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What is Ocuflox
OfloxacinThe Generic name of this drug
Treatment SummaryA synthetic fluoroquinolone is an antibiotic that works by stopping bacteria from replicating their DNA. This prevents the bacteria from reproducing and spreading, allowing the body to fight the infection.
Floxinis the brand name
Ocuflox Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Floxin
Ofloxacin
1990
149
Approved as Treatment by the FDA
Ofloxacin, also called Floxin, is approved by the FDA for 1 uses which include Urinary Tract Infection (UTI) .Urinary Tract Infection (UTI)
Effectiveness
How Ocuflox Affects PatientsOfloxacin is an antibiotic that works by stopping bacteria from copying their DNA. It attaches to an enzyme called DNA gyrase, which is needed for bacteria to reproduce, and is 100 times more powerful on bacterial DNA than on human DNA. Ofloxacin is effective against both Gram-positive and Gram-negative bacteria.
How Ocuflox works in the bodyOfloxacin interferes with the enzymes responsible for keeping DNA from becoming too tightly wound during replication. This prevents cells from dividing normally and helps to kill bacteria.
When to interrupt dosage
The quantity of Ocuflox is contingent upon the diagnosed condition, for instance Urethritis, Cervicitis and Urinary Tract Infection (UTI). The measure of dosage fluctuates as per the approach of delivery (e.g. Oral or Solution) illustrated in the table below.Condition
Dosage
Administration
Prostatitis
3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL
Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous
Diarrhea
3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL
Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous
Epididymitis
3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL
Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous
Gonorrhea
3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL
Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous
Otitis Media
3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL
Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous
Hansen's Disease
3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL
Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous
Cystitis
3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL
Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous
Urinary Tract Infection (UTI)
3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL
Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous
Pink Eye
3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL
Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous
Acute Coryza
3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL
Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous
Bacterial Infections
3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL
Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous
Community Acquired Pneumonia (CAP)
3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL
Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous
Acute Otitis Media (AOM)
3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL
Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous
Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB)
3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL
Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous
Cervicitis
3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL
Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous
Otitis Externa
3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL
Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous
Corneal Ulcer
3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL
Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous
Urethritis
3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL
Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous
Urinary tract infection
3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL
Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous
Spontaneous Bacterial Peritonitis (SBP)
3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL
Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous
Warnings
Ocuflox has two counter-indications, so it must not be consumed when dealing with the ailments listed in the following table.Ocuflox ContraindicationsCondition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Common Ocuflox Drug Interactions
Drug Name
Risk Level
Description
Amiodarone
Major
The risk or severity of QTc prolongation can be increased when Ofloxacin is combined with Amiodarone.
Amitriptyline
Major
Ofloxacin may increase the QTc-prolonging activities of Amitriptyline.
Anagrelide
Major
The risk or severity of QTc prolongation can be increased when Ofloxacin is combined with Anagrelide.
Arsenic trioxide
Major
The risk or severity of QTc prolongation can be increased when Ofloxacin is combined with Arsenic trioxide.
Artemether
Major
The risk or severity of QTc prolongation can be increased when Ofloxacin is combined with Artemether.
Ocuflox Toxicity & Overdose RiskThe lowest toxic dose of the drug in mice, when given orally, has been found to be 5450mg/kg.
Ocuflox Novel Uses: Which Conditions Have a Clinical Trial Featuring Ocuflox?
Presently, 46 active studies are underway to assess the potential of Ocuflox in providing relief from Corneal Ulcers, Acute Coryza and Otitis Media.Condition
Clinical Trials
Trial Phases
Epididymitis
0 Actively Recruiting
Pink Eye
6 Actively Recruiting
Phase 4, Phase 3, Not Applicable, Phase 2
Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB)
0 Actively Recruiting
Prostatitis
3 Actively Recruiting
Not Applicable, Phase 4
Acute Otitis Media (AOM)
3 Actively Recruiting
Not Applicable
Urinary Tract Infection (UTI)
24 Actively Recruiting
Phase 2, Phase 1, Phase 4, Phase 3, Not Applicable
Spontaneous Bacterial Peritonitis (SBP)
0 Actively Recruiting
Otitis Media
0 Actively Recruiting
Otitis Externa
0 Actively Recruiting
Corneal Ulcer
0 Actively Recruiting
Gonorrhea
0 Actively Recruiting
Urethritis
0 Actively Recruiting
Hansen's Disease
0 Actively Recruiting
Bacterial Infections
1 Actively Recruiting
Phase 4
Acute Coryza
0 Actively Recruiting
Cervicitis
1 Actively Recruiting
Not Applicable
Cystitis
0 Actively Recruiting
Community Acquired Pneumonia (CAP)
1 Actively Recruiting
Not Applicable
Urinary tract infection
2 Actively Recruiting
Phase 2, Phase 3
Diarrhea
0 Actively Recruiting
Ocuflox Reviews: What are patients saying about Ocuflox?
2Patient Review
10/29/2016 My eye inflammation actually got worse after the second day of using this treatment.
Patient Q&A Section about ocuflox
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Ocuflox a steroid?
"Tobradex and Floxin both treat bacterial eye infections, but Tobradex also contains a steroid."
Answered by AI
Is Ocuflox used for pink eye?
"Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here.
Ofloxacin eye drops are used to kill bacteria that cause bacterial conjunctivitis (pink eye). The eye drops come in different forms and brand names."
Answered by AI
What is the generic name for Ocuflox?
"Ofloxacin is an antibiotic. It treats bacterial infections of the eye.
This medication is used to treat bacterial eye infections. Ofloxacin belongs to a class of drugs called quinolone antibiotics. It works by stopping the growth of bacteria."
Answered by AI
How long does Ocuflox take to work?
"When Ocuflox (ofloxacin) is placed directly on an infection or ulcer, it begins to work immediately. For pink eye, symptoms should start to improve within a few days. With corneal ulcers, it typically takes around 11 days for the ulcer to disappear."
Answered by AI