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What is Novocain
ProcaineThe Generic name of this drug
Treatment SummaryProcaine is a type of anesthetic that is used to numb a specific area of the body. It is commonly used for injections to numb the skin, nerves or spine. It works quickly but its effects don’t last very long. It has also been studied as an oral medication to help treat HIV patients who have already tried other treatments.
Novocaineis the brand name
Novocain Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Novocaine
Procaine
2006
4
Approved as Treatment by the FDA
Procaine, commonly known as Novocaine, is approved by the FDA for 4 uses including Local Anesthetic Nerve Block and Regional Anesthetic Nerve Block .Local Anesthetic Nerve Block
Regional Anesthetic Nerve Block
Regional Analgesia
Local Analgesia
Effectiveness
How Novocain Affects PatientsProcaine is a type of anesthetic used to produce local or regional numbing, often used during oral surgery. Compared to other anesthetics like lidocaine, procaine has the additional benefit of reducing bleeding due to its ability to narrow blood vessels. It works by being broken down by the enzyme pseudocholinesterase in the blood. The resulting product is then passed through the kidneys and out of the body in the urine.
How Novocain works in the bodyProcaine works by stopping nerve signals from being sent. It does this by blocking sodium from entering the nerves, which prevents the signal from being sent. It also works to block certain receptors in the nerve cells that are used to send signals.
When to interrupt dosage
The quantity of Novocain is contingent upon the diagnosed disorder, including Cold Exposure, Regional Analgesia and Ischemic Stroke. The measure can be found in the table below, based on the administration procedure.Condition
Dosage
Administration
Low body temperature
, 2.0 %, 100.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL
, Infiltration, Liquid, Liquid - Infiltration, Solution, Solution - Infiltration, Injection, solution, Intraspinal; Intrathecal; Subarachnoid, Injection, solution - Intraspinal; Intrathecal; Subarachnoid, Injection, solution - Infiltration
Ischemic Stroke
, 2.0 %, 100.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL
, Infiltration, Liquid, Liquid - Infiltration, Solution, Solution - Infiltration, Injection, solution, Intraspinal; Intrathecal; Subarachnoid, Injection, solution - Intraspinal; Intrathecal; Subarachnoid, Injection, solution - Infiltration
Regional Anesthetic Nerve Block
, 2.0 %, 100.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL
, Infiltration, Liquid, Liquid - Infiltration, Solution, Solution - Infiltration, Injection, solution, Intraspinal; Intrathecal; Subarachnoid, Injection, solution - Intraspinal; Intrathecal; Subarachnoid, Injection, solution - Infiltration
Local Analgesia
, 2.0 %, 100.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL
, Infiltration, Liquid, Liquid - Infiltration, Solution, Solution - Infiltration, Injection, solution, Intraspinal; Intrathecal; Subarachnoid, Injection, solution - Intraspinal; Intrathecal; Subarachnoid, Injection, solution - Infiltration
Sudden Cardiac Arrest
, 2.0 %, 100.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL
, Infiltration, Liquid, Liquid - Infiltration, Solution, Solution - Infiltration, Injection, solution, Intraspinal; Intrathecal; Subarachnoid, Injection, solution - Intraspinal; Intrathecal; Subarachnoid, Injection, solution - Infiltration
Local Anesthetic Nerve Block
, 2.0 %, 100.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL
, Infiltration, Liquid, Liquid - Infiltration, Solution, Solution - Infiltration, Injection, solution, Intraspinal; Intrathecal; Subarachnoid, Injection, solution - Intraspinal; Intrathecal; Subarachnoid, Injection, solution - Infiltration
Open Heart Surgery
, 2.0 %, 100.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL
, Infiltration, Liquid, Liquid - Infiltration, Solution, Solution - Infiltration, Injection, solution, Intraspinal; Intrathecal; Subarachnoid, Injection, solution - Intraspinal; Intrathecal; Subarachnoid, Injection, solution - Infiltration
Regional Analgesia
, 2.0 %, 100.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL
, Infiltration, Liquid, Liquid - Infiltration, Solution, Solution - Infiltration, Injection, solution, Intraspinal; Intrathecal; Subarachnoid, Injection, solution - Intraspinal; Intrathecal; Subarachnoid, Injection, solution - Infiltration
otalgia
, 2.0 %, 100.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL
, Infiltration, Liquid, Liquid - Infiltration, Solution, Solution - Infiltration, Injection, solution, Intraspinal; Intrathecal; Subarachnoid, Injection, solution - Intraspinal; Intrathecal; Subarachnoid, Injection, solution - Infiltration
Warnings
Novocain ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Procaine may interact with Pulse Frequency
Common Novocain Drug Interactions
Drug Name
Risk Level
Description
2,5-Dimethoxy-4-ethylamphetamine
Major
Procaine may increase the hypertensive activities of 2,5-Dimethoxy-4-ethylamphetamine.
2,5-Dimethoxy-4-ethylthioamphetamine
Major
Procaine may increase the hypertensive activities of 2,5-Dimethoxy-4-ethylthioamphetamine.
4-Bromo-2,5-dimethoxyamphetamine
Major
Procaine may increase the hypertensive activities of 4-Bromo-2,5-dimethoxyamphetamine.
4-Methoxyamphetamine
Major
Procaine may increase the hypertensive activities of 4-Methoxyamphetamine.
5-methoxy-N,N-dimethyltryptamine
Major
The metabolism of 5-methoxy-N,N-dimethyltryptamine can be decreased when combined with Procaine.
Novocain Novel Uses: Which Conditions Have a Clinical Trial Featuring Novocain?
28 active studies are currently investigating the potential of Novocain to provide therapeutic relief for Heart attack, Regional Anesthetic Nerve Block and Otalgia.Condition
Clinical Trials
Trial Phases
Local Anesthetic Nerve Block
0 Actively Recruiting
Sudden Cardiac Arrest
10 Actively Recruiting
Not Applicable, Phase 2, Phase 3, Phase 1
otalgia
0 Actively Recruiting
Regional Analgesia
0 Actively Recruiting
Low body temperature
15 Actively Recruiting
Not Applicable, Phase 2, Early Phase 1, Phase 1
Regional Anesthetic Nerve Block
0 Actively Recruiting
Ischemic Stroke
1 Actively Recruiting
Not Applicable
Local Analgesia
0 Actively Recruiting
Open Heart Surgery
0 Actively Recruiting
Patient Q&A Section about novocain
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What does the drug Novocaine do?
"Novocaine is a local anesthetic drug. It numbs a specific part of the body, but does not make the person lose consciousness."
Answered by AI
Does Novocain make you loopy?
"Novocaine does not make you feel sleepy, however it does numb tissue. Many patients report feeling sluggish, as if they were tired or a little drunk. Novocaine can cause headaches, but usually not at the doses and locations used in dentistry."
Answered by AI
Is Novocain still used?
"Nowadays, Novocaine is not used as much because it takes too long to work and doesn't last very long. Lidocaine and Septocaine are better choices because they work more quickly and last longer. They also have a very small chance of causing allergic reactions."
Answered by AI
Does Novocain make you high?
"There is no potential for abuse with this anesthetic as it does not have any euphoric or addictive effects, though it can cause increased bleeding due to its ability to dilate blood vessels. A similar anesthetic compound is lidocaine, which was first synthesized in 1943."
Answered by AI