Hycodan

Acute Bronchitis, Pain, Chronic Pain + 10 more
Treatment
2 FDA approvals
7 Active Studies for Hycodan

What is Hycodan

HydrocodoneThe Generic name of this drug
Treatment SummaryHydrocodone is an opioid medication used to relieve moderate to severe pain. It is often combined with acetaminophen for better pain relief. In the past, hydrocodone was used as a cough suppressant, but it has been replaced by dextromethorphan in cough and cold medicines. Its metabolite, hydromorphone, is sometimes given to treat severe pain. Hydrocodone was first approved by the FDA in 1943 as part of the cough suppressant syrup Hycodan.
Hycodanis the brand name
image of different drug pills on a surface
Hycodan Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Hycodan
Hydrocodone
1943
1122

Approved as Treatment by the FDA

Hydrocodone, otherwise called Hycodan, is approved by the FDA for 2 uses including Pain and Pain .
Pain
Used to treat Severe Pain in combination with Acetaminophen
Pain
Helps manage moderate Pain

Effectiveness

How Hycodan Affects PatientsHydrocodone reduces pain signals sent to both the brain and spinal cord. It can also cause feelings of happiness, slower breathing, and sleepiness.
How Hycodan works in the bodyHydrocodone works by binding to two types of opioid receptors, mu and delta. The mu receptor produces most of the drug's pain relieving effects. When hydrocodone binds to these receptors, it causes nerve cells in the spinal cord to become more relaxed. This dampens pain signals from reaching the brain. Hydrocodone also binds to opioid receptors in the brain and can reduce pain signals from reaching the brain. This drug also blocks inhibitory signals from an area in the brain called the periaquaductal gray, which reduces pain signals from reaching the brain. Hydrocodone also can increase dopamine levels in

When to interrupt dosage

The recommended measure of Hycodan is contingent upon the recognized ailment, including Coughing, Coughing and Chronic Pain. The amount likewise fluctuates as per the technique of delivery (e.g. Tablet, extended release - Oral or Tablet - Oral) featured in the table beneath.
Condition
Dosage
Administration
Acute Bronchitis
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Pain
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Chronic Pain
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Inflammation
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Pain
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Acute Pain
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Rhinitis, Allergic
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Rhinitis
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Common Cold
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Allergic rhinitis (disorder)
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Coughing
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Common Cold
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral
Coughing
7.5 mg, , 5.0 mg, 10.0 mg, 1.0 mg/mL, 5.0 mg/mL, 2.5 mg/mL, 0.75 mg/mL, 0.075 mg/mL, 2.5 mg, 10.0 mg/mL, 15.0 mg, 20.0 mg, 30.0 mg, 40.0 mg, 50.0 mg, 60.0 mg, 80.0 mg, 100.0 mg, 120.0 mg, 0.5 mg/mL, 90.0 mg, 750.0 mg, 45.0 mg, 3.0 mg/mL, 0.33 mg/mL, 1.65 mg/mL, 1.7 mg/mL, 1.667 mg/mL, 1.8 mg/mL, 1.67 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, extended release, Capsule, extended release - Oral, Syrup - Oral, Syrup, Solution, Solution - Oral, Tablet, Tablet - Oral, Suspension, extended release, Suspension, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Kit, Suspension, Suspension - Oral, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Topical, Cream - Topical, Cream, Elixir, Elixir - Oral, Capsule, Capsule - Oral

Warnings

Hycodan Contraindications
Condition
Risk Level
Notes
Intestinal Pseudo-Obstruction
Do Not Combine
Asthma
Do Not Combine
Intracranial Hypertension
Do Not Combine
Status Asthmaticus
Do Not Combine
Asthma
Do Not Combine
increased cerebrospinal pressure
Do Not Combine
Mental Depression
Do Not Combine
Pulmonary Heart Disease
Do Not Combine
Abdomen
Do Not Combine
Epilepsy
Do Not Combine
Pulmonary Disease, Chronic Obstructive
Do Not Combine
ethanol
Do Not Combine
Gastrointestinal obstruction
Do Not Combine
Alcohol Withdrawal Delirium
Do Not Combine
Asthma
Do Not Combine
Hypercarbia
Do Not Combine
Asthma
Do Not Combine
severe CNS depression
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Hydrocodone may interact with Pulse Frequency
There are 20 known major drug interactions with Hycodan.
Common Hycodan Drug Interactions
Drug Name
Risk Level
Description
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Hydrocodone.
Azelastine
Major
Hydrocodone may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Cyclophosphamide
Major
The metabolism of Cyclophosphamide can be decreased when combined with Hydrocodone.
Eluxadoline
Major
The risk or severity of constipation can be increased when Hydrocodone is combined with Eluxadoline.
Enasidenib
Major
The metabolism of Enasidenib can be decreased when combined with Hydrocodone.
Hycodan Toxicity & Overdose RiskTaking too much hydrocodone can lead to an opioid overdose, which can cause breathing difficulty, drowsiness, unconsciousness, weak muscles, cold and clammy skin, small pupils, fluid in the lungs, slow heart rate, low blood pressure, blocked airways, and death. In case of an overdose, the main priority is to keep the airway open and provide assisted breathing if necessary. Other treatments may include fluids, oxygen, and drugs to increase blood pressure. Cardiac arrest or arrhythmias may require advanced life support. Naloxone can be used to reverse the effects of hydrocodone,

Hycodan Novel Uses: Which Conditions Have a Clinical Trial Featuring Hycodan?

50 active clinical trials are currently evaluating the potential of Hycodan to alleviate Chronic Pain, Nasal Congestion due to Common Cold and Acute Bronchitis.
Condition
Clinical Trials
Trial Phases
Acute Pain
2 Actively Recruiting
Early Phase 1, Not Applicable
Chronic Pain
0 Actively Recruiting
Pain
0 Actively Recruiting
Pain
0 Actively Recruiting
Rhinitis, Allergic
0 Actively Recruiting
Acute Bronchitis
5 Actively Recruiting
Phase 4, Not Applicable, Early Phase 1
Common Cold
0 Actively Recruiting
Allergic rhinitis (disorder)
0 Actively Recruiting
Rhinitis
0 Actively Recruiting
Inflammation
0 Actively Recruiting
Coughing
0 Actively Recruiting
Coughing
0 Actively Recruiting
Common Cold
0 Actively Recruiting

Hycodan Reviews: What are patients saying about Hycodan?

5Patient Review
1/9/2013
Hycodan for Cough
This medication was a successful relief from my night time continuous coughing.
5Patient Review
4/14/2011
Hycodan for Cough
This cough medicine was incredibly effective, to the point where my cough was completely gone. However, I started experiencing itchiness all over my body, and while it made me feel sleepy, I kept waking up every 15-20 minutes. It's a shame that I won't be able to use this medication anymore.
5Patient Review
11/21/2011
Hycodan for Cough
This bronchitis medicine was a godsend. I couldn't sleep at all the night before I started taking it, but within 20 minutes of my first dose I found myself feeling so much better. It's also affordable, which is great because my insurance won't cover any cough medicines. Overall, would highly recommend this medication to anyone else suffering from bronchitis!
5Patient Review
4/18/2012
Hycodan for Cough
Super easy to use and provides very quick relief from coughing.
5Patient Review
10/17/2014
Hycodan for Cough
This medication is a great way to address coughing, insomnia and headaches all at once.
View All Reviews

Patient Q&A Section about hycodan

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does Hycodan have hydrocodone in it?

"…a semisynthetic opioid antitussive that acts on the central nervous system."

Answered by AI

What class of drug is Hycodan?

"Opioids are drugs that have a high potential for abuse and dependence. Hydrocodone bitartrate and homatropine methylbromide (Hycodan) is a Schedule III opioid, meaning it has a high potential for abuse but also has legitimate medical uses."

Answered by AI

Is Hycodan and hydrocodone the same?

"Many drugs are commonly prescribed for off label indications in veterinary medicine.

Hydrocodone bitartrate, marketed under the brand names Tussigon®, Hycodan®, Vicodin®, Norco®, and Lortabs®, is an opiate agonist used to treat pain and cough in dogs. Its use in dogs to treat pain and cough is 'off label' or 'extra-label'. Many drugs are commonly prescribed for off label indications in veterinary medicine."

Answered by AI

Clinical Trials for Hycodan

Have you considered Hycodan clinical trials? We made a collection of clinical trials featuring Hycodan, we think they might fit your search criteria.
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