Kenalog In Orabase

Macular Edema, Stomatitis, Denture, Ophthalmia, Sympathetic + 113 more

Treatment

16 FDA approvals

20 Active Studies for Kenalog In Orabase

Treatment for

Macular Edema

What is Kenalog In Orabase

Triamcinolone

The Generic name of this drug

Treatment Summary

Triamcinolone is a type of steroid medication used to treat inflammation from a variety of conditions, such as allergic rhinitis and multiple sclerosis. It can be taken as a one-time treatment for knee pain related to osteoarthritis or used topically for conditions that respond to corticosteroid treatments. There are several forms of triamcinolone, including triamcinolone hexacetonide, triamcinolone acetonide, and triamcinolone diacetate. The FDA approved triamcinolone in 1957, and in 2021 they approved a suspension of triamcin

Aristocort

is the brand name

Kenalog In Orabase Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Aristocort

Triamcinolone

1961

532

Approved as Treatment by the FDA

Triamcinolone, also called Aristocort, is approved by the FDA for 16 uses which include Lichen Planus and Ganglia .

Lichen Planus

Helps manage Lichen Planus (LP)

Ganglia

Helps manage cystic tumour of the ganglia

Granuloma Annulare

Helps manage granuloma annulare lesions

Psoriasis

Helps manage Psoriatic plaque

Neurodermatitis

Helps manage Lichen simplex chronicus

Lupus Erythematosus, Discoid

Helps manage Discoid Lupus Erythematosus (DLE)

granuloma annulare lesions

Helps manage granuloma annulare lesions

cystic tumour of the ganglia

Helps manage cystic tumour of the ganglia

Lichen simplex chronicus

Helps manage Lichen simplex chronicus

Lichen Planus (LP)

Helps manage Lichen Planus (LP)

Discoid Lupus Erythematosus (DLE)

Helps manage Discoid Lupus Erythematosus (DLE)

Alopecia Areata (AA)

Helps manage Alopecia Areata (AA)

Keloids Scars

Helps manage Keloids Scars

Necrobiosis Lipoidica

Helps manage Necrobiosis lipoidica diabeticorum

Alopecia Areata

Helps manage Alopecia Areata (AA)

Psoriatic plaque

Helps manage Psoriatic plaque

Effectiveness

How Kenalog In Orabase Affects Patients

Triamcinolone is a type of steroid medicine used to reduce inflammation in various parts of the body. It should not be injected directly into the spine.

How Kenalog In Orabase works in the body

Triamcinolone works as an anti-inflammatory to reduce swelling and redness. It does this by blocking the breakdown of lysosomal membranes of leukocytes, which prevents the formation of arachidonic acid. This stops the production of prostaglandins and leukotrienes, which are signals that cause dilation of blood vessels and increased permeability. Triamcinolone also limits the production of pro-inflammatory signals, such as interleukin-6, interleukin-8, and monocyte chemoattractant protein-1, by blocking nuclear factor kappa-

When to interrupt dosage

The amount of Kenalog In Orabase is contingent upon the determined condition, including Mycosis Fungoides (MF), Mycoses and Alopecia Areata (AA). The measure additionally differs as per the strategy of administration (e.g. Ointment or Injection, suspension - Intralesional; Parenteral) outlined in the accompanying table.

Condition

Dosage

Administration

Skin Diseases

, 40.0 mg/mL, 10.0 mg/mL, 0.055 mg, 0.001 mg/mg, 0.25 mg/mL, 1.0 mg/mL, 0.0005 mg/mg, 0.00025 mg/mg, 0.005 mg/mg, 5.0 mg/mL, 20.0 mg/mL, 0.000147 mg/mg, 0.5 mg/mL, 40.0 mg, 1.0 mg, 0.000025 mg/mg, 0.1 %, 0.025 %, 5.0 mg, 0.25 mg, 2.0 mg, 4.0 mg, 0.5 %, 15.0 mg/mL, 6.5 mg, 80.0 mg/mL, 0.075 mg, 200.0 mg/mL, 32.0 mg, 0.055 mg/dose, 0.5 mg, 0.2 mg/pump actuation, 0.1 mg/dose, 25.0 mg/mL, 0.055 mg/pump actuation, 2.0 mg/mL, 0.4 mg/mL

Injection, suspension, Intra-articular; Intramuscular, Injection, suspension - Intra-articular; Intramuscular, , Injection, suspension - Intra-articular; Intralesional, Intra-articular; Intralesional, Spray, metered, Nasal, Spray, metered - Nasal, Lotion, Lotion - Topical, Ointment, Topical, Ointment - Topical, Cream, Cream - Topical, Injection, suspension - Intralesional; Parenteral, Intra-articular; Parenteral, Injection, suspension - Intra-articular; Parenteral, Aerosol, spray, Aerosol, spray - Topical, Paste - Topical, Paste, Kit, Dental, Paste - Dental, Intra-articular; Intrabursal; Intradermal; Intrasynovial, Suspension - Intra-articular; Intrabursal; Intradermal; Intrasynovial, Intralesional, Suspension - Intralesional, Suspension, Aerosol, metered - Respiratory (inhalation), Respiratory (inhalation), Intra-articular, Suspension - Intra-articular, Oral, Tablet, Tablet - Oral, Kit - Epidural; Infiltration; Intra-articular; Intramuscular; Topical, Epidural; Infiltration; Intra-articular; Intramuscular; Topical, Ophthalmic, Intralesional; Parenteral, Intra-articular; Intrabursal; Intradermal; Intralesional, Injection, suspension - Intra-articular; Intrabursal; Intradermal; Intralesional, Intramuscular, Injection, suspension - Intramuscular, Suspension - Intra-articular; Intramuscular, Suspension - Intra-articular; Intrabursal; Intramuscular, Intra-articular; Intrabursal; Intramuscular, Aerosol, metered - Nasal, Aerosol, metered, Intra-articular; Intramuscular; Intrasynovial, Liquid - Intra-articular; Intramuscular; Intrasynovial, Intra-articular; Intradermal; Intramuscular, Syrup - Oral, Syrup, Suspension - Intramuscular, Liquid, Liquid - Intra-articular; Intradermal; Intramuscular, Intra-articular; Intradermal; Intralesional; Intramuscular, Suspension - Intra-articular; Intradermal; Intralesional; Intramuscular, Spray, suspension - Nasal, Injection, solution, Injection, solution - Intra-articular; Intramuscular, Injection, suspension - Ophthalmic, Intravitreal, Infiltration; Intra-articular; Intramuscular; Respiratory (inhalation); Topical, Spray - Topical, Spray, Intra-articular; Intrasynovial; Periarticular, Suspension - Intra-articular; Intrasynovial; Periarticular, Kit - Intra-articular; Intramuscular, Suspension - Ophthalmic, Subcutaneous, Implant - Subcutaneous, Implant, Kit - Epidural; Infiltration; Intra-articular; Intramuscular, Injection, suspension - Intra-articular; Intramuscular; Intravitreal, Intra-articular; Intramuscular; Intravitreal, Epidural; Infiltration; Intra-articular; Intramuscular, Epidural; Infiltration; Intra-articular; Intralesional, Intra-articular; Intralesional; Intramuscular; Intrasynovial; Parenteral, Injection, suspension - Intra-articular; Intralesional; Intramuscular; Intrasynovial; Parenteral, Kit - Intra-articular, Infiltration; Soft tissue; Topical, Kit - Infiltration; Soft tissue; Topical, Suspension - Intravitreal, Kit - Infiltration; Intra-articular; Intramuscular; Respiratory (inhalation); Topical, Kit - Epidural; Intra-articular; Intramuscular; Topical, Epidural; Intra-articular; Intramuscular; Topical, Kit - Epidural; Infiltration; Intra-articular; Intralesional, Paste, dentifrice, Paste, dentifrice - Dental, Ointment - Buccal, Buccal, Emulsion, Gel, Emulsion - Topical, Gel - Topical, Intra-articular; Intramuscular; Topical, Kit - Topical, Injection, suspension - Intra-articular, Infiltration; Intra-articular; Intramuscular; Topical, Kit - Infiltration; Intra-articular; Intramuscular; Topical

Lupus Erythematosus

Ankylosing Spondylitis

Hand

Stomatitis, Denture

Hypercalcemia

induction of Diuresis

Proteinuria

Atopic Dermatitis

Craniotomy

Thrombocytopenia

Bullous dermatitis herpetiformis

Thyroiditis

Congenital adrenal hyperplasia

Trichinosis

Ganglia

Dermatomyositis

Neuralgia, Postherpetic

Hemangioma

Wound Infection

Warnings

Kenalog In Orabase has four contraindications. It should not be employed in cases when any of the conditions given in the following table are present.

Kenalog In Orabase Contraindications

Condition

Risk Level

Notes

Severe Hypersensitivity Reactions

Do Not Combine

Triamcinolone may interact with Pulse Frequency

Mycoses

Do Not Combine

active periocular infections

Do Not Combine

Eye Infections

Do Not Combine

There are 20 known major drug interactions with Kenalog In Orabase.

Common Kenalog In Orabase Drug Interactions

Drug Name

Risk Level

Description

2-Methoxyethanol

Major

The risk or severity of adverse effects can be increased when Triamcinolone is combined with 2-Methoxyethanol.

9-(N-methyl-L-isoleucine)-cyclosporin A

Major

The risk or severity of adverse effects can be increased when Triamcinolone is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.

Abemaciclib

Major

The metabolism of Abemaciclib can be increased when combined with Triamcinolone.

Abetimus

Major

The risk or severity of adverse effects can be increased when Triamcinolone is combined with Abetimus.

Acalabrutinib

Major

The metabolism of Acalabrutinib can be increased when combined with Triamcinolone.

Kenalog In Orabase Toxicity & Overdose Risk

The lowest toxic dose of triamcinolone acetonide in rats is 13,100µg/kg and 132mg/kg in mice. The lowest toxic dose of triamcinolone acetonide taken orally in rats is 1451mg/kg and 2168mg/kg in mice, and 105mg/kg for mice taken intraperitoneally. Overdosing on triamcinolone acetonide may cause Cushing's syndrome, which can be treated with supportive therapy and a medication called mifepristone.

image of a doctor in a lab doing drug, clinical research

Kenalog In Orabase Novel Uses: Which Conditions Have a Clinical Trial Featuring Kenalog In Orabase?

1076 active investigations are being conducted to assess the potential of Kenalog In Orabase for alleviating symptoms of Lupus, Atopic Dermatitis and Brain Metastases.

Condition

Clinical Trials

Trial Phases

Macular Edema

1 Actively Recruiting

Phase 2

Asthma

84 Actively Recruiting

Phase 1, Phase 4, Early Phase 1, Not Applicable, Phase 2, Phase 3

Anemia, Hemolytic, Autoimmune

0 Actively Recruiting

Rheumatoid Arthritis

56 Actively Recruiting

Not Applicable, Phase 3, Phase 1, Phase 2, Phase 4

Vitrectomy therapy

0 Actively Recruiting

Dermatitis, Seborrheic

0 Actively Recruiting

Crohn's Disease

52 Actively Recruiting

Phase 1, Phase 2, Not Applicable, Phase 3, Phase 4, Early Phase 1

Metastatic Brain Tumors

55 Actively Recruiting

Not Applicable, Phase 1, Phase 2, Phase 3, Early Phase 1, Phase 4

Thyroiditis

0 Actively Recruiting

Brain

0 Actively Recruiting

Stomatitis

0 Actively Recruiting

Dermatitis

0 Actively Recruiting

Tinea

0 Actively Recruiting

Conjunctivitis, Bacterial

0 Actively Recruiting

Tenosynovitis

0 Actively Recruiting

Mycoses

0 Actively Recruiting

Synovitis

1 Actively Recruiting

Phase 4

Dermatitis, Allergic Contact

0 Actively Recruiting

Keloids Scars

1 Actively Recruiting

Phase 3

Ulcer

0 Actively Recruiting

Kenalog In Orabase Reviews: What are patients saying about Kenalog In Orabase?

Patient Review

2/24/2010

Kenalog In Orabase for Canker Sore

I've been using this medication for years, and it's the only one I've found that actually works to relieve canker sore pain and shorten their duration.

Patient Review

9/12/2017

Kenalog In Orabase for Canker Sore

I've been using this since I was 7, and it's still the best medication for mouth ulcers that I've found. Very happy with the results!

Patient Review

4/24/2018

Kenalog In Orabase for Canker Sore

I got this while on vacation in Australia and it was a total lifesaver. If you have canker sores, I highly recommend getting this medication.

Patient Review

2/6/2010

Kenalog In Orabase for Canker Sore

I have a partial dental plate and sometimes get a sore spot. This product works great, but the packaging is too small.

4.7

Patient Review

4/12/2019

Kenalog In Orabase for Canker Sore

I've been using this paste for a long time and it's always worked great for me. It numbs better than any other gel I've tried.

4.3

Patient Review

8/12/2012

Kenalog In Orabase for Canker Sore

I have been using this medication for mouth ulcers since I was a child. It is the best and quickest fix for mouth ulcers that I have found.

3.3

Patient Review

10/1/2020

Kenalog In Orabase for Gum Disease

It was difficult to figure out how to use this product, but once I did, it really helped ease the pain around my wisdom teeth. The numbing effect lasted a few hours, which was great considering I don't like taking painkillers.

3.3

Patient Review

8/10/2008

Kenalog In Orabase for Canker Sore

1.7

Patient Review

6/8/2017

Kenalog In Orabase for Canker Sore

This treatment barely did anything for me and made it hard to think clearly afterwards.

1.7

Patient Review

10/31/2022

Kenalog In Orabase for Canker Sore

I didn't notice any difference in pain relief or recovery time. The texture is also weird and hard to apply.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about kenalog in orabase

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Kenalog good for mouth ulcers?

"Kenalog in Orabase can help relieve the pain and discomfort of mouth ulcers, while speeding up the healing process."

Answered by AI

Does Kenalog in Orabase require a prescription?

"Kenalog in Orabase is not something that you become addicted to or form habits around. It can be prescribed by a doctor or recommended by a dentist or pharmacist to be bought at a pharmacy."

Answered by AI

What does Kenalog in Orabase do?

"This medication helps to temporarily relieve symptoms caused by mouth sores due to injury. The dental paste form of the medication allows it to stick to the inside of the mouth/cheeks/gums, and it works by reducing the swelling, itching, and pain that can occur with mouth sores."

Answered by AI

Is Kenalog in Orabase a steroid?

"Kenalog in Orabase® is a thick, sticky paste that contains a corticosteroid called triamcinolone acetonide. Corticosteroids are used to treat a wide range of different conditions by reducing inflammation, relieving itching and allergies."

Answered by AI