What is Orapred Odt
Prednisolone phosphateThe Generic name of this drug
Treatment SummaryPrednisolone phosphate is a steroid medication used to treat inflammation, weaken the immune system, and stop the growth of tumors. It was approved by the FDA in 1973 and has a similar effect to cortisol.
Pediapredis the brand name
Orapred Odt Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Pediapred
Prednisolone phosphate
1986
71
Approved as Treatment by the FDA
Prednisolone phosphate, also called Pediapred, is approved by the FDA for 14 uses such as Gastroenteritis and Ophthalmia, Sympathetic .Gastroenteritis
Ophthalmia, Sympathetic
Swollen feet or ankles
Multiple Sclerosis
Respiratory Diseases
Endocrine Disorders
Disease
Allergic Conditions
Dermatological Disease
Collagen Diseases
Neoplastic Disease
Temporal Arteritis
Ocular Inflammation
Uveitis
Effectiveness
How Orapred Odt Affects PatientsPrednisolone is a type of drug called a corticosteroid, which helps to reduce inflammation in the body. It works by blocking signals that create inflammation, and takes effect quickly - usually within 2-4 hours. The amount of prednisolone required by patients can be much higher than what is naturally produced by the body. Taking prednisolone also increases the risk of suppressed hormones and infections, so it is important to be aware of these risks before use.
How Orapred Odt works in the bodyCorticosteroids, when taken in low doses, can reduce inflammation by narrowing the blood vessels and decreasing the movement of white blood cells. These effects are caused by changes in gene expression that occur when the corticosteroid binds to the glucocorticoid receptor. This binding also decreases the production of substances that cause inflammation, while increasing the production of substances that reduce inflammation. Taking corticosteroids in high doses over a long period of time can suppress the body's immune system and raise sodium levels while decreasing potassium levels.
When to interrupt dosage
The prescribed dosage of Orapred Odt is based upon the diagnosed disorder, including Uveitis, Ocular Inflammation and Ophthalmia, Sympathetic. The quantity of dosage changes according to the method of administration outlined in the table following.Condition
Dosage
Administration
Neoplastic Disease
30.0 mg, 10.0 mg/mL, 15.0 mg, 5.0 mg/mL, , 10.0 mg, 15.0 mg/mL, 1.25 mg/mL, 1.0 %, 0.125 %, 2.5 mg/mL, 2.3 mg/mL, 20.0 mg/mL, 25.0 mg/mL, 0.5 %
Solution / drops, , Solution / drops - Ophthalmic, Liquid - Ophthalmic, Solution - Ophthalmic, Tablet, orally disintegrating, Liquid, Solution, Oral, Liquid - Oral, Solution - Oral, Ophthalmic, Liquid; Solution / drops - Ophthalmic, Liquid; Solution / drops, Tablet, orally disintegrating - Oral
Multiple Sclerosis
30.0 mg, 10.0 mg/mL, 15.0 mg, 5.0 mg/mL, , 10.0 mg, 15.0 mg/mL, 1.25 mg/mL, 1.0 %, 0.125 %, 2.5 mg/mL, 2.3 mg/mL, 20.0 mg/mL, 25.0 mg/mL, 0.5 %
Solution / drops, , Solution / drops - Ophthalmic, Liquid - Ophthalmic, Solution - Ophthalmic, Tablet, orally disintegrating, Liquid, Solution, Oral, Liquid - Oral, Solution - Oral, Ophthalmic, Liquid; Solution / drops - Ophthalmic, Liquid; Solution / drops, Tablet, orally disintegrating - Oral
Urinary Tract Infection (UTI)
30.0 mg, 10.0 mg/mL, 15.0 mg, 5.0 mg/mL, , 10.0 mg, 15.0 mg/mL, 1.25 mg/mL, 1.0 %, 0.125 %, 2.5 mg/mL, 2.3 mg/mL, 20.0 mg/mL, 25.0 mg/mL, 0.5 %
Solution / drops, , Solution / drops - Ophthalmic, Liquid - Ophthalmic, Solution - Ophthalmic, Tablet, orally disintegrating, Liquid, Solution, Oral, Liquid - Oral, Solution - Oral, Ophthalmic, Liquid; Solution / drops - Ophthalmic, Liquid; Solution / drops, Tablet, orally disintegrating - Oral
Ophthalmia, Sympathetic
30.0 mg, 10.0 mg/mL, 15.0 mg, 5.0 mg/mL, , 10.0 mg, 15.0 mg/mL, 1.25 mg/mL, 1.0 %, 0.125 %, 2.5 mg/mL, 2.3 mg/mL, 20.0 mg/mL, 25.0 mg/mL, 0.5 %
Solution / drops, , Solution / drops - Ophthalmic, Liquid - Ophthalmic, Solution - Ophthalmic, Tablet, orally disintegrating, Liquid, Solution, Oral, Liquid - Oral, Solution - Oral, Ophthalmic, Liquid; Solution / drops - Ophthalmic, Liquid; Solution / drops, Tablet, orally disintegrating - Oral
Temporal Arteritis
30.0 mg, 10.0 mg/mL, 15.0 mg, 5.0 mg/mL, , 10.0 mg, 15.0 mg/mL, 1.25 mg/mL, 1.0 %, 0.125 %, 2.5 mg/mL, 2.3 mg/mL, 20.0 mg/mL, 25.0 mg/mL, 0.5 %
Solution / drops, , Solution / drops - Ophthalmic, Liquid - Ophthalmic, Solution - Ophthalmic, Tablet, orally disintegrating, Liquid, Solution, Oral, Liquid - Oral, Solution - Oral, Ophthalmic, Liquid; Solution / drops - Ophthalmic, Liquid; Solution / drops, Tablet, orally disintegrating - Oral
Respiratory Diseases
30.0 mg, 10.0 mg/mL, 15.0 mg, 5.0 mg/mL, , 10.0 mg, 15.0 mg/mL, 1.25 mg/mL, 1.0 %, 0.125 %, 2.5 mg/mL, 2.3 mg/mL, 20.0 mg/mL, 25.0 mg/mL, 0.5 %
Solution / drops, , Solution / drops - Ophthalmic, Liquid - Ophthalmic, Solution - Ophthalmic, Tablet, orally disintegrating, Liquid, Solution, Oral, Liquid - Oral, Solution - Oral, Ophthalmic, Liquid; Solution / drops - Ophthalmic, Liquid; Solution / drops, Tablet, orally disintegrating - Oral
Ocular Inflammation
30.0 mg, 10.0 mg/mL, 15.0 mg, 5.0 mg/mL, , 10.0 mg, 15.0 mg/mL, 1.25 mg/mL, 1.0 %, 0.125 %, 2.5 mg/mL, 2.3 mg/mL, 20.0 mg/mL, 25.0 mg/mL, 0.5 %
Solution / drops, , Solution / drops - Ophthalmic, Liquid - Ophthalmic, Solution - Ophthalmic, Tablet, orally disintegrating, Liquid, Solution, Oral, Liquid - Oral, Solution - Oral, Ophthalmic, Liquid; Solution / drops - Ophthalmic, Liquid; Solution / drops, Tablet, orally disintegrating - Oral
Collagen Diseases
30.0 mg, 10.0 mg/mL, 15.0 mg, 5.0 mg/mL, , 10.0 mg, 15.0 mg/mL, 1.25 mg/mL, 1.0 %, 0.125 %, 2.5 mg/mL, 2.3 mg/mL, 20.0 mg/mL, 25.0 mg/mL, 0.5 %
Solution / drops, , Solution / drops - Ophthalmic, Liquid - Ophthalmic, Solution - Ophthalmic, Tablet, orally disintegrating, Liquid, Solution, Oral, Liquid - Oral, Solution - Oral, Ophthalmic, Liquid; Solution / drops - Ophthalmic, Liquid; Solution / drops, Tablet, orally disintegrating - Oral
Gastroenteritis
30.0 mg, 10.0 mg/mL, 15.0 mg, 5.0 mg/mL, , 10.0 mg, 15.0 mg/mL, 1.25 mg/mL, 1.0 %, 0.125 %, 2.5 mg/mL, 2.3 mg/mL, 20.0 mg/mL, 25.0 mg/mL, 0.5 %
Solution / drops, , Solution / drops - Ophthalmic, Liquid - Ophthalmic, Solution - Ophthalmic, Tablet, orally disintegrating, Liquid, Solution, Oral, Liquid - Oral, Solution - Oral, Ophthalmic, Liquid; Solution / drops - Ophthalmic, Liquid; Solution / drops, Tablet, orally disintegrating - Oral
Swollen feet or ankles
30.0 mg, 10.0 mg/mL, 15.0 mg, 5.0 mg/mL, , 10.0 mg, 15.0 mg/mL, 1.25 mg/mL, 1.0 %, 0.125 %, 2.5 mg/mL, 2.3 mg/mL, 20.0 mg/mL, 25.0 mg/mL, 0.5 %
Solution / drops, , Solution / drops - Ophthalmic, Liquid - Ophthalmic, Solution - Ophthalmic, Tablet, orally disintegrating, Liquid, Solution, Oral, Liquid - Oral, Solution - Oral, Ophthalmic, Liquid; Solution / drops - Ophthalmic, Liquid; Solution / drops, Tablet, orally disintegrating - Oral
Uveitis
30.0 mg, 10.0 mg/mL, 15.0 mg, 5.0 mg/mL, , 10.0 mg, 15.0 mg/mL, 1.25 mg/mL, 1.0 %, 0.125 %, 2.5 mg/mL, 2.3 mg/mL, 20.0 mg/mL, 25.0 mg/mL, 0.5 %
Solution / drops, , Solution / drops - Ophthalmic, Liquid - Ophthalmic, Solution - Ophthalmic, Tablet, orally disintegrating, Liquid, Solution, Oral, Liquid - Oral, Solution - Oral, Ophthalmic, Liquid; Solution / drops - Ophthalmic, Liquid; Solution / drops, Tablet, orally disintegrating - Oral
Haematological disorders
30.0 mg, 10.0 mg/mL, 15.0 mg, 5.0 mg/mL, , 10.0 mg, 15.0 mg/mL, 1.25 mg/mL, 1.0 %, 0.125 %, 2.5 mg/mL, 2.3 mg/mL, 20.0 mg/mL, 25.0 mg/mL, 0.5 %
Solution / drops, , Solution / drops - Ophthalmic, Liquid - Ophthalmic, Solution - Ophthalmic, Tablet, orally disintegrating, Liquid, Solution, Oral, Liquid - Oral, Solution - Oral, Ophthalmic, Liquid; Solution / drops - Ophthalmic, Liquid; Solution / drops, Tablet, orally disintegrating - Oral
Allergic Conditions
30.0 mg, 10.0 mg/mL, 15.0 mg, 5.0 mg/mL, , 10.0 mg, 15.0 mg/mL, 1.25 mg/mL, 1.0 %, 0.125 %, 2.5 mg/mL, 2.3 mg/mL, 20.0 mg/mL, 25.0 mg/mL, 0.5 %
Solution / drops, , Solution / drops - Ophthalmic, Liquid - Ophthalmic, Solution - Ophthalmic, Tablet, orally disintegrating, Liquid, Solution, Oral, Liquid - Oral, Solution - Oral, Ophthalmic, Liquid; Solution / drops - Ophthalmic, Liquid; Solution / drops, Tablet, orally disintegrating - Oral
Endocrine Disorders
30.0 mg, 10.0 mg/mL, 15.0 mg, 5.0 mg/mL, , 10.0 mg, 15.0 mg/mL, 1.25 mg/mL, 1.0 %, 0.125 %, 2.5 mg/mL, 2.3 mg/mL, 20.0 mg/mL, 25.0 mg/mL, 0.5 %
Solution / drops, , Solution / drops - Ophthalmic, Liquid - Ophthalmic, Solution - Ophthalmic, Tablet, orally disintegrating, Liquid, Solution, Oral, Liquid - Oral, Solution - Oral, Ophthalmic, Liquid; Solution / drops - Ophthalmic, Liquid; Solution / drops, Tablet, orally disintegrating - Oral
Dermatological Disease
30.0 mg, 10.0 mg/mL, 15.0 mg, 5.0 mg/mL, , 10.0 mg, 15.0 mg/mL, 1.25 mg/mL, 1.0 %, 0.125 %, 2.5 mg/mL, 2.3 mg/mL, 20.0 mg/mL, 25.0 mg/mL, 0.5 %
Solution / drops, , Solution / drops - Ophthalmic, Liquid - Ophthalmic, Solution - Ophthalmic, Tablet, orally disintegrating, Liquid, Solution, Oral, Liquid - Oral, Solution - Oral, Ophthalmic, Liquid; Solution / drops - Ophthalmic, Liquid; Solution / drops, Tablet, orally disintegrating - Oral
Warnings
Orapred Odt has one contraindication, and so should not be utilized in combination with the conditions given in the following table.Orapred Odt ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Prednisolone Phosphate may interact with Toxoplasma Infections
Common Orapred Odt Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The serum concentration of Abemaciclib can be decreased when it is combined with Prednisolone phosphate.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be increased when combined with Prednisolone phosphate.
Aldesleukin
Major
The therapeutic efficacy of Aldesleukin can be decreased when used in combination with Prednisolone phosphate.
Alectinib
Major
The metabolism of Alectinib can be increased when combined with Prednisolone phosphate.
Alpelisib
Major
The metabolism of Alpelisib can be increased when combined with Prednisolone phosphate.
Orapred Odt Toxicity & Overdose RiskLimited information is available about the effects of an acute overdose. However, if someone has been taking too much of this drug for a long period of time, they may experience mental symptoms, a swollen face, abnormal fat deposits, and fluid retention. If someone has taken an oral overdose, they should have their stomach washed out or vomit immediately, followed by supportive treatment. If the overdose is chronic, reducing the dose or taking it every other day may help.
Orapred Odt Novel Uses: Which Conditions Have a Clinical Trial Featuring Orapred Odt?
115 active clinical trials are currently being conducted to assess the utility of Orapred Odt in providing Ocular Inflammation relief, Uveitis alleviation and Sympathetic Ophthalmia management.Condition
Clinical Trials
Trial Phases
Ocular Inflammation
2 Actively Recruiting
Phase 2, Phase 4
Uveitis
13 Actively Recruiting
Phase 2, Phase 3, Phase 4, Not Applicable
Ophthalmia, Sympathetic
0 Actively Recruiting
Neoplastic Disease
1 Actively Recruiting
Phase 1
Multiple Sclerosis
0 Actively Recruiting
Dermatological Disease
0 Actively Recruiting
Collagen Diseases
0 Actively Recruiting
Endocrine Disorders
0 Actively Recruiting
Haematological disorders
4 Actively Recruiting
Phase 2, Not Applicable
Temporal Arteritis
0 Actively Recruiting
Swollen feet or ankles
45 Actively Recruiting
Phase 1, Phase 2, Phase 4, Not Applicable, Early Phase 1, Phase 3
Urinary Tract Infection (UTI)
24 Actively Recruiting
Phase 2, Phase 1, Phase 4, Phase 3, Not Applicable
Respiratory Diseases
5 Actively Recruiting
Phase 4, Not Applicable
Gastroenteritis
28 Actively Recruiting
Phase 2, Not Applicable, Phase 3, Phase 1
Allergic Conditions
0 Actively Recruiting
Orapred Odt Reviews: What are patients saying about Orapred Odt?
5Patient Review
4/19/2008 My son has asthma and was having a lot of trouble with coughing. We tried this medicine and it worked great! Within two days, his cough was much better. And we didn't see any negative side effects, which is always a bonus.
4.7Patient Review
2/4/2009 My son's wheezing and coughing have rapidly improved since we started this treatment, which is great. It also seems to be helping with his eczema, which is a nice bonus. The only side effects we've noticed are increased appetite and some tummy trouble.
4.3Patient Review
5/21/2008 Though this drug usually works quickly, it unfortunately does not for my eight-year-old son. We often have to resort to breathing treatments in addition to the Orapred. Additionally, after about three days of use his personality changes quite a bit - he becomes more aggressive.
4Patient Review
3/7/2009 My toddler had croup and we tried this treatment. We were only supposed to give him two doses, but he turned into a total nightmare. He was destructive and wild. But, it did help with the "barking" cough and so far he's just been coughing regularly.
4Patient Review
4/27/2010 My son's side effects from this medication were tingling in his fingers and hyperactivity. While it was effective, I'm not sure if the trade-off is worth it for us.
3Patient Review
3/17/2009 My son was prescribed this for a chronic cough and congestion. I have noticed he is very thirsty, but I'm not sure if that's a normal side effect. He was initially hyper the first day, but okay the second. So far, we haven't seen any improvement.
2.7Patient Review
3/2/2009 My daughter has been taking this medication for four days now and while her cough has decreased somewhat, the side effects have not been worth it. She's experienced upset stomach, restlessness, sharp pains in her chest and limbs, and dizziness. We will not be using this again.
1Patient Review
1/13/2009 I'm four days into taking this medication and I haven't seen any improvement.
Patient Q&A Section about orapred odt
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is orapred and prednisone the same?
"Other common names for prednisone and prednisolone include Deltasone and Sterapred.
Some common brand names for prednisone include Prednisone Intensol and Rayos. Some common brand names for prednisolone include Flo-Pred, Pediapred, Orapred, and Orapred ODT."
Answered by AI
What is the generic name for orapred?
"Other names for the drug Prednisolone include Delta-Cortef, Prelone, and Pediapred. Prednisolone may also be referred to by its trade name, Orapred."
Answered by AI