say not to drink anything afterwards, because everything tastes terrible anyway.

2

Patient Review

8/31/2020

Peridex for Inflammation of the Gums

Despite reading and following all instructions, after 3 doses, I found my tongue had turned brown, my teeth had darkened, and my taste was way off. 3 days later, my gums are still irritated, I had a metallic taste in my mouth and my tongue and teeth are still dark.

1

Patient Review

3/25/2012

Peridex for Mouth Infection Prevention

I've been taking this medication for two days now and have developed a very sore throat, which is unfortunately a common side effect. I hope it goes away soon; other than that, my gums have been feeling better since starting the treatment.

Patient Q&A Section about peridex

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Will Peridex get rid of infection?

"If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

This medication will not help a viral or fungal infection such as canker sores or oral thrush. You may experience some side effects while taking this medication, such as staining of the teeth or tongue, changes in taste, mouth irritation, or mouth sores. If you experience any of these side effects, talk to your doctor or pharmacist."

Answered by AI

What is Peridex prescribed for?

"This medication is used in addition to regular brushing and flossing to treat gingivitis. Gingivitis is a gum disease that causes red, swollen, or easily bleeding gums. Chlorhexidine is a drug that belongs to a class of drugs called antimicrobials."

Answered by AI

Can I buy Peridex over the counter?

"Peridex is a mouthwash that is available both over the counter and by prescription. It is used to treat the symptoms of gingivitis and is often used in conjunction with other treatments such as scaling and root planing. Peridex belongs to a class of drugs known as oral antibiotics."

Answered by AI

Is Peridex the same as Listerine?

"Your dentist will prescribe you chlorhexidine (Peridex) as a prescription medication. Listerine is available over the counter, but it doesn't work in the same way as chlorhexidine."

Answered by AI

Clinical Trials for Peridex

Image of UC Davis Medical Center in Sacramento, United States.

Antibiotic Carriers for Breast Reconstruction

18+
Female
Sacramento, CA

Infections after tissue expander breast reconstruction can lead to pain, additional surgeries, and loss of the reconstruction. This study will compare two types of antibiotic carriers used during surgery to help lower the risk of infection. One carrier is a non-absorbable PMMA disc, and the other is an absorbable antibiotic bead. Both release antibiotics directly into the breast pocket after surgery. About 100 patients will be randomly assigned to receive one of these two carriers at the time of tissue expander placement. After surgery, small samples of fluid around the tissue expander will be collected during routine clinic visits. These samples will be tested to measure how much antibiotic is present over time. The study will also track infections, tissue expander loss, and other complications during the first 90 days after surgery. The goal is to learn how much antibiotic each carrier delivers and whether one method is more effective at preventing infection.

Waitlist Available
Has No Placebo

UC Davis Medical Center

Ara A Salibian, MD

Image of AltaSciences, Inc in Cypress, United States.

SBS-147 Safety Study

18 - 55
All Sexes
Cypress, CA

This study is part of the HEAL Initiative supported by the NIH. The purpose of this study is to learn how safe the study drug, SBS-147, is and how people's bodies respond to and process it. Researchers will also look for any side effects that may occur when taking SBS-147. Some participants will receive SBS-147, and others will receive a placebo, which looks the same but does not contain any medicine. This helps researchers fairly compare results. The study includes two parts: Single-Dose Group, where Participants receive SBS-147 or placebo one time. Multiple-Dose Group, where Participants receive SBS-147 or placebo once or twice daily for 7 days.

Phase 1
Waitlist Available

AltaSciences, Inc

Jeff Reich, MD

Sparian Biosciences, Inc

Have you considered Peridex clinical trials?

We made a collection of clinical trials featuring Peridex, we think they might fit your search criteria.
Go to Trials

Have you considered Peridex clinical trials?

We made a collection of clinical trials featuring Peridex, we think they might fit your search criteria.
Go to Trials
Image of University of Virginia in Charlottesville, United States.

Pharyngeal Wall Augmentation for Speech Disorder

18+
All Sexes
Charlottesville, VA

Some head and neck cancer survivors develop velopharyngeal dysfunction (VPD), a problem with closure between the soft palate and throat that can cause nasal-sounding speech, food or liquid leaking into the nose, difficulty swallowing, and reduced quality of life. This study aims to better understand VPD in this population and to evaluate whether pharyngeal wall augmentation (plumping up the back wall of the throat) can improve speech and swallowing. Participants will undergo a multidisciplinary assessment including physical examination, flexible nasolaryngoscopy, speech recording and acoustic analysis, nasometry, clinical swallowing evaluation, and fiberoptic endoscopic evaluation of swallowing (FEES). Aim 1: Determine the prevalence, severity, and functional impact of VPD in head and neck cancer survivors. Aim 2: Assess the feasibility and usefulness of advanced diagnostic tools for VPD. The investigators hypothesize that high nasalance scores (\>1 SD above normal) will accurately predict VPD with at least 75% positive predictive value and will correlate with worse communication-related quality of life (CPIB). The investigators also hypothesize that participants with VPD will have more pharyngeal residue or nasal regurgitation on FEES, and that these findings will be associated with lower swallowing-related quality of life (SWAL-QOL). Aim 3: Evaluate the effectiveness of pharyngeal wall augmentation injections for improving speech intelligibility and swallowing function. The investigators expect that this treatment will lead to measurable changes in both objective assessments and patient-reported outcomes. The results will help improve diagnosis and management of VPD in head and neck cancer survivors.

Recruiting
Has No Placebo

University of Virginia

Vanessa Torrecillas, MD

Image of University of Toronto in Toronto, Canada.

SALI-10 Oral Probiotics for Gum Disease

18 - 70
All Sexes
Toronto, Canada

Gingivitis is among the most prevalent oral diseases worldwide, affecting an estimated 50-90% of adults. It is a reversible condition primarily caused by microbial plaque accumulation on teeth and gingival surfaces, which triggers inflammation. Standard care emphasizes plaque reduction through oral hygiene, and research shows gingivitis can be reversed once hygiene resumes. The classic experimental gingivitis (EG) model developed in 1965 by Löe and Silness demonstrated the direct link between plaque buildup and gingival inflammation, further confirming that gingival health can be restored after resuming proper care. Microbial ecology shifts are central to gingivitis pathogenesis. In health, the oral microbiome is dominated by gram-positive Streptococcus species. With plaque accumulation, microbial communities transition to gram-negative periopathogens such as Porphyromonas, Tannerella, Treponema, and Prevotella. This dysbiosis provokes heightened inflammation, tissue damage, and, in susceptible individuals, progression to periodontitis. Individual variability in the inflammatory response has been associated with differences in the presence and activity of beneficial streptococci. Certain strains of Streptococcus salivarius produce lantibiotics called salivaricins-polycyclic antimicrobial peptides containing lanthionine residues. Salivaricins inhibit oral pathogens and have been investigated for their antimicrobial and probiotic properties, particularly in the context of rising antibiotic resistance. Probiotic S. salivarius strains isolated from healthy individuals have demonstrated safety and antimicrobial potential in previous studies, supporting their use in preventing oral and respiratory infections. A strain of S. salivarius designated SALI-10 produces a lantibiotic, Salivaricin 10, and is being evaluated as a candidate for gingivitis prevention. This strain is hypothesized to (1) help stabilize populations of beneficial streptococci during plaque accumulation, (2) competitively inhibit periopathogens such as Porphyromonas and Prevotella, and (3) suppress the dysbiotic shift toward gram-negative dominance. By contributing to microbial balance and reducing inflammatory triggers, SALI-10 may support resilient host-microbe interactions associated with gingival health. This approach may offer a dual antimicrobial and microbiome-stabilizing strategy with relevance to gingivitis management and longer-term periodontal health.

Phase 2
Recruiting

University of Toronto

Dr. Michael Goldberg, MDM

Ostia Sciences

Have you considered Peridex clinical trials?

We made a collection of clinical trials featuring Peridex, we think they might fit your search criteria.
Go to Trials