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What is Meloxicam
MeloxicamThe Generic name of this drug
Treatment SummaryMeloxicam is a type of medication used to reduce pain caused by musculoskeletal conditions, osteoarthritis, and rheumatoid arthritis. It works by blocking the production of certain enzymes that cause inflammation. It is longer-lasting than other NSAIDs and only needs to be taken once a day. Meloxicam comes in oral, transdermal, and intravenous forms and is believed to be less likely to cause gastrointestinal side effects than other NSAIDs.
Mobicis the brand name
Meloxicam Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Mobic
Meloxicam
2000
284
Effectiveness
How Meloxicam Affects PatientsMeloxicam is a painkiller with fever-reducing effects, and has been shown to reduce inflammation in those with rheumatoid arthritis. Similar to other NSAIDs, taking meloxicam long-term can lead to issues with the kidneys or the cardiovascular system. While meloxicam is believed to have less gastrointestinal side effects than other NSAIDs, it can still lead to inflammation, bleeding, and ulcers. One study found that 13% of patients taking meloxicam suffered these side effects compared to 19% of those taking the NSAID diclofenac. However, the side effects in patients taking meloxic
How Meloxicam works in the bodyMeloxicam works to reduce pain and inflammation by inhibiting the production of prostaglandins. Prostaglandins are molecules that activate pain receptors in the body, so reducing their production helps to reduce pain and inflammation. Meloxicam specifically targets the enzymes responsible for producing prostaglandins, most notably the COX-2 enzyme, but also has some effect on COX-1, which can lead to gastrointestinal irritation.
When to interrupt dosage
The recommended measure of Meloxicam is contingent upon the diagnosed condition, including Therapeutic procedure, Osteoarthritis (OA) and Dental Pain. The level of dosage is contingent upon the mode of administration (e.g. Suspension or Kit) found in the table underneath.Condition
Dosage
Administration
Neuropathic Pain
, 7.5 mg/mL, 7.5 mg, 15.0 mg, 5.0 mg, 10.0 mg, 30.0 mg/mL, 6.0 mg, 12.0 mg, 1.8 mg, 1.8 mg/mL, 0.9 mg/mL, 1.2 mg/mL, 6.0 mg/mL
, Suspension, Oral, Suspension - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Kit, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection - Intravenous, Injection, Intravenous, Kit - Oral, Solution, Intralesional, Solution - Intralesional, Oral; Topical, Kit - Oral; Topical, Infiltration, Solution - Infiltration
Dental Pain
, 7.5 mg/mL, 7.5 mg, 15.0 mg, 5.0 mg, 10.0 mg, 30.0 mg/mL, 6.0 mg, 12.0 mg, 1.8 mg, 1.8 mg/mL, 0.9 mg/mL, 1.2 mg/mL, 6.0 mg/mL
, Suspension, Oral, Suspension - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Kit, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection - Intravenous, Injection, Intravenous, Kit - Oral, Solution, Intralesional, Solution - Intralesional, Oral; Topical, Kit - Oral; Topical, Infiltration, Solution - Infiltration
Pauciarticular juvenile rheumatoid arthritis
, 7.5 mg/mL, 7.5 mg, 15.0 mg, 5.0 mg, 10.0 mg, 30.0 mg/mL, 6.0 mg, 12.0 mg, 1.8 mg, 1.8 mg/mL, 0.9 mg/mL, 1.2 mg/mL, 6.0 mg/mL
, Suspension, Oral, Suspension - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Kit, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection - Intravenous, Injection, Intravenous, Kit - Oral, Solution, Intralesional, Solution - Intralesional, Oral; Topical, Kit - Oral; Topical, Infiltration, Solution - Infiltration
Ankle
, 7.5 mg/mL, 7.5 mg, 15.0 mg, 5.0 mg, 10.0 mg, 30.0 mg/mL, 6.0 mg, 12.0 mg, 1.8 mg, 1.8 mg/mL, 0.9 mg/mL, 1.2 mg/mL, 6.0 mg/mL
, Suspension, Oral, Suspension - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Kit, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection - Intravenous, Injection, Intravenous, Kit - Oral, Solution, Intralesional, Solution - Intralesional, Oral; Topical, Kit - Oral; Topical, Infiltration, Solution - Infiltration
Polyarticular juvenile rheumatoid arthritis, chronic or unspecified
, 7.5 mg/mL, 7.5 mg, 15.0 mg, 5.0 mg, 10.0 mg, 30.0 mg/mL, 6.0 mg, 12.0 mg, 1.8 mg, 1.8 mg/mL, 0.9 mg/mL, 1.2 mg/mL, 6.0 mg/mL
, Suspension, Oral, Suspension - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Kit, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection - Intravenous, Injection, Intravenous, Kit - Oral, Solution, Intralesional, Solution - Intralesional, Oral; Topical, Kit - Oral; Topical, Infiltration, Solution - Infiltration
Peptic Ulcer
, 7.5 mg/mL, 7.5 mg, 15.0 mg, 5.0 mg, 10.0 mg, 30.0 mg/mL, 6.0 mg, 12.0 mg, 1.8 mg, 1.8 mg/mL, 0.9 mg/mL, 1.2 mg/mL, 6.0 mg/mL
, Suspension, Oral, Suspension - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Kit, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection - Intravenous, Injection, Intravenous, Kit - Oral, Solution, Intralesional, Solution - Intralesional, Oral; Topical, Kit - Oral; Topical, Infiltration, Solution - Infiltration
Osteoarthritis (OA)
, 7.5 mg/mL, 7.5 mg, 15.0 mg, 5.0 mg, 10.0 mg, 30.0 mg/mL, 6.0 mg, 12.0 mg, 1.8 mg, 1.8 mg/mL, 0.9 mg/mL, 1.2 mg/mL, 6.0 mg/mL
, Suspension, Oral, Suspension - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Kit, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection - Intravenous, Injection, Intravenous, Kit - Oral, Solution, Intralesional, Solution - Intralesional, Oral; Topical, Kit - Oral; Topical, Infiltration, Solution - Infiltration
Therapeutic procedure
, 7.5 mg/mL, 7.5 mg, 15.0 mg, 5.0 mg, 10.0 mg, 30.0 mg/mL, 6.0 mg, 12.0 mg, 1.8 mg, 1.8 mg/mL, 0.9 mg/mL, 1.2 mg/mL, 6.0 mg/mL
, Suspension, Oral, Suspension - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Kit, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection - Intravenous, Injection, Intravenous, Kit - Oral, Solution, Intralesional, Solution - Intralesional, Oral; Topical, Kit - Oral; Topical, Infiltration, Solution - Infiltration
Pain
, 7.5 mg/mL, 7.5 mg, 15.0 mg, 5.0 mg, 10.0 mg, 30.0 mg/mL, 6.0 mg, 12.0 mg, 1.8 mg, 1.8 mg/mL, 0.9 mg/mL, 1.2 mg/mL, 6.0 mg/mL
, Suspension, Oral, Suspension - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Kit, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection - Intravenous, Injection, Intravenous, Kit - Oral, Solution, Intralesional, Solution - Intralesional, Oral; Topical, Kit - Oral; Topical, Infiltration, Solution - Infiltration
Postoperative Pain
, 7.5 mg/mL, 7.5 mg, 15.0 mg, 5.0 mg, 10.0 mg, 30.0 mg/mL, 6.0 mg, 12.0 mg, 1.8 mg, 1.8 mg/mL, 0.9 mg/mL, 1.2 mg/mL, 6.0 mg/mL
, Suspension, Oral, Suspension - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Kit, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection - Intravenous, Injection, Intravenous, Kit - Oral, Solution, Intralesional, Solution - Intralesional, Oral; Topical, Kit - Oral; Topical, Infiltration, Solution - Infiltration
Rheumatoid Arthritis
, 7.5 mg/mL, 7.5 mg, 15.0 mg, 5.0 mg, 10.0 mg, 30.0 mg/mL, 6.0 mg, 12.0 mg, 1.8 mg, 1.8 mg/mL, 0.9 mg/mL, 1.2 mg/mL, 6.0 mg/mL
, Suspension, Oral, Suspension - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Kit, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection - Intravenous, Injection, Intravenous, Kit - Oral, Solution, Intralesional, Solution - Intralesional, Oral; Topical, Kit - Oral; Topical, Infiltration, Solution - Infiltration
Open Abdominal Surgery
, 7.5 mg/mL, 7.5 mg, 15.0 mg, 5.0 mg, 10.0 mg, 30.0 mg/mL, 6.0 mg, 12.0 mg, 1.8 mg, 1.8 mg/mL, 0.9 mg/mL, 1.2 mg/mL, 6.0 mg/mL
, Suspension, Oral, Suspension - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Kit, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection - Intravenous, Injection, Intravenous, Kit - Oral, Solution, Intralesional, Solution - Intralesional, Oral; Topical, Kit - Oral; Topical, Infiltration, Solution - Infiltration
Warnings
Meloxicam ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Meloxicam may interact with Pulse Frequency
Coronary Artery Bypass Surgery
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Meloxicam may interact with Pulse Frequency
Severe Hypersensitivity Reactions
Do Not Combine
Meloxicam may interact with Pulse Frequency
Common Meloxicam Drug Interactions
Drug Name
Risk Level
Description
Acetylsalicylic acid
Major
The risk or severity of gastrointestinal bleeding can be increased when Meloxicam is combined with Acetylsalicylic acid.
Macimorelin
Major
The therapeutic efficacy of Macimorelin can be decreased when used in combination with Meloxicam.
Mifamurtide
Major
The therapeutic efficacy of Mifamurtide can be decreased when used in combination with Meloxicam.
Neomycin
Major
The risk or severity of nephrotoxicity can be increased when Meloxicam is combined with Neomycin.
Omacetaxine mepesuccinate
Major
The risk or severity of bleeding can be increased when Meloxicam is combined with Omacetaxine mepesuccinate.
Meloxicam Toxicity & Overdose RiskThe toxic dose of meloxicam for rats is 98 mg/kg. Signs of overdose include difficulty breathing, seizures, decreased urination, and gastrointestinal issues such as nausea, vomiting, and bleeding. Treatment for an overdose may involve supportive care and removal of the stomach contents. Taking cholestyramine can help to remove meloxicam from the body.
Meloxicam Novel Uses: Which Conditions Have a Clinical Trial Featuring Meloxicam?
118 active clinical trials are currently assessing the potential of Meloxicam to alleviate Ankle, Post-Operative Abdominal Pain and Pain.Condition
Clinical Trials
Trial Phases
Dental Pain
0 Actively Recruiting
Rheumatoid Arthritis
61 Actively Recruiting
Not Applicable, Phase 4, Phase 3, Phase 2, Phase 1
Peptic Ulcer
0 Actively Recruiting
Pauciarticular juvenile rheumatoid arthritis
0 Actively Recruiting
Therapeutic procedure
0 Actively Recruiting
Polyarticular juvenile rheumatoid arthritis, chronic or unspecified
0 Actively Recruiting
Osteoarthritis (OA)
0 Actively Recruiting
Ankle
0 Actively Recruiting
Pain
1 Actively Recruiting
Phase 1
Open Abdominal Surgery
0 Actively Recruiting
Neuropathic Pain
27 Actively Recruiting
Phase 1, Phase 2, Phase 3, Not Applicable, Phase 4
Postoperative Pain
21 Actively Recruiting
Phase 4, Phase 1, Not Applicable, Phase 3, Early Phase 1, Phase 2
Meloxicam Reviews: What are patients saying about Meloxicam?
5Patient Review
4/29/2022 This is working great for both my shoulder joints and my calf muscles! I am 64 years old, couldn't mark it on the info place.
5Patient Review
3/28/2022 Meloxicam is much more effective than ibuprofen or Aleve for me, and I don't have any side effects that I've noticed. However, I only take it occasionally to limit my risk of developing problems.
5Patient Review
3/28/2022 Meloxicam is much more effective than ibuprofen or Aleve for me, and I don't experience any negative side effects. However, I limit my usage to reduce the likelihood of developing any in the future.
5Patient Review
4/29/2022 I'm 64 years old and this has been working great for both my shoulder joints and calf muscles!
5Patient Review
6/10/2022 This treatment is highly effective and has made my life much better.
5Patient Review
6/10/2022 This treatment is highly effective and has made my life much better.
4.7Patient Review
10/17/2022 This medication has been really effective for me in treating my osteo-arthritis and old herniated disk injury. I find that it takes away the pain within a few days, and exercise definitely helps as well!
4.7Patient Review
10/17/2022 I've found meloxicam to be really effective for my osteo-arthritis and lower back pain. It usually takes a few days to work, but the relief is definitely worth it! I highly recommend this medication.
2.3Patient Review
5/20/2022 I have a meniscal tear and rheumatoid arthritis. I was first given Celebrex which worked wonders but then it made me feel sick after about a week. I was then prescribed Meloxicam which I was already hesitant to try. On the 2nd day, I had severe abdominal pain and got so dizzy I thought I was about to pass out.
2.3Patient Review
5/20/2022 I was originally given Celebrex for my meniscal tear and rheumatoid arthritis, which worked great at first. However, I started to feel nauseous after about a week of use. Meloxicam was the next prescription, which I was hesitant to try due to its reputation. Unfortunately, I had severe abdominal pain and felt incredibly dizzy on the second day of use.
1.3Patient Review
4/29/2022 I was prescribed this for my osteoarthritis pain and stiffness, but it did nothing to help. If anything, it made me feel worse with nausea and headaches. Plus, the potential side effects are incredibly dangerous. I'll stick with aspirin and icing instead.
1.3Patient Review
10/29/2022 I tried monoxicam for a week, but it actually led to more pain in my lower back. I won't be using this again.
1.3Patient Review
4/29/2022 I was prescribed this for my osteoarthritis pain and stiffness, but it didn't help at all. If anything, it made my symptoms worse. I felt nauseous and got headaches, on top of the fact that the side effects include heart attack and stroke! No thanks, I'll stick with aspirin and icing.
1.3Patient Review
10/29/2022 I tried this for a week and found that it actually made my lower back pain worse. I wouldn't recommend it to anyone.
1Patient Review
5/30/2022 I unfortunately cannot speak to the effectiveness of this medication because I had to stop taking it due to how sick it made me. Side effects included: stomach pain, nausea, and cramps. If you're considering this medication, good luck.
1Patient Review
4/29/2022 The dangers of this drug outweigh any potential benefits. I experienced no relief from taking it for my osteoarthritis, but did suffer from stomach upset, nausea, and headaches.
1Patient Review
4/17/2022 This medicine caused my mom a lot of trouble- she needed hospitalization and blood transfusions to recover from the stomach bleeding it caused. It also didn't do much to help her arthritis pain.
1Patient Review
4/29/2022 The dangers of this drug far outweigh any benefits. It didn't work for me, and caused a whole host of other problems.
1Patient Review
5/30/2022 Unfortunately, I cannot attest to the effectiveness of this medication as I had to stop taking it due to the severe side effects. Within hours of taking the first dose, I was experiencing intense nausea and vomiting, stomach pain, and cramps. If you're considering this medication, good luck - I hope it works better for you than it did for me.
1Patient Review
4/17/2022 This medicine caused my mom a lot of pain and she needed to go to the hospital. It also didn't help with her arthritis that much.
Patient Q&A Section about meloxicam
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What are the side effects of taking meloxicam?
"adominal pain, diarrhea, indigestion or heartburn, nausea, dizziness, headache, itching or rash"
Answered by AI
Is meloxicam a strong painkiller?
"Meloxicam is a strong painkiller that must be prescribed by a doctor. It can come as a regular tablet, disintegrating tablet, capsule, or oral suspension liquid. Some popular brand names of meloxicam include Mobic, Vivlodex, Qmiiz ODT, and Comfort Pac-Meloxicam."
Answered by AI
Is ibuprofen or meloxicam stronger?
"There are several key differences between meloxicam and ibuprofen. Meloxicam is considered a stronger medicine, and is only available by prescription. In contrast, ibuprofen is available both over-the-counter and by prescription. Meloxicam is also a long-acting medication, meaning it only needs to be given once a day."
Answered by AI