Personalized Lifestyle Management for Aging

Overseen By Judith Klein-Seetharaman, PhD

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Arizona State University

Disqualifiers: Pregnancy, Under 50, Over 85, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 6

Duration: 12 weeks

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores how personalized lifestyle changes might improve health aspects such as muscle strength, immune health, and brain function in adults. Participants receive a tailored plan that includes exercise, diet tips, and lifestyle goals for about three months. The study aims to determine if these personalized plans lead to better overall health. Individuals between 50 and 85 years old, who can walk without assistance and own a smartphone, might be suitable for this trial. As an unphased trial, this study offers participants the chance to contribute to innovative research that could enhance their health and well-being.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It focuses on lifestyle changes like exercise and nutrition.

What prior data suggests that this personalized lifestyle intervention is safe for improving healthspan?

Research shows that lifestyle changes, such as regular exercise and healthy eating, are safe and beneficial for older adults. Studies have found that these changes can reduce the risk of diseases like heart issues, high blood pressure, diabetes, and some cancers. They also enhance overall health and improve well-being as people age.

Previous research suggests that personalized lifestyle programs are generally well-received. Participants in similar studies have not reported serious side effects. Instead, many notice positive changes in their health and well-being. This makes lifestyle management a promising option for those seeking to improve their quality of life as they age. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about the Personalized Lifestyle Management for Aging because it offers a tailored approach to managing health as we age, focusing on individual habits and needs rather than a one-size-fits-all solution. Unlike standard options that often involve medications or generic advice, this intervention emphasizes personalized strategies that incorporate diet, exercise, and stress management specifically adjusted to each person's lifestyle and health status. By targeting the root causes of aging-related health issues, like inactivity and poor nutrition, this approach has the potential to improve overall well-being and quality of life without the side effects associated with many traditional treatments.

What evidence suggests that this lifestyle management plan is effective for improving healthspan?

Research has shown that personalized lifestyle changes can improve health in older adults. One study found that a three-month program, including exercise, healthy eating, and mental wellness sessions, improved participants' health. Another study demonstrated that these programs could slow aging by reducing cellular damage. Encouraging healthy habits and self-care improves overall health as people age. These findings support the idea that personalized lifestyle management, which all participants in this trial will receive, can enhance muscle strength, immune health, and brain function in older adults. ^{1 2 6 7 8}

Are You a Good Fit for This Trial?

This trial is for adults aged 50-85 who want to improve their health as they age. It's not suitable for those with conditions that might limit participation or adherence to the lifestyle changes.

Inclusion Criteria

Non-smoking

English speaking

Owns a smart phone

Exclusion Criteria

Pregnant women

Prisoners

I am between 50 and 85 years old.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Baseline Assessment

Participants complete baseline assessments to evaluate initial health metrics

1 week

1 visit (in-person)

Treatment

Participants receive an individualized lifestyle intervention plan including exercise, nutrition, and lifestyle goals for approximately 3 months

12 weeks

4 visits (in-person), 2 visits (virtual)

Post-intervention Assessment

Participants complete assessments to evaluate changes in health metrics after the intervention

1 week

1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

• Lifestyle Management

Trial Overview

The study tests a personalized lifestyle program aimed at enhancing muscle, immune, and cognitive functions in older adults. Participants will follow an individualized plan of exercise, diet, and lifestyle adjustments for about 3 months.

How Is the Trial Designed?

Group I: Lifestyle Intervention Experimental Treatment 1 Intervention

All participants will receive an intervention.

Who Is Running the Clinical Trial?

Arizona State University

Lead Sponsor

Trials

311

Recruited

109,000+

Published Research Related to This Trial

The Integrated Health Management Model Project (OPCHMP) significantly improved adherence to healthy lifestyle behaviors among 637 elderly participants over a 2-year period compared to usual care.

Participants in the intervention group also reported better health indicators, highlighting the effectiveness of the OPCHMP in promoting healthier lifestyles in the elderly.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

The effect of older-person centered and integrated health management model on multiple lifestyle behaviors: A randomized controlled trial from China. Zhang, M., Chao, J., Li, D., et al.[2019]

Long-term adherence to lifestyle medicine is crucial for preventing and treating lifestyle diseases, as these conditions require ongoing management.

Healthcare providers should focus on helping patients develop sustainable routines for incorporating health recommendations gradually, rather than expecting immediate adherence, to improve long-term success.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

The Importance of Creating Habits and Routine. Arlinghaus, KR., Johnston, CA.[2023]

A survey of 386 adults aged 55 and older revealed that their preferences for wellness program activities are significantly influenced by their current healthy behaviors, gender, and age.

Interestingly, factors like BMI, chronic conditions, and self-rated health did not impact their preferences, suggesting that tailoring programs to align with the interests of aging adults can enhance engagement and effectiveness.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Aging Adults' Preferences for Wellness Program Activities and Delivery Characteristics: A Cross-Sectional Survey. Talley, KMC., Cheung, C., Mathiason, MA., et al.[2022]

The Aging Mastery Program® (AMP) was tested in ten senior centers and showed statistically significant improvements in physical activity and advanced care planning among older adults.

These results indicate that AMP is an effective, evidence-based intervention that can enhance general health and quality of life for seniors, supporting their active management of aging.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Assessing the Effectiveness of the Aging Mastery Program. Ferretti, L., McCallion, P., McDonald, E., et al.[2023]

The importance of promoting healthy aging is increasingly critical due to the aging US population and rising lifestyle diseases, highlighting a need for geriatricians to focus on this area.

Lifestyle medicine provides an evidence-based approach that aligns with geriatrics, offering tools and strategies to enhance healthy aging throughout a person's life.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

How Do Geriatric Principles Inform Healthy Aging? Muniak, JD., Mulhausen, P.[2021]

The 'I am Active' program significantly improved physical activity, nutrition, cognitive performance, and quality of life in 64 healthy adults aged 60 and older, compared to a control group.

Improvements in self-efficacy for physical activity and nutrition, as well as processing speed, were maintained even at a 6-month follow-up, indicating lasting benefits of the program.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

"I am active": effects of a program to promote active aging. Mendoza-Ruvalcaba, NM., Arias-Merino, ED.[2022]

The integrated health management program (IHMP) significantly improved physical health in older Korean women, with notable decreases in body mass index and increases in skeletal muscle mass after 12 weeks of intervention.

Participants also experienced improvements in mental health, as evidenced by reduced depression levels and increased social support, highlighting the program's comprehensive benefits for successful aging.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Effect of an Integrated Health Management Program Based on Successful Aging in Korean Women. Ahn, O., Cha, HG., Chang, SJ., et al.[2022]

Lifestyle modifications are important for reducing the risk of chronic diseases, yet healthcare providers often spend minimal time discussing these changes with patients.

The SMART-EST goal framework is proposed as an effective method to enhance discussions about lifestyle medicine and create personalized action plans for patients to improve their health behaviors.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Using the SMART-EST Goals in Lifestyle Medicine Prescription. White, ND., Bautista, V., Lenz, T., et al.[2021]

Lifestyle Management Programs© (LMPs) developed by occupational therapists for individuals with multiple sclerosis (MS) are flexible and adaptable, helping clients manage fluctuating physical, sensory, and cognitive symptoms effectively.

Client feedback indicates that LMPs are effective in helping individuals with MS sustain meaningful activities and achieve personal goals, with formal outcome measures currently being explored to further validate their efficacy.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Developing and implementing lifestyle management programs© with people with multiple sclerosis. Roessler, C., Barling, J., Dephoff, M., et al.[2013]

The Healthy Lifetime (HL) health coaching program significantly improved health habits in participants aged 50 and older with chronic conditions after 8 weeks, and these improvements were maintained at 20 weeks, indicating its efficacy in promoting healthier lifestyles.

Participants in the HL group also showed improved self-care agency, particularly those with high blood pressure, although this improvement did not last beyond the initial 8 weeks, highlighting the need for ongoing support in managing chronic conditions.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

A randomized trial of a theory-driven model of health coaching for older adults: short-term and sustained outcomes. Potempa, K., Calarco, M., Flaherty-Robb, M., et al.[2023]

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