Hysingla Er

Acute Bronchitis, Pain, Chronic Pain + 10 more

Treatment

2 FDA approvals

10 Active Studies for Hysingla Er

What is Hysingla Er

Hydrocodone

The Generic name of this drug

Treatment Summary

Hydrocodone is an opioid drug derived from codeine and is commonly used to relieve moderate to severe pain. It was originally used as a cough suppressant, however, it has since been replaced by dextromethorphan. Hydrocodone's stronger metabolite, hydromorphone, is also used to treat severe pain. The FDA first approved hydrocodone in 1943 as part of the cough suppressant syrup Hycodan.

Hycodan

is the brand name

image of different drug pills on a surface

Hysingla Er Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Hycodan

Hydrocodone

1943

1122

Approved as Treatment by the FDA

Hydrocodone, otherwise called Hycodan, is approved by the FDA for 2 uses including Pain and Pain .

Pain

Used to treat Severe Pain in combination with Acetaminophen

Pain

Helps manage moderate Pain

Effectiveness

How Hysingla Er Affects Patients

Hydrocodone blocks pain signals in the brain and spine, which can create a feeling of euphoria, as well as making you feel sleepy and slowing your breathing.

How Hysingla Er works in the body

Hydrocodone works by attaching to the mu and delta opioid receptors in the body. This binding helps to block pain signals, stop neurotransmitter release, and prevent neurons from activating. It also can activate the reward and addiction pathway in the brain and cause sedation, respiratory depression, and suppression of the cough reflex. Hydrocodone attaches to the mu opioid receptor most strongly, but it also binds to the delta opioid receptor, which likely contributes to its pain-relieving effects.

When to interrupt dosage

The measure of Hysingla Er is dependent upon the identified malady, including Coughing, Coughing and Chronic Pain. The quantity of dosage can be found in the table below, based on the mode of delivery (e.g. Tablet, extended release - Oral or Tablet - Oral).

Condition

Dosage

Administration

Acute Bronchitis

7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Syrup - Oral, Syrup, Capsule, extended release, Capsule, extended release - Oral, Solution - Oral, Solution, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Tablet, extended release, Suspension, Suspension - Oral, Tablet, extended release - Oral, Liquid - Oral, Liquid, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral

Pain

7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Syrup - Oral, Syrup, Capsule, extended release, Capsule, extended release - Oral, Solution - Oral, Solution, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Tablet, extended release, Suspension, Suspension - Oral, Tablet, extended release - Oral, Liquid - Oral, Liquid, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral

Chronic Pain

7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Syrup - Oral, Syrup, Capsule, extended release, Capsule, extended release - Oral, Solution - Oral, Solution, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Tablet, extended release, Suspension, Suspension - Oral, Tablet, extended release - Oral, Liquid - Oral, Liquid, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral

Inflammation

7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Syrup - Oral, Syrup, Capsule, extended release, Capsule, extended release - Oral, Solution - Oral, Solution, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Tablet, extended release, Suspension, Suspension - Oral, Tablet, extended release - Oral, Liquid - Oral, Liquid, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral

Pain

7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Syrup - Oral, Syrup, Capsule, extended release, Capsule, extended release - Oral, Solution - Oral, Solution, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Tablet, extended release, Suspension, Suspension - Oral, Tablet, extended release - Oral, Liquid - Oral, Liquid, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral

Acute Pain

7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Syrup - Oral, Syrup, Capsule, extended release, Capsule, extended release - Oral, Solution - Oral, Solution, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Tablet, extended release, Suspension, Suspension - Oral, Tablet, extended release - Oral, Liquid - Oral, Liquid, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral

Rhinitis, Allergic

7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Syrup - Oral, Syrup, Capsule, extended release, Capsule, extended release - Oral, Solution - Oral, Solution, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Tablet, extended release, Suspension, Suspension - Oral, Tablet, extended release - Oral, Liquid - Oral, Liquid, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral

Rhinitis

7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Syrup - Oral, Syrup, Capsule, extended release, Capsule, extended release - Oral, Solution - Oral, Solution, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Tablet, extended release, Suspension, Suspension - Oral, Tablet, extended release - Oral, Liquid - Oral, Liquid, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral

Common Cold

7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Syrup - Oral, Syrup, Capsule, extended release, Capsule, extended release - Oral, Solution - Oral, Solution, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Tablet, extended release, Suspension, Suspension - Oral, Tablet, extended release - Oral, Liquid - Oral, Liquid, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral

Allergic rhinitis (disorder)

7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Syrup - Oral, Syrup, Capsule, extended release, Capsule, extended release - Oral, Solution - Oral, Solution, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Tablet, extended release, Suspension, Suspension - Oral, Tablet, extended release - Oral, Liquid - Oral, Liquid, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral

Coughing

7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Syrup - Oral, Syrup, Capsule, extended release, Capsule, extended release - Oral, Solution - Oral, Solution, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Tablet, extended release, Suspension, Suspension - Oral, Tablet, extended release - Oral, Liquid - Oral, Liquid, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral

Common Cold

7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Syrup - Oral, Syrup, Capsule, extended release, Capsule, extended release - Oral, Solution - Oral, Solution, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Tablet, extended release, Suspension, Suspension - Oral, Tablet, extended release - Oral, Liquid - Oral, Liquid, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral

Coughing

7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Syrup - Oral, Syrup, Capsule, extended release, Capsule, extended release - Oral, Solution - Oral, Solution, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Tablet, extended release, Suspension, Suspension - Oral, Tablet, extended release - Oral, Liquid - Oral, Liquid, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral

Warnings

Hysingla Er Contraindications

Condition

Risk Level

Notes

Intestinal Pseudo-Obstruction

Do Not Combine

Asthma

Do Not Combine

Intracranial Hypertension

Do Not Combine

Status Asthmaticus

Do Not Combine

Asthma

Do Not Combine

increased cerebrospinal pressure

Do Not Combine

Mental Depression

Do Not Combine

Pulmonary Heart Disease

Do Not Combine

Abdomen

Do Not Combine

Epilepsy

Do Not Combine

Pulmonary Disease, Chronic Obstructive

Do Not Combine

ethanol

Do Not Combine

Gastrointestinal obstruction

Do Not Combine

Alcohol Withdrawal Delirium

Do Not Combine

Asthma

Do Not Combine

Hypercarbia

Do Not Combine

Asthma

Do Not Combine

severe CNS depression

Do Not Combine

Pulse Frequency

Do Not Combine

Pulse Frequency

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Hydrocodone may interact with Pulse Frequency

There are 20 known major drug interactions with Hysingla Er.

Common Hysingla Er Drug Interactions

Drug Name

Risk Level

Description

Astemizole

Major

The metabolism of Astemizole can be decreased when combined with Hydrocodone.

Azelastine

Major

Hydrocodone may increase the central nervous system depressant (CNS depressant) activities of Azelastine.

Cyclophosphamide

Major

The metabolism of Cyclophosphamide can be decreased when combined with Hydrocodone.

Eluxadoline

Major

The risk or severity of constipation can be increased when Hydrocodone is combined with Eluxadoline.

Enasidenib

Major

The metabolism of Enasidenib can be decreased when combined with Hydrocodone.

Hysingla Er Toxicity & Overdose Risk

An overdose on hydrocodone can cause drowsiness, loss of muscle control, cold skin, small pupils, fluid buildup in the lungs, slow heart rate, low blood pressure, difficulty breathing, and in extreme cases death. It is important to ensure airways are open and provide assisted breathing if necessary. Treatments may include IV fluids, oxygen, and medications to increase blood pressure. If there are heart problems or cardiac arrest, advanced life support may be needed. Naloxone may be used to reverse the effects of the overdose, but should be done with caution as it can cause withdrawal symptoms in opioid tolerant patients. Emergency

image of a doctor in a lab doing drug, clinical research

Hysingla Er Novel Uses: Which Conditions Have a Clinical Trial Featuring Hysingla Er?

A total of 50 active studies are being conducted to analyze the efficacy of Hysingla ER in relieving Chronic Pain, Nasal Congestion caused by Common Cold and Acute Bronchitis.

Condition

Clinical Trials

Trial Phases

Acute Pain

1 Actively Recruiting

Not Applicable

Chronic Pain

0 Actively Recruiting

Pain

0 Actively Recruiting

Pain

0 Actively Recruiting

Rhinitis, Allergic

0 Actively Recruiting

Acute Bronchitis

7 Actively Recruiting

Phase 4, Not Applicable, Phase 3, Early Phase 1

Common Cold

0 Actively Recruiting

Allergic rhinitis (disorder)

0 Actively Recruiting

Rhinitis

0 Actively Recruiting

Inflammation

0 Actively Recruiting

Coughing

0 Actively Recruiting

Coughing

0 Actively Recruiting

Common Cold

0 Actively Recruiting

Hysingla Er Reviews: What are patients saying about Hysingla Er?

5

Patient Review

7/22/2017

Hysingla Er for Severe Pain

This drug has been phenomenal in terms of pain relief. I can now do dishes without having to take a three-hour break in between, and my feet have gone from being swollen all the time to almost normal. Thank you so much to the creators of this medication!

4.3

Patient Review

9/30/2022

Hysingla Er for Chronic Pain

So far, I'm really liking this medication. It's helped with my pain since I started taking it at 3pm today.

4.3

Patient Review

2/14/2018

Hysingla Er for Chronic Pain

I started at a low dose and gradually increased it until I found the right amount for me. Now, I only need to take something else for breakthrough pain on very rare occasions. This medication has made a huge impact in my quality of life by reducing my pain significantly.

4

Patient Review

8/17/2017

Hysingla Er for Chronic Pain

My pain management doctor put me on this medication because hydrocodone wasn't providing enough relief. I'm happy to report that my pain has decreased significantly and I can finally sleep through the night.

3.7

Patient Review

3/22/2018

Hysingla Er for Chronic Pain

My doctor prescribed Hysingla for me to take once daily, in addition to my hydrocodone for breakthrough pain. It worked great and I seldom needed extra hydrocodone; however, it is incredibly expensive. Over $400 for just 30 pills! I'll be going back to Norco.

2.7

Patient Review

9/28/2017

Hysingla Er for Chronic Pain

I was switched by my doctor from Morph ER to Hyslinga ER, and I'm in more pain now. The breakthru med is barely keeping it manageable. I'll have to wait a month to see the doctor again; not sure if he'll up the dosage or not.

2.7

Patient Review

10/24/2021

Hysingla Er for Severe Pain

The long-acting nature of this drug didn't work well for me because my pain is intermittent. Additionally, you can't take anything else for 12 hours after taking this which makes it difficult to manage.

2.7

Patient Review

12/3/2018

Hysingla Er for Chronic Pain

I didn't find this medication to work very well, and it also felt like it was hard on my organs. I would much rather take a pain medication three times a day if it meant better relief.

2

Patient Review

9/18/2017

Hysingla Er for Chronic Pain

I didn't find this medication to be effective at lower doses, and higher doses only provided relief after a couple of hours. For me, it wasn't any better than taking pain medication multiple times per day. Additionally, it actually caused pain in areas where I previously had no pain!

2

Patient Review

3/1/2018

Hysingla Er for Severe Pain

I've been in severe pain for the past three months since I switched from morphine to this medication. From what I've read, it sounds like other people have had more luck with higher doses. Here's hoping my doctor will up my dosage so I can finally get some relief.

2

Patient Review

12/20/2019

Hysingla Er for Chronic Pain

I was switched from Embeda to Hysingla by my doctor, and within 48 hours started having extremely high blood pressure and most of the other symptoms associated with withdrawal. My pain doctor says that this isn't withdrawal from just switching medications, but he's not the one writhing in pain for days on end. The system is totally ridiculous.

2

Patient Review

8/31/2022

Hysingla Er for severe chronic pain requiring long-term opioid treatment

I didn't feel any difference the first time I took it, and the second night was really bad. It felt like my feet were on fire. My doctor said to give it 7-10 days, but after 13 days I couldn't take it anymore. The pain was too much.

1.7

Patient Review

3/2/2018

Hysingla Er for Chronic Pain

The pain relief from this medication is only moderate and it doesn't last very long. I would rather take other medications that are more effective.

1.7

Patient Review

5/28/2018

Hysingla Er for Severe Pain

I am currently taking hydro 10/325 and hyslinger 30. I'm curious about what the difference is between the two dosages, and if it is safe to take hyslinger 30.

1.7

Patient Review

9/13/2019

Hysingla Er for Chronic Pain

It takes a while for this medication to take effect; however, it does provide some relief from pain. I cried for 18 hours because my doctor didn't believe me about the intensity of my pain.

1

Patient Review

12/12/2018

Hysingla Er for Chronic Pain

In my experience, this medication was totally unreliable for pain relief. I had to use just as many IR breakthrough meds as before. Additionally, it's action was unpredictable; I once passed out in the middle of the day the day AFTER taking it. Not to mention, it is extremely difficult to swallow and very costly: $500 for a month's supply. All of these factors add up to a completely useless and expensive medication that does more harm than good.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about hysingla er

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does Hysingla ER have acetaminophen in it?

"Hysingla ER does not contain acetaminophen and therefore does not put users at risk for liver toxicity like other hydrocodone products that do contain acetaminophen."

Answered by AI

How often do you take Hysingla?

"HYSINGLA ER should be taken once a day, every 24 hours. The tablet should be swallowed whole with enough water to ensure it is fully swallowed."

Answered by AI

What are the side effects of Hysingla ER?

"The most common adverse reactions reported by patients treated with Hysingla ER in the chronic pain clinical trials were constipation, nausea, vomiting, fatigue, upper respiratory tract infection, dizziness, headache, and somnolence."

Answered by AI

Clinical Trials for Hysingla Er

Image of AltaSciences, Inc in Cypress, United States.

SBS-147 Safety Study

18 - 55
All Sexes
Cypress, CA

This study is part of the HEAL Initiative supported by the NIH. The purpose of this study is to learn how safe the study drug, SBS-147, is and how people's bodies respond to and process it. Researchers will also look for any side effects that may occur when taking SBS-147. Some participants will receive SBS-147, and others will receive a placebo, which looks the same but does not contain any medicine. This helps researchers fairly compare results. The study includes two parts: Single-Dose Group, where Participants receive SBS-147 or placebo one time. Multiple-Dose Group, where Participants receive SBS-147 or placebo once or twice daily for 7 days.

Phase 1
Waitlist Available

AltaSciences, Inc

Jeff Reich, MD

Sparian Biosciences, Inc

Image of University of California San Diego in San Deigo, United States.

Omeprazole + Lifestyle Therapy for Laryngopharyngeal Reflux

18 - 89
All Sexes
San Deigo, CA

The goal of this clinical trial is to learn if a mechanism guided strategy that utilizes a multidisciplinary approach to treat adults patients (age 18-89) with chronic throat symptoms who are undergoing clinical evaluation for laryngopharyngeal reflux (LPR) is more effective than the usual care strategy with proton pump inhibitor (PPI) therapy used in gastroenterology for these patients. The main question it aims to answer is: Will a greater proportion of the mechanism guided strategy participants achieve symptom response in comparison to the usual care strategy participants? If there is a comparison group: Researchers will compare the mechanism guided strategy to usual care strategy to see if treatment response differs between the groups. Participants will be be asked to do the following: * participate in an 8-week blinded study phase where they will be randomized to either 1) Mechanism Guided Strategy or 2) Usual Care Strategy * take an oral capsule daily (omeprazole 40mg or placebo) * come to 3 in-person visits at UC San Diego Health for an intervention visit with a study provider * consider incorporating recommended lifestyle modifications * complete weekly surveys

Phase 4
Recruiting

University of California San Diego

Rena Yadlapati, MD

Image of Medical University of South Carolina in Charleston, United States.

Steroid Injection for Chronic Cough

18+
All Sexes
Charleston, SC

The primary goal of this study is to test the hypothesis that injecting steroid intramuscularly is an effective treatment for unexplained chronic cough. This will be achieved through the design of a prospective, placebo-controlled, single-blind, randomized clinical trial in which one group of patients will undergo a steroid injection into the deltoid muscle and the second group will undergo a placebo injection into the deltoid muscle. Data to determine if a clinically significant difference exists between the outcomes of the two groups will be measured by a dichotomous yes/no response to improvement, the Leicester Cough Questionnaire, and a visual analogue scale for symptom severity. This will provide the answer to the general question of whether or not the intramuscular injections are clinically effective for patients with unexplained chronic cough. Furthermore, any adverse reactions will be thoroughly documented. If this hypothesized treatment is proven effective, this can greatly improve the care of chronic cough patients by allowing for an evidence-based treatment option and a treatment option that may improve access to care. While the superior laryngeal nerve (SLN) injection is typically performed by fellowship trained laryngologists, intramuscular injections could be more widely utilized by general otolaryngologists or providers in other fields of medicine.

Phase < 1
Recruiting

Medical University of South Carolina

Lauren Howser

Have you considered Hysingla Er clinical trials?

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Have you considered Hysingla Er clinical trials?

We made a collection of clinical trials featuring Hysingla Er, we think they might fit your search criteria.
Go to Trials