Ocuflox

Corneal Ulcer, Gonorrhea, Urinary Tract Infection (UTI) + 17 more
Treatment
1 FDA approval
20 Active Studies for Ocuflox

What is Ocuflox

OfloxacinThe Generic name of this drug
Treatment SummaryA synthetic fluoroquinolone is an antibiotic that works by stopping bacteria from replicating their DNA. This prevents the bacteria from reproducing and spreading, allowing the body to fight the infection.
Floxinis the brand name
Ocuflox Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Floxin
Ofloxacin
1990
148

Approved as Treatment by the FDA

Ofloxacin, also called Floxin, is approved by the FDA for 1 uses which include Urinary Tract Infection (UTI) .
Urinary Tract Infection (UTI)

Effectiveness

How Ocuflox Affects PatientsOfloxacin is an antibiotic that works by stopping bacteria from copying their DNA. It attaches to an enzyme called DNA gyrase, which is needed for bacteria to reproduce, and is 100 times more powerful on bacterial DNA than on human DNA. Ofloxacin is effective against both Gram-positive and Gram-negative bacteria.
How Ocuflox works in the bodyOfloxacin interferes with the enzymes responsible for keeping DNA from becoming too tightly wound during replication. This prevents cells from dividing normally and helps to kill bacteria.

When to interrupt dosage

The quantity of Ocuflox is contingent upon the diagnosed condition, for instance Urethritis, Cervicitis and Urinary Tract Infection (UTI). The measure of dosage fluctuates as per the approach of delivery (e.g. Oral or Solution) illustrated in the table below.
Condition
Dosage
Administration
Acute Coryza
, 20.0 mg/mL, 3.0 mg/mL, 200.0 mg, 400.0 mg, 300.0 mg, 0.3 %, 600.0 mg
Oral, Solution, Tablet, , Tablet - Oral, Tablet, coated, Solution - Auricular (otic), Ophthalmic, Tablet, coated - Oral, Solution - Ophthalmic, Solution / drops - Ophthalmic, Intravenous, Tablet, film coated, Solution / drops, Liquid, Tablet, film coated - Oral, Liquid - Intravenous, Auricular (otic), Solution / drops - Auricular (otic)
Otitis Media
, 20.0 mg/mL, 3.0 mg/mL, 200.0 mg, 400.0 mg, 300.0 mg, 0.3 %, 600.0 mg
Oral, Solution, Tablet, , Tablet - Oral, Tablet, coated, Solution - Auricular (otic), Ophthalmic, Tablet, coated - Oral, Solution - Ophthalmic, Solution / drops - Ophthalmic, Intravenous, Tablet, film coated, Solution / drops, Liquid, Tablet, film coated - Oral, Liquid - Intravenous, Auricular (otic), Solution / drops - Auricular (otic)
Cervicitis
, 20.0 mg/mL, 3.0 mg/mL, 200.0 mg, 400.0 mg, 300.0 mg, 0.3 %, 600.0 mg
Oral, Solution, Tablet, , Tablet - Oral, Tablet, coated, Solution - Auricular (otic), Ophthalmic, Tablet, coated - Oral, Solution - Ophthalmic, Solution / drops - Ophthalmic, Intravenous, Tablet, film coated, Solution / drops, Liquid, Tablet, film coated - Oral, Liquid - Intravenous, Auricular (otic), Solution / drops - Auricular (otic)
Epididymitis
, 20.0 mg/mL, 3.0 mg/mL, 200.0 mg, 400.0 mg, 300.0 mg, 0.3 %, 600.0 mg
Oral, Solution, Tablet, , Tablet - Oral, Tablet, coated, Solution - Auricular (otic), Ophthalmic, Tablet, coated - Oral, Solution - Ophthalmic, Solution / drops - Ophthalmic, Intravenous, Tablet, film coated, Solution / drops, Liquid, Tablet, film coated - Oral, Liquid - Intravenous, Auricular (otic), Solution / drops - Auricular (otic)
Spontaneous Bacterial Peritonitis (SBP)
, 20.0 mg/mL, 3.0 mg/mL, 200.0 mg, 400.0 mg, 300.0 mg, 0.3 %, 600.0 mg
Oral, Solution, Tablet, , Tablet - Oral, Tablet, coated, Solution - Auricular (otic), Ophthalmic, Tablet, coated - Oral, Solution - Ophthalmic, Solution / drops - Ophthalmic, Intravenous, Tablet, film coated, Solution / drops, Liquid, Tablet, film coated - Oral, Liquid - Intravenous, Auricular (otic), Solution / drops - Auricular (otic)
Corneal Ulcer
, 20.0 mg/mL, 3.0 mg/mL, 200.0 mg, 400.0 mg, 300.0 mg, 0.3 %, 600.0 mg
Oral, Solution, Tablet, , Tablet - Oral, Tablet, coated, Solution - Auricular (otic), Ophthalmic, Tablet, coated - Oral, Solution - Ophthalmic, Solution / drops - Ophthalmic, Intravenous, Tablet, film coated, Solution / drops, Liquid, Tablet, film coated - Oral, Liquid - Intravenous, Auricular (otic), Solution / drops - Auricular (otic)
Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB)
, 20.0 mg/mL, 3.0 mg/mL, 200.0 mg, 400.0 mg, 300.0 mg, 0.3 %, 600.0 mg
Oral, Solution, Tablet, , Tablet - Oral, Tablet, coated, Solution - Auricular (otic), Ophthalmic, Tablet, coated - Oral, Solution - Ophthalmic, Solution / drops - Ophthalmic, Intravenous, Tablet, film coated, Solution / drops, Liquid, Tablet, film coated - Oral, Liquid - Intravenous, Auricular (otic), Solution / drops - Auricular (otic)
Gonorrhea
, 20.0 mg/mL, 3.0 mg/mL, 200.0 mg, 400.0 mg, 300.0 mg, 0.3 %, 600.0 mg
Oral, Solution, Tablet, , Tablet - Oral, Tablet, coated, Solution - Auricular (otic), Ophthalmic, Tablet, coated - Oral, Solution - Ophthalmic, Solution / drops - Ophthalmic, Intravenous, Tablet, film coated, Solution / drops, Liquid, Tablet, film coated - Oral, Liquid - Intravenous, Auricular (otic), Solution / drops - Auricular (otic)
Urinary Tract Infection (UTI)
, 20.0 mg/mL, 3.0 mg/mL, 200.0 mg, 400.0 mg, 300.0 mg, 0.3 %, 600.0 mg
Oral, Solution, Tablet, , Tablet - Oral, Tablet, coated, Solution - Auricular (otic), Ophthalmic, Tablet, coated - Oral, Solution - Ophthalmic, Solution / drops - Ophthalmic, Intravenous, Tablet, film coated, Solution / drops, Liquid, Tablet, film coated - Oral, Liquid - Intravenous, Auricular (otic), Solution / drops - Auricular (otic)
Urethritis
, 20.0 mg/mL, 3.0 mg/mL, 200.0 mg, 400.0 mg, 300.0 mg, 0.3 %, 600.0 mg
Oral, Solution, Tablet, , Tablet - Oral, Tablet, coated, Solution - Auricular (otic), Ophthalmic, Tablet, coated - Oral, Solution - Ophthalmic, Solution / drops - Ophthalmic, Intravenous, Tablet, film coated, Solution / drops, Liquid, Tablet, film coated - Oral, Liquid - Intravenous, Auricular (otic), Solution / drops - Auricular (otic)
Community Acquired Pneumonia (CAP)
, 20.0 mg/mL, 3.0 mg/mL, 200.0 mg, 400.0 mg, 300.0 mg, 0.3 %, 600.0 mg
Oral, Solution, Tablet, , Tablet - Oral, Tablet, coated, Solution - Auricular (otic), Ophthalmic, Tablet, coated - Oral, Solution - Ophthalmic, Solution / drops - Ophthalmic, Intravenous, Tablet, film coated, Solution / drops, Liquid, Tablet, film coated - Oral, Liquid - Intravenous, Auricular (otic), Solution / drops - Auricular (otic)
Urinary tract infection
, 20.0 mg/mL, 3.0 mg/mL, 200.0 mg, 400.0 mg, 300.0 mg, 0.3 %, 600.0 mg
Oral, Solution, Tablet, , Tablet - Oral, Tablet, coated, Solution - Auricular (otic), Ophthalmic, Tablet, coated - Oral, Solution - Ophthalmic, Solution / drops - Ophthalmic, Intravenous, Tablet, film coated, Solution / drops, Liquid, Tablet, film coated - Oral, Liquid - Intravenous, Auricular (otic), Solution / drops - Auricular (otic)
Diarrhea
, 20.0 mg/mL, 3.0 mg/mL, 200.0 mg, 400.0 mg, 300.0 mg, 0.3 %, 600.0 mg
Oral, Solution, Tablet, , Tablet - Oral, Tablet, coated, Solution - Auricular (otic), Ophthalmic, Tablet, coated - Oral, Solution - Ophthalmic, Solution / drops - Ophthalmic, Intravenous, Tablet, film coated, Solution / drops, Liquid, Tablet, film coated - Oral, Liquid - Intravenous, Auricular (otic), Solution / drops - Auricular (otic)
Bacterial Infections
, 20.0 mg/mL, 3.0 mg/mL, 200.0 mg, 400.0 mg, 300.0 mg, 0.3 %, 600.0 mg
Oral, Solution, Tablet, , Tablet - Oral, Tablet, coated, Solution - Auricular (otic), Ophthalmic, Tablet, coated - Oral, Solution - Ophthalmic, Solution / drops - Ophthalmic, Intravenous, Tablet, film coated, Solution / drops, Liquid, Tablet, film coated - Oral, Liquid - Intravenous, Auricular (otic), Solution / drops - Auricular (otic)
Hansen's Disease
, 20.0 mg/mL, 3.0 mg/mL, 200.0 mg, 400.0 mg, 300.0 mg, 0.3 %, 600.0 mg
Oral, Solution, Tablet, , Tablet - Oral, Tablet, coated, Solution - Auricular (otic), Ophthalmic, Tablet, coated - Oral, Solution - Ophthalmic, Solution / drops - Ophthalmic, Intravenous, Tablet, film coated, Solution / drops, Liquid, Tablet, film coated - Oral, Liquid - Intravenous, Auricular (otic), Solution / drops - Auricular (otic)
Cystitis
, 20.0 mg/mL, 3.0 mg/mL, 200.0 mg, 400.0 mg, 300.0 mg, 0.3 %, 600.0 mg
Oral, Solution, Tablet, , Tablet - Oral, Tablet, coated, Solution - Auricular (otic), Ophthalmic, Tablet, coated - Oral, Solution - Ophthalmic, Solution / drops - Ophthalmic, Intravenous, Tablet, film coated, Solution / drops, Liquid, Tablet, film coated - Oral, Liquid - Intravenous, Auricular (otic), Solution / drops - Auricular (otic)
Acute Otitis Media (AOM)
, 20.0 mg/mL, 3.0 mg/mL, 200.0 mg, 400.0 mg, 300.0 mg, 0.3 %, 600.0 mg
Oral, Solution, Tablet, , Tablet - Oral, Tablet, coated, Solution - Auricular (otic), Ophthalmic, Tablet, coated - Oral, Solution - Ophthalmic, Solution / drops - Ophthalmic, Intravenous, Tablet, film coated, Solution / drops, Liquid, Tablet, film coated - Oral, Liquid - Intravenous, Auricular (otic), Solution / drops - Auricular (otic)
Pink Eye
, 20.0 mg/mL, 3.0 mg/mL, 200.0 mg, 400.0 mg, 300.0 mg, 0.3 %, 600.0 mg
Oral, Solution, Tablet, , Tablet - Oral, Tablet, coated, Solution - Auricular (otic), Ophthalmic, Tablet, coated - Oral, Solution - Ophthalmic, Solution / drops - Ophthalmic, Intravenous, Tablet, film coated, Solution / drops, Liquid, Tablet, film coated - Oral, Liquid - Intravenous, Auricular (otic), Solution / drops - Auricular (otic)
Otitis Externa
, 20.0 mg/mL, 3.0 mg/mL, 200.0 mg, 400.0 mg, 300.0 mg, 0.3 %, 600.0 mg
Oral, Solution, Tablet, , Tablet - Oral, Tablet, coated, Solution - Auricular (otic), Ophthalmic, Tablet, coated - Oral, Solution - Ophthalmic, Solution / drops - Ophthalmic, Intravenous, Tablet, film coated, Solution / drops, Liquid, Tablet, film coated - Oral, Liquid - Intravenous, Auricular (otic), Solution / drops - Auricular (otic)
Prostatitis
, 20.0 mg/mL, 3.0 mg/mL, 200.0 mg, 400.0 mg, 300.0 mg, 0.3 %, 600.0 mg
Oral, Solution, Tablet, , Tablet - Oral, Tablet, coated, Solution - Auricular (otic), Ophthalmic, Tablet, coated - Oral, Solution - Ophthalmic, Solution / drops - Ophthalmic, Intravenous, Tablet, film coated, Solution / drops, Liquid, Tablet, film coated - Oral, Liquid - Intravenous, Auricular (otic), Solution / drops - Auricular (otic)

Warnings

Ocuflox has two counter-indications, so it must not be consumed when dealing with the ailments listed in the following table.Ocuflox Contraindications
Condition
Risk Level
Notes
Toxoplasma Infections
Do Not Combine
Toxoplasma Infections
Do Not Combine
There are 20 known major drug interactions with Ocuflox.
Common Ocuflox Drug Interactions
Drug Name
Risk Level
Description
Amiodarone
Major
The risk or severity of QTc prolongation can be increased when Ofloxacin is combined with Amiodarone.
Amitriptyline
Major
Ofloxacin may increase the QTc-prolonging activities of Amitriptyline.
Anagrelide
Major
The risk or severity of QTc prolongation can be increased when Ofloxacin is combined with Anagrelide.
Arsenic trioxide
Major
The risk or severity of QTc prolongation can be increased when Ofloxacin is combined with Arsenic trioxide.
Artemether
Major
The risk or severity of QTc prolongation can be increased when Ofloxacin is combined with Artemether.
Ocuflox Toxicity & Overdose RiskThe lowest toxic dose of the drug in mice, when given orally, has been found to be 5450mg/kg.

Ocuflox Novel Uses: Which Conditions Have a Clinical Trial Featuring Ocuflox?

Presently, 46 active studies are underway to assess the potential of Ocuflox in providing relief from Corneal Ulcers, Acute Coryza and Otitis Media.
Condition
Clinical Trials
Trial Phases
Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB)
0 Actively Recruiting
Cervicitis
1 Actively Recruiting
Not Applicable
Community Acquired Pneumonia (CAP)
1 Actively Recruiting
Not Applicable
Acute Coryza
0 Actively Recruiting
Epididymitis
0 Actively Recruiting
Cystitis
0 Actively Recruiting
Corneal Ulcer
0 Actively Recruiting
Urethritis
0 Actively Recruiting
Otitis Media
0 Actively Recruiting
Bacterial Infections
1 Actively Recruiting
Phase 4
Otitis Externa
0 Actively Recruiting
Spontaneous Bacterial Peritonitis (SBP)
0 Actively Recruiting
Acute Otitis Media (AOM)
1 Actively Recruiting
Not Applicable
Diarrhea
0 Actively Recruiting
Gonorrhea
0 Actively Recruiting
Hansen's Disease
0 Actively Recruiting
Pink Eye
10 Actively Recruiting
Phase 4, Phase 3, Phase 1, Phase 2, Not Applicable
Urinary tract infection
2 Actively Recruiting
Phase 2, Phase 3
Prostatitis
4 Actively Recruiting
Phase 2, Not Applicable, Phase 4
Urinary Tract Infection (UTI)
25 Actively Recruiting
Phase 2, Phase 1, Phase 4, Phase 3, Not Applicable

Ocuflox Reviews: What are patients saying about Ocuflox?

2Patient Review
10/29/2016
Ocuflox for Pink Eye from Bacterial Infection
My eye inflammation actually got worse after the second day of using this treatment.

Patient Q&A Section about ocuflox

Is Ocuflox a steroid?

"Tobradex and Floxin both treat bacterial eye infections, but Tobradex also contains a steroid." - Anonymous Online Contributor

Unverified Answer

Is Ocuflox used for pink eye?

"Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here.

Ofloxacin eye drops are used to kill bacteria that cause bacterial conjunctivitis (pink eye). The eye drops come in different forms and brand names." - Anonymous Online Contributor

Unverified Answer

What is the generic name for Ocuflox?

"Ofloxacin is an antibiotic. It treats bacterial infections of the eye.

This medication is used to treat bacterial eye infections. Ofloxacin belongs to a class of drugs called quinolone antibiotics. It works by stopping the growth of bacteria." - Anonymous Online Contributor

Unverified Answer

How long does Ocuflox take to work?

"When Ocuflox (ofloxacin) is placed directly on an infection or ulcer, it begins to work immediately. For pink eye, symptoms should start to improve within a few days. With corneal ulcers, it typically takes around 11 days for the ulcer to disappear." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Clinical Trials for Ocuflox

Have you considered Ocuflox clinical trials? We made a collection of clinical trials featuring Ocuflox, we think they might fit your search criteria.
Have you considered Ocuflox clinical trials? We made a collection of clinical trials featuring Ocuflox, we think they might fit your search criteria.
Have you considered Ocuflox clinical trials? We made a collection of clinical trials featuring Ocuflox, we think they might fit your search criteria.