Metrogel

Pouchitis, Liver Abscess, Amebic, Lung Abscess + 53 more

Treatment

41 FDA approvals

20 Active Studies for Metrogel

What is Metrogel

Metronidazole

The Generic name of this drug

Treatment Summary

Metronidazole is an antibiotic used to treat many different types of bacterial and parasitic infections. It has been used for decades to treat gastrointestinal problems and trichomoniasis, giardiasis, and amebiasis. It is available in capsule, tablet, topical, and suppository forms. Metronidazole is a powerful antibiotic that helps fight off infections that many other antibiotics cannot treat.

Flagyl

is the brand name

image of different drug pills on a surface

Metrogel Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Flagyl

Metronidazole

1963

449

Approved as Treatment by the FDA

Metronidazole, commonly known as Flagyl, is approved by the FDA for 41 uses including Abscess and Bone and Joint Infections .

Abscess

Bone and Joint Infections

Liver Abscess

Communicable Diseases

Osteomyelitis

Bacterial Endocarditis

Helicobacter Pylori Infection

Used to treat Helicobacter Pylori Infection in combination with Bismuth subsalicylate

Abdominal Abscess

Abdominal Infection

Skin and skin structure infections

Gynaecological infection

Lung Abscess

Endometritis

Central Nervous System Bacterial Infections

Bacterial Meningitis

Pneumonia

intra-abdominal bacterial infections

hepatic abscess

Tubo-ovarian abscess

Lung Abscess

Curling Ulcer

Used to treat Duodenal Ulcer in combination with Bismuth subsalicylate

Lower respiratory tract infection bacterial

Bacterial Septicemia

Bacteria, Anaerobic

Bacterial Infections

Duodenal Ulcer

Used to treat Duodenal Ulcer in combination with Bismuth subsalicylate

Meningitis

Abscess, Intra-Abdominal

Empyema

asymptomatic Trichomoniasis

Exposure via partner

Endomyometritis

Bacterial Peritonitis

Central Nervous System Bacterial Infections

Empyema

Trichomonas Infections

Endometritis

Endometritis

Bacteria

Endocarditis, Bacterial

Communicable Diseases

Effectiveness

How Metrogel Affects Patients

Metronidazole is a medication used to treat certain infections caused by bacteria and parasites. It works by attacking the DNA of the bacteria or parasites, killing them. It is important to be aware of the risk of nerve damage and convulsions associated with metronidazole, so it should only be taken when it is necessary and for its approved indications. Animal studies have suggested that metronidazole may cause cancer, but it is unknown if this would apply to people.

How Metrogel works in the body

Metronidazole works by attacking the DNA and electron-transport proteins of anaerobic bacteria and protozoa. It enters these cells, then is reduced to nitro radicals. This reduction process is only done by anaerobic or microaerophilic organisms, so metronidazole is selective to these. The result of this reduction is toxic metabolites, which damage the replicating organisms' DNA.

When to interrupt dosage

The prescribed dosage of Metrogel is contingent upon the determined illness, including Exposure via partner, Skin and Curling Ulcer. The amount likewise changes as per the technique of conveyance (e.g. Capsule or Vaginal) specified in the table beneath.

Condition

Dosage

Administration

Bacterial Vaginosis

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution, Solution - Intravenous, Capsule, Capsule - Oral, Vaginal, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, film coated - Oral, Tablet, film coated, Gel - Vaginal, Tablet, film coated, extended release, Ointment - Topical, Insert - Vaginal, Insert, Kit, Tablet, extended release - Oral, Tablet, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated, Tablet, coated - Oral, Injection - Intravenous, Kit - Oral, Ointment

Exposure via partner

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution, Solution - Intravenous, Capsule, Capsule - Oral, Vaginal, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, film coated - Oral, Tablet, film coated, Gel - Vaginal, Tablet, film coated, extended release, Ointment - Topical, Insert - Vaginal, Insert, Kit, Tablet, extended release - Oral, Tablet, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated, Tablet, coated - Oral, Injection - Intravenous, Kit - Oral, Ointment

Tubo-ovarian abscess

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution, Solution - Intravenous, Capsule, Capsule - Oral, Vaginal, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, film coated - Oral, Tablet, film coated, Gel - Vaginal, Tablet, film coated, extended release, Ointment - Topical, Insert - Vaginal, Insert, Kit, Tablet, extended release - Oral, Tablet, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated, Tablet, coated - Oral, Injection - Intravenous, Kit - Oral, Ointment

Bacterial Septicemia

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution, Solution - Intravenous, Capsule, Capsule - Oral, Vaginal, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, film coated - Oral, Tablet, film coated, Gel - Vaginal, Tablet, film coated, extended release, Ointment - Topical, Insert - Vaginal, Insert, Kit, Tablet, extended release - Oral, Tablet, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated, Tablet, coated - Oral, Injection - Intravenous, Kit - Oral, Ointment

Vaginitis

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution, Solution - Intravenous, Capsule, Capsule - Oral, Vaginal, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, film coated - Oral, Tablet, film coated, Gel - Vaginal, Tablet, film coated, extended release, Ointment - Topical, Insert - Vaginal, Insert, Kit, Tablet, extended release - Oral, Tablet, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated, Tablet, coated - Oral, Injection - Intravenous, Kit - Oral, Ointment

Bacterial Peritonitis

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution, Solution - Intravenous, Capsule, Capsule - Oral, Vaginal, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, film coated - Oral, Tablet, film coated, Gel - Vaginal, Tablet, film coated, extended release, Ointment - Topical, Insert - Vaginal, Insert, Kit, Tablet, extended release - Oral, Tablet, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated, Tablet, coated - Oral, Injection - Intravenous, Kit - Oral, Ointment

Trichomonas Vaginitis

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution, Solution - Intravenous, Capsule, Capsule - Oral, Vaginal, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, film coated - Oral, Tablet, film coated, Gel - Vaginal, Tablet, film coated, extended release, Ointment - Topical, Insert - Vaginal, Insert, Kit, Tablet, extended release - Oral, Tablet, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated, Tablet, coated - Oral, Injection - Intravenous, Kit - Oral, Ointment

post-surgical vaginal cuff infection

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution, Solution - Intravenous, Capsule, Capsule - Oral, Vaginal, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, film coated - Oral, Tablet, film coated, Gel - Vaginal, Tablet, film coated, extended release, Ointment - Topical, Insert - Vaginal, Insert, Kit, Tablet, extended release - Oral, Tablet, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated, Tablet, coated - Oral, Injection - Intravenous, Kit - Oral, Ointment

Inflammatory Papule

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution, Solution - Intravenous, Capsule, Capsule - Oral, Vaginal, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, film coated - Oral, Tablet, film coated, Gel - Vaginal, Tablet, film coated, extended release, Ointment - Topical, Insert - Vaginal, Insert, Kit, Tablet, extended release - Oral, Tablet, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated, Tablet, coated - Oral, Injection - Intravenous, Kit - Oral, Ointment

Pouchitis

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution, Solution - Intravenous, Capsule, Capsule - Oral, Vaginal, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, film coated - Oral, Tablet, film coated, Gel - Vaginal, Tablet, film coated, extended release, Ointment - Topical, Insert - Vaginal, Insert, Kit, Tablet, extended release - Oral, Tablet, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated, Tablet, coated - Oral, Injection - Intravenous, Kit - Oral, Ointment

Giardiasis

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution, Solution - Intravenous, Capsule, Capsule - Oral, Vaginal, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, film coated - Oral, Tablet, film coated, Gel - Vaginal, Tablet, film coated, extended release, Ointment - Topical, Insert - Vaginal, Insert, Kit, Tablet, extended release - Oral, Tablet, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated, Tablet, coated - Oral, Injection - Intravenous, Kit - Oral, Ointment

Vulvovaginitis

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution, Solution - Intravenous, Capsule, Capsule - Oral, Vaginal, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, film coated - Oral, Tablet, film coated, Gel - Vaginal, Tablet, film coated, extended release, Ointment - Topical, Insert - Vaginal, Insert, Kit, Tablet, extended release - Oral, Tablet, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated, Tablet, coated - Oral, Injection - Intravenous, Kit - Oral, Ointment

Uterine Cervicitis

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution, Solution - Intravenous, Capsule, Capsule - Oral, Vaginal, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, film coated - Oral, Tablet, film coated, Gel - Vaginal, Tablet, film coated, extended release, Ointment - Topical, Insert - Vaginal, Insert, Kit, Tablet, extended release - Oral, Tablet, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated, Tablet, coated - Oral, Injection - Intravenous, Kit - Oral, Ointment

Communicable Diseases

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution, Solution - Intravenous, Capsule, Capsule - Oral, Vaginal, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, film coated - Oral, Tablet, film coated, Gel - Vaginal, Tablet, film coated, extended release, Ointment - Topical, Insert - Vaginal, Insert, Kit, Tablet, extended release - Oral, Tablet, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated, Tablet, coated - Oral, Injection - Intravenous, Kit - Oral, Ointment

Candida albicans

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution, Solution - Intravenous, Capsule, Capsule - Oral, Vaginal, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, film coated - Oral, Tablet, film coated, Gel - Vaginal, Tablet, film coated, extended release, Ointment - Topical, Insert - Vaginal, Insert, Kit, Tablet, extended release - Oral, Tablet, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated, Tablet, coated - Oral, Injection - Intravenous, Kit - Oral, Ointment

Bacterial Meningitis

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution, Solution - Intravenous, Capsule, Capsule - Oral, Vaginal, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, film coated - Oral, Tablet, film coated, Gel - Vaginal, Tablet, film coated, extended release, Ointment - Topical, Insert - Vaginal, Insert, Kit, Tablet, extended release - Oral, Tablet, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated, Tablet, coated - Oral, Injection - Intravenous, Kit - Oral, Ointment

Sinusitis

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution, Solution - Intravenous, Capsule, Capsule - Oral, Vaginal, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, film coated - Oral, Tablet, film coated, Gel - Vaginal, Tablet, film coated, extended release, Ointment - Topical, Insert - Vaginal, Insert, Kit, Tablet, extended release - Oral, Tablet, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated, Tablet, coated - Oral, Injection - Intravenous, Kit - Oral, Ointment

Endocarditis, Bacterial

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution, Solution - Intravenous, Capsule, Capsule - Oral, Vaginal, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, film coated - Oral, Tablet, film coated, Gel - Vaginal, Tablet, film coated, extended release, Ointment - Topical, Insert - Vaginal, Insert, Kit, Tablet, extended release - Oral, Tablet, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated, Tablet, coated - Oral, Injection - Intravenous, Kit - Oral, Ointment

Operative Surgical Procedures

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution, Solution - Intravenous, Capsule, Capsule - Oral, Vaginal, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, film coated - Oral, Tablet, film coated, Gel - Vaginal, Tablet, film coated, extended release, Ointment - Topical, Insert - Vaginal, Insert, Kit, Tablet, extended release - Oral, Tablet, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated, Tablet, coated - Oral, Injection - Intravenous, Kit - Oral, Ointment

Lockjaw

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution, Solution - Intravenous, Capsule, Capsule - Oral, Vaginal, Suppository, Suppository - Vaginal, Cream - Vaginal, Tablet, film coated - Oral, Tablet, film coated, Gel - Vaginal, Tablet, film coated, extended release, Ointment - Topical, Insert - Vaginal, Insert, Kit, Tablet, extended release - Oral, Tablet, extended release, Tablet, film coated, extended release - Oral, Suppository - Rectal, Rectal, Tablet, coated, Tablet, coated - Oral, Injection - Intravenous, Kit - Oral, Ointment

Warnings

Metrogel has three contraindications, and it should not be consumed if you have any of the circumstances given in the subsequent table.

Metrogel Contraindications

Condition

Risk Level

Notes

Severe Hypersensitivity Reactions

Do Not Combine

Metronidazole may interact with Pulse Frequency

Pregnancy Trimester, First

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Metronidazole may interact with Pulse Frequency

There are 20 known major drug interactions with Metrogel.

Common Metrogel Drug Interactions

Drug Name

Risk Level

Description

Abemaciclib

Major

The metabolism of Abemaciclib can be decreased when combined with Metronidazole.

Acalabrutinib

Major

The metabolism of Acalabrutinib can be decreased when combined with Metronidazole.

Alectinib

Major

The metabolism of Alectinib can be decreased when combined with Metronidazole.

Alpelisib

Major

The metabolism of Alpelisib can be decreased when combined with Metronidazole.

Aminophylline

Major

The metabolism of Aminophylline can be decreased when combined with Metronidazole.

Metrogel Toxicity & Overdose Risk

The highest amount of metronidazole that a rat can take without being toxic is 5000 mg/kg. Taking too much metronidazole can lead to nerve damage, trouble with the central nervous system, seizures, trouble digesting alcohol, dark urine, a bad taste in your mouth, nausea, stomach discomfort, and dizziness, as well as low levels of infection-fighting cells. If you take too much metronidazole, there is no specific remedy. You should get medical help and take activated charcoal to help remove the unabsorbed metronidazole from your body. It is also important to

image of a doctor in a lab doing drug, clinical research

Metrogel Novel Uses: Which Conditions Have a Clinical Trial Featuring Metrogel?

179 active trials are investigating the potential of Metrogel in alleviating Curling Ulcer, Periodontitis and Central Nervous System Bacterial Infections.

Condition

Clinical Trials

Trial Phases

Lockjaw

0 Actively Recruiting

Uterine Cervical Erosion

0 Actively Recruiting

Gum Disease

3 Actively Recruiting

Phase 3, Not Applicable

Abdominal Infection

0 Actively Recruiting

Rosacea

0 Actively Recruiting

Balantidiasis

0 Actively Recruiting

Empyema

1 Actively Recruiting

Phase 4

Abdominal Abscess

2 Actively Recruiting

Phase 4, Phase 1, Phase 2

Bacteria

0 Actively Recruiting

Trichomonas Infections

0 Actively Recruiting

Vulvovaginitis

0 Actively Recruiting

Lung Abscess

0 Actively Recruiting

Pouchitis

5 Actively Recruiting

Phase 2, Phase 3, Early Phase 1, Phase 4

Atopic Dermatitis

12 Actively Recruiting

Phase 2, Phase 3, Phase 4, Not Applicable

Acne Vulgaris

0 Actively Recruiting

Operative Surgical Procedures

0 Actively Recruiting

Liver Abscess, Amebic

0 Actively Recruiting

Trichomonas Vaginitis

2 Actively Recruiting

Phase 2, Phase 4

Amebic colitis

0 Actively Recruiting

Rosacea

2 Actively Recruiting

Early Phase 1, Phase 2

Metrogel Reviews: What are patients saying about Metrogel?

5

Patient Review

1/19/2016

Metrogel for Acne Rosacea

I had been struggling with rosacea for 10 months before I went to see my doctor. He prescribed me metrogel 3 weeks ago, and the results have been amazing. All of my pustules and papules have disappeared, and I now just have a small area of redness which is fading. Metrogel has literally been life-changing for me!

5

Patient Review

12/10/2017

Metrogel for Acne Rosacea

This product has helped me clear my skin and get rid of redness and pimples due to rosacea. I use generic but only in cream form since the gel does not work for me. Have been using it twice daily for the last 7--8 years with no side effects. I am a 64 yr old female.

5

Patient Review

6/10/2018

Metrogel for Acne Rosacea

I had a red/purple nose with acne as well as a red (rashed) forehead and cheeks. The results were immediate...I no longer have skin problems. I wash my face in the shower with water only...and apply metrogel cream right after. I am male and very happy with the results.

5

Patient Review

4/23/2015

Metrogel for Acne Rosacea

I had a rebound effect that was really uncomfortable. My face was red and hot, and it looked terrible.

5

Patient Review

7/20/2020

Metrogel for Acne Rosacea

I had rosacea for six months before seeing a dermatologist and being properly diagnosed. I tried out metrogel and, within three days, all my symptoms had completely cleared! I noticed an enormous difference after just the second day. This drug is nothing short of a miracle for me; it's also super cheap, which is amazing. Wish I had known about it sooner!

5

Patient Review

6/13/2016

Metrogel for Acne Rosacea

GP visit was very productive; I left with a prescription for metrogel. After a few weeks of use, my skin is now clear and soft. In Scotland, this repeat prescription is free which is amazing.

5

Patient Review

10/16/2017

Metrogel for Acne Rosacea

I got great results from this product, but $213 is a lot to spend on such a small tube. I wish my drug plan would cover the cost.

5

Patient Review

4/8/2016

Metrogel for Acne Rosacea

My doctor prescribed this to me after I expressed how much pain and discomfort I was in. After using it for only two days, there was a significant difference. I've been using it consistently for four weeks now and am still amazed at the results.

4.3

Patient Review

1/21/2016

Metrogel for Acne Rosacea

While I have perfectly good health care, my copay now costs over $200 which is outrageous and infuriating. I can't afford it now and as a result, my face looks horrible.

4

Patient Review

1/15/2020

Metrogel for Acne Rosacea

I was prescribed this for early onset rosacea. I started seeing results in just two days, which is amazing considering I've never had any skin problems other than the occasional pimple.

3.7

Patient Review

3/3/2015

Metrogel for Acne Rosacea

I found this gel to be drying of my skin. I actually made my rosacea look worse.

3.3

Patient Review

6/14/2016

Metrogel for Acne Rosacea

I saw a reduction in pustules after about a month, but then got a yeast infection. My OB-GYN said this was definitely the cause of the infection. Not worth it!

3

Patient Review

9/11/2016

Metrogel for Acne Rosacea

I'm not entirely sure if this is rosacea, but I do know that this cream has helped to reduce the redness and blotchiness by about half. It's also great because there is a generic version available.

2.3

Patient Review

9/4/2019

Metrogel for Acne Rosacea

I've been struggling with rosacea for a while now, and have found that Prosacea works well enough to keep it under control. However, during a recent flare-up my doctor prescribed me Metrogel. Unfortunately, this medication was entirely ineffective for me; I didn't see any difference at all after using it for three weeks on only half of my face as an experiment. Given that a tube costs around $140 CAD, it was quite a waste of money.

2

Patient Review

5/6/2015

Metrogel for Acne Rosacea

My dermatologist prescribed this, and it's been really tough to use. It burns my skin quite badly, feels like I'm putting fire on my face rather than an antibiotic cream. If anything, it seems to have made my Rosacea worse. On top of that, it's expensive.

2

Patient Review

1/18/2015

Metrogel for Acne Rosacea

1.3

Patient Review

10/2/2021

Metrogel for Acne Rosacea

I'm a 64 year old man who's never had skin problems before, and this very expensive gel didn't do anything for me. If anything, it made my rash worse. I only used it for three months (three tubes), but the symptoms came back as soon as I stopped using it. There are other treatments available that actually address the cause of rosacea, and those have proven effective for me.

1

Patient Review

4/21/2015

Metrogel for Acne Rosacea

I had a terrible reaction to this treatment. My face was bright red and it felt hot and uncomfortable. It looked bad, too.

1

Patient Review

5/17/2018

Metrogel for Acne Rosacea

This drug leaves my face feeling suffocated and uncomfortable. The pump is also difficult to use, often giving too much or too little medication. I believe that this drug should not be available for purchase.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about metrogel

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Can you use MetroGel on your face?

"Do not put it on cuts, scrapes, or sunburned skin.

Please consult your doctor if you have any questions. This medication is meant to be used externally only. Avoid contact with your eyes, nose, mouth, or vagina. Do not apply to open wounds, abrasions, or sunburned skin."

Answered by AI

What is MetroGel used for?

"This medication is used to treat rosacea, a type of adult acne, by reducing redness, swelling, and the number of pimples. It is a topical antibiotic."

Answered by AI

Is MetroGel and metronidazole the same thing?

"Flagyl, Flagyl ER, and Flagyl Injection are all different forms of the same antibiotic that is taken orally (by mouth) or intravenously (injected into a vein) to treat various conditions.

The drugs MetroGel, Flagyl, Flagyl ER, and Flagyl Injection are all forms of the antibiotic metronidazole. MetroGel is a topical gel used to treat skin lesions caused by rosacea, while Flagyl, Flagyl ER, and Flagyl Injection are taken orally or intravenously to treat various other conditions."

Answered by AI

How long does it take for MetroGel to work?

"It takes 3 to 4 weeks for Metrogel (metronidazole) to start working. You should see a significant improvement in your symptoms by then."

Answered by AI

Clinical Trials for Metrogel

Image of ALS Global in Irving, United States.

GX-03 for Eczema

18 - 70
All Sexes
Irving, TX

This is a randomized, double-blind, vehicle-controlled clinical study designed to evaluate the efficacy and safety of GX-03, a topically applied emollient, in adult subjects with moderate to severe eczema. Approximately 120 adult participants will be enrolled and randomized in a 1:1 ratio to receive either GX-03 or a petrolatum-based vehicle control for 8 consecutive weeks. Efficacy will be assessed using validated clinical outcome measures, including the Eczema Area and Severity Index (EASI), the Validated Investigator Global Assessment for Atopic Dermatitis (vIGA-AD™), and the Peak Pruritus Numeric Rating Scale (PP-NRS). Safety will be evaluated through monitoring of treatment-emergent adverse events throughout the study period.

Phase 2
Recruiting

ALS Global

Turn Therapeutics

Image of Seeding Labs INC in Austin, United States.

Tailored Recommendations for Infant Gut Microbiome

No minimum age - 3
All Sexes
Austin, TX

The goal of this clinical trial is to learn whether microbiome analysis, education, and personalized recommendations can improve gut health and reduce early markers of immune-related conditions in infants aged 0-3 months delivered via Cesarean section. The study aims to determine whether these interventions can increase beneficial bacteria, decrease C-section-associated microbiome signatures, reduce opportunistic pathogens, and improve functional potential for HMO digestion and SCFA production. The study also seeks to assess whether improvements in microbiome composition are associated with a reduced prevalence of early atopic symptoms. Researchers will compare three groups: a full intervention arm that receives microbiome reports, coaching, personalized recommendations, and educational materials; a limited intervention arm that receives simplified reports and basic recommendations; and a control arm that receives no results until study completion. This design allows evaluation of both a comprehensive intervention and a more scalable, minimal-results model. Participants will: 1. Provide six microbiome stool samples over a 24-month period. 2. Provide additional small stool samples at two timepoints for exploratory metabolomic analysis. 3. Receive microbiome reports and guidance according to their assigned study arm. 4. Complete surveys on infant health history, symptoms, diet, and environmental exposures. 5. Participate in standardized eczema assessment(s) administered by a Nurse Practitioner and evaluated by a Pediatric Allergy Specialist if any symptoms are reported. This study seeks to demonstrate that targeted microbiome support can positively shift gut microbial development in C-section infants and may reduce risks linked to the early stages of the atopic march. Findings may inform scalable strategies for delivering microbiome-based support in early life and improve long-term health outcomes for this high-risk population.

Waitlist Available
Has No Placebo

Seeding Labs INC

Qian Yuan, MD

Seeding, Inc DBA Tiny Health

Image of Children's of Alabama in Birmingham, United States.

Antibiotic Duration for Infections in Children

60 - 17
All Sexes
Birmingham, AL

Infections like pneumonia, skin and soft tissue infection (also called SSTI or cellulitis), and urinary tract infections (UTI) are some of the most common reasons children get admitted to the hospital. All three of these conditions require antibiotics for treatment. Although antibiotics are needed to treat the infection and help children feel better, taking them longer than needed can negatively impact children and their families. Negative impacts include things like the burdens of taking more medications and medication side effects. There are guidelines (instructions) from expert medical organizations that suggest the number of days children need antibiotics, but they give a wide range (between 5 and 14 days). Unfortunately, these guidelines are not based on high-quality studies. National data suggests that doctors often choose on the higher end of this range when writing prescriptions for children in the hospital. Our three caregiver co-investigators, other parents of hospitalized children, doctors, other care providers, and researchers, all believe that additional study is needed to determine the best length of antibiotic treatment that weighs both the benefits and harms of antibiotics. The goal of our study is to understand if 5 total days of antibiotic treatment compared to 10 total days of antibiotic treatment is better for children who have been in the hospital for pneumonia, SSTI, or UTI. We will study this question through a randomized control trial. In other words, half of the children will receive 5-days of antibiotics and the other half will receive 10-days of antibiotics. Children in this study (and their caregivers) will not know how many days of antibiotics they will receive to cure their infection because some children will take a placebo (or a pill without antibiotics in it). Only the pharmacy will know if a child is getting antibiotic or placebo (for days 6-10 of treatment). During the first phase of the trial (feasibility phase), 4 hospitals will enroll children in the study. We plan on enrolling 50 patients during this phase. We are starting with just 4 hospitals, so our study team can create and update our study plans if needed. We will closely review information about how many patients and families agree to participate, and if they have any trouble completing any part of the study. We will also interview families to understand the choice to participate in the study, the choice not to participate in the study, and what it is like to be in the study. During the second study phase, we will enroll 1150 more patients across all 11 hospitals. Families will complete short, daily surveys until the 15th day after they started antibiotics, then a larger survey at day 15, at day 20, and at day 30. These surveys will ask about the child's symptoms and recovery from their illness, how the antibiotics are making them feel, and if they had to go back to their doctor, emergency room, or hospital. The answers to these questions will be combined to measure how well the child did, balancing feeling better and having bad effects from the antibiotics. We will use mathematical tests to determine which antibiotic duration is better for treating these illnesses. We will complete other mathematical tests to see if all children should receive the same length of antibiotics or if certain children should be prescribed shorter courses and others longer courses.

Phase 4
Waitlist Available

Children's of Alabama (+9 Sites)

Sunitha V Kaiser, MD, MSc

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Image of UNC Chapel Hill in Chapel Hill, United States.

Intrapleural Enzyme Therapy for Pleural Infection

18+
All Sexes
Chapel Hill, NC

The goal of this clinical trial is to find out if giving certain medications once a day works just as well as giving them twice a day to treat infections around the lungs (called pleural infections). These medications-tissue plasminogen activator (tPA) and deoxyribonuclease (DNase)-are placed through a chest tube into the space between the lung and the chest wall to help clear out the infection. The investigators are trying to learn: * Does using the medicine once a day work just as well as using it twice a day? * Are there any differences in outcomes between patients who get the medicine once a day versus twice a day? * Does more or less fluid remain in the chest (seen on a chest x-ray) depending on how often the medicine is given? Participants will: * Have an infection around their lung and will already be getting normal hospital care, including a chest tube to drain the infected fluid around their lung. * Be asked to give permission to join the study. * Be randomly chosen (like flipping a coin) to get the medications either once a day or twice a day through the chest tube.

Phase 4
Waitlist Available

UNC Chapel Hill

Jason Akulian, MD, MPH

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We made a collection of clinical trials featuring Metrogel, we think they might fit your search criteria.
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Image of Office of Dental Health, Department of Health and Senior Services in Jefferson City, United States.

Dental Care for Pneumonia Prevention

60 - 100
All Sexes
Jefferson City, MO

The goal of this study is to learn if dental infection control treatment delivered to older adult nursing home residents at their place of residence will result in : * improved dental health * reduced risk of pneumonia * better glucose control for diabetic patients compared to the pre-project dental and general health evaluations of residents and the pre-project facility incidence of pneumonia. Dental infection control treatment includes treating gum infections, stopping or slowing decay with fluoride, and assisting residents with effective tooth brushing and denture cleaning daily. Previous studies indicate dental infections can be inhaled and cause pneumonia or make diabetes worse. A shortage of dentists has limited care for nursing home residents. This project will allow dental hygienists and specially trained dental assistants to treat nursing home residents using telehealth methods (computers, cameras, internet, and telephone) to talk and work with dentists in different locations.

Recruiting
Has No Placebo

Office of Dental Health, Department of Health and Senior Services

Have you considered Metrogel clinical trials?

We made a collection of clinical trials featuring Metrogel, we think they might fit your search criteria.
Go to Trials