NOVOCART 3D for Articular Cartilage Injury
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial focuses on patients who did not respond to initial Microfracture treatment. The Microfracture procedure creates small holes in the bone to stimulate new cartilage growth, helping repair knee damage. Microfracture is a widely used technique for treating cartilage defects in the knee by creating small holes in the bone to stimulate new cartilage growth.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
How is the NOVOCART 3D treatment different from other treatments for articular cartilage injury?
NOVOCART 3D is unique because it is a matrix-based autologous chondrocyte implantation (ACI) that uses a biocompatible structure to support the growth of the patient's own cartilage cells, potentially reducing complications like graft hypertrophy (excessive tissue growth). This approach differs from traditional methods like microfracture, which involves creating small holes in the bone to stimulate cartilage growth, as it directly uses the patient's cells to repair the cartilage.12345
What data supports the effectiveness of the treatment NOVOCART 3D for articular cartilage injury?
Who Is on the Research Team?
Robert Spiro, PhD
Principal Investigator
Octane Biotherapeutics, Inc.
Are You a Good Fit for This Trial?
This trial is for people who were in a previous study (AAG-G-H-1220) and had an unsuccessful microfracture treatment on their knee. They must be willing to participate further and not have other health issues that could affect healing or the assessment of the treatment.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive the NOVOCART 3D matrix associated autologous chondrocyte implant
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- NOVOCART 3D
Find a Clinic Near You
Who Is Running the Clinical Trial?
Aesculap Biologics, LLC
Lead Sponsor