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Selective Cytopheretic Device for Acute Kidney Injury (NEUTRALIZE-AKI Trial)
NEUTRALIZE-AKI Trial Summary
This trial will test a device to see if it can improve survival and cut dialysis time for people with acute kidney injury in intensive care units.
NEUTRALIZE-AKI Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.NEUTRALIZE-AKI Trial Design
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Who is running the clinical trial?
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- I am currently hospitalized with COVID-19 as my main diagnosis.I have had an organ transplant.I haven't had a recent heart attack, stroke, or major blood vessel problem needing immediate treatment.My kidney function is normal or slightly reduced.I have been on continuous kidney replacement therapy for 12 to 48 hours.I have been in the ICU for more than 14 days during this hospital stay.I am in the ICU and need continuous kidney replacement therapy.I am on long-term dialysis for end-stage renal disease.I have a history of moderate to severe kidney disease.My advanced cancer is being treated, or may be treated, with palliative care.My veins are suitable for continuous kidney replacement therapy.I am on long-term medication to suppress my immune system.I am between 18 and 80 years old.I have another serious organ problem.I have a history of immune disorders like HIV/AIDS.I am currently receiving blood transfusions for active bleeding.My kidney injury is at least at stage 2 when starting treatment.I had a bone marrow transplant within the last year.I need a treatment to filter my blood during my hospital stay.My liver is failing despite having a long-term liver condition.I might have a condition affecting my liver and kidneys.
- Group 1: SCD + CKRT Arm
- Group 2: CKRT Alone Arm (standard of care)
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is there currently any room for individuals to join this trial?
"The latest updates on clinicaltrials.gov reveal that this trial, first posted in March of 2023, is not currently seeking new patients. Nevertheless, 823 other studies are actively recruiting participants at the moment."
Is enrollment in this research limited to individuals aged 25 or younger?
"As per this clinical trial's entrance prerequisites, participants must be aged between 18 and 80 years old."
How many medical institutions are currently conducting this research experiment?
"This trial currently operates from several sites, such as UCHealth University of Colorado Hospital in Aurora, Doctor's Hospital of Augusta in Augusta, and the University of Michigan in Ann Arbor. There are 11 other locations being utilized for this study."
Am I able to enroll in this experiment?
"This study is recruiting 200 participants with acute kidney injury, aged between 18 and 80 years old."
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