Hydrocortisone Acetate

Scleritis, Iridocyclitis, Iritis + 47 more

Treatment

22 FDA approvals

20 Active Studies for Hydrocortisone Acetate

What is Hydrocortisone Acetate

Hydrocortisone acetate

The Generic name of this drug

Cortisporin

is the brand name

Hydrocortisone Acetate Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Cortisporin

Hydrocortisone acetate

1963

43

Approved as Treatment by the FDA

Hydrocortisone acetate, commonly known as Cortisporin, is approved by the FDA for 22 uses which include Hypersensitivity and Neoplastic Disease .

Hypersensitivity

Neoplastic Disease

Collagen Diseases

Rheumatoid Arthritis

Helps manage Rheumatoid Arthritis

Skin Diseases

Androgenital syndrome

Helps manage Androgenital syndrome

Haemorrhoids

Thyroiditis

Helps manage Thyroiditis

Thyroiditis

Helps manage Thyroiditis

Dermatological Disease

Itching

Ulcerative Colitis

Used in combination with other therapies

Pruritus

hormonal disorder

Proctitis

Helps manage Proctitis

Atopic Dermatitis

Skin Irritation

Adrenal Insufficiency

Helps manage Adrenal cortical hypofunctions

Ulcerative Colitis

Used in combination with other therapies

Adrenal cortical hypofunctions

Helps manage Adrenal cortical hypofunctions

Proctitis

Helps manage Proctitis

cryptitis

Helps manage cryptitis

Effectiveness

How Hydrocortisone Acetate Affects Patients

Hydrocortisone is a steroid hormone that is essential for life, and can help regulate and support many important functions in the body. Topically applied hydrocortisone is used to reduce inflammation due to certain skin conditions. Glucocorticoids, like hydrocortisone, are a type of steroid hormone that can bind to cortisol receptors and trigger various effects. Glucocorticoids reduce cell-mediated immunity by lowering the amount of cytokines produced, and also decrease humoral immunity by reducing the amount of B cells. This results in fewer T lymphocyte cells being activated.

How Hydrocortisone Acetate works in the body

Hydrocortisone works to reduce inflammation by stopping the production of two main inflammatory molecules, prostaglandins and leukotrienes. It does this by blocking a phospholipase enzyme from coming into contact with its substrate, arachidonic acid. It also decreases the expression of two enzymes that help produce these molecules, COX-1 and COX-2. Hydrocortisone also suppresses the immune system by reducing the function of the lymphatic system, decreasing immunoglobulins and complement concentrations, and interfering with the binding of antigens and antibodies.

When to interrupt dosage

The amount of Hydrocortisone Acetate is contingent upon the diagnosed condition, including Pink Eye, Skin Infections and hormonal disorder. The amount of dosage differs, in relation to the administration process laid out in the table beneath.

Condition

Dosage

Administration

Acute, Inflammatory Superficial Cutaneous Lesions caused by susceptible bacteria

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Thyroiditis

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Itching

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Blepharitis

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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ocular bacterial infections

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Adrenal Insufficiency

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Communicable Diseases

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Adrenal Cortex Hormones

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Collagen Diseases

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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hormonal disorder

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Ulcerative Colitis

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Anorectal Surgeries

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Fissure in Ano

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Anal inflammation

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Proctitis

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Postoperative

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Allergic Conjunctivitis (AC)

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Dermatitis

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

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Hemorrhoids

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

Topical, , Aerosol, foam, Aerosol, foam - Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Ointment, Ointment - Topical, Kit, Suppository - Rectal, Rectal, Suppository, Cream - Rectal, Gel - Rectal, Gel, Gel - Topical, Aerosol, foam - Rectal, Auricular (otic); Ophthalmic, Ointment - Auricular (otic); Ophthalmic, Suspension - Auricular (otic); Ophthalmic, Suspension, Rectal; Topical, Ointment - Rectal; Topical, Ointment - Rectal, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Aerosol, Aerosol - Rectal, Soap, Soap - Topical, Powder - Topical, Powder, for solution - Topical, Powder, for solution, Powder, Cream - Rectal; Topical, Lotion / shampoo, Lotion / shampoo - Topical, Ointment - Ophthalmic, Shampoo - Topical, Shampoo, Kit - Topical, Solution, Solution - Topical, Auricular (otic), Solution / drops - Auricular (otic), Suspension - Ophthalmic, Suspension - Auricular (otic), Kit - Oral, Oral, Kit - Irrigation; Ophthalmic; Topical, Irrigation; Ophthalmic; Topical, Kit - Irrigation; Ophthalmic; Respiratory (inhalation); Topical, Oral; Rectal, Kit - Ophthalmic; Respiratory (inhalation); Topical, Ophthalmic; Topical, Kit - Respiratory (inhalation); Topical, Kit - Ophthalmic; Topical, Ophthalmic; Respiratory (inhalation); Topical, Irrigation; Ophthalmic; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Oral; Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Respiratory (inhalation); Topical

Androgenital syndrome

, 0.01 mg/mg, 0.15 mg/mg, 20.0 mg/mL, 0.025 mg/mg, 25.0 mg/mL, 10.0 mg/mL, 25.0 mg, 30.0 mg, 0.005 mg/mg, 0.02 mg/mg, 0.0088 mL/mL, 100.0 mg/mL, 0.0185 mg/mg, 0.019 mg/mg, 0.0055 mg/mg, 0.0112 mg/mg, 5.0 mg/mL, 0.5 %, 10.0 mg, 1.0 %, 40.0 mg, 1.5 %, 0.028 mg/mg, 1.0 mg/mg, 5.0 mg, 2.0 %, 2.5 %, 10.0 %, 23.5 mg/mL, 18.5 mg/mL, 0.9 mg/mg, 15.0 mg/mL, 0.0705 mg/mg, 0.25 mg/mg, 0.001 mg/mg, 11.2 mg/mL, 0.04 mg/mg, 0.0235 mg/mg, 0.0075 mg/mg

Topical, , Aerosol, foam, Aerosol, foam - Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Ointment, Ointment - Topical, Kit, Suppository - Rectal, Rectal, Suppository, Cream - Rectal, Gel - Rectal, Gel, Gel - Topical, Aerosol, foam - Rectal, Auricular (otic); Ophthalmic, Ointment - Auricular (otic); Ophthalmic, Suspension - Auricular (otic); Ophthalmic, Suspension, Rectal; Topical, Ointment - Rectal; Topical, Ointment - Rectal, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Aerosol, Aerosol - Rectal, Soap, Soap - Topical, Powder - Topical, Powder, for solution - Topical, Powder, for solution, Powder, Cream - Rectal; Topical, Lotion / shampoo, Lotion / shampoo - Topical, Ointment - Ophthalmic, Shampoo - Topical, Shampoo, Kit - Topical, Solution, Solution - Topical, Auricular (otic), Solution / drops - Auricular (otic), Suspension - Ophthalmic, Suspension - Auricular (otic), Kit - Oral, Oral, Kit - Irrigation; Ophthalmic; Topical, Irrigation; Ophthalmic; Topical, Kit - Irrigation; Ophthalmic; Respiratory (inhalation); Topical, Oral; Rectal, Kit - Ophthalmic; Respiratory (inhalation); Topical, Ophthalmic; Topical, Kit - Respiratory (inhalation); Topical, Kit - Ophthalmic; Topical, Ophthalmic; Respiratory (inhalation); Topical, Irrigation; Ophthalmic; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Oral; Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Respiratory (inhalation); Topical

Warnings

There are 20 known major drug interactions with Hydrocortisone Acetate.

Common Hydrocortisone Acetate Drug Interactions

Drug Name

Risk Level

Description

Abemaciclib

Major

The metabolism of Abemaciclib can be increased when combined with Hydrocortisone acetate.

Acalabrutinib

Major

The metabolism of Acalabrutinib can be increased when combined with Hydrocortisone acetate.

Alectinib

Major

The metabolism of Alectinib can be increased when combined with Hydrocortisone acetate.

Alpelisib

Major

The metabolism of Alpelisib can be increased when combined with Hydrocortisone acetate.

Aminophylline

Major

The metabolism of Aminophylline can be increased when combined with Hydrocortisone acetate.

Hydrocortisone Acetate Toxicity & Overdose Risk

Side effects of this drug include reduced bone growth, decreased calcium absorption, and slower wound healing.

Hydrocortisone Acetate Novel Uses: Which Conditions Have a Clinical Trial Featuring Hydrocortisone Acetate?

Presently, 91 active studies are examining the potential of Hydrocortisone Acetate to alleviate cryptitis, Eye Inflammation and Dermatitis.

Condition

Clinical Trials

Trial Phases

Rheumatoid Arthritis

55 Actively Recruiting

Not Applicable, Phase 4, Phase 3, Phase 2, Phase 1

Open-angle glaucoma

45 Actively Recruiting

Not Applicable, Phase 2, Phase 3, Phase 4, Early Phase 1, Phase 1

Thyroiditis

0 Actively Recruiting

Adrenal Insufficiency

0 Actively Recruiting

Fluorophotometry

0 Actively Recruiting

Eczema

0 Actively Recruiting

Ulcerative Colitis

14 Actively Recruiting

Phase 3, Phase 2, Not Applicable, Phase 4, Phase 1

Anorectal Surgeries

0 Actively Recruiting

Defecation

0 Actively Recruiting

Iritis

0 Actively Recruiting

Proctitis

0 Actively Recruiting

Hypersensitivity

1 Actively Recruiting

Phase 4

Allergic Conjunctivitis (AC)

1 Actively Recruiting

Phase 2

Dermatologic disorders

0 Actively Recruiting

Scleritis

0 Actively Recruiting

Communicable Diseases

0 Actively Recruiting

Androgenital syndrome

0 Actively Recruiting

Haemorrhoids

1 Actively Recruiting

Not Applicable

Neoplastic Disease

1 Actively Recruiting

Phase 1

Dermatitis

1 Actively Recruiting

Not Applicable

Hydrocortisone Acetate Reviews: What are patients saying about Hydrocortisone Acetate?

4.7

Patient Review

3/6/2021

Hydrocortisone Acetate for Atopic Dermatitis

I've been struggling with eczema for a while, but it reached a fever-pitch recently. After using this treatment prescribed by my doctor, the swelling went down significantly. I'm happy to report that after continued use, my symptoms have all but disappeared.

3

Patient Review

8/2/2020

Hydrocortisone Acetate for Skin Condition

This medication is very effective at healing ulcers.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about hydrocortisone acetate

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How long does it take hydrocortisone acetate to work?

"The symptoms of proctitis may improve within 5 to 7 days."

Answered by AI

What is hydrocortisone acetate used for?

"Hydrocortisone acetate reduces swelling, itching, and redness associated with various skin conditions. It is a mild corticosteroid."

Answered by AI

What's the difference between hydrocortisone and hydrocortisone acetate?

"One-hundred twelve milligrams of hydrocortisone acetate is similar to 100 mg of hydrocortisone. One-hundred nineteen milligrams of hydrocortisone butyrate is also similar to 100 mg of hydrocortisone."

Answered by AI

Is Hydrocortisone Acetate a prescription?

"Hydrocortisone Acetate is the active ingredient in a number of prescription and over-the-counter topical medicines that treat inflammation. It is available as an ointment, cream, or suppository."

Answered by AI

Clinical Trials for Hydrocortisone Acetate

Image of University Center for Ambulatory Surgery in Somerset, United States.

Infusion Pump for Postoperative Pain

18+
All Sexes
Somerset, NJ

This study will be a pragmatic, prospective cluster randomized trial, where clusters will formed based on sequential 2 week time increments across the study recruitment period.. Patients 18 years or older undergoing ACL reconstruction, open shoulder labrum or rotator cuff surgery, arthroscopic rotator cuff repair, proximal or distal patellar realignment surgery, open knee arthrotomy cases (i.e. inside out meniscus repair, osteochondral allograft transplantation (OCA), meniscal allograft transplantation (MAT)) at University Center for Ambulatory Surgery, LLC (UOA) will be reviewed for eligibility. Once identified, potential study subjects will be asked whether they are interested in participating in the project. If the patient agrees, the subject will be given the informed consent to read and sign. Objectives: The primary objective is to compare the effectiveness of postoperative infusion pain pump versus preoperative nerve block in reducing visual analog pain scores/numerical pain rating scale (VAS/NPRS) in the postoperative period. The second objective is to evaluate the requirement of narcotic and non-narcotic analgesic medications between the two groups. Hypotheses: Use of continuous infusion pain pump or single shot peripheral block will result in similar post-operative pain control after outpatient sports medicine surgical cases.

Phase 4
Recruiting

University Center for Ambulatory Surgery

Image of University of Waterloo, School of Optometry and Vision Science in Waterloo, Canada.

Brain Stimulation for Vision Impairment

18+
All Sexes
Waterloo, Canada

This pilot clinical trial evaluates whether non-invasive brain stimulation improves the orientation and mobility (O\&M) skills of individuals with constricted visual fields in both eyes. The study is composed of three visits. The first visit is meant to confirm eligibility by performing a few clinical tests. Eligible participants will then complete two additional visits, one in which they receive active stimulation, and one in which they receive placebo (sham) stimulation. Stimulation will be administered in a randomized, double-blind order. To evaluate improvement, various measures of O\&M performance will be assessed on a standardized obstacle course featuring static natural and artificial obstacles at defined intervals after the intervention. We hypothesize that the application of brain stimulation to region of the brain responsible for visual processing will improve the orientation and mobility skills of individuals with binocular constricted visual fields immediately following stimulation, and the results will inform the design of a future, larger-scale study.

Waitlist Available
Device

University of Waterloo, School of Optometry and Vision Science

Benjamin Thompson, PhD

Image of McMaster Children's Hospital - Digestive Diseases Clinic in Hamilton, Canada.

Vancomycin for Ulcerative Colitis

18+
All Sexes
Hamilton, Canada

This clinical trial tests if oral vancomycin can safely treat active ulcerative colitis (UC) in adults who also have primary sclerosing cholangitis (PSC), a liver condition. The main questions it aims to answer are: * Can oral vancomycin improve UC symptoms as measured by Mayo score at 4 weeks? * Is oral vancomycin safe and tolerable in this patient group? Participants will be compared to see if vancomycin works better than placebo. Participants will: * Take oral vancomycin (250 mg twice daily) or identical placebo capsules for 4 weeks * Have the option for 4 more weeks of open-label vancomycin after the blinded phase * Attend clinic visits at baseline, week 4, and follow-up for Mayo scoring, endoscopy, blood/stool tests, and safety checks * Track treatment adherence and side effects The study primarily assesses if the trial can recruit 14 participants, retain them, achieve good adherence, and follow protocol procedures (feasibility). Secondary goals include safety (adverse events) and early signs of benefit in UC activity, liver tests, and gut bacteria balance. This pilot will guide larger future studies.

Phase 2
Waitlist Available

McMaster Children's Hospital - Digestive Diseases Clinic

Neeraj Narula, MD

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Image of Johns Hopkins Bayview Medical Center in Baltimore, United States.

VR-Enhanced PMR for Post-Burn Symptoms

18+
All Sexes
Baltimore, MD

The goal of this clinical trial is to learn whether progressive muscle relaxation (PMR), delivered either alone or enhanced with virtual reality (VR), can help treat chronic symptom, such as pain, itch, anxiety, sleep disturbances, and fatigue, in adult burn survivors. The main questions it aims to answer are: * Does VR-enhanced PMR (VR-PMR) reduce chronic pain, anxiety, itch, sleep disturbances, and fatigue more effectively than standard PMR? * Is VR-PMR a feasible and acceptable self-administered home-based intervention for burn survivors? Researchers will compare two self-administered intervention conditions, VR-enhanced PMR and standard PMR, using a randomized to sequence crossover design to see if VR technology enhances the therapeutic effects of PMR on chronic symptom management in burn survivors. Participants will: * Complete home-based sessions of VR-enhanced PMR * Complete home-based sessions of standard PMR * Report symptoms such as pain, itch, anxiety, sleep disturbances, and fatigue throughout the study * Use VR equipment provided for the intervention period (during the VR-PMR arm)

Recruiting
Has No Placebo

Johns Hopkins Bayview Medical Center

Sheera Lerman Zohar, PhD

Image of MUHC - Montreal General Hospital in Montreal, Canada.

Ustekinumab for Crohn's Disease and Ulcerative Colitis

18+
All Sexes
Montreal, Canada

The goal of this clinical trial is to evaluate whether disease remission can be maintained when biologic therapy is reduced in patients with Crohn"s disease (CD) and ulcerative colitis (UC) taking ustekinumab (UST). The main question it aims to answer is: Can we de-escalate UST subcutaneous dose either from every 4 weeks (Q4) to every 8 weeks (Q8) or every 8 weeks (Q8) to every 12 weeks (Q12) in CD or UC patients in deep remission without loosing their response? Researchers will follow UST blood levels, inflammation markers and intestinal mucosa integrity and to see if UST dose can be reduced while maintaining clinical remission. Participants will: Change UST dosing from Q4 to Q8 or from Q8 to Q12. Visit the clinic once every 12 weeks for checkups and tests.

Phase 4
Recruiting

MUHC - Montreal General Hospital

Janssen Inc.

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Image of The Royal Alexandra Hospital in Edmonton, Canada.

Graft Selection for Glaucoma Surgery

18 - 110
All Sexes
Edmonton, Canada

Glaucoma refers to a group of progressive optic neuropathies that lead to permanent vision loss. Glaucoma is the leading cause of irreversible blindness globally. In 2020, it was estimated to affect 76 million individuals worldwide, with projections indicating this number will rise to 111.8 million by 2040. In Canada, glaucoma affects an estimated 2.7-7.5% of individuals over the age of 50, contributing substantially to the national disease burden. This condition is linked to damage of the optic nerve due to elevated intraocular pressure (IOP; raised eye pressure), which results in the loss of retinal ganglion cells. Therefore, most of the treatments are guided towards reducing the IOP either via using laser, medications or surgery. Glaucoma surgery is typically reserved for cases where IOP remains uncontrolled while on maximum tolerated medical therapy and/or where glaucoma progression warrants surgery. The goal of many glaucoma surgeries is to divert aqueous humor from the anterior chamber to the subconjunctival space, therefore reducing intraocular pressure. The device used for this purpose are the PRESERFLO™ MicroShunt (Glaukos Corporation, Laguna Hills, CA, USA) (the documents will interchangeably use terms "stent" and "shunt" to refer to these devices in the text below). The device is implanted using the ab externo approach to channel fluid from the anterior chamber to the subconjunctival/subtenon space. To reduce postoperative fibrosis and inhibit fibroblast activity that could obstruct flow and lead to device failure, 5-fluorouracil (5-FU) or mitomycin C (MMC) are administered. Additionally, a double-layered closure of conjunctiva and Tenon's is performed to minimize Tenon's migration and blockage of tenon the stents. Despite these measures, stent encapsulation and failure are still too common requiring revisions and bleb needling in 2-20% of cases within the first 12 months of follow-up. This project will involve a series of studies evaluating graft selection in PreserFlo MicroShunt implantation, focusing on donor sclera, cornea, and pericardium as patch graft materials. First, the investigators will conduct a prospective, randomized study comparing clinical outcomes between these graft types. Outcomes of interest will include surgical success rates, post-operative hypotony, tube erosion, conjunctival complications, infection, and overall device longevity. Donor sclera has long been used as a patch graft in glaucoma drainage device surgery and is associated with low erosion rates and reliable long-term results. Corneal tissue is increasingly used due to its transparency and availability through eye banks, with demonstrated safety in ocular surface reconstruction and tube coverage. Pericardium is another durable, biocompatible option, historically applied in both cardiovascular and ocular surgery, and has shown effectiveness as a patch graft in glaucoma drainage implants. This comparison will extend to both primary implantation and revision surgeries, recognizing the high clinical relevance of graft performance in complex cases. Building on these results, the investigators will then perform a cost-effectiveness analysis of graft strategies, incorporating surgical time, post-operative management, complication rates, and need for re-operation. An economic model will be developed to evaluate costs and resource utilization associated with each material, providing valuable data for policy and surgical decision-making. Finally, the investigators will conduct a patient-reported outcome (PRO) study to assess patient comfort and satisfaction with different grafts. Surveys will evaluate domains such as foreign body sensation, cosmesis, and overall satisfaction at key time points (immediate post-operative period, 1 week, 3 weeks, and 3 months). These results will highlight the patient perspective, an often underrepresented but critical factor in surgical innovation. Together, these studies will comprehensively assess graft selection from surgical, economic, and patient-centered perspectives, informing evidence-based practice in glaucoma care.

Waitlist Available
Has No Placebo

The Royal Alexandra Hospital

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