Nerlynx

Breast Cancer
Treatment
2 FDA approvals
20 Active Studies for Nerlynx

What is Nerlynx

NeratinibThe Generic name of this drug
Treatment SummaryNeratinib is an extended adjuvant therapy used to treat Human Epidermal Growth Factor Receptor 2 (HER2) positive breast cancer. It was approved by the FDA in July 2017 and is sold under the brand name Nerlynx. Research is being conducted to see if Neratinib can be used to treat other forms of cancer.
Nerlynxis the brand name
image of different drug pills on a surface
Nerlynx Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Nerlynx
Neratinib
2017
1

Approved as Treatment by the FDA

Neratinib, also known as Nerlynx, is approved by the FDA for 2 uses like Breast Cancer and Breast Cancer .
Breast Cancer
Breast Cancer

Effectiveness

How Nerlynx Affects PatientsNeratinib is a medicine that acts against certain types of cancer caused by EGFR, HER2, and HER4. It works by blocking certain proteins in the body that can lead to cancer growth.
How Nerlynx works in the bodyNeratinib blocks cancer cells from sending signals to each other. It does this by stopping certain proteins from attaching to receptors on the cancer cells, which prevents those cells from receiving messages. This limits the cancer cells' ability to grow and spread.

When to interrupt dosage

The proposed measure of Nerlynx is contingent upon the manifested condition. The dose also changes as per the mode of delivery enumerated in the table beneath.
Condition
Dosage
Administration
Breast Cancer
, 40.0 mg
Oral, , Tablet - Oral, Tablet, Tablet, film coated - Oral, Tablet, film coated

Warnings

There are 20 known major drug interactions with Nerlynx.
Common Nerlynx Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The serum concentration of Abemaciclib can be increased when it is combined with Neratinib.
Axitinib
Major
The serum concentration of Axitinib can be increased when it is combined with Neratinib.
Bendamustine
Major
The serum concentration of Bendamustine can be increased when it is combined with Neratinib.
Binimetinib
Major
The serum concentration of Binimetinib can be increased when it is combined with Neratinib.
Bortezomib
Major
The serum concentration of Bortezomib can be increased when it is combined with Neratinib.
Nerlynx Toxicity & Overdose RiskTaking neratinib may cause diarrhea, liver damage, vomiting, dehydration, skin infection, kidney failure, nausea, tiredness, and abdominal pain. These side effects have been reported in clinical trials in patients taking neratinib.
image of a doctor in a lab doing drug, clinical research

Nerlynx Novel Uses: Which Conditions Have a Clinical Trial Featuring Nerlynx?

Presently, 677 active clinical trials are investigating the potential of Nerlynx to treat Breast Cancer.
Condition
Clinical Trials
Trial Phases
Breast Cancer
26 Actively Recruiting
Phase 2, Phase 1, Not Applicable

Nerlynx Reviews: What are patients saying about Nerlynx?

2.7Patient Review
6/2/2019
Nerlynx for HER2 Positive Breast Cancer
I had to limit my intake to four a day because it was really tough on my stomach. I don't have a gallbladder, and I suffer from bad acid reflux, so this drug was harder on me than my big chemo treatments. I took it for 10 months, but kept getting worse instead of better, with diarrhea. I've been off of it since May 1st of this year, and hopefully I'll start feeling better soon.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about nerlynx

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Nerlynx used for?

"NERYLNX is a prescription drug used to treat early-stage human epidermal growth factor receptor 2 (HER2)-positive breast cancer in adults who have previously been treated with a drug called trastuzumab."

Answered by AI

Is Nerlynx a chemo drug?

"Neratinib is a targeted therapy drug that is used to cancer cells. It attacks cancer cells by interfering with their ability to grow and divide."

Answered by AI

Is Nerlynx the same as Herceptin?

"Nerlynx is a drug that is approved by the FDA to treat early stage HER2-positive breast cancer. Nerlynx helps to prevent the cancer from returning in patients who have previously taken the drug trastuzumab. Nerlynx is used as an adjuvant therapy, which is a treatment that is used to prevent cancer from returning."

Answered by AI

How long do you take Nerlynx?

"If you're taking an acid reducer, you should take NERLYNX at least 2 hours before or 10 hours after. NERLYNX is usually taken for an entire year. If you miss a dose, just skip it and continue with your regular schedule."

Answered by AI

Clinical Trials for Nerlynx

Have you considered Nerlynx clinical trials? We made a collection of clinical trials featuring Nerlynx, we think they might fit your search criteria.
Have you considered Nerlynx clinical trials? We made a collection of clinical trials featuring Nerlynx, we think they might fit your search criteria.
Have you considered Nerlynx clinical trials? We made a collection of clinical trials featuring Nerlynx, we think they might fit your search criteria.
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Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
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