Nasalcrom

Urticaria Pigmentosa, Asthma, Keratoconjunctivitis + 9 more
Treatment
20 Active Studies for Nasalcrom

What is Nasalcrom

Cromoglicic acidThe Generic name of this drug
Treatment SummaryCromolyn is a medication used to prevent asthma attacks caused by allergies or exercise. It works by blocking the release of chemicals that cause inflammation in the lungs and airways. Cromolyn is not effective in treating an asthma attack already in progress.
Intalis the brand name
image of different drug pills on a surface
Nasalcrom Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Intal
Cromoglicic acid
1982
45

Effectiveness

How Nasalcrom Affects PatientsCromoglicate, or cromolyn, helps reduce bronchospasms (sudden constricting of the airways) triggered by allergens and is used to treat asthma and allergic rhinitis. It also comes as an eye drop to treat conjunctivitis, and can be taken by mouth to treat systemic mastocytosis and ulcerative colitis.
How Nasalcrom works in the bodyCromoglicate stops mast cells from releasing histamine and other substances that cause allergic reactions. It may do this by stopping calcium from entering the cells.

When to interrupt dosage

The endorsed dosage of Nasalcrom is contingent upon the diagnosed condition, such as Urticaria Pigmentosa, Exercise-Induced Bronchospasm and Conjunctivitis, Vernal. The measure of dosage can be found in the table below, depending on the technique of administration (e.g. Liquid; Spray or Respiratory (inhalation)).
Condition
Dosage
Administration
Urticaria Pigmentosa
, 20.0 mg/mL, 40.0 mg/mL, 100.0 mg/mL, 5.2 mg/mL, 20.0 mg, 2.0 %, 1.0 %, 100.0 mg, 1.0 mg, 5.2 mg, 1.0 mg/dose, 10.0 mg/mL, 0.04 mg/mg, 1.0 mg/pump actuation
, Oral, Liquid, Liquid - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intrabronchial, Solution, Solution - Intrabronchial, Solution, concentrate, Solution, concentrate - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Solution - Oral, Concentrate - Oral, Solution - Ophthalmic, Capsule - Oral, Capsule, Respiratory (inhalation), Solution - Respiratory (inhalation), Liquid - Ophthalmic, Liquid - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered; Solution, Aerosol, metered; Solution - Nasal, Aerosol, metered - Nasal, Powder, Powder - Respiratory (inhalation), Ointment, Ointment - Ophthalmic, Liquid; Spray, Liquid; Spray - Nasal, Spray, Spray - Nasal, Inhalant, Inhalant - Respiratory (inhalation)
Asthma
, 20.0 mg/mL, 40.0 mg/mL, 100.0 mg/mL, 5.2 mg/mL, 20.0 mg, 2.0 %, 1.0 %, 100.0 mg, 1.0 mg, 5.2 mg, 1.0 mg/dose, 10.0 mg/mL, 0.04 mg/mg, 1.0 mg/pump actuation
, Oral, Liquid, Liquid - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intrabronchial, Solution, Solution - Intrabronchial, Solution, concentrate, Solution, concentrate - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Solution - Oral, Concentrate - Oral, Solution - Ophthalmic, Capsule - Oral, Capsule, Respiratory (inhalation), Solution - Respiratory (inhalation), Liquid - Ophthalmic, Liquid - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered; Solution, Aerosol, metered; Solution - Nasal, Aerosol, metered - Nasal, Powder, Powder - Respiratory (inhalation), Ointment, Ointment - Ophthalmic, Liquid; Spray, Liquid; Spray - Nasal, Spray, Spray - Nasal, Inhalant, Inhalant - Respiratory (inhalation)
Keratoconjunctivitis
, 20.0 mg/mL, 40.0 mg/mL, 100.0 mg/mL, 5.2 mg/mL, 20.0 mg, 2.0 %, 1.0 %, 100.0 mg, 1.0 mg, 5.2 mg, 1.0 mg/dose, 10.0 mg/mL, 0.04 mg/mg, 1.0 mg/pump actuation
, Oral, Liquid, Liquid - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intrabronchial, Solution, Solution - Intrabronchial, Solution, concentrate, Solution, concentrate - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Solution - Oral, Concentrate - Oral, Solution - Ophthalmic, Capsule - Oral, Capsule, Respiratory (inhalation), Solution - Respiratory (inhalation), Liquid - Ophthalmic, Liquid - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered; Solution, Aerosol, metered; Solution - Nasal, Aerosol, metered - Nasal, Powder, Powder - Respiratory (inhalation), Ointment, Ointment - Ophthalmic, Liquid; Spray, Liquid; Spray - Nasal, Spray, Spray - Nasal, Inhalant, Inhalant - Respiratory (inhalation)
Bronchospasm, Exercise-Induced
, 20.0 mg/mL, 40.0 mg/mL, 100.0 mg/mL, 5.2 mg/mL, 20.0 mg, 2.0 %, 1.0 %, 100.0 mg, 1.0 mg, 5.2 mg, 1.0 mg/dose, 10.0 mg/mL, 0.04 mg/mg, 1.0 mg/pump actuation
, Oral, Liquid, Liquid - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intrabronchial, Solution, Solution - Intrabronchial, Solution, concentrate, Solution, concentrate - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Solution - Oral, Concentrate - Oral, Solution - Ophthalmic, Capsule - Oral, Capsule, Respiratory (inhalation), Solution - Respiratory (inhalation), Liquid - Ophthalmic, Liquid - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered; Solution, Aerosol, metered; Solution - Nasal, Aerosol, metered - Nasal, Powder, Powder - Respiratory (inhalation), Ointment, Ointment - Ophthalmic, Liquid; Spray, Liquid; Spray - Nasal, Spray, Spray - Nasal, Inhalant, Inhalant - Respiratory (inhalation)
Conjunctivitis, Allergic
, 20.0 mg/mL, 40.0 mg/mL, 100.0 mg/mL, 5.2 mg/mL, 20.0 mg, 2.0 %, 1.0 %, 100.0 mg, 1.0 mg, 5.2 mg, 1.0 mg/dose, 10.0 mg/mL, 0.04 mg/mg, 1.0 mg/pump actuation
, Oral, Liquid, Liquid - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intrabronchial, Solution, Solution - Intrabronchial, Solution, concentrate, Solution, concentrate - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Solution - Oral, Concentrate - Oral, Solution - Ophthalmic, Capsule - Oral, Capsule, Respiratory (inhalation), Solution - Respiratory (inhalation), Liquid - Ophthalmic, Liquid - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered; Solution, Aerosol, metered; Solution - Nasal, Aerosol, metered - Nasal, Powder, Powder - Respiratory (inhalation), Ointment, Ointment - Ophthalmic, Liquid; Spray, Liquid; Spray - Nasal, Spray, Spray - Nasal, Inhalant, Inhalant - Respiratory (inhalation)
Hay Fever
, 20.0 mg/mL, 40.0 mg/mL, 100.0 mg/mL, 5.2 mg/mL, 20.0 mg, 2.0 %, 1.0 %, 100.0 mg, 1.0 mg, 5.2 mg, 1.0 mg/dose, 10.0 mg/mL, 0.04 mg/mg, 1.0 mg/pump actuation
, Oral, Liquid, Liquid - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intrabronchial, Solution, Solution - Intrabronchial, Solution, concentrate, Solution, concentrate - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Solution - Oral, Concentrate - Oral, Solution - Ophthalmic, Capsule - Oral, Capsule, Respiratory (inhalation), Solution - Respiratory (inhalation), Liquid - Ophthalmic, Liquid - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered; Solution, Aerosol, metered; Solution - Nasal, Aerosol, metered - Nasal, Powder, Powder - Respiratory (inhalation), Ointment, Ointment - Ophthalmic, Liquid; Spray, Liquid; Spray - Nasal, Spray, Spray - Nasal, Inhalant, Inhalant - Respiratory (inhalation)
Seasonal Allergic Conjunctivitis
, 20.0 mg/mL, 40.0 mg/mL, 100.0 mg/mL, 5.2 mg/mL, 20.0 mg, 2.0 %, 1.0 %, 100.0 mg, 1.0 mg, 5.2 mg, 1.0 mg/dose, 10.0 mg/mL, 0.04 mg/mg, 1.0 mg/pump actuation
, Oral, Liquid, Liquid - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intrabronchial, Solution, Solution - Intrabronchial, Solution, concentrate, Solution, concentrate - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Solution - Oral, Concentrate - Oral, Solution - Ophthalmic, Capsule - Oral, Capsule, Respiratory (inhalation), Solution - Respiratory (inhalation), Liquid - Ophthalmic, Liquid - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered; Solution, Aerosol, metered; Solution - Nasal, Aerosol, metered - Nasal, Powder, Powder - Respiratory (inhalation), Ointment, Ointment - Ophthalmic, Liquid; Spray, Liquid; Spray - Nasal, Spray, Spray - Nasal, Inhalant, Inhalant - Respiratory (inhalation)
Asthma, Exercise-Induced
, 20.0 mg/mL, 40.0 mg/mL, 100.0 mg/mL, 5.2 mg/mL, 20.0 mg, 2.0 %, 1.0 %, 100.0 mg, 1.0 mg, 5.2 mg, 1.0 mg/dose, 10.0 mg/mL, 0.04 mg/mg, 1.0 mg/pump actuation
, Oral, Liquid, Liquid - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intrabronchial, Solution, Solution - Intrabronchial, Solution, concentrate, Solution, concentrate - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Solution - Oral, Concentrate - Oral, Solution - Ophthalmic, Capsule - Oral, Capsule, Respiratory (inhalation), Solution - Respiratory (inhalation), Liquid - Ophthalmic, Liquid - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered; Solution, Aerosol, metered; Solution - Nasal, Aerosol, metered - Nasal, Powder, Powder - Respiratory (inhalation), Ointment, Ointment - Ophthalmic, Liquid; Spray, Liquid; Spray - Nasal, Spray, Spray - Nasal, Inhalant, Inhalant - Respiratory (inhalation)
Conjunctivitis, Allergic
, 20.0 mg/mL, 40.0 mg/mL, 100.0 mg/mL, 5.2 mg/mL, 20.0 mg, 2.0 %, 1.0 %, 100.0 mg, 1.0 mg, 5.2 mg, 1.0 mg/dose, 10.0 mg/mL, 0.04 mg/mg, 1.0 mg/pump actuation
, Oral, Liquid, Liquid - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intrabronchial, Solution, Solution - Intrabronchial, Solution, concentrate, Solution, concentrate - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Solution - Oral, Concentrate - Oral, Solution - Ophthalmic, Capsule - Oral, Capsule, Respiratory (inhalation), Solution - Respiratory (inhalation), Liquid - Ophthalmic, Liquid - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered; Solution, Aerosol, metered; Solution - Nasal, Aerosol, metered - Nasal, Powder, Powder - Respiratory (inhalation), Ointment, Ointment - Ophthalmic, Liquid; Spray, Liquid; Spray - Nasal, Spray, Spray - Nasal, Inhalant, Inhalant - Respiratory (inhalation)
Rhinitis, Allergic
, 20.0 mg/mL, 40.0 mg/mL, 100.0 mg/mL, 5.2 mg/mL, 20.0 mg, 2.0 %, 1.0 %, 100.0 mg, 1.0 mg, 5.2 mg, 1.0 mg/dose, 10.0 mg/mL, 0.04 mg/mg, 1.0 mg/pump actuation
, Oral, Liquid, Liquid - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intrabronchial, Solution, Solution - Intrabronchial, Solution, concentrate, Solution, concentrate - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Solution - Oral, Concentrate - Oral, Solution - Ophthalmic, Capsule - Oral, Capsule, Respiratory (inhalation), Solution - Respiratory (inhalation), Liquid - Ophthalmic, Liquid - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered; Solution, Aerosol, metered; Solution - Nasal, Aerosol, metered - Nasal, Powder, Powder - Respiratory (inhalation), Ointment, Ointment - Ophthalmic, Liquid; Spray, Liquid; Spray - Nasal, Spray, Spray - Nasal, Inhalant, Inhalant - Respiratory (inhalation)
Hypersensitivity
, 20.0 mg/mL, 40.0 mg/mL, 100.0 mg/mL, 5.2 mg/mL, 20.0 mg, 2.0 %, 1.0 %, 100.0 mg, 1.0 mg, 5.2 mg, 1.0 mg/dose, 10.0 mg/mL, 0.04 mg/mg, 1.0 mg/pump actuation
, Oral, Liquid, Liquid - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intrabronchial, Solution, Solution - Intrabronchial, Solution, concentrate, Solution, concentrate - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Solution - Oral, Concentrate - Oral, Solution - Ophthalmic, Capsule - Oral, Capsule, Respiratory (inhalation), Solution - Respiratory (inhalation), Liquid - Ophthalmic, Liquid - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered; Solution, Aerosol, metered; Solution - Nasal, Aerosol, metered - Nasal, Powder, Powder - Respiratory (inhalation), Ointment, Ointment - Ophthalmic, Liquid; Spray, Liquid; Spray - Nasal, Spray, Spray - Nasal, Inhalant, Inhalant - Respiratory (inhalation)
Food Hypersensitivity
, 20.0 mg/mL, 40.0 mg/mL, 100.0 mg/mL, 5.2 mg/mL, 20.0 mg, 2.0 %, 1.0 %, 100.0 mg, 1.0 mg, 5.2 mg, 1.0 mg/dose, 10.0 mg/mL, 0.04 mg/mg, 1.0 mg/pump actuation
, Oral, Liquid, Liquid - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intrabronchial, Solution, Solution - Intrabronchial, Solution, concentrate, Solution, concentrate - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Solution - Oral, Concentrate - Oral, Solution - Ophthalmic, Capsule - Oral, Capsule, Respiratory (inhalation), Solution - Respiratory (inhalation), Liquid - Ophthalmic, Liquid - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered; Solution, Aerosol, metered; Solution - Nasal, Aerosol, metered - Nasal, Powder, Powder - Respiratory (inhalation), Ointment, Ointment - Ophthalmic, Liquid; Spray, Liquid; Spray - Nasal, Spray, Spray - Nasal, Inhalant, Inhalant - Respiratory (inhalation)

Warnings

There are 1 known major drug interactions with Nasalcrom.
Common Nasalcrom Drug Interactions
Drug Name
Risk Level
Description
Methacholine
Minor
Cromoglicic acid may decrease effectiveness of Methacholine as a diagnostic agent.
Nasalcrom Toxicity & Overdose RiskOverdosing on Claritin can cause coughing, stuffiness, vomiting, sneezing and difficulty breathing.
image of a doctor in a lab doing drug, clinical research

Nasalcrom Novel Uses: Which Conditions Have a Clinical Trial Featuring Nasalcrom?

157 active clinical trials are currently examining the capacity of Nasalcrom to address Asthma, Vernal Keratoconjunctivitis and Seasonal Allergic Conjunctivitis.
Condition
Clinical Trials
Trial Phases
Asthma
92 Actively Recruiting
Phase 1, Phase 4, Early Phase 1, Phase 2, Not Applicable, Phase 3
Conjunctivitis, Allergic
1 Actively Recruiting
Phase 2
Keratoconjunctivitis
0 Actively Recruiting
Rhinitis, Allergic
0 Actively Recruiting
Food Hypersensitivity
0 Actively Recruiting
Hypersensitivity
0 Actively Recruiting
Urticaria Pigmentosa
0 Actively Recruiting
Bronchospasm, Exercise-Induced
0 Actively Recruiting
Seasonal Allergic Conjunctivitis
0 Actively Recruiting
Conjunctivitis, Allergic
0 Actively Recruiting
Hay Fever
0 Actively Recruiting
Asthma, Exercise-Induced
0 Actively Recruiting

Nasalcrom Reviews: What are patients saying about Nasalcrom?

5Patient Review
5/9/2012
Nasalcrom for Inflammation of the Nose due to an Allergy
I cannot sing the praises of this product enough. I have never found anything that is as effective at managing my allergies with NO side effects.
5Patient Review
9/29/2014
Nasalcrom for Inflammation of the Nose due to an Allergy
Nasalcrom is really the best allergy medication, by far. It's a shame that doctors don't seem to prescribe it more often because other drugs companies are paying them to push their own products.
5Patient Review
6/12/2014
Nasalcrom for Inflammation of the Nose due to an Allergy
I used to have to get weekly allergy injections for years, but they eventually stopped being effective. I've tried a lot of different treatments since then, and Nasalcrom is by far the best. It's non-habit forming and doesn't cause rebound congestion, which are both big pluses in my book.
5Patient Review
3/2/2017
Nasalcrom for Inflammation of the Nose due to an Allergy
I'm so baffled that this isn't the go-to treatment for allergies. It worked great for me with zero side effects, and I know plenty of other people who say the same. If you're struggling with allergies, please give this a try before trying anything else.
5Patient Review
11/20/2015
Nasalcrom for Inflammation of the Nose due to an Allergy
I've been using Nasalcrom for years, and it's really helped me with my asthma and allergies. I'm surprised at how well it works, and it also seems to help protect me from getting colds.
5Patient Review
3/29/2017
Nasalcrom for Inflammation of the Nose due to an Allergy
This is an absolute game-changer for me. I've suffered from pollen allergies and acid reflux for fifteen years, and NasalCrom has completely alleviated both problems in just three days. I feel like a new person!
5Patient Review
7/21/2018
Nasalcrom for Inflammation of the Nose due to an Allergy
I've had great results using Nasalcrom to clear up mild stuffiness. It's perfect for me because I don't have major allergy problems, but it helps during high allergy seasons in the spring and fall.
5Patient Review
11/11/2012
Nasalcrom for Inflammation of the Nose due to an Allergy
I've had a lifetime of nasal polyps, and this product has really helped to keep them at bay. It's been 11 years now that I've used it twice daily, spraying each nostril once, and my doctor says the Nasalcrom has prevented the polyps from growing any larger.
5Patient Review
12/4/2018
Nasalcrom for Inflammation of the Nose due to an Allergy
I've been told that this medication didn't work for other people, but it's the only thing that works for me with normal allergy issues. My doctor said that if it worked, I should keep using it. He was unaware of any side effects. I do know that I need to take it before I get an infection in the early stages of allergy issues.
5Patient Review
4/11/2013
Nasalcrom for Inflammation of the Nose due to an Allergy
I tried this product a few years ago and loved it. I was thrilled to find that it's still available today. This is by far the best allergy medication I've ever used.
5Patient Review
8/13/2017
Nasalcrom for Inflammation of the Nose due to an Allergy
I have allergies year-round, and this medication was the only one that helped me without any sort of drowsy or awake side effects. I highly recommend it to anyone who suffers from allergies like I do!
4.3Patient Review
1/8/2014
Nasalcrom for Inflammation of the Nose due to an Allergy
Flonase worked well for me, but it had a lot of side effects. Nasalcrom is just as effective, but without any negative consequences. The only downside is that I have to use it more frequently than I'd like.
4Patient Review
11/5/2014
Nasalcrom for Inflammation of the Nose due to an Allergy
I've been using this medication for a few months now and it's helped me a lot. However, I'm starting to experience allergies again. Not sure if there are certain allergens this medication doesn't help with or what the deal is.
3.7Patient Review
9/15/2013
Nasalcrom for Inflammation of the Nose due to an Allergy
Patanase was much more effective, but at $175 a bottle it's not feasible for me to keep using it. My doctor recommended trying nasalcrom instead to see if it would be as effective; unfortunately, it takes longer to help but is only $14.99.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about nasalcrom

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who should not use nasalcrom?

"If you are pregnant, breastfeeding, have asthma, liver or kidney disease, or are giving this medicine to a child under 6 years of age, talk to your doctor before using Nasalcrom."

Answered by AI

Is nasalcrom a steroid?

"NasalCrom helps to reduce allergy symptoms by blocking histamines. It is not a corticosteroid."

Answered by AI

Is nasalcrom an antihistamine?

"It provides relief from the symptoms of seasonal allergies and other allergies, including a stuffy or runny nose, mucus dripping into the back of the throat, itching, and sneezing. This medication does not work immediately, but it is not an antihistamine."

Answered by AI

Does nasalcrom have any side effects?

"If you experience any severe burning, stinging, or irritation in your nose while using Nasalcrom, stop using the product immediately and consult a doctor. Additionally, keep an eye out for nosebleeds, sinus pain, or sores in your nose, as well as wheezing, tightness in your chest, or fever as these may also be signs of a reaction. Finally, it's not uncommon for Nasalcrom to cause a runny nose with green or yellow mucus."

Answered by AI

Clinical Trials for Nasalcrom

Have you considered Nasalcrom clinical trials? We made a collection of clinical trials featuring Nasalcrom, we think they might fit your search criteria.Go to Trials
Image of Allergy Immunology Associates in Mayfield Heights, United States.

Osteopathic Manipulative Treatment for Asthma

18 - 60
All Sexes
Mayfield Heights, OH
Asthma is a common respiratory condition that can be difficult to control despite the use of medications such as inhalers, oral steroids or even injectable medications. Osteopathic Manipulative Treatment (OMT) is a hands-on technique used to improve the chest structure and function and may help in improving breathing. Previous research showed that OMT in asthma patients, can improve the movement of the ribs and improve the "peak flow" which is the maximum rate at which a person can exhale air after taking a deep breath. However, no studies have evaluated the impact of OMT on lung inflammation. This single-site research study at University Hospitals aims to evaluate whether Osteopathic Manipulative Treatment (OMT) can reduce lung inflammation and improve breathing and lung function in adult patients with asthma. The lung function will be evaluated by Spirometry which is a test that measures how much air you can breathe in and out of your lungs, as well as how quickly and easily you can exhale air. The lung inflammation will be measured using a device that can detect how much you are breathing out Nitric Oxide which is a gas produced by inflamed cells in the lungs, this test is called: Fractional exhaled Nitric Oxide or FeNO. Approximately 100 participants will be enrolled.
Waitlist Available
Has No Placebo
Allergy Immunology AssociatesNancy Wasserbauer-Kingston, DO
Image of DARTNet Institute in Aurora, United States.

Inhaled Corticosteroids + Azithromycin for Asthma

13 - 75
All Sexes
Aurora, CO
While asthma therapy is becoming more individualized based on asthma phenotypes, more research is needed to tailor newer therapies to individuals. Inhaled corticosteroid (ICS) medications are the foundation of care for all individuals with persistent asthma. But ICS use is not without possible long term side effects. This study will compare two currently available approaches to reduce AEX in primary care patients: (1) use of inhaled corticosteroids (ICS) as part of rescue therapy, also known as MART (Maintenance And Reliever Therapy) or PARTICS (Patient Activated Reliever Trigger Inhaled Corticosteriods) therapy - either of these therapies will be called Rescue-Inhaled Corticosteroids or R-ICS pronounced "Ricks," and (2) use of azithromycin (AZ) as a preventive therapy. These treatments will be studied both individually and in combination.
Phase 4
Recruiting
DARTNet Institute (+12 Sites)Wilson D Pace, MD, FAAFP
Image of Medical Place Pharmacy in Ajax, Canada.

Pharmacy Support System for Asthma

Any Age
All Sexes
Ajax, Canada
The goal of this study is to assess the effect of an electronic asthma management system in pharmacies (eAMS-Pharm) on asthma control assessment, asthma medication adjustment, asthma action plan delivery, and prompting for specialist referral in severe asthma. The study assesses the differences on pharmacy processes (affecting both the pharmacy team and patients) and pharmacy-delivered care using an interrupted time-series analysis (six-months before vs. six-months after the introduction of eAMS-Pharm in study pharmacy sites). The eAMS-Pharm uses patient data (asthma control, asthma flare-up risk, and current medications) to provide clinical decision support to pharmacists, empowering them to bridge existing gaps between guideline-recommended asthma care and patient care received.
Waitlist Available
Has No Placebo
Medical Place Pharmacy (+2 Sites)
Have you considered Nasalcrom clinical trials? We made a collection of clinical trials featuring Nasalcrom, we think they might fit your search criteria.Go to Trials
Image of Velocity Clinical Research, Mobile in Mobile, United States.

PF-07275315 for Asthma

18 - 70
All Sexes
Mobile, AL
The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called PF-07275315) for the potential treatment of moderate-to-severe asthma. Asthma is a condition that makes it challenging to breathe, which negatively impacts the quality of life and functioning of people who are affected. This study is seeking participants who: * Are 18 to 70 years old * Have had moderate-to-severe asthma for at least 12 months that is not well controlled * Have been taking their regular maintenance treatment(s) for asthma over the last 12 months All participants will receive PF-07275315 or a placebo. A placebo does not have any medicine in it but looks just like the medicine being studied. PF-07275315 or placebo will be given as multiple shots in the clinic over the course of 12 weeks. We will compare the experiences of people receiving PF-07275315 to those of the people who do not. This will help us determine if PF-07275315 is safe and effective. Participants will be involved in this study for about 9.5 months. During this time, they will have 10 visits at the study clinic.
Phase 2
Recruiting
Velocity Clinical Research, Mobile (+10 Sites)Pfizer CT.gov Call CenterPfizer
Image of St. Joseph's Healthcare Hamilton in Hamilton, Canada.

Corticosteroids for Asthma

18+
All Sexes
Hamilton, Canada
Most individuals with asthma can effectively manage their symptoms and maintain normal lung function using inhaled medications, unfortunately, there is a subset of asthma sufferers whose symptoms, lung function, and risk of asthma attacks remain unimproved despite conventional inhaled medications. There could be several reasons for this. One possibility is that inhaled medications fail to reach the intended areas within the lungs, due to structural abnormalities within the airways themselves. Much like road conditions or closures can impede the speed and efficiency of vehicle travel, factors such as airway narrowing or mucus blockages, which are common in asthma, can obstruct the passage of inhaled medications through the airways. Our team has now optimized advanced medical imaging techniques, including magnetic resonance imaging (MRI) and computed tomography (CT), required to investigate this. This study will use these imaging methods to visually assess and measure individual patients' airways and determine whether abnormal airway structures impact how well they respond to inhaled and orally delivered medications. We anticipate finding that abnormal airway structures make inhaled medications less effective, but that they do not affect the response to oral medications.
Phase 4
Recruiting
St. Joseph's Healthcare Hamilton (+1 Sites)
Have you considered Nasalcrom clinical trials? We made a collection of clinical trials featuring Nasalcrom, we think they might fit your search criteria.Go to Trials
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