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Stem Cell Addback for Leukemia
Study Summary
This trial found that adding back naive T cells to a stem cell transplant from a matched sibling donor may improve immune reconstitution and help decrease the risk of infections.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- My leukemia is at high risk of coming back or has already relapsed.My organs are healthy and I don't have infections, as per the bone marrow transplant guidelines.I am younger than 25 years old.I have had only one bone marrow transplant from a donor.I am over 18 and can consent, or my guardian has consented for me.I have a genetic disorder related to DNA repair, like Fanconi anemia.I don't have a matching donor for a stem cell transplant.I have Hodgkin lymphoma or a type of non-Burkitts, non-lymphoblastic lymphoma.I meet my hospital's health standards for treatment.
- Group 1: TBI regimen
- Group 2: TBI or busulfan regimen
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What is the limit to patient enrollment in this trial?
"Yes, the latest data on clinicaltrials.gov indicates that this research initiative has resumed their search for participants. This trial was first posted on March 1st 2019 and its most recent update happened on March 21st 2022; they are in need of 30 patients from a single medical centre."
Are researchers still accepting participants for this clinical experiment?
"Indeed, information accessible on clinicaltrials.gov confirms that this investigation is currently recruiting participants. Initially posted on March 1st 2019 and recently updated on March 21st 2022, the trial requires 30 volunteers across a single site."
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