Nizoral

Histoplasmosis, Paracoccidioidomycosis, Chromoblastomycosis + 22 more
Treatment
8 Active Studies for Nizoral

What is Nizoral

KetoconazoleThe Generic name of this drug
Treatment SummarySalicylic acid is used for its anti-bacterial, anti-fungal, and skin-exfoliating properties. It is derived from the bark of the white willow tree and wintergreen leaves, but can also be synthesized in a lab. Salicylic acid is made into salts, called salicylates, which are used to ease pain.
Nizoralis the brand name
image of different drug pills on a surface
Nizoral Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Nizoral
Ketoconazole
1981
135

Effectiveness

How Nizoral Affects PatientsSalicylic acid is used to treat acne by helping dead skin cells fall off more easily, keeping pores from becoming clogged. It is also an ingredient in some shampoos that treat dandruff. People with darker skin may experience discoloration if salicylic acid is not used with a broad-spectrum sunscreen. Salicylic acid, in combination with bismuth, is also used in Pepto-Bismol, which helps with stomach discomfort, nausea, heartburn, and gas. It is also slightly antibacterial.
How Nizoral works in the bodySalicylic acid is used to help reduce inflammation and pain. It is also used in skin care products to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts. It helps skin cells slough off more easily, which is why it's used in dandruff shampoos. Salicylic acid also interferes with the production of certain molecules that are needed for wound healing.

When to interrupt dosage

The proposed dosage of Nizoral is contingent upon the identified affliction, including Dermatitis, corticosteroid-responsive dermatoses and Musculoskeletal Pain. The amount of dosage is dependent upon the method of delivery (e.g. Cream - Topical or Disc - Topical) outlined in the chart below.
Condition
Dosage
Administration
Histoplasmosis
, 0.02 mg/mg, 200.0 mg, 10.0 mg/mL, 20.0 mg, 20.0 mg/mL, 2.0 %, 20.5 mg/mL
, Topical, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Gel, Gel - Topical, Aerosol, foam, Aerosol, foam - Topical, Kit, Shampoo, Shampoo - Topical, Shampoo, suspension, Shampoo, suspension - Topical, Suspension - Oral, Suspension, Kit - Topical
Paracoccidioidomycosis
, 0.02 mg/mg, 200.0 mg, 10.0 mg/mL, 20.0 mg, 20.0 mg/mL, 2.0 %, 20.5 mg/mL
, Topical, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Gel, Gel - Topical, Aerosol, foam, Aerosol, foam - Topical, Kit, Shampoo, Shampoo - Topical, Shampoo, suspension, Shampoo, suspension - Topical, Suspension - Oral, Suspension, Kit - Topical
Chromoblastomycosis
, 0.02 mg/mg, 200.0 mg, 10.0 mg/mL, 20.0 mg, 20.0 mg/mL, 2.0 %, 20.5 mg/mL
, Topical, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Gel, Gel - Topical, Aerosol, foam, Aerosol, foam - Topical, Kit, Shampoo, Shampoo - Topical, Shampoo, suspension, Shampoo, suspension - Topical, Suspension - Oral, Suspension, Kit - Topical
Blastomycosis
, 0.02 mg/mg, 200.0 mg, 10.0 mg/mL, 20.0 mg, 20.0 mg/mL, 2.0 %, 20.5 mg/mL
, Topical, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Gel, Gel - Topical, Aerosol, foam, Aerosol, foam - Topical, Kit, Shampoo, Shampoo - Topical, Shampoo, suspension, Shampoo, suspension - Topical, Suspension - Oral, Suspension, Kit - Topical
Coccidioidomycosis
, 0.02 mg/mg, 200.0 mg, 10.0 mg/mL, 20.0 mg, 20.0 mg/mL, 2.0 %, 20.5 mg/mL
, Topical, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Gel, Gel - Topical, Aerosol, foam, Aerosol, foam - Topical, Kit, Shampoo, Shampoo - Topical, Shampoo, suspension, Shampoo, suspension - Topical, Suspension - Oral, Suspension, Kit - Topical
Dandruff
, 0.02 mg/mg, 200.0 mg, 10.0 mg/mL, 20.0 mg, 20.0 mg/mL, 2.0 %, 20.5 mg/mL
, Topical, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Gel, Gel - Topical, Aerosol, foam, Aerosol, foam - Topical, Kit, Shampoo, Shampoo - Topical, Shampoo, suspension, Shampoo, suspension - Topical, Suspension - Oral, Suspension, Kit - Topical
cutaneous candidiasis
, 0.02 mg/mg, 200.0 mg, 10.0 mg/mL, 20.0 mg, 20.0 mg/mL, 2.0 %, 20.5 mg/mL
, Topical, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Gel, Gel - Topical, Aerosol, foam, Aerosol, foam - Topical, Kit, Shampoo, Shampoo - Topical, Shampoo, suspension, Shampoo, suspension - Topical, Suspension - Oral, Suspension, Kit - Topical
Candidiasis, Vulvovaginal
, 0.02 mg/mg, 200.0 mg, 10.0 mg/mL, 20.0 mg, 20.0 mg/mL, 2.0 %, 20.5 mg/mL
, Topical, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Gel, Gel - Topical, Aerosol, foam, Aerosol, foam - Topical, Kit, Shampoo, Shampoo - Topical, Shampoo, suspension, Shampoo, suspension - Topical, Suspension - Oral, Suspension, Kit - Topical
Candidiasis, Chronic Mucocutaneous
, 0.02 mg/mg, 200.0 mg, 10.0 mg/mL, 20.0 mg, 20.0 mg/mL, 2.0 %, 20.5 mg/mL
, Topical, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Gel, Gel - Topical, Aerosol, foam, Aerosol, foam - Topical, Kit, Shampoo, Shampoo - Topical, Shampoo, suspension, Shampoo, suspension - Topical, Suspension - Oral, Suspension, Kit - Topical
Dermatitis, Seborrheic
, 0.02 mg/mg, 200.0 mg, 10.0 mg/mL, 20.0 mg, 20.0 mg/mL, 2.0 %, 20.5 mg/mL
, Topical, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Gel, Gel - Topical, Aerosol, foam, Aerosol, foam - Topical, Kit, Shampoo, Shampoo - Topical, Shampoo, suspension, Shampoo, suspension - Topical, Suspension - Oral, Suspension, Kit - Topical
Candidiasis, Vulvovaginal
, 0.02 mg/mg, 200.0 mg, 10.0 mg/mL, 20.0 mg, 20.0 mg/mL, 2.0 %, 20.5 mg/mL
, Topical, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Gel, Gel - Topical, Aerosol, foam, Aerosol, foam - Topical, Kit, Shampoo, Shampoo - Topical, Shampoo, suspension, Shampoo, suspension - Topical, Suspension - Oral, Suspension, Kit - Topical
Cushing Syndrome
, 0.02 mg/mg, 200.0 mg, 10.0 mg/mL, 20.0 mg, 20.0 mg/mL, 2.0 %, 20.5 mg/mL
, Topical, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Gel, Gel - Topical, Aerosol, foam, Aerosol, foam - Topical, Kit, Shampoo, Shampoo - Topical, Shampoo, suspension, Shampoo, suspension - Topical, Suspension - Oral, Suspension, Kit - Topical
Bacterial Vaginosis
, 0.02 mg/mg, 200.0 mg, 10.0 mg/mL, 20.0 mg, 20.0 mg/mL, 2.0 %, 20.5 mg/mL
, Topical, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Gel, Gel - Topical, Aerosol, foam, Aerosol, foam - Topical, Kit, Shampoo, Shampoo - Topical, Shampoo, suspension, Shampoo, suspension - Topical, Suspension - Oral, Suspension, Kit - Topical
Trichophyton mentagrophytes
, 0.02 mg/mg, 200.0 mg, 10.0 mg/mL, 20.0 mg, 20.0 mg/mL, 2.0 %, 20.5 mg/mL
, Topical, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Gel, Gel - Topical, Aerosol, foam, Aerosol, foam - Topical, Kit, Shampoo, Shampoo - Topical, Shampoo, suspension, Shampoo, suspension - Topical, Suspension - Oral, Suspension, Kit - Topical
Tinea cruris
, 0.02 mg/mg, 200.0 mg, 10.0 mg/mL, 20.0 mg, 20.0 mg/mL, 2.0 %, 20.5 mg/mL
, Topical, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Gel, Gel - Topical, Aerosol, foam, Aerosol, foam - Topical, Kit, Shampoo, Shampoo - Topical, Shampoo, suspension, Shampoo, suspension - Topical, Suspension - Oral, Suspension, Kit - Topical
Tinea Pedis
, 0.02 mg/mg, 200.0 mg, 10.0 mg/mL, 20.0 mg, 20.0 mg/mL, 2.0 %, 20.5 mg/mL
, Topical, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Gel, Gel - Topical, Aerosol, foam, Aerosol, foam - Topical, Kit, Shampoo, Shampoo - Topical, Shampoo, suspension, Shampoo, suspension - Topical, Suspension - Oral, Suspension, Kit - Topical
Tinea Pedis
, 0.02 mg/mg, 200.0 mg, 10.0 mg/mL, 20.0 mg, 20.0 mg/mL, 2.0 %, 20.5 mg/mL
, Topical, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Gel, Gel - Topical, Aerosol, foam, Aerosol, foam - Topical, Kit, Shampoo, Shampoo - Topical, Shampoo, suspension, Shampoo, suspension - Topical, Suspension - Oral, Suspension, Kit - Topical
Tinea corporis (disorder)
, 0.02 mg/mg, 200.0 mg, 10.0 mg/mL, 20.0 mg, 20.0 mg/mL, 2.0 %, 20.5 mg/mL
, Topical, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Gel, Gel - Topical, Aerosol, foam, Aerosol, foam - Topical, Kit, Shampoo, Shampoo - Topical, Shampoo, suspension, Shampoo, suspension - Topical, Suspension - Oral, Suspension, Kit - Topical
Tinea Pedis
, 0.02 mg/mg, 200.0 mg, 10.0 mg/mL, 20.0 mg, 20.0 mg/mL, 2.0 %, 20.5 mg/mL
, Topical, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Gel, Gel - Topical, Aerosol, foam, Aerosol, foam - Topical, Kit, Shampoo, Shampoo - Topical, Shampoo, suspension, Shampoo, suspension - Topical, Suspension - Oral, Suspension, Kit - Topical
recalcitrant Dermatophytosis
, 0.02 mg/mg, 200.0 mg, 10.0 mg/mL, 20.0 mg, 20.0 mg/mL, 2.0 %, 20.5 mg/mL
, Topical, Cream, Cream - Topical, Oral, Tablet, Tablet - Oral, Gel, Gel - Topical, Aerosol, foam, Aerosol, foam - Topical, Kit, Shampoo, Shampoo - Topical, Shampoo, suspension, Shampoo, suspension - Topical, Suspension - Oral, Suspension, Kit - Topical

Warnings

Nizoral Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Liver Dysfunction
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Long QT Syndrome
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Long QT Syndrome
Do Not Combine
Renal Insufficiency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
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Pulse Frequency
Do Not Combine
Pulse Frequency
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Pulse Frequency
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Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Ketoconazole may interact with Pulse Frequency
There are 20 known major drug interactions with Nizoral.
Common Nizoral Drug Interactions
Drug Name
Risk Level
Description
(R)-warfarin
Major
The metabolism of (R)-warfarin can be decreased when combined with Ketoconazole.
(S)-Warfarin
Major
The metabolism of (S)-Warfarin can be decreased when combined with Ketoconazole.
1,2-Benzodiazepine
Major
The metabolism of 1,2-Benzodiazepine can be decreased when combined with Ketoconazole.
3,5-diiodothyropropionic acid
Major
The metabolism of 3,5-diiodothyropropionic acid can be decreased when combined with Ketoconazole.
5-androstenedione
Major
The metabolism of 5-androstenedione can be decreased when combined with Ketoconazole.
Nizoral Toxicity & Overdose RiskThe lowest toxic dose of this drug for rats when taken orally is 891 mg/kg. When inhaled, the lowest toxic dose is greater than 900 mg/m3/1hr. Skin irritation in rabbits can be mild at 500 mg/24H and severe eye irritation has been reported with 100 mg. This drug has been investigated as a potential mutagen and has the capability to affect reproduction.
image of a doctor in a lab doing drug, clinical research

Nizoral Novel Uses: Which Conditions Have a Clinical Trial Featuring Nizoral?

81 active clinical trials are in progress to assess the potential of Nizoral to combat Palmoplantar Pustulosis (PPP), Communicable Diseases and Lichen Planus.
Condition
Clinical Trials
Trial Phases
Coccidioidomycosis
0 Actively Recruiting
Chromoblastomycosis
0 Actively Recruiting
Paracoccidioidomycosis
0 Actively Recruiting
Tinea corporis (disorder)
0 Actively Recruiting
Tinea corporis (disorder)
0 Actively Recruiting
Blastomycosis
0 Actively Recruiting
Candidiasis, Chronic Mucocutaneous
0 Actively Recruiting
Tinea Pedis
0 Actively Recruiting
Malassezia
0 Actively Recruiting
Candidiasis, Vulvovaginal
2 Actively Recruiting
Early Phase 1
recalcitrant Dermatophytosis
0 Actively Recruiting
Candidiasis, Systemic
0 Actively Recruiting
Trichophyton mentagrophytes
0 Actively Recruiting
Cushing Syndrome
0 Actively Recruiting
Tinea cruris
0 Actively Recruiting
Tinea Corporis caused by Trichophyton mentagrophytes
0 Actively Recruiting
Trichophyton rubrum
0 Actively Recruiting
cutaneous candidiasis
0 Actively Recruiting
Candidiasis, Vulvovaginal
0 Actively Recruiting
Bacterial Vaginosis
5 Actively Recruiting
Not Applicable, Phase 2, Early Phase 1, Phase 1

Nizoral Reviews: What are patients saying about Nizoral?

5Patient Review
3/16/2008
Nizoral for Ringworm of Scalp
This didn't do anything to help my child's ringworm. If anything, it made the problem worse.
5Patient Review
7/3/2012
Nizoral for Scaly Oily Skin Problem Primarily On Face and Scalp
Nizoral has been my go-to shampoo for fifteen years now. I've tried other options, but this one works the best by far for my scalp condition.
5Patient Review
8/10/2009
Nizoral for Fungal Infection of the Skin with Yellow Patches
This ointment has helped immensely with my seborrhea.
5Patient Review
2/19/2009
Nizoral for Fungal Infection of the Skin with Yellow Patches
I was patient and it finally paid off.
4Patient Review
5/24/2009
Nizoral for Scaly Oily Skin Problem Primarily On Face and Scalp
I usually get a fungus problem around my nose and face during winter, but this medication clears it up within three days. I've been using it on and off for ten years now.
View All Reviews
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Patient Q&A Section about nizoral

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What does Nizoral used for?

"Ketoconazole is used to treat various fungal infections of the skin such as athlete's foot, jock itch, ringworm, and dandruff. It can also treat a skin condition known as pityriasis (tinea versicolor), which is characterized by a lightening or darkening of the skin on the neck, chest, arms, or legs."

Answered by AI

Is it OK to use Nizoral shampoo everyday?

"How often should I use Nizoral?

You only need to use it every 3 to 4 days (twice a week) for 8 weeks. On the days you don't use Nizoral, you can use your regular shampoo and conditioner."

Answered by AI

How long does it take Nizoral to work?

"If you're using Nizoral to treat dandruff, you should start seeing results after the first wash. In most cases, dandruff will be gone within two weeks. If your scalp hasn't cleared up after four weeks, it's possible that you don't have dandruff and you should seek advice from a healthcare professional."

Answered by AI

What does Nizoral do to your hair?

"Ketoconazole, which is also known by the prescription name Nizoral, can help to decrease the production of testosterone. When testosterone is converted into a substance called DHT (dihydrotestosterone), it can destroy hair follicles and lead to hair loss."

Answered by AI

Clinical Trials for Nizoral

Have you considered Nizoral clinical trials? We made a collection of clinical trials featuring Nizoral, we think they might fit your search criteria.
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Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
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