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What is Hysingla Er
HydrocodoneThe Generic name of this drug
Treatment SummaryHydrocodone is an opioid drug derived from codeine and is commonly used to relieve moderate to severe pain. It was originally used as a cough suppressant, however, it has since been replaced by dextromethorphan. Hydrocodone's stronger metabolite, hydromorphone, is also used to treat severe pain. The FDA first approved hydrocodone in 1943 as part of the cough suppressant syrup Hycodan.
Hycodanis the brand name
Hysingla Er Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Hycodan
Hydrocodone
1943
1122
Approved as Treatment by the FDA
Hydrocodone, otherwise called Hycodan, is approved by the FDA for 2 uses including Pain and Pain .Pain
Used to treat Severe Pain in combination with Acetaminophen
Pain
Helps manage moderate Pain
Effectiveness
How Hysingla Er Affects PatientsHydrocodone blocks pain signals in the brain and spine, which can create a feeling of euphoria, as well as making you feel sleepy and slowing your breathing.
How Hysingla Er works in the bodyHydrocodone works by attaching to the mu and delta opioid receptors in the body. This binding helps to block pain signals, stop neurotransmitter release, and prevent neurons from activating. It also can activate the reward and addiction pathway in the brain and cause sedation, respiratory depression, and suppression of the cough reflex. Hydrocodone attaches to the mu opioid receptor most strongly, but it also binds to the delta opioid receptor, which likely contributes to its pain-relieving effects.
When to interrupt dosage
The measure of Hysingla Er is dependent upon the identified malady, including Coughing, Coughing and Chronic Pain. The quantity of dosage can be found in the table below, based on the mode of delivery (e.g. Tablet, extended release - Oral or Tablet - Oral).Condition
Dosage
Administration
Rhinitis
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Coughing
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Inflammation
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Coughing
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Chronic Pain
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Acute Bronchitis
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Pain
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
upper respiratory symptoms caused by Common Cold
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Allergic rhinitis (disorder)
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Nasal Congestion caused by Common Cold
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Nasal Congestion caused by Allergic Rhinitis
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Pain
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Acute Pain
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Warnings
Hysingla Er ContraindicationsCondition
Risk Level
Notes
Paralytic Ileus
Do Not Combine
Asthma
Do Not Combine
Intracranial Hypertension
Do Not Combine
Status Asthmaticus
Do Not Combine
in the absence of resuscitative equipment acute bronchial asthma
Do Not Combine
increased cerebrospinal pressure
Do Not Combine
Mental Depression
Do Not Combine
Cor Pulmonale
Do Not Combine
Abdomen
Do Not Combine
convulsive disorders
Do Not Combine
chronic obstructive airway
Do Not Combine
ethanol
Do Not Combine
Gastrointestinal obstruction
Do Not Combine
Alcohol Withdrawal Delirium
Do Not Combine
Asthma
Do Not Combine
Hypercarbia
Do Not Combine
Asthma
Do Not Combine
severe CNS depression
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Hydrocodone may interact with Pulse Frequency
Common Hysingla Er Drug Interactions
Drug Name
Risk Level
Description
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Hydrocodone.
Azelastine
Major
Hydrocodone may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Cyclophosphamide
Major
The metabolism of Cyclophosphamide can be decreased when combined with Hydrocodone.
Eluxadoline
Major
The risk or severity of constipation can be increased when Hydrocodone is combined with Eluxadoline.
Enasidenib
Major
The metabolism of Enasidenib can be decreased when combined with Hydrocodone.
Hysingla Er Toxicity & Overdose RiskAn overdose on hydrocodone can cause drowsiness, loss of muscle control, cold skin, small pupils, fluid buildup in the lungs, slow heart rate, low blood pressure, difficulty breathing, and in extreme cases death. It is important to ensure airways are open and provide assisted breathing if necessary. Treatments may include IV fluids, oxygen, and medications to increase blood pressure. If there are heart problems or cardiac arrest, advanced life support may be needed. Naloxone may be used to reverse the effects of the overdose, but should be done with caution as it can cause withdrawal symptoms in opioid tolerant patients. Emergency
Hysingla Er Novel Uses: Which Conditions Have a Clinical Trial Featuring Hysingla Er?
A total of 50 active studies are being conducted to analyze the efficacy of Hysingla ER in relieving Chronic Pain, Nasal Congestion caused by Common Cold and Acute Bronchitis.Condition
Clinical Trials
Trial Phases
Chronic Pain
31 Actively Recruiting
Phase 2, Not Applicable, Phase 3
Coughing
0 Actively Recruiting
Acute Bronchitis
12 Actively Recruiting
Phase 4, Not Applicable, Phase 2, Phase 3, Phase 1
Allergic rhinitis (disorder)
0 Actively Recruiting
Pain
0 Actively Recruiting
Pain
0 Actively Recruiting
Rhinitis
0 Actively Recruiting
Nasal Congestion caused by Allergic Rhinitis
0 Actively Recruiting
Coughing
0 Actively Recruiting
upper respiratory symptoms caused by Common Cold
0 Actively Recruiting
Nasal Congestion caused by Common Cold
0 Actively Recruiting
Inflammation
0 Actively Recruiting
Acute Pain
21 Actively Recruiting
Early Phase 1, Not Applicable, Phase 4, Phase 2, Phase 1
Hysingla Er Reviews: What are patients saying about Hysingla Er?
5Patient Review
7/22/2017 This drug has been phenomenal in terms of pain relief. I can now do dishes without having to take a three-hour break in between, and my feet have gone from being swollen all the time to almost normal. Thank you so much to the creators of this medication!
4.3Patient Review
9/30/2022 So far, I'm really liking this medication. It's helped with my pain since I started taking it at 3pm today.
4.3Patient Review
2/14/2018 I started at a low dose and gradually increased it until I found the right amount for me. Now, I only need to take something else for breakthrough pain on very rare occasions. This medication has made a huge impact in my quality of life by reducing my pain significantly.
4Patient Review
8/17/2017 My pain management doctor put me on this medication because hydrocodone wasn't providing enough relief. I'm happy to report that my pain has decreased significantly and I can finally sleep through the night.
3.7Patient Review
3/22/2018 My doctor prescribed Hysingla for me to take once daily, in addition to my hydrocodone for breakthrough pain. It worked great and I seldom needed extra hydrocodone; however, it is incredibly expensive. Over $400 for just 30 pills! I'll be going back to Norco.
2.7Patient Review
9/28/2017 I was switched by my doctor from Morph ER to Hyslinga ER, and I'm in more pain now. The breakthru med is barely keeping it manageable. I'll have to wait a month to see the doctor again; not sure if he'll up the dosage or not.
2.7Patient Review
10/24/2021 The long-acting nature of this drug didn't work well for me because my pain is intermittent. Additionally, you can't take anything else for 12 hours after taking this which makes it difficult to manage.
2.7Patient Review
12/3/2018 I didn't find this medication to work very well, and it also felt like it was hard on my organs. I would much rather take a pain medication three times a day if it meant better relief.
2Patient Review
9/18/2017 I didn't find this medication to be effective at lower doses, and higher doses only provided relief after a couple of hours. For me, it wasn't any better than taking pain medication multiple times per day. Additionally, it actually caused pain in areas where I previously had no pain!
2Patient Review
3/1/2018 I've been in severe pain for the past three months since I switched from morphine to this medication. From what I've read, it sounds like other people have had more luck with higher doses. Here's hoping my doctor will up my dosage so I can finally get some relief.
2Patient Review
12/20/2019 I was switched from Embeda to Hysingla by my doctor, and within 48 hours started having extremely high blood pressure and most of the other symptoms associated with withdrawal. My pain doctor says that this isn't withdrawal from just switching medications, but he's not the one writhing in pain for days on end. The system is totally ridiculous.
2Patient Review
8/31/2022 I didn't feel any difference the first time I took it, and the second night was really bad. It felt like my feet were on fire. My doctor said to give it 7-10 days, but after 13 days I couldn't take it anymore. The pain was too much.
1.7Patient Review
3/2/2018 The pain relief from this medication is only moderate and it doesn't last very long. I would rather take other medications that are more effective.
1.7Patient Review
5/28/2018 I am currently taking hydro 10/325 and hyslinger 30. I'm curious about what the difference is between the two dosages, and if it is safe to take hyslinger 30.
1.7Patient Review
9/13/2019 It takes a while for this medication to take effect; however, it does provide some relief from pain. I cried for 18 hours because my doctor didn't believe me about the intensity of my pain.
1Patient Review
12/12/2018 In my experience, this medication was totally unreliable for pain relief. I had to use just as many IR breakthrough meds as before. Additionally, it's action was unpredictable; I once passed out in the middle of the day the day AFTER taking it. Not to mention, it is extremely difficult to swallow and very costly: $500 for a month's supply. All of these factors add up to a completely useless and expensive medication that does more harm than good.
Patient Q&A Section about hysingla er
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Does Hysingla ER have acetaminophen in it?
"Hysingla ER does not contain acetaminophen and therefore does not put users at risk for liver toxicity like other hydrocodone products that do contain acetaminophen."
Answered by AI
How often do you take Hysingla?
"HYSINGLA ER should be taken once a day, every 24 hours. The tablet should be swallowed whole with enough water to ensure it is fully swallowed."
Answered by AI
What are the side effects of Hysingla ER?
"The most common adverse reactions reported by patients treated with Hysingla ER in the chronic pain clinical trials were constipation, nausea, vomiting, fatigue, upper respiratory tract infection, dizziness, headache, and somnolence."
Answered by AI