Personalized Lifestyle Management for Aging

Overseen By Susan B. Racette, PhD

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Arizona State University

Disqualifiers: Pregnancy, Under 50, Over 85, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 6

Duration: 12 weeks

25 Participants Needed

Trial Summary

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It focuses on lifestyle changes like exercise and nutrition.

What data supports the effectiveness of the treatment Personalized Lifestyle Management for Aging?

Research shows that programs like the Aging Mastery Program, which focus on lifestyle management, have improved physical activity and planning for future care in older adults. This suggests that personalized lifestyle interventions can be effective in promoting healthy aging. ^{1 2 3 4 5}

Is the Personalized Lifestyle Management for Aging treatment safe for humans?

The available research on similar programs, like 'I am Active' and the Aging Mastery Program, suggests that these lifestyle interventions are generally safe for humans, focusing on promoting physical activity, healthy eating, and mental well-being without reported safety concerns. ^{1 3 6 7 8}

How is the Personalized Lifestyle Management treatment for aging different from other treatments?

The Personalized Lifestyle Management treatment is unique because it focuses on creating a tailored plan that integrates various lifestyle strategies, such as physical activity, nutrition, and cognitive exercises, to promote healthy aging. Unlike standard treatments, it emphasizes individual customization and self-management to improve overall quality of life and address specific aging challenges. ^{1 3 6 9 10}

What is the purpose of this trial?

The goal of this clinical trial study is to evaluate the impact of a personalized lifestyle intervention on improving healthspan. The primary questions of interest are whether the personalized intervention will result in improvements in muscle function, immune function, and cognitive function in adults aged 50-85 years. Participants will complete baseline assessments, receive an individualized intervention plan for approximately 3 months, and then complete post-intervention assessments. The intervention includes an exercise plan, nutrition recommendations, and general lifestyle goals that will be personalized to each participant.

Eligibility Criteria

This trial is for adults aged 50-85 who want to improve their health as they age. It's not suitable for those with conditions that might limit participation or adherence to the lifestyle changes.

Inclusion Criteria

Non-smoking

English speaking

Owns a smart phone

Exclusion Criteria

Pregnant women

Prisoners

I am between 50 and 85 years old.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Baseline Assessment

Participants complete baseline assessments to evaluate initial health metrics

1 week

1 visit (in-person)

Treatment

Participants receive an individualized lifestyle intervention plan including exercise, nutrition, and lifestyle goals for approximately 3 months

12 weeks

4 visits (in-person), 2 visits (virtual)

Post-intervention Assessment

Participants complete assessments to evaluate changes in health metrics after the intervention

1 week

1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

Treatment Details

Interventions

• Lifestyle Management

Trial Overview The study tests a personalized lifestyle program aimed at enhancing muscle, immune, and cognitive functions in older adults. Participants will follow an individualized plan of exercise, diet, and lifestyle adjustments for about 3 months.

Participant Groups

Group I: Lifestyle Intervention Experimental Treatment 1 Intervention

All participants will receive an intervention.

Who Is Running the Clinical Trial?

Arizona State University

Lead Sponsor

Trials

311

Recruited

109,000+

Findings from Research

The Aging Mastery Program® (AMP) was tested in ten senior centers and showed statistically significant improvements in physical activity and advanced care planning among older adults.

These results indicate that AMP is an effective, evidence-based intervention that can enhance general health and quality of life for seniors, supporting their active management of aging.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Assessing the Effectiveness of the Aging Mastery Program. Ferretti, L., McCallion, P., McDonald, E., et al.[2023]

Lifestyle modifications are important for reducing the risk of chronic diseases, yet healthcare providers often spend minimal time discussing these changes with patients.

The SMART-EST goal framework is proposed as an effective method to enhance discussions about lifestyle medicine and create personalized action plans for patients to improve their health behaviors.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Using the SMART-EST Goals in Lifestyle Medicine Prescription. White, ND., Bautista, V., Lenz, T., et al.[2021]

The Integrated Health Management Model Project (OPCHMP) significantly improved adherence to healthy lifestyle behaviors among 637 elderly participants over a 2-year period compared to usual care.

Participants in the intervention group also reported better health indicators, highlighting the effectiveness of the OPCHMP in promoting healthier lifestyles in the elderly.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

The effect of older-person centered and integrated health management model on multiple lifestyle behaviors: A randomized controlled trial from China. Zhang, M., Chao, J., Li, D., et al.[2019]

Long-term adherence to lifestyle medicine is crucial for preventing and treating lifestyle diseases, as these conditions require ongoing management.

Healthcare providers should focus on helping patients develop sustainable routines for incorporating health recommendations gradually, rather than expecting immediate adherence, to improve long-term success.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

The Importance of Creating Habits and Routine. Arlinghaus, KR., Johnston, CA.[2023]

The importance of promoting healthy aging is increasingly critical due to the aging US population and rising lifestyle diseases, highlighting a need for geriatricians to focus on this area.

Lifestyle medicine provides an evidence-based approach that aligns with geriatrics, offering tools and strategies to enhance healthy aging throughout a person's life.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

How Do Geriatric Principles Inform Healthy Aging? Muniak, JD., Mulhausen, P.[2021]

The 'I am Active' program significantly improved physical activity, nutrition, cognitive performance, and quality of life in 64 healthy adults aged 60 and older, compared to a control group.

Improvements in self-efficacy for physical activity and nutrition, as well as processing speed, were maintained even at a 6-month follow-up, indicating lasting benefits of the program.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

"I am active": effects of a program to promote active aging. Mendoza-Ruvalcaba, NM., Arias-Merino, ED.[2022]

The Healthy Lifetime (HL) health coaching program significantly improved health habits in participants aged 50 and older with chronic conditions after 8 weeks, and these improvements were maintained at 20 weeks, indicating its efficacy in promoting healthier lifestyles.

Participants in the HL group also showed improved self-care agency, particularly those with high blood pressure, although this improvement did not last beyond the initial 8 weeks, highlighting the need for ongoing support in managing chronic conditions.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

A randomized trial of a theory-driven model of health coaching for older adults: short-term and sustained outcomes. Potempa, K., Calarco, M., Flaherty-Robb, M., et al.[2023]

The integrated health management program (IHMP) significantly improved physical health in older Korean women, with notable decreases in body mass index and increases in skeletal muscle mass after 12 weeks of intervention.

Participants also experienced improvements in mental health, as evidenced by reduced depression levels and increased social support, highlighting the program's comprehensive benefits for successful aging.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Effect of an Integrated Health Management Program Based on Successful Aging in Korean Women. Ahn, O., Cha, HG., Chang, SJ., et al.[2022]

A survey of 386 adults aged 55 and older revealed that their preferences for wellness program activities are significantly influenced by their current healthy behaviors, gender, and age.

Interestingly, factors like BMI, chronic conditions, and self-rated health did not impact their preferences, suggesting that tailoring programs to align with the interests of aging adults can enhance engagement and effectiveness.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Aging Adults' Preferences for Wellness Program Activities and Delivery Characteristics: A Cross-Sectional Survey. Talley, KMC., Cheung, C., Mathiason, MA., et al.[2022]

Lifestyle Management Programs© (LMPs) developed by occupational therapists for individuals with multiple sclerosis (MS) are flexible and adaptable, helping clients manage fluctuating physical, sensory, and cognitive symptoms effectively.

Client feedback indicates that LMPs are effective in helping individuals with MS sustain meaningful activities and achieve personal goals, with formal outcome measures currently being explored to further validate their efficacy.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Developing and implementing lifestyle management programs© with people with multiple sclerosis. Roessler, C., Barling, J., Dephoff, M., et al.[2013]

References

1. Switzerland pubmed.ncbi.nlm.nih.gov

Assessing the Effectiveness of the Aging Mastery Program. [2023]

2. United States pubmed.ncbi.nlm.nih.gov

Using the SMART-EST Goals in Lifestyle Medicine Prescription. [2021]

3. Netherlands pubmed.ncbi.nlm.nih.gov

The effect of older-person centered and integrated health management model on multiple lifestyle behaviors: A randomized controlled trial from China. [2019]

4. United States pubmed.ncbi.nlm.nih.gov

The Importance of Creating Habits and Routine. [2023]

5. United States pubmed.ncbi.nlm.nih.gov

How Do Geriatric Principles Inform Healthy Aging? [2021]

6. New Zealand pubmed.ncbi.nlm.nih.gov

"I am active": effects of a program to promote active aging. [2022]

7. England pubmed.ncbi.nlm.nih.gov

A randomized trial of a theory-driven model of health coaching for older adults: short-term and sustained outcomes. [2023]

8. United States pubmed.ncbi.nlm.nih.gov

Effect of an Integrated Health Management Program Based on Successful Aging in Korean Women. [2022]

9. United States pubmed.ncbi.nlm.nih.gov

Aging Adults' Preferences for Wellness Program Activities and Delivery Characteristics: A Cross-Sectional Survey. [2022]

10. England pubmed.ncbi.nlm.nih.gov

Developing and implementing lifestyle management programs© with people with multiple sclerosis. [2013]