Gastrocrom

Urticaria Pigmentosa, Asthma, Keratoconjunctivitis + 9 more

Treatment

20 Active Studies for Gastrocrom

What is Gastrocrom

Cromoglicic acid

The Generic name of this drug

Treatment Summary

Cromolyn is a medication that blocks the release of chemicals from sensitive mast cells, which can help prevent asthma attacks caused by allergens or exercise. It is a preventative medication and does not help treat an asthma attack that has already started.

Intal

is the brand name

Gastrocrom Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Intal

Cromoglicic acid

1982

45

Effectiveness

How Gastrocrom Affects Patients

Cromoglicate (or cromolyn, USAN) is a man-made compound used to treat asthma and allergic rhinitis. It can also be used as eye drops to treat conjunctivitis and taken orally to treat mastocytosis and ulcerative colitis. Cromoglicate works by blocking the airways from narrowing when it comes into contact with an allergen or irritant that would normally cause an asthma attack.

How Gastrocrom works in the body

Cromoglicate works to prevent allergic reactions by blocking the release of histamine and other inflammatory chemicals from mast cells. This is likely done by preventing calcium from entering the cells.

When to interrupt dosage

The measure of Gastrocrom is contingent upon the recognized malady, such as Urticaria Pigmentosa, Exercise-Induced Bronchospasm and Conjunctivitis, Vernal. The portion of dosage shifts, as indicated by the mode of administration (e.g. Liquid; Spray or Respiratory (inhalation)) featured in the table beneath.

Condition

Dosage

Administration

Urticaria Pigmentosa

, 20.0 mg/mL, 40.0 mg/mL, 100.0 mg/mL, 5.2 mg/mL, 20.0 mg, 2.0 %, 1.0 %, 100.0 mg, 1.0 mg, 5.2 mg, 1.0 mg/dose, 10.0 mg/mL, 0.04 mg/mg, 1.0 mg/pump actuation

, Oral, Liquid, Liquid - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intrabronchial, Solution, Solution - Intrabronchial, Solution, concentrate, Solution, concentrate - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Solution - Oral, Concentrate - Oral, Solution - Ophthalmic, Capsule - Oral, Capsule, Respiratory (inhalation), Solution - Respiratory (inhalation), Liquid - Ophthalmic, Liquid - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered; Solution, Aerosol, metered; Solution - Nasal, Aerosol, metered - Nasal, Powder, Powder - Respiratory (inhalation), Ointment, Ointment - Ophthalmic, Liquid; Spray, Liquid; Spray - Nasal, Spray, Spray - Nasal, Inhalant, Inhalant - Respiratory (inhalation)

Asthma

, 20.0 mg/mL, 40.0 mg/mL, 100.0 mg/mL, 5.2 mg/mL, 20.0 mg, 2.0 %, 1.0 %, 100.0 mg, 1.0 mg, 5.2 mg, 1.0 mg/dose, 10.0 mg/mL, 0.04 mg/mg, 1.0 mg/pump actuation

, Oral, Liquid, Liquid - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intrabronchial, Solution, Solution - Intrabronchial, Solution, concentrate, Solution, concentrate - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Solution - Oral, Concentrate - Oral, Solution - Ophthalmic, Capsule - Oral, Capsule, Respiratory (inhalation), Solution - Respiratory (inhalation), Liquid - Ophthalmic, Liquid - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered; Solution, Aerosol, metered; Solution - Nasal, Aerosol, metered - Nasal, Powder, Powder - Respiratory (inhalation), Ointment, Ointment - Ophthalmic, Liquid; Spray, Liquid; Spray - Nasal, Spray, Spray - Nasal, Inhalant, Inhalant - Respiratory (inhalation)

Keratoconjunctivitis

, 20.0 mg/mL, 40.0 mg/mL, 100.0 mg/mL, 5.2 mg/mL, 20.0 mg, 2.0 %, 1.0 %, 100.0 mg, 1.0 mg, 5.2 mg, 1.0 mg/dose, 10.0 mg/mL, 0.04 mg/mg, 1.0 mg/pump actuation

, Oral, Liquid, Liquid - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intrabronchial, Solution, Solution - Intrabronchial, Solution, concentrate, Solution, concentrate - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Solution - Oral, Concentrate - Oral, Solution - Ophthalmic, Capsule - Oral, Capsule, Respiratory (inhalation), Solution - Respiratory (inhalation), Liquid - Ophthalmic, Liquid - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered; Solution, Aerosol, metered; Solution - Nasal, Aerosol, metered - Nasal, Powder, Powder - Respiratory (inhalation), Ointment, Ointment - Ophthalmic, Liquid; Spray, Liquid; Spray - Nasal, Spray, Spray - Nasal, Inhalant, Inhalant - Respiratory (inhalation)

Bronchospasm, Exercise-Induced

, 20.0 mg/mL, 40.0 mg/mL, 100.0 mg/mL, 5.2 mg/mL, 20.0 mg, 2.0 %, 1.0 %, 100.0 mg, 1.0 mg, 5.2 mg, 1.0 mg/dose, 10.0 mg/mL, 0.04 mg/mg, 1.0 mg/pump actuation

, Oral, Liquid, Liquid - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intrabronchial, Solution, Solution - Intrabronchial, Solution, concentrate, Solution, concentrate - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Solution - Oral, Concentrate - Oral, Solution - Ophthalmic, Capsule - Oral, Capsule, Respiratory (inhalation), Solution - Respiratory (inhalation), Liquid - Ophthalmic, Liquid - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered; Solution, Aerosol, metered; Solution - Nasal, Aerosol, metered - Nasal, Powder, Powder - Respiratory (inhalation), Ointment, Ointment - Ophthalmic, Liquid; Spray, Liquid; Spray - Nasal, Spray, Spray - Nasal, Inhalant, Inhalant - Respiratory (inhalation)

Conjunctivitis, Allergic

, 20.0 mg/mL, 40.0 mg/mL, 100.0 mg/mL, 5.2 mg/mL, 20.0 mg, 2.0 %, 1.0 %, 100.0 mg, 1.0 mg, 5.2 mg, 1.0 mg/dose, 10.0 mg/mL, 0.04 mg/mg, 1.0 mg/pump actuation

, Oral, Liquid, Liquid - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intrabronchial, Solution, Solution - Intrabronchial, Solution, concentrate, Solution, concentrate - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Solution - Oral, Concentrate - Oral, Solution - Ophthalmic, Capsule - Oral, Capsule, Respiratory (inhalation), Solution - Respiratory (inhalation), Liquid - Ophthalmic, Liquid - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered; Solution, Aerosol, metered; Solution - Nasal, Aerosol, metered - Nasal, Powder, Powder - Respiratory (inhalation), Ointment, Ointment - Ophthalmic, Liquid; Spray, Liquid; Spray - Nasal, Spray, Spray - Nasal, Inhalant, Inhalant - Respiratory (inhalation)

Hay Fever

, 20.0 mg/mL, 40.0 mg/mL, 100.0 mg/mL, 5.2 mg/mL, 20.0 mg, 2.0 %, 1.0 %, 100.0 mg, 1.0 mg, 5.2 mg, 1.0 mg/dose, 10.0 mg/mL, 0.04 mg/mg, 1.0 mg/pump actuation

, Oral, Liquid, Liquid - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intrabronchial, Solution, Solution - Intrabronchial, Solution, concentrate, Solution, concentrate - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Solution - Oral, Concentrate - Oral, Solution - Ophthalmic, Capsule - Oral, Capsule, Respiratory (inhalation), Solution - Respiratory (inhalation), Liquid - Ophthalmic, Liquid - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered; Solution, Aerosol, metered; Solution - Nasal, Aerosol, metered - Nasal, Powder, Powder - Respiratory (inhalation), Ointment, Ointment - Ophthalmic, Liquid; Spray, Liquid; Spray - Nasal, Spray, Spray - Nasal, Inhalant, Inhalant - Respiratory (inhalation)

Seasonal Allergic Conjunctivitis

, 20.0 mg/mL, 40.0 mg/mL, 100.0 mg/mL, 5.2 mg/mL, 20.0 mg, 2.0 %, 1.0 %, 100.0 mg, 1.0 mg, 5.2 mg, 1.0 mg/dose, 10.0 mg/mL, 0.04 mg/mg, 1.0 mg/pump actuation

, Oral, Liquid, Liquid - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intrabronchial, Solution, Solution - Intrabronchial, Solution, concentrate, Solution, concentrate - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Solution - Oral, Concentrate - Oral, Solution - Ophthalmic, Capsule - Oral, Capsule, Respiratory (inhalation), Solution - Respiratory (inhalation), Liquid - Ophthalmic, Liquid - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered; Solution, Aerosol, metered; Solution - Nasal, Aerosol, metered - Nasal, Powder, Powder - Respiratory (inhalation), Ointment, Ointment - Ophthalmic, Liquid; Spray, Liquid; Spray - Nasal, Spray, Spray - Nasal, Inhalant, Inhalant - Respiratory (inhalation)

Asthma, Exercise-Induced

, 20.0 mg/mL, 40.0 mg/mL, 100.0 mg/mL, 5.2 mg/mL, 20.0 mg, 2.0 %, 1.0 %, 100.0 mg, 1.0 mg, 5.2 mg, 1.0 mg/dose, 10.0 mg/mL, 0.04 mg/mg, 1.0 mg/pump actuation

, Oral, Liquid, Liquid - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intrabronchial, Solution, Solution - Intrabronchial, Solution, concentrate, Solution, concentrate - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Solution - Oral, Concentrate - Oral, Solution - Ophthalmic, Capsule - Oral, Capsule, Respiratory (inhalation), Solution - Respiratory (inhalation), Liquid - Ophthalmic, Liquid - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered; Solution, Aerosol, metered; Solution - Nasal, Aerosol, metered - Nasal, Powder, Powder - Respiratory (inhalation), Ointment, Ointment - Ophthalmic, Liquid; Spray, Liquid; Spray - Nasal, Spray, Spray - Nasal, Inhalant, Inhalant - Respiratory (inhalation)

Conjunctivitis, Allergic

, 20.0 mg/mL, 40.0 mg/mL, 100.0 mg/mL, 5.2 mg/mL, 20.0 mg, 2.0 %, 1.0 %, 100.0 mg, 1.0 mg, 5.2 mg, 1.0 mg/dose, 10.0 mg/mL, 0.04 mg/mg, 1.0 mg/pump actuation

, Oral, Liquid, Liquid - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intrabronchial, Solution, Solution - Intrabronchial, Solution, concentrate, Solution, concentrate - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Solution - Oral, Concentrate - Oral, Solution - Ophthalmic, Capsule - Oral, Capsule, Respiratory (inhalation), Solution - Respiratory (inhalation), Liquid - Ophthalmic, Liquid - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered; Solution, Aerosol, metered; Solution - Nasal, Aerosol, metered - Nasal, Powder, Powder - Respiratory (inhalation), Ointment, Ointment - Ophthalmic, Liquid; Spray, Liquid; Spray - Nasal, Spray, Spray - Nasal, Inhalant, Inhalant - Respiratory (inhalation)

Rhinitis, Allergic

, 20.0 mg/mL, 40.0 mg/mL, 100.0 mg/mL, 5.2 mg/mL, 20.0 mg, 2.0 %, 1.0 %, 100.0 mg, 1.0 mg, 5.2 mg, 1.0 mg/dose, 10.0 mg/mL, 0.04 mg/mg, 1.0 mg/pump actuation

, Oral, Liquid, Liquid - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intrabronchial, Solution, Solution - Intrabronchial, Solution, concentrate, Solution, concentrate - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Solution - Oral, Concentrate - Oral, Solution - Ophthalmic, Capsule - Oral, Capsule, Respiratory (inhalation), Solution - Respiratory (inhalation), Liquid - Ophthalmic, Liquid - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered; Solution, Aerosol, metered; Solution - Nasal, Aerosol, metered - Nasal, Powder, Powder - Respiratory (inhalation), Ointment, Ointment - Ophthalmic, Liquid; Spray, Liquid; Spray - Nasal, Spray, Spray - Nasal, Inhalant, Inhalant - Respiratory (inhalation)

Hypersensitivity

, 20.0 mg/mL, 40.0 mg/mL, 100.0 mg/mL, 5.2 mg/mL, 20.0 mg, 2.0 %, 1.0 %, 100.0 mg, 1.0 mg, 5.2 mg, 1.0 mg/dose, 10.0 mg/mL, 0.04 mg/mg, 1.0 mg/pump actuation

, Oral, Liquid, Liquid - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intrabronchial, Solution, Solution - Intrabronchial, Solution, concentrate, Solution, concentrate - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Solution - Oral, Concentrate - Oral, Solution - Ophthalmic, Capsule - Oral, Capsule, Respiratory (inhalation), Solution - Respiratory (inhalation), Liquid - Ophthalmic, Liquid - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered; Solution, Aerosol, metered; Solution - Nasal, Aerosol, metered - Nasal, Powder, Powder - Respiratory (inhalation), Ointment, Ointment - Ophthalmic, Liquid; Spray, Liquid; Spray - Nasal, Spray, Spray - Nasal, Inhalant, Inhalant - Respiratory (inhalation)

Food Hypersensitivity

, 20.0 mg/mL, 40.0 mg/mL, 100.0 mg/mL, 5.2 mg/mL, 20.0 mg, 2.0 %, 1.0 %, 100.0 mg, 1.0 mg, 5.2 mg, 1.0 mg/dose, 10.0 mg/mL, 0.04 mg/mg, 1.0 mg/pump actuation

, Oral, Liquid, Liquid - Oral, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intrabronchial, Solution, Solution - Intrabronchial, Solution, concentrate, Solution, concentrate - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Solution - Oral, Concentrate - Oral, Solution - Ophthalmic, Capsule - Oral, Capsule, Respiratory (inhalation), Solution - Respiratory (inhalation), Liquid - Ophthalmic, Liquid - Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered; Solution, Aerosol, metered; Solution - Nasal, Aerosol, metered - Nasal, Powder, Powder - Respiratory (inhalation), Ointment, Ointment - Ophthalmic, Liquid; Spray, Liquid; Spray - Nasal, Spray, Spray - Nasal, Inhalant, Inhalant - Respiratory (inhalation)

Warnings

There are 1 known major drug interactions with Gastrocrom.

Common Gastrocrom Drug Interactions

Drug Name

Risk Level

Description

Methacholine

Minor

Cromoglicic acid may decrease effectiveness of Methacholine as a diagnostic agent.

Gastrocrom Toxicity & Overdose Risk

Signs of an overdose on azelastine include coughing, stuffy nose, nausea, sneezing, and difficulty breathing.

Gastrocrom Novel Uses: Which Conditions Have a Clinical Trial Featuring Gastrocrom?

157 active studies are currently exploring the potential of Gastrocrom to ameliorate Asthma, Vernal Keratoconjunctivitis and Seasonal Allergic Conjunctivitis.

Condition

Clinical Trials

Trial Phases

Asthma

92 Actively Recruiting

Phase 1, Phase 4, Early Phase 1, Phase 2, Not Applicable, Phase 3

Conjunctivitis, Allergic

1 Actively Recruiting

Phase 2

Keratoconjunctivitis

0 Actively Recruiting

Rhinitis, Allergic

0 Actively Recruiting

Food Hypersensitivity

0 Actively Recruiting

Hypersensitivity

0 Actively Recruiting

Urticaria Pigmentosa

0 Actively Recruiting

Bronchospasm, Exercise-Induced

0 Actively Recruiting

Seasonal Allergic Conjunctivitis

0 Actively Recruiting

Conjunctivitis, Allergic

0 Actively Recruiting

Hay Fever

0 Actively Recruiting

Asthma, Exercise-Induced

0 Actively Recruiting

Gastrocrom Reviews: What are patients saying about Gastrocrom?

5

Patient Review

1/3/2010

Gastrocrom for Allergy to Food that causes Problems of the Stomach or Intestines

Gastrocrom has been a total life-saver for my son who suffers from mastocytosis. It took less than a week of regular use to get his digestive system back on track, and the difference is noticeable if he misses even just one dose. We've also found that it works great as a lotion to relieve itchiness caused by both mastocytosis and eczema.

5

Patient Review

9/9/2011

Gastrocrom for Allergy to Food that causes Problems of the Stomach or Intestines

This regimen has given me my life back! I suffered for 9 years with chronic nausea and abdominal pain. In the past 6 weeks I've only had two episodes of mild nausea and only treated one. I was sick every day, all day triggered by food sensitivities that I was unaware of and discovered accidently ( ex soy, dairy)

5

Patient Review

4/22/2014

Gastrocrom for Condition of Increased Mast Cells

I cannot believe how well this drug works. For years I've been dealing with nausea as soon as I got out of bed in the morning, and it would last all day long. It was like having mild to severe motion sickness. But within half an hour of taking this medication, along with Zantac and Benadryl, my symptoms were completely gone.

5

Patient Review

1/28/2017

Gastrocrom for Allergy to Food that causes Problems of the Stomach or Intestines

Even though it's expensive and not covered by insurance, this treatment really helped me. More than antihistamines or zantac 150.

5

Patient Review

1/23/2017

Gastrocrom for Condition of Increased Mast Cells

I'm only on day three, but I feel so much better already. Fingers crossed this keeps up!

5

Patient Review

8/2/2013

Gastrocrom for Inflammatory Bowel Disease

This medication is nothing short of miraculous. It completely alleviated my extra-intestinal symptoms of Crohn's disease, like eye inflammations and poly-arthritis!

4.7

Patient Review

3/23/2016

Gastrocrom for Allergy to Food that causes Problems of the Stomach or Intestines

I've had years of trouble with a restricted diet and allergies, but this medication has given me significant relief. It's really allowed me to enjoy food again without as many problems. I can't imagine my life without it!

4.7

Patient Review

1/27/2012

Gastrocrom for Condition of Increased Mast Cells

Medco always sends the correct amount of medication that my doctor ordered. They also send partial boxes in addition to full boxes.

4.7

Patient Review

8/21/2012

Gastrocrom for Allergy to Food that causes Problems of the Stomach or Intestines

This medication was immediately effective, whereas I had been taking prilosex for acid reflux which still did not provide relief.

4.3

Patient Review

9/9/2009

Gastrocrom for Allergy to Food that causes Problems of the Stomach or Intestines

gastrocrom has been prescribed for my 4 year old son who also has autism and other non-ige mediated food allergies. He has less complaints of tummy aches and it has also decreased his vomiting episodes.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about gastrocrom

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What kind of drug is cromolyn?

"Cromolyn is a medication that prevents mast cells from releasing substances that can cause skin and gut problems."

Answered by AI

Is Gastrocrom an antihistamine?

"Cromolyn (Gastrocrom) is not an antihistamine, but it prevents your mast cells from releasing too much histamine, a chemical created by your body's immune system."

Answered by AI

What does Gastrocrom treat?

"FDA has approved Gastrocrom to treat mastocytosis. It is suitable for adults and children aged 2 or above. Mastocytosis is a condition where the body produces too many mast cells. A mast cell is a type of white blood cell."

Answered by AI

How much does Gastrocrom cost?

"How much will you pay for Gastrocrom if you don't have insurance? If you don't have insurance, you will have to pay $1,274.64 for a Gastrocrom prescription. However, if you use a SingleCare Gastrocrom coupon, you will only have to pay $125.09 per 5, 5ML of 100MG/5ML Concentrate."

Answered by AI

Clinical Trials for Gastrocrom

Have you considered Gastrocrom clinical trials?

We made a collection of clinical trials featuring Gastrocrom, we think they might fit your search criteria.
Go to Trials
Image of Allergy Immunology Associates in Mayfield Heights, United States.

Osteopathic Manipulative Treatment for Asthma

18 - 60
All Sexes
Mayfield Heights, OH

Asthma is a common respiratory condition that can be difficult to control despite the use of medications such as inhalers, oral steroids or even injectable medications. Osteopathic Manipulative Treatment (OMT) is a hands-on technique used to improve the chest structure and function and may help in improving breathing. Previous research showed that OMT in asthma patients, can improve the movement of the ribs and improve the "peak flow" which is the maximum rate at which a person can exhale air after taking a deep breath. However, no studies have evaluated the impact of OMT on lung inflammation. This single-site research study at University Hospitals aims to evaluate whether Osteopathic Manipulative Treatment (OMT) can reduce lung inflammation and improve breathing and lung function in adult patients with asthma. The lung function will be evaluated by Spirometry which is a test that measures how much air you can breathe in and out of your lungs, as well as how quickly and easily you can exhale air. The lung inflammation will be measured using a device that can detect how much you are breathing out Nitric Oxide which is a gas produced by inflamed cells in the lungs, this test is called: Fractional exhaled Nitric Oxide or FeNO. Approximately 100 participants will be enrolled.

Waitlist Available
Has No Placebo

Allergy Immunology Associates

Nancy Wasserbauer-Kingston, DO

Image of DARTNet Institute in Aurora, United States.

Inhaled Corticosteroids + Azithromycin for Asthma

13 - 75
All Sexes
Aurora, CO

While asthma therapy is becoming more individualized based on asthma phenotypes, more research is needed to tailor newer therapies to individuals. Inhaled corticosteroid (ICS) medications are the foundation of care for all individuals with persistent asthma. But ICS use is not without possible long term side effects. This study will compare two currently available approaches to reduce AEX in primary care patients: (1) use of inhaled corticosteroids (ICS) as part of rescue therapy, also known as MART (Maintenance And Reliever Therapy) or PARTICS (Patient Activated Reliever Trigger Inhaled Corticosteriods) therapy - either of these therapies will be called Rescue-Inhaled Corticosteroids or R-ICS pronounced "Ricks," and (2) use of azithromycin (AZ) as a preventive therapy. These treatments will be studied both individually and in combination.

Phase 4
Recruiting

DARTNet Institute (+12 Sites)

Wilson D Pace, MD, FAAFP

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We made a collection of clinical trials featuring Gastrocrom, we think they might fit your search criteria.
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Image of Velocity Clinical Research, Mobile in Mobile, United States.

PF-07275315 for Asthma

18 - 70
All Sexes
Mobile, AL

The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called PF-07275315) for the potential treatment of moderate-to-severe asthma. Asthma is a condition that makes it challenging to breathe, which negatively impacts the quality of life and functioning of people who are affected. This study is seeking participants who: * Are 18 to 70 years old * Have had moderate-to-severe asthma for at least 12 months that is not well controlled * Have been taking their regular maintenance treatment(s) for asthma over the last 12 months All participants will receive PF-07275315 or a placebo. A placebo does not have any medicine in it but looks just like the medicine being studied. PF-07275315 or placebo will be given as multiple shots in the clinic over the course of 12 weeks. We will compare the experiences of people receiving PF-07275315 to those of the people who do not. This will help us determine if PF-07275315 is safe and effective. Participants will be involved in this study for about 9.5 months. During this time, they will have 10 visits at the study clinic.

Phase 2
Recruiting

Velocity Clinical Research, Mobile (+10 Sites)

Pfizer CT.gov Call Center

Pfizer

Image of St. Joseph's Healthcare Hamilton in Hamilton, Canada.

Corticosteroids for Asthma

18+
All Sexes
Hamilton, Canada

Most individuals with asthma can effectively manage their symptoms and maintain normal lung function using inhaled medications, unfortunately, there is a subset of asthma sufferers whose symptoms, lung function, and risk of asthma attacks remain unimproved despite conventional inhaled medications. There could be several reasons for this. One possibility is that inhaled medications fail to reach the intended areas within the lungs, due to structural abnormalities within the airways themselves. Much like road conditions or closures can impede the speed and efficiency of vehicle travel, factors such as airway narrowing or mucus blockages, which are common in asthma, can obstruct the passage of inhaled medications through the airways. Our team has now optimized advanced medical imaging techniques, including magnetic resonance imaging (MRI) and computed tomography (CT), required to investigate this. This study will use these imaging methods to visually assess and measure individual patients' airways and determine whether abnormal airway structures impact how well they respond to inhaled and orally delivered medications. We anticipate finding that abnormal airway structures make inhaled medications less effective, but that they do not affect the response to oral medications.

Phase 4
Recruiting

St. Joseph's Healthcare Hamilton (+1 Sites)

Have you considered Gastrocrom clinical trials?

We made a collection of clinical trials featuring Gastrocrom, we think they might fit your search criteria.
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